메뉴 건너뛰기




Volumn 123, Issue 2, 2018, Pages 288-300

Stem cell therapy for hypoplastic left heart syndrome mechanism, clinical application, and future directions

Author keywords

Cell transplantation; Heart failure; Hypoplastic left heart syndrome; Myocardial infarction; Stem cells

Indexed keywords

STEM CELL FACTOR;

EID: 85056488795     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.311206     Document Type: Review
Times cited : (35)

References (102)
  • 3
    • 76649118471 scopus 로고    scopus 로고
    • Mortality in first 5 years in infants with functional single ventricle born in Texas, 1996 to 2003
    • Fixler DE, Nembhard WN, Salemi JL, Ethen MK, Canfield MA. Mortality in first 5 years in infants with functional single ventricle born in Texas, 1996 to 2003. Circulation. 2010;121:644-650. doi: 10.1161/CIRCULATIONAHA.109.881904.
    • (2010) Circulation , vol.121 , pp. 644-650
    • Fixler, D.E.1    Nembhard, W.N.2    Salemi, J.L.3    Ethen, M.K.4    Canfield, M.A.5
  • 4
    • 49349091793 scopus 로고    scopus 로고
    • Decreasing number of deaths of infants with hypoplastic left heart syndrome
    • Gordon BM, Rodriguez S, Lee M, Chang RK. Decreasing number of deaths of infants with hypoplastic left heart syndrome. J Pediatr. 2008;153:354-358. doi: 10.1016/j.jpeds.2008.03.009.
    • (2008) J Pediatr , vol.153 , pp. 354-358
    • Gordon, B.M.1    Rodriguez, S.2    Lee, M.3    Chang, R.K.4
  • 5
    • 56049102822 scopus 로고    scopus 로고
    • Prevalence of congenital heart defects in metropolitan Atlanta, 1998-2005
    • Reller MD, Strickland MJ, Riehle-Colarusso T, Mahle WT, Correa A. Prevalence of congenital heart defects in metropolitan Atlanta, 1998-2005. J Pediatr. 2008;153:807-813. doi: 10.1016/j.jpeds.2008.05.059.
    • (2008) J Pediatr , vol.153 , pp. 807-813
    • Reller, M.D.1    Strickland, M.J.2    Riehle-Colarusso, T.3    Mahle, W.T.4    Correa, A.5
  • 6
    • 84904968728 scopus 로고    scopus 로고
    • Heart failure in children: Etiology and treatment
    • Rossano JW, Shaddy RE. Heart failure in children: etiology and treatment. J Pediatr. 2014;165:228-233. doi: 10.1016/j.jpeds.2014.04.055.
    • (2014) J Pediatr , vol.165 , pp. 228-233
    • Rossano, J.W.1    Shaddy, R.E.2
  • 7
    • 33746926386 scopus 로고    scopus 로고
    • Comparison of the epidemiology and co-morbidities of heart failure in the pediatric and adult populations: A retrospective, cross-sectional study
    • Webster G, Zhang J, Rosenthal D. Comparison of the epidemiology and co-morbidities of heart failure in the pediatric and adult populations: a retrospective, cross-sectional study. BMC Cardiovasc Disord. 2006;6:23. doi: 10.1186/1471-2261-6-23.
    • (2006) BMC Cardiovasc Disord , vol.6 , pp. 23
    • Webster, G.1    Zhang, J.2    Rosenthal, D.3
  • 8
    • 54049093680 scopus 로고    scopus 로고
    • Two-year survival and mental and psychomotor outcomes after the Norwood procedure: An analysis of the modified Blalock-Taussig shunt and right ventricle-to-pulmonary artery shunt surgical eras
    • Atallah J, Dinu IA, Joffe AR, Robertson CM, Sauve RS, Dyck JD, Ross DB, Rebeyka IM; tWestern Canadian Complex Pediatric Therapies Follow-Up Group. Two-year survival and mental and psychomotor outcomes after the Norwood procedure: an analysis of the modified Blalock-Taussig shunt and right ventricle-to-pulmonary artery shunt surgical eras. Circulation. 2008;118:1410-1418. doi: 10.1161/CIRCULATIONAHA.107.741579.
    • (2008) Circulation , vol.118 , pp. 1410-1418
    • Atallah, J.1    Dinu, I.A.2    Joffe, A.R.3    Robertson, C.M.4    Sauve, R.S.5    Dyck, J.D.6    Ross, D.B.7    Rebeyka, I.M.8
  • 9
    • 0034332865 scopus 로고    scopus 로고
    • Two-dimensional echocardiographic assessment of right ventricular function in hypoplastic left heart syndrome
    • Altmann K, Printz BF, Solowiejczky DE, Gersony WM, Quaegebeur J, Apfel HD. Two-dimensional echocardiographic assessment of right ventricular function in hypoplastic left heart syndrome. Am J Cardiol. 2000;86:964-968.
