-
1
-
-
0032822390
-
Allergic rhinobronchitis: The asthma-allergic rhinitis link
-
Simons FE. Allergic rhinobronchitis: the asthma-allergic rhinitis link. J Allergy Clin Immunol 1999; 104: 534–540.
-
(1999)
J Allergy Clin Immunol
, vol.104
, pp. 534-540
-
-
Simons, F.E.1
-
2
-
-
0037841802
-
Rhinitis and asthma: Evidence for respiratory system integration
-
Togias A. Rhinitis and asthma: evidence for respiratory system integration. J Allergy Clin Immunol 2003; 111: 1171–1183.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1171-1183
-
-
Togias, A.1
-
3
-
-
40549093007
-
Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)
-
Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008; 63: Suppl. 86, 8–160.
-
(2008)
Allergy
, vol.63
, pp. 8-160
-
-
Bousquet, J.1
Khaltaev, N.2
Cruz, A.A.3
-
4
-
-
0032875421
-
Perennial rhinitis: An independent risk factor for asthma in nonatopic subjects: Results from the European Community Respiratory Health Survey
-
Leynaert B, Bousquet J, Neukirch C, et al. Perennial rhinitis: an independent risk factor for asthma in nonatopic subjects: results from the European Community Respiratory Health Survey. J Allergy Clin Immunol 1999; 104: 301–304.
-
(1999)
J Allergy Clin Immunol
, vol.104
, pp. 301-304
-
-
Leynaert, B.1
Bousquet, J.2
Neukirch, C.3
-
5
-
-
52049119046
-
Rhinitis and onset of asthma: A longitudinal population-based study
-
Shaaban R, Zureik M, Soussan D, et al. Rhinitis and onset of asthma: a longitudinal population-based study. Lancet 2008; 372: 1049–1057.
-
(2008)
Lancet
, vol.372
, pp. 1049-1057
-
-
Shaaban, R.1
Zureik, M.2
Soussan, D.3
-
6
-
-
53749097483
-
Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies
-
McDougall CM, Blaylock MG, Douglas JG, et al. Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies. Am J Respir Cell Mol Biol 2008; 39: 560–568.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 560-568
-
-
McDougall, C.M.1
Blaylock, M.G.2
Douglas, J.G.3
-
7
-
-
84954550847
-
Primary airway epithelial cell culture and asthma in children-lessons learnt and yet to come
-
McLellan K, Shields M, Power U, et al. Primary airway epithelial cell culture and asthma in children-lessons learnt and yet to come. Pediatr Pulmonol 2015; 50: 1393–1405.
-
(2015)
Pediatr Pulmonol
, vol.50
, pp. 1393-1405
-
-
McLellan, K.1
Shields, M.2
Power, U.3
-
8
-
-
35649028488
-
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
-
Woodruff PG, Boushey HA, Dolganov GM, et al. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci USA 2007; 104: 15858–15863.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15858-15863
-
-
Woodruff, P.G.1
Boushey, H.A.2
Dolganov, G.M.3
-
9
-
-
84860487629
-
Distinct epithelial gene expression phenotypes in childhood respiratory allergy
-
Giovannini-Chami L, Marcet B, Moreilhon C, et al. Distinct epithelial gene expression phenotypes in childhood respiratory allergy. Eur Respir J 2012; 39: 1197–1205.
-
(2012)
Eur Respir J
, vol.39
, pp. 1197-1205
-
-
Giovannini-Chami, L.1
Marcet, B.2
Moreilhon, C.3
-
10
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren J, Lemanske RF, Hanania NA, et al. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011; 365: 1088–1098.
-
(2011)
N Engl J Med
, vol.365
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
-
11
-
-
85010908346
-
Revisiting Type 2-high and Type 2-low airway inflammation in asthma: Current knowledge and therapeutic implications
-
Robinson D, Humbert M, Buhl R, et al. Revisiting Type 2-high and Type 2-low airway inflammation in asthma: current knowledge and therapeutic implications. Clin Exp Allergy 2017; 47: 161–175.
-
(2017)
Clin Exp Allergy
, vol.47
, pp. 161-175
-
-
Robinson, D.1
Humbert, M.2
Buhl, R.3
-
12
-
-
84964573673
-
2 agonist: A randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
-
2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial. Lancet 2016; 388: 31–44.
-
(2016)
Lancet
, vol.388
, pp. 31-44
-
-
Wenzel, S.1
Castro, M.2
Corren, J.3
-
13
-
-
84907424177
-
Mepolizumab treatment in patients with severe eosinophilic asthma
-
Ortega HG, Liu MC, Pavord ID, et al. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med 2014; 371: 1198–1207.
