Spreading ischemia after aneurysmal subarachnoid hemorrhage

Acta Neurochirurgica, Supplementum

Volumn 115, Issue , 2013, Pages 125-129

  Dreier, Jens P ^a   Drenckhahn, Christoph ^a   Woitzik, Johannes ^a   Major, Sebastian ^a   Offenhauser, Nikolas ^a   Weber Carstens, Steffen ^a   Wolf, Stefan ^a   Strong, Anthony J ^b   Vajkoczy, Peter ^a   Hartings, Jed A ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Aneurysmal subarachnoid hemorrhage; Delayed cerebral ischemia; Spreading depression

Indexed keywords

NITRIC OXIDE;

BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CALCIUM TRANSPORT; CONFERENCE PAPER; DIRECT CURRENT; ELECTROCORTICOGRAPHY; HUMAN; HYPOXEMIA; MICROVASCULATURE; NERVE CELL MEMBRANE STEADY POTENTIAL; RISK FACTOR; SPREADING DEPOLARIZATION; SUBARACHNOID HEMORRHAGE; TRAUMATIC BRAIN INJURY;

EID: 85052610229     PISSN: 00651419     EISSN: 00016268     Source Type: Book Series    
DOI: 10.1007/978-3-7091-1192-5_26     Document Type: Conference Paper

References (42)

