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Volumn 9, Issue 1, 2018, Pages

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

(124)  Ji, Xuemei a   Bossé, Yohan b,c   Landi, Maria Teresa d   Gui, Jiang a   Xiao, Xiangjun a   Qian, David a   Joubert, Philippe c   Lamontagne, Maxime c   Li, Yafang a   Gorlov, Ivan a   de Biasi, Mariella e,f   Han, Younghun a   Gorlova, Olga a   Hung, Rayjean J g   Wu, Xifeng h   McKay, James i   Zong, Xuchen g   Carreras Torres, Robert i   Christiani, David C j,k   Caporaso, Neil d   more..


Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CHROMOSOME; ETIOLOGY; GENETIC ANALYSIS; IDENTIFICATION METHOD; LIGAND; PROTEIN;

EID: 85051632965     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-05074-y     Document Type: Article
Times cited : (67)

References (65)
  • 1
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • PID: 21685461
    • Siegel, R., Ward, E., Brawley, O. & Jemal, A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J. Clin. 61, 212–236 (2011)
    • (2011) CA Cancer J. Clin. , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 2
    • 42649091460 scopus 로고    scopus 로고
    • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
    • PID: 18385676
    • Amos, C. I. et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat. Genet. 40, 616–622 (2008)
    • (2008) Nat. Genet. , vol.40 , pp. 616-622
    • Amos, C.I.1
  • 3
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • PID: 18385738
    • Hung, R. J. et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452, 633–637 (2008)
    • (2008) Nature , vol.452 , pp. 633-637
    • Hung, R.J.1
  • 4
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • PID: 18385739
    • Thorgeirsson, T. E. et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452, 638–642 (2008)
    • (2008) Nature , vol.452 , pp. 638-642
    • Thorgeirsson, T.E.1
  • 5
    • 77951751034 scopus 로고    scopus 로고
    • Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    • PID: 20418889
    • Liu, J. Z. et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat. Genet. 42, 436–440 (2010)
    • (2010) Nat. Genet. , vol.42 , pp. 436-440
    • Liu, J.Z.1
  • 6
    • 77951711343 scopus 로고    scopus 로고
    • Genome-wide meta-analyses identify multiple loci associated with smoking behavior
    • Tobacco and Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat. Genet. 42, 441–447 (2010)
    • (2010) Nat. Genet. , vol.42 , pp. 441-447
  • 7
    • 84873326172 scopus 로고    scopus 로고
    • Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans
    • PID: 23221128
    • Walsh, K. M. et al. Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. Cancer Epidemiol. Biomarkers Prev. 22, 251–260 (2013)
    • (2013) Cancer Epidemiol. Biomarkers Prev. , vol.22 , pp. 251-260
    • Walsh, K.M.1
  • 8
    • 84860333167 scopus 로고    scopus 로고
    • Smoking and genetic risk variation across populations of European, Asian, and African American ancestry—a meta-analysis of chromosome 15q25
    • PID: 22539395
    • Chen, L. S. et al. Smoking and genetic risk variation across populations of European, Asian, and African American ancestry—a meta-analysis of chromosome 15q25. Genet. Epidemiol. 36, 340–351 (2012)
    • (2012) Genet. Epidemiol. , vol.36 , pp. 340-351
    • Chen, L.S.1
  • 9
    • 77950809864 scopus 로고    scopus 로고
    • Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer
    • PID: 20332232
    • Paliwal, A. et al. Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer. Cancer Res. 70, 2779–2788 (2010)
    • (2010) Cancer Res. , vol.70 , pp. 2779-2788
    • Paliwal, A.1
  • 10
    • 84964698187 scopus 로고    scopus 로고
    • Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung
    • PID: 25187487
    • Nguyen, J. D. et al. Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung. Carcinogenesis 35, 2653–2659 (2014)
    • (2014) Carcinogenesis , vol.35 , pp. 2653-2659
    • Nguyen, J.D.1
  • 11
    • 85009060400 scopus 로고    scopus 로고