-
(2014)
N Engl J Med
, vol.371
, pp. 1198-1207
-
-
Ortega, H.G.1
Liu, M.C.2
Pavord, I.D.3
-
14
-
-
84907423833
-
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma
-
Bel EH, Wenzel SE, Thompson PJ, et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med 2014; 371: 1189–1197.
-
(2014)
N Engl J Med
, vol.371
, pp. 1189-1197
-
-
Bel, E.H.1
Wenzel, S.E.2
Thompson, P.J.3
-
15
-
-
84939795095
-
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
-
Choy DF, Hart KM, Borthwick LA, et al. TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma. Sci Transl Med 2015; 7: 301ra129.
-
(2015)
Sci Transl Med
, vol.7
, pp. 301ra129
-
-
Choy, D.F.1
Hart, K.M.2
Borthwick, L.A.3
-
16
-
-
85045238966
-
IFN-stimulated gene expression, type 2 inflammation, and endoplasmic reticulum stress in asthma
-
Bhakta NR, Christenson SA, Nerella S, et al. IFN-stimulated gene expression, type 2 inflammation, and endoplasmic reticulum stress in asthma. Am J Respir Crit Care Med 2018; 197: 313–324.
-
(2018)
Am J Respir Crit Care Med
, vol.197
, pp. 313-324
-
-
Bhakta, N.R.1
Christenson, S.A.2
Nerella, S.3
-
17
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
Woodruff PG, Modrek B, Choy DF, et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 2009; 180: 388–395.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
-
18
-
-
77956378655
-
Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision
-
Brozek JL, Bousquet J, Baena-Cagnani CE, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol 2010; 126: 466–476.
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 466-476
-
-
Brozek, J.L.1
Bousquet, J.2
Baena-Cagnani, C.E.3
-
20
-
-
36348929624
-
-
Bethesda, NHLBI, Date last accessed: September 17, 2018
-
National Heart, Lung, and Blood Institute (NHLBI). Expert panel report 3: guidelines for the diagnosis and management of asthma. Bethesda, NHLBI, 2007. www.nhlbi.nih.gov/files/docs/guidelines/asthgdln.pdf Date last accessed: September 17, 2018.
-
(2007)
Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma
-
-
-
21
-
-
34447307934
-
Mediante: A web-based microarray data manager
-
Le Brigand K, Barbry P. Mediante: a web-based microarray data manager. Bioinformatics 2007; 23: 1304–1306.
-
(2007)
Bioinformatics
, vol.23
, pp. 1304-1306
-
-
Le Brigand, K.1
Barbry, P.2
-
22
-
-
84870520781
-
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition
-
Alevy YG, Patel AC, Romero AG, et al. IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J Clin Invest 2012; 122: 4555–4568.
-
(2012)
J Clin Invest
, vol.122
, pp. 4555-4568
-
-
Alevy, Y.G.1
Patel, A.C.2
Romero, A.G.3
-
23
-
-
33846904740
-
IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production
-
Zhen G, Park SW, Nguyenvu LT, et al. IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production. Am J Respir Cell Mol Biol 2007; 36: 244–253.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 244-253
-
-
Zhen, G.1
Park, S.W.2
Nguyenvu, L.T.3
-
24
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004; 5: R80.
-
(2004)
Genome Biol
, vol.5
, pp. R80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
-
25
-
-
79251582522
-
Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways
-
Choy DF, Modrek B, Abbas AR, et al. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. J Immunol 2011; 186: 1861–1869.
-
(2011)
J Immunol
, vol.186
, pp. 1861-1869
-
-
Choy, D.F.1
Modrek, B.2
Abbas, A.R.3
-
26
-
-
77952012523
-
The link between allergic rhinitis and asthma: The united airways disease
-
Compalati E, Ridolo E, Passalacqua G, et al. The link between allergic rhinitis and asthma: the united airways disease. Expert Rev Clin Immunol 2010; 6: 413–423.
-
(2010)
Expert Rev Clin Immunol
, vol.6
, pp. 413-423
-
-
Compalati, E.1
Ridolo, E.2
Passalacqua, G.3
-
27
-
-
67649210683
-
In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects
-
Lopez-Souza N, Favoreto S, Wong H, et al. In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects. J Allergy Clin Immunol 2009; 123: 1384–1390.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 1384-1390
-
-
Lopez-Souza, N.1
Favoreto, S.2
Wong, H.3
-
28
-
-
0347302914
-
Allergic rhinitis: A disease remodeling the upper airways?