1. Attwell D, Iadecola C (2002) The neural basis of functional brain imaging signals. Trends Neurosci 25:621-6255
2. Bosche B, Graf R, Ernestus RI, Dohmen C, Reithmeier T, Brinker G, Strong AJ, Dreier JP, Woitzik J (2010) Recurrent spreading depolarizations after SAH decrease oxygen availability in human cerebral cortex. Ann Neurol 67:607-6177
3. Canals S, Makarova I, Lopez-Aguado L, Largo C, Ibarz JM, Herreras O (2005) Longitudinal depolarization gradients along the somatodendritic axis of CA1 pyramidal cells: A novel feature of spreading depression. J Neurophysiol 94:943-9511
4. Dijkhuizen RM, Beekwilder JP, van der Worp HB, Berkelbach van der Sprenkel JW, Tulleken KA, Nicolay K (1999) Correlation between tissue depolarizations and damage in focal ischemic rat brain. Brain Res 840:194-2055
5. Dohmen C, Sakoitz OW, Fabricius M, Bosche B, Reithmeier T, Ernestus RI, Brinker G, Dreier JP, Woitzik J, Strong AJ, Graf R (2008) Spreading depolarizations occur in human ischemic stroke with high incidence. Ann Neurol 63:720-7288
6. Dreier JP (2011) The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat Med 17:439-4477
7. Dreier JP, Ebert N, Priller J, Megow D, Lindauer U, Klee R, Reuter U, Imai Y, Einhaupl KM, Victorov I, Dirnagl U (2000) Products of hemolysis in the subarachnoid space inducing spreading ischemia in the cortex and focal necrosis in rats: A model for delayed ischemic neurological de fi cits after subarachnoid hemorrhage? J Neurosurg 93:658-6666
8. Dreier JP, Kleeberg J, Alam M, Major S, Kohl-Bareis M, Petzold GC, Victorov I, Dirnagl U, Obrenovitch TP, Priller J (2007) Endothelin-1-induced spreading depression in rats is associated with a microarea of selective neuronal necrosis. Exp Biol Med (Maywood) 232:204-2133
9. Dreier JP, Kleeberg J, Petzold G, Priller J, Windmuller O, Orzechowski HD, Lindauer U, Heinemann U, Einhaupl KM, Dirnagl U (2002) Endothelin-1 potently induces Leao's cortical spreading depression in vivo in the rat: A model for an endothelial trigger of migrainous aura? Brain 125:102-1122
10. Dreier JP, Korner K, Ebert N, Gorner A, Rubin I, Back T, Lindauer U, Wolf T, Villringer A, Einhaupl KM, Lauritzen M, Dirnagl U (1998) Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space. J Cereb Blood Flow Metab 18:978-9900
11. Dreier JP, Major S, Manning A, Woitzik J, Drenckhahn C, Steinbrink J, Tolias C, Oliveira-Ferreira AI, Fabricius M, Hartings JA, Vajkoczy P, Lauritzen M, Dirnagl U, Bohner G, Strong AJ (2009) Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid hemorrhage. Brain 132:1866-18811
12. Dreier JP, Major S, Pannek HW, Woitzik J, Scheel M, Wiesenthal D, Martus P, Winkler M, Hartings JA, Fabricius M, Speckmann EJ, Gorji A (2011) Spreading convulsions, spreading depolarization, and epileptogenesis in human cerebral cortex. Brain 35:259-2755
13. Dreier JP, Woitzik J, Fabricius M, Bhatia R, Major S, Drenckhahn C, Lehmann TN, Sarrafzadeh A, Willumsen L, Hartings JA, Sakowitz OW, Seemann JH, Thieme A, Lauritzen M, Strong AJ (2006) Delayed ischaemic neurological de fi cits after subarachnoid hemorrhage are associated with clusters of spreading depolarizations. Brain 129:3224-32377
14. Fabricius M, Fuhr S, Bhatia R, Boutelle M, Hashemi P, Strong AJ, Lauritzen M (2006) Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex. Brain 129:778-7900
15. Farkas E, Bari F, Obrenovitch TP (2010) Multi-modal imaging of anoxic depolarization and hemodynamic changes induced by cardiac arrest in the rat cerebral cortex. Neuroimage 51:734-7422
16. Fox MD, Raichle ME (2007) Spontaneous fl uctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 8:700-7111
17. Hartings JA, Bullock MR, Okonkwo DO, Murray LS, Murray GD, Fabricius M, Maas AIR, Woitzik J, Sakowitz OW, Mathern B, Roozenbeek B, Lingsma H, Dreier JP, Puccio AM, Shutter LA, Pahl C, Strong AJ (2011) Spreading depolarisations and outcome after traumatic brain injury: A prospective observational study. Lancet Neurol 10:1058-10644
18. Hartings JA, Rolli ML, Lu XC, Tortella FC (2003) Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: Relation to infarct growth and neuroprotection. J Neurosci 23:11602-116100
19. Hartings JA, Watanabe T, Bullock MR, Okonkwo DO, Fabricius M, Woitzik J, Dreier JP, Puccio A, Shutter LA, Pahl C, Strong AJ (2011) Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma. Brain 134:1529-15400
20. Hossmann KA (1994) Viability thresholds and the penumbra of focal ischemia. Ann Neurol 36:557-5655
21. Kager H, Wadman WJ, Somjen GG (2002) Conditions for the triggering of spreading depression studied with computer simulations. J Neurophysiol 88:2700-27122
22. Koehler RC, Roman RJ, Harder DR (2009) Astrocytes and the regulation of cerebral blood fl ow. Trends Neurosci 32:160-1699
23. Kraig RP, Nicholson C (1978) Extracellular ionic variations during spreading depression. Neuroscience 3:1045-10599
24. Lauritzen M (1994) Pathophysiology of the migraine aura. The spreading depression theory. Brain 117(Pt 1):199-2100
25. Lauritzen M, Hansen AJ, Kronborg D, Wieloch T (1990) Cortical spreading depression is associated with arachidonic acid accumulation and preservation of energy charge. J Cereb Blood Flow Metab 10:115-1222
26. Leão AAP (1944) Spreading depression of activity in the cerebral cortex. J Neurophysiol 7:359-3900
27. Mies G, Iijima T, Hossmann KA (1993) Correlation between periinfarct DC shifts and ischaemic neuronal damage in rat. Neuroreport 4:709-7111
28. Nakamura H, Strong AJ, Dohmen C, Sakowitz OW, Vollmar S, Sue M, Kracht L, Hashemi P, Bhatia R, Yoshimine T, Dreier JP, Dunn AK, Graf R (2010) Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions. Brain 133:1994-20066
29. Nedergaard M, Hansen AJ (1988) Spreading depression is not associated with neuronal injury in the normal brain. Brain Res 449:395-3988
30. Nozari A, Dilekoz E, Sukhotinsky I, Stein T, Eikermann-Haerter K, Liu C, Wang Y, Frosch MP, Waeber C, Ayata C, Moskowitz MA (2010) Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol 67:221-2299
31. Oliveira-Ferreira AI, Milakara D, Alam M, Jorks D, Major S, Hartings JA, Lückl J, Martus P, Graf R, Dohmen C, Bohner G, Woitzik J, Dreier JP (2010) Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression. J Cereb Blood Flow Metab 30:1504-15199
32. Piilgaard H, Lauritzen M (2009) Persistent increase in oxygen consumption and impaired neurovascular coupling after spreading depression in rat neocortex. J Cereb Blood Flow Metab 29:1517-15277
33. Rossi DJ, Oshima T, Attwell D (2000) Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403: 316-321
34. Saito R, Graf R, Hubel K, Fujita T, Rosner G, Heiss WD (1997) Reduction of infarct volume by halothane: Effect on cerebral blood fl ow or perifocal spreading depression-like depolarizations. J Cereb Blood Flow Metab 17:857-8644
35. Shin HK, Dunn AK, Jones PB, Boas DA, Moskowitz MA, Ayata C (2006) Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab 26:1018-10300
36. Somjen GG (2004) Ions in the brain. Oxford University Press, Oxford
37. Strong AJ, Anderson PJ, Watts HR, Virley DJ, Lloyd A, Irving EA, Nagafuji T, Ninomiya M, Nakamura H, Dunn AK, Graf R (2007) Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex. Brain 130:995-10088
38. Strong AJ, Fabricius M, Boutelle MG, Hibbins SJ, Hopwood SE, Jones R, Parkin MC, Lauritzen M (2002) Spreading and synchronous depressions of cortical activity in acutely injured human brain. Stroke 33:2738-27433
39. Sukhotinsky I, Yaseen MA, Sakadzic S, Ruvinskaya S, Sims JR, Boas DA, Moskowitz MA, Ayata C (2010) Perfusion pressuredependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. J Cereb Blood Flow Metab 30:1168-11777
40. Takano T, Tian GF, Peng W, Lou N, Lovatt D, Hansen AJ, Kasischke KA, Nedergaard M (2007) Cortical spreading depression causes and coincides with tissue hypoxia. Nat Neurosci 10:754-7622
41. Windmuller O, Lindauer U, Foddis M, Einhaupl KM, Dirnagl U, Heinemann U, Dreier JP (2005) Ion changes in spreading ischaemia induce rat middle cerebral artery constriction in the absence of NO. Brain 128:2042-20511
42. Woitzik J, Dreier JP, Hecht N, Fiss I, Sandow N, Major S, Winkler MKL, Dahlem YA, Manville J, Diepers M, Muench E, Kasuya H, Schmiedek P, Vajkoczy P (2012) Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage. J Cereb Blood Flow Metab 32:203-2122