    • The role of haplotype in 15q25.1 locus in lung cancer risk: results of scanning chromosome 15
    • PID: 26282330
    • Ji, X. et al. The role of haplotype in 15q25.1 locus in lung cancer risk: results of scanning chromosome 15. Carcinogenesis 36, 1275–1283 (2015)
    • (2015) Carcinogenesis , vol.36 , pp. 1275-1283
    • Ji, X.1
  • 12
    • 74249086566 scopus 로고    scopus 로고
    • Common genetic variation and the control of HIV-1 in humans
    • PID: 20041166
    • Fellay, J. et al. Common genetic variation and the control of HIV-1 in humans. PLoS Genet. 5, e1000791 (2009)
    • (2009) PLoS Genet. , vol.5
    • Fellay, J.1
  • 13
    • 77954246243 scopus 로고    scopus 로고
    • i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study
    • PID: 20435672
    • Zhang, K., Cui, S., Chang, S., Zhang, L. & Wang, J. i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. Nucleic Acids Res. 38, W90–W95 (2010)
    • (2010) Nucleic Acids Res. , vol.38 , pp. W90-W95
    • Zhang, K.1    Cui, S.2    Chang, S.3    Zhang, L.4    Wang, J.5
  • 14
    • 84887496129 scopus 로고    scopus 로고
    • Performance comparison of two gene set analysis methods for genome-wide association study results: GSA-SNP vs i-GSEA4GWAS
    • Kwon, J. S., Kim, J., Nam, D. & Kim, S. Performance comparison of two gene set analysis methods for genome-wide association study results: GSA-SNP vs i-GSEA4GWAS. Genomics Inform. 10, 5 (2012)
    • (2012) Genomics Inform. , vol.10 , pp. 5
    • Kwon, J.S.1    Kim, J.2    Nam, D.3    Kim, S.4
  • 15
    • 77954300600 scopus 로고    scopus 로고
    • GSA-SNP: a general approach for gene set analysis of polymorphisms
    • Nam, D., Kim, J., Kim, SY. & Kim, S. GSA-SNP: a general approach for gene set analysis of polymorphisms. Nucleic Acids Res. 38, 6 (2010)
    • (2010) Nucleic Acids Res. , vol.38 , pp. 6
    • Nam, D.1    Kim, J.2    Kim, S.Y.3    Kim, S.4
  • 16
    • 84864095401 scopus 로고    scopus 로고
    • Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant
    • PID: 22665477
    • George, A. A. et al. Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant. J. Biol. Chem. 287, 25151–25162 (2012)
    • (2012) J. Biol. Chem. , vol.287 , pp. 25151-25162
    • George, A.A.1
  • 17
    • 77955434748 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study
    • PID: 20554942
    • Amos, C. I. et al. Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study. J. Natl. Cancer Inst. 102, 1199–1205 (2010)
    • (2010) J. Natl. Cancer Inst. , vol.102 , pp. 1199-1205
    • Amos, C.I.1
  • 18
    • 67449119418 scopus 로고    scopus 로고
    • Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations
    • PID: 19491260
    • Wu, C. et al. Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res. 69, 5065–5072 (2009)
    • (2009) Cancer Res. , vol.69 , pp. 5065-5072
    • Wu, C.1
  • 19
    • 84911419194 scopus 로고    scopus 로고
    • Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors
    • PID: 24943593
    • Koster, R. et al. Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors. Hum. Mol. Genet. 23, 6061–6068 (2014)
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 6061-6068
    • Koster, R.1
  • 20
    • 77954715678 scopus 로고    scopus 로고
    • Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium
    • PID: 20548021
    • Truong, T. et al. Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J. Natl. Cancer Inst. 102, 959–971 (2010)
    • (2010) J. Natl. Cancer Inst. , vol.102 , pp. 959-971
    • Truong, T.1
  • 21
    • 80053057542 scopus 로고    scopus 로고
    • Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population
    • PID: 21966413
    • Jaworowska, E. et al. Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population. PLoS ONE 6, e25057 (2011)
    • (2011) PLoS One , vol.6
    • Jaworowska, E.1
  • 22
    • 84905491435 scopus 로고    scopus 로고
    • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease
    • PID: 25033284
    • Makinen, V. P. et al. Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. PLoS Genet. 10, e1004502 (2014)
