Structural and biochemical characterization of endoribonuclease nsp15 encoded by middle east respiratory syndrome coronavirus

Journal of Virology

Volumn 92, Issue 22, 2018, Pages

  Zhang, Lianqi ^a   Li, Lei ^b   Yan, Liming ^a   Ming, Zhenhua ^c   Jia, Zhihui ^a   Lou, Zhiyong ^a   Rao, Zihe ^a,d,e  

^a Tsinghua University   (China)

^b SICHUAN UNIVERSITY   (China)

^c GUANGXI UNIVERSITY   (China)

^d INSTITUTE OF BIOPHYSICS   (China)

^e NANKAI UNIVERSITY   (China)

Author keywords

Crystal structure; Endoribonuclease; MERS CoV; Oligomerization

Indexed keywords

ALANINE; ASPARTIC ACID; NONSTRUCTURAL PROTEIN 15; NONSTRUCTURAL PROTEIN 7; NONSTRUCTURAL PROTEIN 8; RIBONUCLEASE; SERINE; UNCLASSIFIED DRUG; VIRAL PROTEIN; VIRUS RNA; NONSTRUCTURAL PROTEIN, CORONAVIRUS; RNA BINDING PROTEIN; RNA DIRECTED RNA POLYMERASE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; HEXAMERIZATION; IN VITRO STUDY; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RNA BINDING; VIRUS MUTATION; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; HUMAN; PROTEIN MULTIMERIZATION; SEQUENCE ALIGNMENT; VIRUS REPLICATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ENDORIBONUCLEASES; HUMANS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; PROTEIN MULTIMERIZATION; RNA REPLICASE; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 85055613139     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00893-18     Document Type: Article

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