Impact of DNA methylation on health and disease

DNA Methylation: Approaches, Methods, and Applications

Volumn , Issue , 2004, Pages 1-10

  Esteller, Manel ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85055504901     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9780203487013     Document Type: Chapter

References (35)

1. Jenuwein T, Allis CD, Translating the histone code. Science, 293, 1074-1080, 2001.
2. Esteller M, Relevance of DNA methylation in the management of cancer. Lancet Oncol., 4, 351-358, 2003.
3. Esteller M, Corn PG, Baylin SB, Herman JG, A gene hypermethylation profile of human cancer. Cancer Res., 61, 3225-3229, 2001.
4. Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O’Dorisio MS, Held WA, Cavenee WK, Plass C, Aberrant CpG-island methylation has nonrandom and tumour-type-specific patterns. Nat. Genet., 24, 132-138, 2001.
5. Jones, PA, Laird, PW, Cancer epigenetics comes of age. Nat. Genet., 21, 163-167, 1999.
6. Esteller M, CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene, 21, 5427-5440, 2002.
7. Herman JG, Baylin, SB, Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med., 349, 2042-2054, 2003.
8. Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V, Baylin SB, Herman JG, Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N. Engl. J. Med., 343, 1350-1354, 2000.
9. Esteller M, Gaidano G, Goodman SN, Zagonel V, Capello D, Botto B, Rossi D, Gloghini A, Vitolo U, Carbone A, Baylin SB, Herman JG, Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J. Natl. Cancer Inst., 94, 26-32, 2002.
10. Esteller M, Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. Oncogene, 23, 1-8, 2004.
11. Villar-Garea A, Esteller M, DNA demethylating agents and chromatin-remodelling drugs: which, how and why? Curr. Drug Metab., 4, 11-31, 2003.
12. Paz MF, Fraga MF, Avila S, Guo M, Pollan M, Herman JG, Esteller M, A systematic profile of DNA methylation in human cancer cell lines. Cancer Res., 63, 1114-1121, 2003.
13. Esteller M, Sanchez-Cespedes M, Rosell R, Sidransky D, Baylin SB, Herman JG, Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small-cell lung cancer patients. Cancer Res., 59, 67-70, 1999.
14. Ehrlich M, DNA hypomethylation and cancer. In:DNA alterations in cancer: genetic and epigenetic changes, ed.Melanie Ehrlich, Eaton Publishing, Natick, MA, 273-291, 2000.
15. Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedenfalk I, Godwin AK, Trojan J, Vaurs-Barriere C, Bignon YJ, Ramus S, Benitez J, Caldes T, Akiyama Y, Yuasa Y, Launonen V, Canal MJ, Rodriguez R, Capella G, Peinado MA, Borg A, Aaltonen LA, Ponder BA, Baylin SB, Herman JG, DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum. Mol. Genet., 10, 3001-3007, 2001.
16. Xu GL, Bestor TH, Bourc’his D, et al., Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature, 1999; 402. 187-191, 1999.
17. Yoder JA, Walsh CP, Bestor TH, Cytosine methylation and the ecology of intragenomic parasites. Trends Genet., 13, 335-340, 1997.
18. Plass C, Soloway PD, DNA methylation, imprinting and cancer. Eur. J. Hum. Genet., 10, 6-16, 2002.
19. Okano M, Bell DW, Haber DA, Li E, DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell., 99, 247-257, 1999.
20. Gibbons RJ, McDowell TL, Raman S, O’Rourke DM, Garrick D, Ayyub H, Higgs DR, Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat. Genet., 24, 368-371, 2000.
21. Richardson B, Scheinbart L, Strahler J, Gross L, Hanash S, Johnson M, Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum., 33, 1665-1673, 1990.
22. Corvetta A, Della Bitta R, Luchetti MM, Pomponio G, 5-Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmune rheumatic diseases. J. Chromatogr. 566, 481-491, 1991.
23. Kominato Y, Hata Y, Takizawa H, Tsuchiya T, Tsukada J, Yamamoto F, Expression of human histo-blood group ABO genes is dependent upon DNA methylation of the promoter region. J. Biol. Chem., 274, 37240-37250, 1999.
24. Nie Y, Yang G, Song Y, Zhao X, So C, Liao J, Wang LD, Yang CS, DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. Carcinogenesis, 22, 1615-1623, 2001.
25. De Smet C, Lurquin C, Lethe B, Martelange V, Boon T, DNA methylation is the primary silencing mechanism for a set of germ line-and tumor-specific genes with a CpG-rich promoter. Mol. Cell Biol., 19, 7327-7335, 1999.
26. Shahbazian MD, Zoghbi HY, Rett syndrome and MeCP2: linking epigenetics and neuronal function. Am. J. Hum. Genet., 71, 1259-1272, 2002.
27. Ballestar E, Paz MF, Valle L, Wei S, Fraga MF, Espada J, Cigudosa JC, Huang TH, Esteller M, Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J., 22, 6335-6345, 2003.
28. Post WS, Goldschmidt-Clermont PJ, Wilhide CC, Heldman AW, Sussman MS, Ouyang P, Milliken EE, Issa JP, Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system. Cardiovasc Res., 43, 985-991, 1999.
29. Paz MF, Avila S, Fraga MF, Pollan M, Capella G, Peinado MA, Sanchez-Cespedes M, Herman JG, Esteller M, Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. Cancer Res., 62, 4519-4524, 2002.
30. Eskes TK, Neural tube defects, vitamins and homocysteine. Eur. J. Pediatr., 157, Suppl. 2: S139-141, 1998.
31. Shi W, Zakhartchenko V, Wolf E, Epigenetic reprogramming in mammalian nuclear transfer. Differentiation, 71, 91-113, 2003.
32. Fraga MF, Esteller M, DNA methylation: a profile of methods and applications. Biotechniques, 33, 632-649, 2002.
33. Paz MF, Wei S, Cigudosa JC, Rodriguez-Perales S, Peinado MA, Huang TH, Esteller M, Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. Hum. Mol. Genet., 12, 2209-2219, 2003.
34. Piyathilake CJ, Johanning GL, Frost AR, Whiteside MA, Manne U, Grizzle WE, Heimburger DC, Niveleau A, Immunohistochemical evaluation of global DNA methylation:comparison with in vitro radiolabeled methyl incorporation assay. Biotech. Histochem., 75, 251-258, 2000.
35. Fraga MF, Uriol E, Borja Diego L, Berdasco M, Esteller M, Canal MJ, Rodriguez R, High-performance capillary electrophoretic method for the quantification of 5-methyl 2′ -deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues. Electrophoresis, 23, 1677-1681, 2002.