    • (2014) PLoS Genet. , vol.10
    • Makinen, V.P.1
  • 23
    • 84882449068 scopus 로고    scopus 로고
    • Genetic insights into common pathways and complex relationships among immune-mediated diseases
    • PID: 23917628
    • Parkes, M., Cortes, A., van Heel, D. A. & Brown, M. A. Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat. Rev. Genet. 14, 661–673 (2013)
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 661-673
    • Parkes, M.1    Cortes, A.2    van Heel, D.A.3    Brown, M.A.4
  • 24
    • 84906537714 scopus 로고    scopus 로고
    • Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis
    • PID: 25085501
    • Bunyavanich, S. et al. Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis. BMC Med. Genomics 7, 48 (2014)
    • (2014) BMC Med. Genomics , vol.7
    • Bunyavanich, S.1
  • 25
    • 84923169934 scopus 로고    scopus 로고
    • New genetic loci link adipose and insulin biology to body fat distribution
    • PID: 25673412
    • Shungin, D. et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature 518, 187–196 (2015)
    • (2015) Nature , vol.518 , pp. 187-196
    • Shungin, D.1
  • 26
    • 84857235523 scopus 로고    scopus 로고
    • SNP-based analysis of neuroactive ligand–receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: data from the CATIE study
    • PID: 22099390
    • Adkins, D. E. et al. SNP-based analysis of neuroactive ligand–receptor interaction pathways implicates PGE2 as a novel mediator of antipsychotic treatment response: data from the CATIE study. Schizophr. Res. 135, 200–201 (2012)
    • (2012) Schizophr. Res. , vol.135 , pp. 200-201
    • Adkins, D.E.1
  • 27
    • 84985018861 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated efficient targeted mutagenesis in Chardonnay (Vitis vinifera L.)
    • PID: 27576893
    • Ren, C. et al. CRISPR/Cas9-mediated efficient targeted mutagenesis in Chardonnay (Vitis vinifera L.). Sci. Rep. 6, 32289 (2016)
    • (2016) Sci. Rep. , vol.6
    • Ren, C.1
  • 28
    • 77951082794 scopus 로고    scopus 로고
    • Genetics of Hirschsprung disease and anorectal malformations
    • PID: 20307847
    • Mundt, E. & Bates, M. D. Genetics of Hirschsprung disease and anorectal malformations. Semin. Pediatr. Surg. 19, 107–117 (2010)
    • (2010) Semin. Pediatr. Surg. , vol.19 , pp. 107-117
    • Mundt, E.1    Bates, M.D.2
  • 29
    • 1242298513 scopus 로고    scopus 로고
    • Pathogenesis of Hirschsprung’s disease and its variants: recent progress
    • PID: 14765367
    • Puri, P. & Shinkai, T. Pathogenesis of Hirschsprung’s disease and its variants: recent progress. Semin. Pediatr. Surg. 13, 18–24 (2004)
    • (2004) Semin. Pediatr. Surg. , vol.13 , pp. 18-24
    • Puri, P.1    Shinkai, T.2
  • 30
    • 85012934934 scopus 로고    scopus 로고
    • Implication of downregulation and prospective pathway signaling of microRNA-375 in lung squamous cell carcinoma
    • Chen, W. J. et al. Implication of downregulation and prospective pathway signaling of microRNA-375 in lung squamous cell carcinoma. Pathol. Res. Pract. 213, 364–372 (2017)
    • (2017) Pathol. Res. Pract. , vol.213 , pp. 364-372
    • Chen, W.J.1
  • 31
    • 84873509714 scopus 로고    scopus 로고
    • Bioinformatics analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes
    • PID: 23111975
    • Wu, X., Zang, W., Cui, S. & Wang, M. Bioinformatics analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes. Eur. Rev. Med. Pharmacol. Sci. 16, 1582–1587 (2012)
    • (2012) Eur. Rev. Med. Pharmacol. Sci. , vol.16 , pp. 1582-1587
    • Wu, X.1    Zang, W.2    Cui, S.3    Wang, M.4
  • 32
    • 85000916418 scopus 로고    scopus 로고
    • The CHRNA5-A3-B4 gene cluster and smoking: from discovery to therapeutics
    • PID: 27871728
    • Lassi, G. et al. The CHRNA5-A3-B4 gene cluster and smoking: from discovery to therapeutics. Trends Neurosci. 39, 851–861 (2016)
    • (2016) Trends Neurosci. , vol.39 , pp. 851-861
    • Lassi, G.1
  • 33
    • 70349466340 scopus 로고    scopus 로고
    • Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations
    • PID: 19763258
    • Li, M. D. et al. Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations. PLoS One 4, e7055 (2009)
    • (2009) PLoS One , vol.4
    • Li, M.D.1
  • 34
    • 84991466824 scopus 로고    scopus 로고
    • Hemizygous deletion on chromosome 3p26.1 is associated with heavy smoking among African American subjects in the COPD gene study
    • PID: 27711239
    • Begum, F. et al. Hemizygous deletion on chromosome 3p26.1 is associated with heavy smoking among African American subjects in the COPD gene study. PLoS ONE 11, e0164134 (2016)
    • (2016) PLoS One , vol.11
    • Begum, F.1
  • 35
    • 61849154183 scopus 로고    scopus 로고
    • Genome-wide association study of smoking initiation and current smoking
    • PID: 19268276
    • Vink, J. M. et al. Genome-wide association study of smoking initiation and current smoking. Am. J. Hum. Genet. 84, 367–379 (2009)
    • (2009) Am. J. Hum. Genet. , vol.84 , pp. 367-379
    • Vink, J.M.1
  • 36
    • 66649097962 scopus 로고    scopus 로고
    • Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes
    • Saccone, N. L. et al. Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. Am. J. Med. Genet. B, Neuropsychiatr. Genet. 150B, 453–466 (2009)
    • (2009) Am. J. Med. Genet. B, Neuropsychiatr. Genet. , vol.150B , pp. 453-466
    • Saccone, N.L.1
  • 37
    • 84875929989 scopus 로고    scopus 로고
    • Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence
    • PID: 22717047
    • Biernacka, J. M. et al. Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence. Int. J. Neuropsychopharmacol. 16, 271–278 (2013)
    • (2013) Int. J. Neuropsychopharmacol. , vol.16 , pp. 271-278
    • Biernacka, J.M.1
  • 38
    • 84945248178 scopus 로고    scopus 로고
    • High throughput sequencing identifies microRNAs mediating alpha-synuclein toxicity by targeting neuroactive-ligand receptor interaction pathway in early stage of Drosophila Parkinson’s disease model
    • PID: 26361355
    • Kong, Y. et al. High throughput sequencing identifies microRNAs mediating alpha-synuclein toxicity by targeting neuroactive-ligand receptor interaction pathway in early stage of Drosophila Parkinson’s disease model. PLoS ONE 10, e0137432 (2015)
    • (2015) PLoS One , vol.10
    • Kong, Y.1
  • 39
    • 84874216248 scopus 로고    scopus 로고
    • Exploring schizophrenia drug–gene interactions through molecular network and pathway modeling
    • PID: 22195173
    • Putnam, D. K., Sun, J. & Zhao, Z. Exploring schizophrenia drug–gene interactions through molecular network and pathway modeling. AMIA Annu. Symp. Proc. 2011, 1127–1133 (2011)
    • (2011) AMIA Annu. Symp. Proc. , vol.2011 , pp. 1127-1133
    • Putnam, D.K.1    Sun, J.2    Zhao, Z.3
  • 40
    • 84963718872 scopus 로고    scopus 로고
    • Pathway network analyses for autism reveal multisystem involvement, major overlaps with other diseases and convergence upon MAPK and calcium signaling
    • PID: 27055244
    • Wen, Y., Alshikho, M. J. & Herbert, M. R. Pathway network analyses for autism reveal multisystem involvement, major overlaps with other diseases and convergence upon MAPK and calcium signaling. PLoS One 11, e0153329 (2016)
    • (2016) PLoS One , vol.11
    • Wen, Y.1    Alshikho, M.J.2    Herbert, M.R.3
  • 41
    • 80054887592 scopus 로고    scopus 로고
    • Ion channels and transporters in cancer. 4. Remodeling of Ca(2+) signaling in tumorigenesis: role of Ca(2+) transport
    • PID: 21593447
    • Lee, J. M., Davis, F. M., Roberts-Thomson, S. J. & Monteith, G. R. Ion channels and transporters in cancer. 4. Remodeling of Ca(2+) signaling in tumorigenesis: role of Ca(2+) transport. Am. J. Physiol. Cell Physiol. 301, C969–C976 (2011)
    • (2011) Am. J. Physiol. Cell Physiol. , vol.301 , pp. C969-C976
    • Lee, J.M.1    Davis, F.M.2    Roberts-Thomson, S.J.3    Monteith, G.R.4
  • 42
    • 84873900703 scopus 로고    scopus 로고
    • Targeting Ca(2)(+) transport in cancer: close reality or long perspective?
