Site-directed mutagenesis of the nidovirus replicative endoribonuclease NendoU exerts pleiotropic effects on the arterivirus life cycle

Journal of Virology

Volumn 80, Issue 4, 2006, Pages 1653-1661

  Posthuma, Clara C ^a   Nedialkova, Danny D ^a   Zevenhoven Dobbe, Jessika C ^a   Blokhuis, Jeroen H ^a   Gorbalenya, Alexander E ^a   Snijder, Eric J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN NENDOU; PROTEIN NSP11; PROTEIN XENDOU; RIBONUCLEASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

AMINO ACID SEQUENCE; ARTERIVIRUS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CORONAVIRUS; ENZYME ACTIVITY; EQUINE VIRAL ARTERITIS VIRUS; LETHALITY; LIFE CYCLE; NIDOVIRALES; NIDOVIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGENY; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; RNA SYNTHESIS; RNA VIRUS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; VIRUS GENOME; VIRUS MUTANT; VIRUS REPLICATION; VIRUS STRAIN; XENOPUS LAEVIS;

AMINO ACID SUBSTITUTION; ANIMALS; ARTERITIS VIRUS, EQUINE; ARTERIVIRIDAE; CELL LINE; CORONAVIRIDAE; CRICETINAE; ENDORIBONUCLEASES; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PLAQUE ASSAY; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRUS REPLICATION;

ARTERIVIRUS; CORONAVIRUS; EQUINE ARTERITIS VIRUS; NIDOVIRALES; RNA VIRUSES; XENOPUS LAEVIS;

EID: 32444450251     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.4.1653-1661.2006     Document Type: Article

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