    • (2000) Am J Cardiol , vol.86 , pp. 964-968
    • Altmann, K.1    Printz, B.F.2    Solowiejczky, D.E.3    Gersony, W.M.4    Quaegebeur, J.5    Apfel, H.D.6
  • 10
    • 85031018335 scopus 로고    scopus 로고
    • Stem cell therapy for the systemic right ventricle
    • Si MS, Ohye RG. Stem cell therapy for the systemic right ventricle. Expert Rev Cardiovasc Ther. 2017;15:813-823. doi: 10.1080/14779072. 2017.1379898.
    • (2017) Expert Rev Cardiovasc Ther , vol.15 , pp. 813-823
    • Si, M.S.1    Ohye, R.G.2
  • 13
    • 0000062301 scopus 로고
    • Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells
    • Becker AJ, Mcculloch EA, Till JE. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature. 1963;197:452-454.
    • (1963) Nature , vol.197 , pp. 452-454
    • Becker, A.J.1    Mcculloch, E.A.2    Till, J.E.3
  • 14
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement
    • Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop Dj, Horwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315-317. doi: 10.1080/14653240600855905.
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3    Slaper-Cortenbach, I.4    Marini, F.5    Krause, D.6    Deans, R.7    Keating, A.8    Dj, P.9    Horwitz, E.10
  • 15
    • 33646252939 scopus 로고    scopus 로고
    • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
    • Gnecchi M, He H, Noiseux N, Liang OD, Zhang L, Morello F, Mu H, Melo LG, Pratt RE, Ingwall JS, Dzau VJ. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. FASEB J. 2006;20:661-669. doi: 10.1096/fj.05-5211com.
    • (2006) FASEB J , vol.20 , pp. 661-669
    • Gnecchi, M.1    He, H.2    Noiseux, N.3    Liang, O.D.4    Zhang, L.5    Morello, F.6    Mu, H.7    Melo, L.G.8    Pratt, R.E.9    Ingwall, J.S.10    Dzau, V.J.11
  • 16
    • 53249127066 scopus 로고    scopus 로고
    • Immuno-inflammatory regulation effect of mesenchymal stem cell transplantation in a rat model of myocardial infarction
    • Du YY, Zhou SH, Zhou T, Su H, Pan HW, Du WH, Liu B, Liu QM. Immuno-inflammatory regulation effect of mesenchymal stem cell transplantation in a rat model of myocardial infarction. Cytotherapy. 2008;10:469-478. doi: 10.1080/14653240802129893.
    • (2008) Cytotherapy , vol.10 , pp. 469-478
    • Du, Y.Y.1    Zhou, S.H.2    Zhou, T.3    Su, H.4    Pan, H.W.5    Du, W.H.6    Liu, B.7    Liu, Q.M.8
  • 17
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005;105:1815-1822. doi: 10.1182/blood-2004-04-1559.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 19
    • 84870887067 scopus 로고    scopus 로고
    • Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: The POSEIDON randomized trial
    • Hare JM, Fishman JE, Gerstenblith G, et al. Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial. JAMA. 2012;308:2369-2379. doi: 10.1001/jama.2012.25321.
    • (2012) JAMA , vol.308 , pp. 2369-2379
    • Hare, J.M.1    Fishman, J.E.2    Gerstenblith, G.3
  • 20
    • 85011650223 scopus 로고    scopus 로고
    • Randomized comparison of allogeneic versus autologous mesenchymal stem cells for nonischemic dilated cardiomyopathy: POSEIDON-DCM trial
    • Hare JM, DiFede DL, Rieger AC, et al. Randomized comparison of allogeneic versus autologous mesenchymal stem cells for nonischemic dilated cardiomyopathy: POSEIDON-DCM trial. J Am Coll Cardiol. 2017;69:526-537. doi: 10.1016/j.jacc.2016.11.009.
    • (2017) J Am Coll Cardiol , vol.69 , pp. 526-537
    • Hare, J.M.1    DiFede, D.L.2    Rieger, A.C.3
  • 21
    • 0033786310 scopus 로고    scopus 로고
    • Current status of umbilical cord blood hematopoietic stem cell transplantation
    • E G
    • E G. Current status of umbilical cord blood hematopoietic stem cell transplantation. Experimental Hematology. 2000;28:1197-1205.
    • (2000) Experimental Hematology , vol.28 , pp. 1197-1205
  • 22
    • 1442356953 scopus 로고    scopus 로고
    • Isolation of multipotent mesenchymal stem cells from umbilical cord blood
    • Lee OK, Kuo TK, Chen WM, Lee KD, Hsieh SL, Chen TH. Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood. 2004;103:1669-1675. doi: 10.1182/blood-2003-05-1670.