    • PID: 23294334
    • Prevarskaya, N., Skryma, R. & Shuba, Y. Targeting Ca(2)(+) transport in cancer: close reality or long perspective? Expert Opin. Ther. Targets 17, 225–241 (2013)
    • (2013) Expert Opin. Ther. Targets , vol.17 , pp. 225-241
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 43
    • 84941185573 scopus 로고    scopus 로고
    • Plasma membrane calcium channels in cancer: alterations and consequences for cell proliferation and migration
    • PID: 26072287
    • Deliot, N. & Constantin, B. Plasma membrane calcium channels in cancer: alterations and consequences for cell proliferation and migration. Biochim. Biophys. Acta 1848, 2512–2522 (2015)
    • (2015) Biochim. Biophys. Acta , vol.1848 , pp. 2512-2522
    • Deliot, N.1    Constantin, B.2
  • 44
    • 84978402775 scopus 로고    scopus 로고
    • Genetic variants and risk of prostate cancer using pathway analysis of a genome-wide association study
    • PID: 27268928
    • Kim, Y. S., Kim, Y., Choi, J. W., Oh, H. E. & Lee, J. H. Genetic variants and risk of prostate cancer using pathway analysis of a genome-wide association study. Neoplasma 63, 629–634 (2016)
    • (2016) Neoplasma , vol.63 , pp. 629-634
    • Kim, Y.S.1    Kim, Y.2    Choi, J.W.3    Oh, H.E.4    Lee, J.H.5
  • 45
    • 84945294506 scopus 로고    scopus 로고
    • Germline mutations causing familial lung cancer
    • PID: 26178433
    • Tomoshige, K. et al. Germline mutations causing familial lung cancer. J. Hum. Genet. 60, 597–603 (2015)
    • (2015) J. Hum. Genet. , vol.60 , pp. 597-603
    • Tomoshige, K.1
  • 46
    • 84863223162 scopus 로고    scopus 로고
    • Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue
    • PID: 22223368
    • Frullanti, E. et al. Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue. Int. J. Cancer 131, E643–E648 (2012)
    • (2012) Int. J. Cancer , vol.131 , pp. E643-E648
    • Frullanti, E.1
  • 47
    • 84969662729 scopus 로고    scopus 로고
    • Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1
    • PID: 27156840
    • Lee, J., Katzenmaier, E. M., Kopitz, J. & Gebert, J. Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1. Cell Signal. 28, 1105–1113 (2016)
    • (2016) Cell Signal. , vol.28 , pp. 1105-1113
    • Lee, J.1    Katzenmaier, E.M.2    Kopitz, J.3    Gebert, J.4
  • 48
    • 84931074310 scopus 로고    scopus 로고
    • PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma
    • PID: 25970784
    • Cheung, A. K. et al. PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma. Oncotarget 6, 13434–13447 (2015)
    • (2015) Oncotarget , vol.6 , pp. 13434-13447
    • Cheung, A.K.1
  • 49
    • 84981316474 scopus 로고    scopus 로고
    • Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: Role of endothelin-A receptor-activated ABCB1 expression
    • Englinger, B. et al. Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression. Oncotarget. 7, 50161–50179 (2016)
    • (2016) Oncotarget , vol.7 , pp. 50161-50179
    • Englinger, B.1
  • 50
    • 52049115449 scopus 로고    scopus 로고
    • OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation
    • PID: 18714356
    • Cui, Y. et al. OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation. PLoS One 3, e2990 (2008)
    • (2008) PLoS One , vol.3
    • Cui, Y.1
  • 51
    • 48649086619 scopus 로고    scopus 로고
    • Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer
    • PID: 18616821
