Circular dichroism determination of class I MHC-peptide equilibrium dissociation constants

Protein Science

Volumn 6, Issue 8, 1997, Pages 1771-1773

  Morgan, Chantal S ^a   Holton, James M ^b,c   Olafson, Barry D ^b   Bjorkman, Pamela J ^b   Mayo, Stephen L ^b  

^a MC 147 75 ^*  (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Circular dichroism; Class I MHC; Dissociation constant

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE;

ARTICLE; CIRCULAR DICHROISM; DISSOCIATION CONSTANT; EQUILIBRIUM CONSTANT; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

EID: 0030762022     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560060819     Document Type: Article

References (12)

1. Bjorkman PJ, Parham P. 1990. Structure, function, and diversity of class I major histocompatibility complex molecules. Annu Rev Biochem 59:253-288.
2. Bouvier M, Wiley DC. 1994. Importance of peptide amino and carboxy termini to the stability of MHC Class I molecules. Science 265:398-402.
3. Fahnestock ML, Johnson JL, Feldman RMR, Neveu JM, Lane WS, Bjorkman PJ. 1995. The MHC Class I homolog encoded by human cytomegalovirus binds endogenous peptides. Immunity 3:583-590.
4. Fahnestock ML, Johnson JL, Feldman RMR, Tsomides TJ, Mayer J, Narhi LO, Bjorkman PJ. 1994. Effects of peptide length and composition on binding to an empty Class I MHC heterodimer. Biochemistry 33:8149-8158.
5. Fahnestock ML, Tamir I, Narhi L, Bjorkman PJ. 1992. Thermal stability comparison of purified empty and peptide-filled forms of a Class I MHC molecule. Science 255:1658-1662.
6. b. Science 257:919-927.
7. Ljunggren H, Stam N, Ohlen C, Neefjes J, Hoglund P, Heemels M, Bastin J, Schumacher T, Townsend A, Karre K, Ploegh H. 1990. Empty MHC Class I molecules come out in the cold. Nature 346:476-480.
8. d antigens on the surface of these cells. Transplantation 34:113-120.
9. Parham P, Androlewicz M, Holmes N, Rothenberg B. 1983. Arginine-45 is a major part of the antigenic determinant of human beta2-microglobulin recognized by mouse monoclonal-antibody BBM.1. J Biol Chem 258:6179-6186.
10. Parker KC, DiBrino M, Hull L, Coligan JE. 1992. The β2-Microglobulin dissociation rate is an accurate measure of the stability of MHC Class I heterotrimers and depends on which peptide is bound. J Immunol 149:1896-1904.
11. Schumacher TMM, Heemels M, Neefjes J, Kast W, Melief C, Ploegh H. 1990. Direct binding of peptide to empty MHC Class I molecules on intact cells and in vitro. Cell 62:563-567.
12. Townsend A, Elliot T, Cerundolo V, Foster L, Barber B, Tse A. 1990. Assembly of MHC Class I molecules analyzed in vitro. Cell 62:285-295.