    • (2004) Blood , vol.103 , pp. 1669-1675
    • Lee, O.K.1    Kuo, T.K.2    Chen, W.M.3    Lee, K.D.4    Hsieh, S.L.5    Chen, T.H.6
  • 23
    • 33750157480 scopus 로고    scopus 로고
    • Differentiation of umbilical cord blood-derived multi-lineage progenitor cells into respiratory epithelial cells
    • Berger MJ, Adams SD, Tigges BM, Sprague SL, Wang XJ, Collins DP, McKenna DH. Differentiation of umbilical cord blood-derived multi-lineage progenitor cells into respiratory epithelial cells. Cytotherapy. 2006;8:480-487. doi: 10.1080/14653240600941549.
    • (2006) Cytotherapy , vol.8 , pp. 480-487
    • Berger, M.J.1    Adams, S.D.2    Tigges, B.M.3    Sprague, S.L.4    Wang, X.J.5    Collins, D.P.6    McKenna, D.H.7
  • 26
    • 72049101445 scopus 로고    scopus 로고
    • Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload
    • Yerebakan C, Sandica E, Prietz S, et al. Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload. Cell Transplant. 2009;18:855-868. doi: 10.3727/096368909X471170.
    • (2009) Cell Transplant , vol.18 , pp. 855-868
    • Yerebakan, C.1    Sandica, E.2    Prietz, S.3
  • 28
    • 85032618937 scopus 로고    scopus 로고
    • Safety and efficacy of the intravenous infusion of umbilical cord mesenchymal stem cells in patients with heart failure: A phase ½ randomized controlled trial (RIMECARD trial [Randomized clinical trial of intravenous infusion umbilical cord mesenchymal stem cells on cardiopathy])
    • Bartolucci J, Verdugo FJ, González PL, et al. Safety and efficacy of the intravenous infusion of umbilical cord mesenchymal stem cells in patients with heart failure: a phase ½ randomized controlled trial (RIMECARD trial [Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy]). Circ Res. 2017;121:1192-1204. doi: 10.1161/CIRCRESAHA.117.310712.
    • (2017) Circ Res , vol.121 , pp. 1192-1204
    • Bartolucci, J.1    Verdugo, F.J.2    González, P.L.3
  • 29
    • 84878682260 scopus 로고    scopus 로고
    • Human cardiospheres as a source of multipotent stem and progenitor cells
    • Barile L, Gherghiceanu M, Popescu LM, Moccetti T, Vassalli G. Human cardiospheres as a source of multipotent stem and progenitor cells. Stem Cells Int. 2013;2013:916837. doi: 10.1155/2013/916837.
    • (2013) Stem Cells Int , vol.2013 , pp. 916837
    • Barile, L.1    Gherghiceanu, M.2    Popescu, L.M.3    Moccetti, T.4    Vassalli, G.5
  • 30
    • 77950890007 scopus 로고    scopus 로고
    • Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    • Chimenti I, Smith RR, Li TS, Gerstenblith G, Messina E, Giacomello A, Marbán E. Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res. 2010;106:971-980. doi: 10.1161/CIRCRESAHA. 109.210682.
    • (2010) Circ Res , vol.106 , pp. 971-980
    • Chimenti, I.1    Smith, R.R.2    Li, T.S.3    Gerstenblith, G.4    Messina, E.5    Giacomello, A.6    Marbán, E.7
  • 33
    • 84930665588 scopus 로고    scopus 로고
    • Cellular postconditioning: Allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction
    • Kanazawa H, Tseliou E, Malliaras K, et al. Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction. Circ Heart Fail. 2015;8:322-332. doi: 10.1161/CIRCHEARTFAILURE.114.001484.
    • (2015) Circ Heart Fail , vol.8 , pp. 322-332
    • Kanazawa, H.1    Tseliou, E.2    Malliaras, K.3
  • 37
    • 77649202748 scopus 로고    scopus 로고
    • Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarction
    • Tang XL, Rokosh DG, Guo Y, Bolli R. Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarction. Circ J. 2010;74:390-404.
    • (2010) Circ J , vol.74 , pp. 390-404
    • Tang, X.L.1    Rokosh, D.G.2    Guo, Y.3    Bolli, R.4
  • 40
    • 82155181992 scopus 로고    scopus 로고
    • Human cardiac stem cells isolated from atrial appendages stably express c-kit
    • He JQ, Vu DM, Hunt G, Chugh A, Bhatnagar A, Bolli R. Human cardiac stem cells isolated from atrial appendages stably express c-kit. PLoS One. 2011;6:e27719. doi: 10.1371/journal.pone.0027719.