    • Anglim, P. P. et al. Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. Mol. Cancer 7, 62 (2008)
    • (2008) Mol. Cancer , vol.7
    • Anglim, P.P.1
  • 52
    • 79954622199 scopus 로고    scopus 로고
    • Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis
    • PID: 21487037
    • Gentile, A., Lazzari, L., Benvenuti, S., Trusolino, L. & Comoglio, P. M. Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis. Cancer Res. 71, 3132–3141 (2011)
    • (2011) Cancer Res. , vol.71 , pp. 3132-3141
    • Gentile, A.1    Lazzari, L.2    Benvenuti, S.3    Trusolino, L.4    Comoglio, P.M.5
  • 53
    • 84863384604 scopus 로고    scopus 로고
    • NKX2-1/TITF1/TTF-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma
    • PID: 22439932
    • Yamaguchi, T. et al. NKX2-1/TITF1/TTF-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma. Cancer Cell. 21, 348–361 (2012)
    • (2012) Cancer Cell. , vol.21 , pp. 348-361
    • Yamaguchi, T.1
  • 54
    • 47349103842 scopus 로고    scopus 로고
    • Environment And Genetics in Lung cancer Etiology (EAGLE) study: an integrative population-based case-control study of lung cancer
    • PID: 18538025
    • Landi, M. T. et al. Environment And Genetics in Lung cancer Etiology (EAGLE) study: an integrative population-based case-control study of lung cancer. BMC Public Health 8, 203 (2008)
    • (2008) BMC Public Health , vol.8
    • Landi, M.T.1
  • 55
    • 84903585835 scopus 로고    scopus 로고
    • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer
    • PID: 24880342
    • Wang, Y. et al. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat. Genet. 46, 736–741 (2014)
    • (2014) Nat. Genet. , vol.46 , pp. 736-741
    • Wang, Y.1
  • 56
    • 85020451435 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
    • McKay, J. et al. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat. Genet. 49, 1126–1132 (2017)
    • (2017) Nat. Genet. , vol.49 , pp. 1126-1132
    • McKay, J.1
  • 57
    • 84864830720 scopus 로고    scopus 로고
    • Molecular signature of smoking in human lung tissues
    • PID: 22659451
    • Bosse, Y. et al. Molecular signature of smoking in human lung tissues. Cancer Res. 72, 3753–3763 (2012)
    • (2012) Cancer Res. , vol.72 , pp. 3753-3763
    • Bosse, Y.1
  • 58
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • PID: 19543373
    • Howie, B. N., Donnelly, P. & Marchini, J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009)
    • (2009) PLoS Genet. , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 59
    • 0032919364 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • PID: 9847135
    • Ogata, H. et al. KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res. 27, 29–34 (1999)
    • (1999) Nucleic Acids Res. , vol.27 , pp. 29-34
    • Ogata, H.1
  • 60
    • 33644875286 scopus 로고    scopus 로고
    • The Gene Ontology (GO) project in 2006
    • Gene Ontology Consortium. The Gene Ontology (GO) project in 2006. Nucleic Acids Res. 34, D322–D326 (2006)
    • (2006) Nucleic Acids Res , vol.34 , pp. D322-D326
  • 61
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • PID: 16199517
    • Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. U.S.A. 102, 15545–15550 (2005)
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 62
    • 36249029788 scopus 로고    scopus 로고
    • Pathway-based approaches for analysis of genomewide association studies
    • PID: 17966091
    • Wang, K., Li, M. & Bucan, M. