T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

Nature Chemical Biology

Volumn 14, Issue 10, 2018, Pages 934-942

  Riley, Timothy P ^a   Hellman, Lance M ^a   Gee, Marvin H ^b   Mendoza, Juan L ^b   Alonso, Jesus A ^b   Foley, Kendra C ^c   Nishimura, Michael I ^c   Vander Kooi, Craig W ^d   Garcia, K Christopher ^b   Baker, Brian M ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LOYOLA UNIVERSITY HEALTH SYSTEM   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DMF5 PROTEIN; HLA A2 ANTIGEN; MELAN A; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; ANTIGEN; EPITOPE; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; MHC BINDING PEPTIDE; OLIGOPEPTIDE; PROTEIN BINDING;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL SPECIFICITY; CONFORMATIONAL TRANSITION; CROSS REACTION; CRYSTAL STRUCTURE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR MIMICRY; MOLECULAR RECOGNITION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; AUTOIMMUNITY; CHEMISTRY; HUMAN; KINETICS; PROTEIN DOMAIN; RETROVIRIDAE; SURFACE PLASMON RESONANCE; T LYMPHOCYTE; X RAY CRYSTALLOGRAPHY;

ANTIGENS; AUTOIMMUNITY; CROSS REACTIONS; CRYSTALLOGRAPHY, X-RAY; EPITOPES; HUMANS; KINETICS; LIGANDS; MOLECULAR MIMICRY; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN DOMAINS; RECEPTORS, ANTIGEN, T-CELL; RETROVIRIDAE; SURFACE PLASMON RESONANCE; T-LYMPHOCYTES;

EID: 85053424465     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/s41589-018-0130-4     Document Type: Article

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