    • (2011) PLoS One , vol.6
    • He, J.Q.1    Vu, D.M.2    Hunt, G.3    Chugh, A.4    Bhatnagar, A.5    Bolli, R.6
  • 41
    • 85004190309 scopus 로고    scopus 로고
    • A deep proteome analysis identifies the complete secretome as the functional unit of human cardiac progenitor cells
    • Sharma S, Mishra R, Bigham GE, et al. A deep proteome analysis identifies the complete secretome as the functional unit of human cardiac progenitor cells. Circ Res. 2017;120:816-834. doi: 10.1161/CIRCRESAHA.116.309782.
    • (2017) Circ Res , vol.120 , pp. 816-834
    • Sharma, S.1    Mishra, R.2    Bigham, G.E.3
  • 42
    • 84976349093 scopus 로고    scopus 로고
    • Age-dependent effect of pediatric cardiac progenitor cells after juvenile heart failure
    • Agarwal U, Smith AW, French KM, et al. Age-dependent effect of pediatric cardiac progenitor cells after juvenile heart failure. Stem Cells Transl Med. 2016;5:883-892. doi: 10.5966/sctm.2015-0241.
    • (2016) Stem Cells Transl Med , vol.5 , pp. 883-892
    • Agarwal, U.1    Smith, A.W.2    French, K.M.3
  • 43
    • 85000631212 scopus 로고    scopus 로고
    • Experimental, systems, and computational approaches to understanding the microrna-mediated reparative potential of cardiac progenitor cell-derived exosomes from pediatric patients
    • Agarwal U, George A, Bhutani S, Ghosh-Choudhary S, Maxwell JT, Brown ME, Mehta Y, Platt MO, Liang Y, Sahoo S, Davis ME. Experimental, systems, and computational approaches to understanding the microrna-mediated reparative potential of cardiac progenitor cell-derived exosomes from pediatric patients. Circ Res. 2017;120:701-712. doi: 10.1161/CIRCRESAHA.116.309935.
    • (2017) Circ Res , vol.120 , pp. 701-712
    • Agarwal, U.1    George, A.2    Bhutani, S.3    Ghosh-Choudhary, S.4    Maxwell, J.T.5    Brown, M.E.6    Mehta, Y.7    Platt, M.O.8    Liang, Y.9    Sahoo, S.10    Davis, M.E.11
  • 44
    • 82255175382 scopus 로고    scopus 로고
    • Cardiac stem cells in patients with ischaemic cardiomyopathy (Scipio): Initial results of a randomised phase 1 trial
    • Bolli R, Chugh AR, D'Amario D, et al. Cardiac Stem Cells in Patients With Ischaemic Cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet. 2011;378:1847-1857. doi: 10.1016/S0140-6736(11)61590-0.
    • (2011) Lancet , vol.378 , pp. 1847-1857
    • Bolli, R.1    Chugh, A.R.2    D'Amario, D.3
  • 47
    • 0033153242 scopus 로고    scopus 로고
    • On the human left ventricular shape
    • Azhari H, Beyar R, Sideman S. On the human left ventricular shape. Comput Biomed Res. 1999;32:264-282. doi: 10.1006/cbmr.1999.1513.
    • (1999) Comput Biomed Res , vol.32 , pp. 264-282
    • Azhari, H.1    Beyar, R.2    Sideman, S.3
  • 48
    • 0020051991 scopus 로고
    • Left ventricular diastolic suction as a mechanism of ventricular filling
    • Hori M, Yeliin EL, Sonnenblick EH. Left ventricular diastolic suction as a mechanism of ventricular filling. Jpn Circ J. 1982;46:124-129.
    • (1982) Jpn Circ J , vol.46 , pp. 124-129
    • Hori, M.1    Yeliin, E.L.2    Sonnenblick, E.H.3
  • 49
    • 76749153746 scopus 로고    scopus 로고
    • The right ventricle and pulmonary circulation: Basic concepts
    • CR G. The right ventricle and pulmonary circulation: basic concepts. Rev Esp Cardiol. 2010;63:81-95.
    • (2010) Rev Esp Cardiol , vol.63 , pp. 81-95
    • Cr, G.1
  • 50
    • 0025954623 scopus 로고
    • The right ventricle: Anatomy, physiology, and clinical importance
    • Dell'Italia LJ. The right ventricle: anatomy, physiology, and clinical importance. Curr Probl Cardiol. 1991;16:653-720.
    • (1991) Curr Probl Cardiol , vol.16 , pp. 653-720
    • Dell'Italia, L.J.1
  • 51
    • 0029741850 scopus 로고    scopus 로고
    • Ventricular myoarchitecture in tetralogy of Fallot
    • Sanchez-Quintana D, Anderson RH, Ho SY. Ventricular myoarchitecture in tetralogy of Fallot. Heart. 1996;76:280-286.
    • (1996) Heart , vol.76 , pp. 280-286
    • Sanchez-Quintana, D.1    Anderson, R.H.2    Ho, S.Y.3
  • 53
    • 0030926093 scopus 로고    scopus 로고
    • The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: The role of ingression and tissue movement during gastrulation
    • Tam PP, Parameswaran M, Kinder SJ, Weinberger RP. The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation. Development. 1997;124:1631-1642.
    • (1997) Development , vol.124 , pp. 1631-1642
    • Tam, P.P.1    Parameswaran, M.2    Kinder, S.J.3    Weinberger, R.P.4
  • 54
    • 84921954526 scopus 로고    scopus 로고
    • Molecular regulation of cardiomyocyte differentiation
    • Paige SL, Plonowska K, Xu A, Wu SM. Molecular regulation of cardiomyocyte differentiation. Circ Res. 2015;116:341-353. doi: 10.1161/CIRCRESAHA.116.302752.
    • (2015) Circ Res , vol.116 , pp. 341-353
    • Paige, S.L.1    Plonowska, K.2    Xu, A.3    Wu, S.M.4
  • 58
    • 13444310919 scopus 로고    scopus 로고
    • The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner
    • McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN. The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development. 2005;132:189-201. doi: 10.1242/dev.01562.
    • (2005) Development , vol.132 , pp. 189-201
    • McFadden, D.G.1    Barbosa, A.C.2    Richardson, J.A.3    Schneider, M.D.4    Srivastava, D.5    Olson, E.N.6
  • 59
    • 33751542475 scopus 로고    scopus 로고
    • Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors
    • Rutenberg JB, Fischer A, Jia H, Gessler M, Zhong TP, Mercola M. Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors. Development. 2006;133:4381-4390. doi: 10.1242/dev.02607.
    • (2006) Development , vol.133 , pp. 4381-4390
    • Rutenberg, J.B.1    Fischer, A.2    Jia, H.3    Gessler, M.4    Zhong, T.P.5    Mercola, M.6
  • 60
    • 84857004535 scopus 로고    scopus 로고
    • Coordinating tissue interactions: Notch signaling in cardiac development and disease
    • de la Pompa JL, Epstein JA. Coordinating tissue interactions: Notch signaling in cardiac development and disease. Dev cell. 2012;22: 244-254.
    • (2012) Dev Cell , vol.22 , pp. 244-254
    • De La Pompa, J.L.1    Epstein, J.A.2
  • 63
    • 55749112329 scopus 로고    scopus 로고
    • Notch1 regulates the fate of cardiac progenitor cells
    • Boni A, Urbanek K, Nascimbene A,et al. Notch1 regulates the fate of cardiac progenitor cells. Proc Natl Acad Sci USA. 2008;105:15529-15534.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15529-15534
    • Boni, A.1    Urbanek, K.2    Nascimbene, A.3
  • 64
    • 61949160625 scopus 로고    scopus 로고
    • Hypoplastic left heart syndrome links to chromosomes 10q and 6q and is genetically related to bicuspid aortic valve
    • Hinton RB, Martin LJ, Rame-Gowda S, Tabangin ME, Cripe LH, Benson DW. Hypoplastic left heart syndrome links to chromosomes 10q and 6q and is genetically related to bicuspid aortic valve. J Am Coll Cardiol. 2009;53:1065-1071. doi: 10.1016/j.jacc.2008.12.023.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1065-1071
    • Hinton, R.B.1    Martin, L.J.2    Rame-Gowda, S.3    Tabangin, M.E.4    Cripe, L.H.5    Benson, D.W.6
  • 66
    • 84904608539 scopus 로고    scopus 로고
    • Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome
    • Kobayashi J, Yoshida M, Tarui S, Hirata M, Nagai Y, Kasahara S, Naruse K, Ito H, Sano S, Oh H. Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome. PLoS One. 2014;9:e102796. doi: 10.1371/journal.pone.0102796.
    • (2014) PLoS One , vol.9
    • Kobayashi, J.1    Yoshida, M.2    Tarui, S.3    Hirata, M.4    Nagai, Y.5    Kasahara, S.6    Naruse, K.7    Ito, H.8    Sano, S.9    Oh, H.10
  • 67
    • 84860703695 scopus 로고    scopus 로고
    • Wnt5a and Wnt11 are essential for second heart field progenitor development
    • Cohen ED, Miller MF, Wang Z, Moon RT, Morrisey EE. Wnt5a and Wnt11 are essential for second heart field progenitor development. Development. 2012;139:1931-1940. doi: 10.1242/dev.069377.
    • (2012) Development , vol.139 , pp. 1931-1940
    • Cohen, E.D.1    Miller, M.F.2    Wang, Z.3    Moon, R.T.4    Morrisey, E.E.5
  • 68
    • 72049100179 scopus 로고    scopus 로고
    • Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression
    • Nagy II, Railo A, Rapila R, Hast T, Sormunen R, Tavi P, Räsänen J, Vainio SJ. Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression. Cardiovasc Res. 2010;85:100-109. doi: 10.1093/cvr/cvp254.
    • (2010) Cardiovasc Res , vol.85 , pp. 100-109
    • Nagy, I.I.1    Railo, A.2    Rapila, R.3    Hast, T.4    Sormunen, R.5    Tavi, P.6    Räsänen, J.7    Vainio, S.J.8
  • 70
    • 84902950611 scopus 로고    scopus 로고
    • The right ventricle in pulmonary arterial hypertension: Disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure
    • Ryan JJ, Archer SL. The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circ Res. 2014;115:176-188. doi: 10.1161/CIRCRESAHA.113.301129.
    • (2014) Circ Res , vol.115 , pp. 176-188
    • Ryan, J.J.1    Archer, S.L.2
  • 72
    • 1442324702 scopus 로고    scopus 로고
    • Morphometry of coronary capillaries in hypoplastic left heart syndrome
    • discussion 907.
    • Salih C, Sheppard MN, Ho SY. Morphometry of coronary capillaries in hypoplastic left heart syndrome. Ann Thorac Surg. 2004;77:903-907; discussion 907. doi: 10.1016/j.athoracsur.2003.07.046.
    • (2004) Ann Thorac Surg , vol.77 , pp. 903-907
    • Salih, C.1    Sheppard, M.N.2    Ho, S.Y.3
  • 73
    • 84888636768 scopus 로고    scopus 로고
    • A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension
    • Berl
    • Sutendra G, Dromparis P, Paulin R, Zervopoulos S, Haromy A, Nagendran J and Michelakis ED. A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension. J Mol Med (Berl). 2013;91:1315-1327.
    • (2013) J Mol Med , vol.91 , pp. 1315-1327
    • Sutendra, G.1    Dromparis, P.2    Paulin, R.3    Zervopoulos, S.4    Haromy, A.5    Nagendran, J.6    Michelakis, E.D.7
  • 75
    • 84966389762 scopus 로고    scopus 로고
    • Modulators of right ventricular apoptosis and contractility in a rat model of pulmonary hypertension
    • Zungu-Edmondson M, Shults NV, Wong CM, Suzuki YJ. Modulators of right ventricular apoptosis and contractility in a rat model of pulmonary hypertension. Cardiovasc Res. 2016;110:30-39. doi: 10.1093/cvr/cvw014.
    • (2016) Cardiovasc Res , vol.110 , pp. 30-39
    • Zungu-Edmondson, M.1    Shults, N.V.2    Wong, C.M.3    Suzuki, Y.J.4
  • 76
    • 78149415338 scopus 로고    scopus 로고
    • Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure
    • Berl
    • Piao L, Marsboom G, Archer SL. Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure. J Mol Med (Berl). 2010;88:1011-1020. doi: 10.1007/s00109-010-0679-1.
    • (2010) J Mol Med ( , vol.88 , pp. 1011-1020
    • Piao, L.1    Marsboom, G.2    Archer, S.L.3
  • 79
    • 74549135132 scopus 로고    scopus 로고
    • Human cord blood stem cells enhance neonatal right ventricular function in an ovine model of right ventricular training
    • 593.e1.
    • Davies B, Elwood NJ, Li S, Cullinane F, Edwards GA, Newgreen DF, Brizard CP. Human cord blood stem cells enhance neonatal right ventricular function in an ovine model of right ventricular training. Ann Thorac Surg. 2010;89:585-593, 593.e1. doi: 10.1016/j.athoracsur.2009.10.035.
    • (2010) Ann Thorac Surg , vol.89 , pp. 585-593
    • Davies, B.1    Elwood, N.J.2    Li, S.3    Cullinane, F.4    Edwards, G.A.5    Newgreen, D.F.6    Brizard, C.P.7
  • 80
    • 79151471175 scopus 로고    scopus 로고
    • Paracrine mechanisms of stem cell reparative and regenerative actions in the heart
    • Mirotsou M, Jayawardena TM, Schmeckpeper J, Gnecchi M, Dzau VJ. Paracrine mechanisms of stem cell reparative and regenerative actions in the heart. J Mol Cell Cardiol. 2011;50:280-289. doi: 10.1016/j.yjmcc.2010.08.005.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 280-289
    • Mirotsou, M.1    Jayawardena, T.M.2    Schmeckpeper, J.3    Gnecchi, M.4    Dzau, V.J.5
  • 81
    • 84924165716 scopus 로고    scopus 로고
    • Intracoronary autologous cardiac progenitor cell transfer in patients with hypoplastic left heart syndrome: The TICAP prospective phase 1 controlled trial
    • Ishigami S, Ohtsuki S, Tarui S, et al. Intracoronary autologous cardiac progenitor cell transfer in patients with hypoplastic left heart syndrome: the TICAP prospective phase 1 controlled trial. Circ Res. 2015;116:653-664. doi: 10.1161/CIRCRESAHA.116.304671.