-
Bousquet J, Jacot W, Vignola AM, et al. Allergic rhinitis: a disease remodeling the upper airways? J Allergy Clin Immunol 2004; 113: 43–49.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 43-49
-
-
Bousquet, J.1
Jacot, W.2
Vignola, A.M.3
-
29
-
-
84857880134
-
Comparison of nasal and bronchial epithelial cells obtained from patients with COPD
-
Comer DM, Elborn JS, Ennis M. Comparison of nasal and bronchial epithelial cells obtained from patients with COPD. PLoS One 2012; 7: e32924.
-
(2012)
PLoS One
, vol.7
-
-
Comer, D.M.1
Elborn, J.S.2
Ennis, M.3
-
30
-
-
85014883674
-
A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED
-
Kuo CS, Pavlidis S, Loza M, et al. A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED. Am J Respir Crit Care Med 2017; 195: 443–455.
-
(2017)
Am J Respir Crit Care Med
, vol.195
, pp. 443-455
-
-
Kuo, C.S.1
Pavlidis, S.2
Loza, M.3
-
31
-
-
85010877252
-
The current and future role of biomarkers in type 2 cytokine-mediated asthma management
-
Pavord ID, Afzalnia S, Menzies-Gow A, et al. The current and future role of biomarkers in type 2 cytokine-mediated asthma management. Clin Exp Allergy 2017; 47: 148–160.
-
(2017)
Clin Exp Allergy
, vol.47
, pp. 148-160
-
-
Pavord, I.D.1
Afzalnia, S.2
Menzies-Gow, A.3
-
32
-
-
84989808988
-
Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): Replicate, phase 3, randomised, double-blind, placebo-controlled trials
-
Hanania NA, Korenblat P, Chapman KR, et al. Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials. Lancet Respir Med 2016; 4: 781–796.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 781-796
-
-
Hanania, N.A.1
Korenblat, P.2
Chapman, K.R.3
-
33
-
-
84895064176
-
Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma
-
Peters MC, Mekonnen ZK, Yuan S, et al. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol 2014; 133: 388–394.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 388-394
-
-
Peters, M.C.1
Mekonnen, Z.K.2
Yuan, S.3
-
34
-
-
85013420544
-
T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED
-
Kuo CS, Pavlidis S, Loza M, et al. T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED. Eur Respir J 2017; 49: 1602135.
-
(2017)
Eur Respir J
, vol.49
, pp. 1602135
-
-
Kuo, C.S.1
Pavlidis, S.2
Loza, M.3
-
35
-
-
84896701857
-
Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease
-
Poole A, Urbanek C, Eng C, et al. Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease. J Allergy Clin Immunol 2014; 133: 670–678.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 670-678
-
-
Poole, A.1
Urbanek, C.2
Eng, C.3
-
36
-
-
79957895825
-
Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway
-
Marcet B, Chevalier B, Luxardi G, et al. Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway. Nat Cell Biol 2011; 13: 693–699.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 693-699
-
-
Marcet, B.1
Chevalier, B.2
Luxardi, G.3
-
37
-
-
85012921681
-
Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome
-
Wesolowska-Andersen A, Everman JL, Davidson R, et al. Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome. Genome Biol 2017; 18: 12.
-
(2017)
Genome Biol
, vol.18
, pp. 12
-
-
Wesolowska-Andersen, A.1
Everman, J.L.2
Davidson, R.3
-
39
-
-
0038240988
-
Mucosal and systemic inflammatory changes in allergic rhinitis and asthma: A comparison between upper and lower airways
-
Braunstahl GJ, Fokkens WJ, Overbeek SE, et al. Mucosal and systemic inflammatory changes in allergic rhinitis and asthma: a comparison between upper and lower airways. Clin Exp Allergy 2003; 33: 579–587.
-
(2003)
Clin Exp Allergy
, vol.33
, pp. 579-587
-
-
Braunstahl, G.J.1
Fokkens, W.J.2
Overbeek, S.E.3
-
40
-
-
85031856879
-
Viral infections in allergy and immunology: How allergic inflammation influences viral infections and illness
-
Edwards MR, Strong K, Cameron A, et al. Viral infections in allergy and immunology: how allergic inflammation influences viral infections and illness. J Allergy Clin Immunol 2017; 140: 909–920.
-
(2017)
J Allergy Clin Immunol
, vol.140
, pp. 909-920
-
-
Edwards, M.R.1
Strong, K.2
Cameron, A.3
-
41
-
-
85014370057
-
Accurately measuring and modeling Th2 and Th17 endotypes in severe asthma
-
Hart KM, Choy DF, Bradding P, et al. Accurately measuring and modeling Th2 and Th17 endotypes in severe asthma. Ann Transl Med 2017; 5: 91.
-
(2017)
Ann Transl Med
, vol.5
, pp. 91
-
-
Hart, K.M.1
Choy, D.F.2
Bradding, P.3
|