IFN-stimulated gene expression, type 2 inflammation, and endoplasmic reticulum stress in asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 197, Issue 3, 2018, Pages 313-324

  Bhakta, Nirav R ^a   Christenson, Stephanie A ^a   Nerella, Srilaxmi ^a   Solberg, Owen D ^a   Nguyen, Christine P ^a   Choy, David F ^f   Jung, Kyle L ^a   Garudadri, Suresh ^a   Bonser, Luke R ^b,c   Pollack, Joshua L ^c   Zlock, Lorna T ^d   Erle, David J ^b,c   Langelier, Charles ^e   Derisi, Joseph L ^g   Arron, Joseph R ^f   Fahy, John V ^a,b   Woodruff, Prescott G ^b,e  

^a Division of Pulmonary   (United States)

^b Cardiovascular Research Institute   (United States)

^c Lung Biology Center   (United States)

^d San Francisco ^*  (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f GENENTECH INC   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Asthma; Blood gene expression; Endoplasmic reticulum stress; IFNs; Type 2 inflammation

Indexed keywords

ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; AGT PROTEIN; ALPHA INTERFERON; BETA INTERFERON; BETA1 INTERFERON; BRONCHODILATING AGENT; CHLORIDE CHANNEL ACCESSORY 1; CORTICOSTEROID; CYTOKINE; HRAS PROTEIN; INITIATION FACTOR 4E; INTERFERON; INTERFERON ALPHA AND BETA RECEPTOR SUBUNIT 2; INTERFERON LAMBDA; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 13; INTERLEUKIN 5; MYC PROTEIN; MYCN PROTEIN; PAF1 PROTEIN; PRL PROTEIN; PROTEIN; PROTEIN P53; RNA; SERPIN FAMILY B MEMBER 2; STAT1 PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; VEGFA PROTEIN; X BOX BINDING PROTEIN 1; AUTACOID; INTERFERON REGULATORY FACTOR 3;

ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENDOPLASMIC RETICULUM STRESS; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION; HUMAN; INFLAMMATION; LUNG FUNCTION; MALE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RNA SEQUENCE; TYPE 2 INFLAMMATION; VIRUS GENOME; CASE CONTROL STUDY; ENDOPLASMIC RETICULUM; EOSINOPHIL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; OXIDATIVE STRESS; PATHOPHYSIOLOGY; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

ADULT; ASTHMA; CASE-CONTROL STUDIES; ENDOPLASMIC RETICULUM; EOSINOPHILS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; INTERFERON REGULATORY FACTOR-3; MALE; MIDDLE AGED; OXIDATIVE STRESS; REFERENCE VALUES; RNA; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 85045238966     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201706-1070OC     Document Type: Article

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