    • (2015) Circ Res , vol.116 , pp. 653-664
    • Ishigami, S.1    Ohtsuki, S.2    Tarui, S.3
  • 82
    • 85009178481 scopus 로고    scopus 로고
    • Intracoronary cardiac progenitor cells in singleventricle physiology: The Perseus (Cardiac progenitor cell infusion to treat univentricular heart disease) randomized phase 2 trial
    • Ishigami S, Ohtsuki S, Eitoku T, et al. Intracoronary cardiac progenitor cellsinsingleventriclephysiology:thePERSEUS(CardiacProgenitorCell Infusion to Treat Univentricular Heart Disease) randomized phase 2 trial. CircRes.2017;120:1162-1173.doi:10.1161/CIRCRESAHA.116.310253.
    • (2017) CircRes , vol.120 , pp. 1162-1173
    • Ishigami, S.1    Ohtsuki, S.2    Eitoku, T.3
  • 83
    • 84948714563 scopus 로고    scopus 로고
    • Transcoronary infusion of cardiac progenitor cells in hypoplastic left heart syndrome: Three-year follow-up of the transcoronary infusion of cardiac progenitor cells in patients with single-ventricle physiology (TICAP) trial
    • 1208.e1.
    • Tarui S, Ishigami S, Ousaka D, Kasahara S, Ohtsuki S, Sano S, Oh H. Transcoronary infusion of cardiac progenitor cells in hypoplastic left heart syndrome: three-year follow-up of the Transcoronary Infusion of Cardiac Progenitor Cells in Patients With Single-Ventricle Physiology (TICAP) trial. J Thorac Cardiovasc Surg. 2015;150:1198-1207, 1208.e1. doi: 10.1016/j.jtcvs.2015.06.076.
    • (2015) J Thorac Cardiovasc Surg , vol.150 , pp. 1198-1207
    • Tarui, S.1    Ishigami, S.2    Ousaka, D.3    Kasahara, S.4    Ohtsuki, S.5    Sano, S.6    Oh, H.7
  • 84
    • 85027421135 scopus 로고    scopus 로고
    • Study design and rationale for ELPIS: A phase I/IIb randomized pilot study of allogeneic human mesenchymal stem cell injection in patients with hypoplastic left heart syndrome
    • Kaushal S, Wehman B, Pietris N, et al. Study design and rationale for ELPIS: a phase I/IIb randomized pilot study of allogeneic human mesenchymal stem cell injection in patients with hypoplastic left heart syndrome. Am Heart J. 2017;192:48-56. doi: 10.1016/j.ahj.2017.06.009.
    • (2017) Am Heart J , vol.192 , pp. 48-56
    • Kaushal, S.1    Wehman, B.2    Pietris, N.3
  • 85
    • 84872498915 scopus 로고    scopus 로고
    • Cardiac stem cell therapy to modulate inflammation upon myocardial infarction
    • van den Akker F, Deddens JC, Doevendans PA, Sluijter JP. Cardiac stem cell therapy to modulate inflammation upon myocardial infarction. Biochim Biophys Acta. 2013;1830:2449-2458. doi: 10.1016/j.bbagen.2012.08.026.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 2449-2458
    • Van Den Akker, F.1    Deddens, J.C.2    Doevendans, P.A.3    Sluijter, J.P.4
  • 86
    • 79953903083 scopus 로고    scopus 로고
    • Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair
    • Loffredo FS, Steinhauser ML, Gannon J, Lee RT. Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair. Cell Stem Cell. 2011;8:389-398. doi: 10.1016/j.stem.2011.02.002.
    • (2011) Cell Stem Cell , vol.8 , pp. 389-398
    • Loffredo, F.S.1    Steinhauser, M.L.2    Gannon, J.3    Lee, R.T.4
  • 87
    • 84866458300 scopus 로고    scopus 로고
    • A strong regenerative ability of cardiac stem cells derived from neonatal hearts
    • Simpson DL, Mishra R, Sharma S, Goh SK, Deshmukh S, Kaushal S. A strong regenerative ability of cardiac stem cells derived from neonatal hearts. Circulation. 2012;126:S46-S53. doi: 10.1161/CIRCULATIONAHA. 111.084699.
