Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus

Cell Reports

Volumn 25, Issue 2, 2018, Pages 312-320.e7

  Krüger, Nadine ^a   Sauder, Christian ^b   Hüttl, Sarah ^a   Papies, Jan ^c   Voigt, Kathleen ^a   Herrler, Georg ^a   Hardes, Kornelia ^d   Steinmetzer, Torsten ^d   Örvell, Claes ^e   Drexler, Jan Felix ^c   Drosten, Christian ^c   Rubin, Steven ^b   Müller, Marcel Alexander ^c   Hoffmann, Markus ^f  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

^e KAROLINSKA INSTITUTE   (Sweden)

^f GERMAN PRIMATE CENTER   (Germany)

Author keywords

bat derived viruses; immune evasion; mumps virus; reverse genetics; viral entry; zoonosis

Indexed keywords

HN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; SIALIC ACID; TUMOR NECROSIS FACTOR; VIRUS ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; EMBRYO; FEMALE; HUMAN; HUMAN CELL; IMMUNE EVASION; IN VITRO STUDY; IN VIVO STUDY; MUMPS VIRUS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN TRANSPORT; RAT; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS NEUTRALIZATION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BAT; IMMUNOLOGY; LEWIS RAT; MUMPS; PATHOGENICITY; PATHOLOGY; TOXICITY AND INTOXICATION; VIROLOGY;

ANIMALS; CHIROPTERA; FEMALE; HUMANS; IMMUNE EVASION; MUMPS; MUMPS VIRUS; NEUROTOXICITY SYNDROMES; RATS; RATS, INBRED LEW; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 85054147456     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2018.09.018     Document Type: Article

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