    • (2012) Circulation , vol.126 , pp. S46-S53
    • Simpson, D.L.1    Mishra, R.2    Sharma, S.3    Goh, S.K.4    Deshmukh, S.5    Kaushal, S.6
  • 90
    • 84870877380 scopus 로고    scopus 로고
    • Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: The TIME randomized trial
    • Traverse JH, Henry TD, Pepine CJ, et al; Cardiovascular Cell Therapy Research Network (CCTRN). Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial. JAMA. 2012;308:2380-2389. doi: 10.1001/jama.2012.28726.
    • (2012) JAMA , vol.308 , pp. 2380-2389
    • Traverse, J.H.1    Henry, T.D.2    Pepine, C.J.3
  • 91
    • 81255208675 scopus 로고    scopus 로고
    • Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: The late TIME randomized trial
    • Traverse JH, Henry TD, Ellis SG, et al; Cardiovascular Cell Therapy ResearchNetwork. Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial. JAMA. 2011;306:2110-2119. doi: 10.1001/jama.2011.1670.
    • (2011) JAMA , vol.306 , pp. 2110-2119
    • Traverse, J.H.1    Henry, T.D.2    Ellis, S.G.3
  • 92
    • 84866391474 scopus 로고    scopus 로고
    • Cause, timing, and location of death in the single ventricle reconstruction trial
    • Ohye R, JV S, Eghtesady P, et al. Cause, timing, and location of death in the single ventricle reconstruction trial. J Thorac Cardiovasc Surg. 2012;144:907-914.
    • (2012) J Thorac Cardiovasc Surg , vol.144 , pp. 907-914
    • Ohye, R.1    Jv, S.2    Eghtesady, P.3
  • 93
    • 85027763639 scopus 로고    scopus 로고
    • Adult stem cell therapy and heart failure, 2000 to 2016: A systematic review
    • Nguyen PK, Rhee JW, Wu JC. Adult stem cell therapy and heart failure, 2000 to 2016: a systematic review. JAMA Cardiol. 2016;1:831-841. doi: 10.1001/jamacardio.2016.2225.
    • (2016) JAMA Cardiol , vol.1 , pp. 831-841
    • Nguyen, P.K.1    Rhee, J.W.2    Wu, J.C.3
  • 94
    • 67649658235 scopus 로고    scopus 로고
    • Cardiomyocyte renewal
    • Parmacek MS, Epstein JA. Cardiomyocyte renewal. N Engl J Med. 2009;361:86-88. doi: 10.1056/NEJMcibr0903347.
    • (2009) N Engl J Med , vol.361 , pp. 86-88
    • Parmacek, M.S.1    Epstein, J.A.2
  • 97
    • 84961291666 scopus 로고    scopus 로고
    • Regenerative therapy for hypoplastic left heart syndrome: First report of intraoperative intramyocardial injection of autologous umbilical-cord blood-derived cells
    • Burkhart HM, Qureshi MY, Peral SC, O'Leary PW, Olson TM, Cetta F, Nelson TJ; Wanek Program Clinical Pipeline Group. Regenerative therapy for hypoplastic left heart syndrome: first report of intraoperative intramyocardial injection of autologous umbilical-cord blood-derived cells. JThorac Cardiovasc Surg. 2015;149:e35-e37. doi: 10.1016/j.jtcvs.2014.10.093.
    • (2015) JThorac Cardiovasc Surg , vol.149 , pp. e35-e37
    • Burkhart, H.M.1    Qureshi, M.Y.2    Peral, S.C.3    O'Leary, P.W.4    Olson, T.M.5    Cetta, F.6    Nelson, T.J.7
  • 100
    • 33646269967 scopus 로고    scopus 로고
    • A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction
    • Freyman T, Polin G, Osman H, Crary J, Lu M, Cheng L, Palasis M, Wilensky RL. A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J. 2006;27:1114-1122. doi: 10.1093/eurheartj/ehi818.
    • (2006) Eur Heart J , vol.27 , pp. 1114-1122
    • Freyman, T.1    Polin, G.2    Osman, H.3    Crary, J.4    Lu, M.5    Cheng, L.6    Palasis, M.7    Wilensky, R.L.8
  • 101
    • 84994252323 scopus 로고    scopus 로고
    • Stem cell-derived exosomes, autophagy, extracellular matrix turnover, and miRNAs in cardiac regeneration during stem cell therapy
    • Prathipati P NS, Mishra PK. Stem cell-derived exosomes, autophagy, extracellular matrix turnover, and miRNAs in cardiac regeneration during stem cell therapy. Stem Cell Rev Rep. 2016;13:79-91.
    • (2016) Stem Cell Rev Rep , vol.13 , pp. 79-91
    • Prathipati, P.N.S.1    Mishra, P.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.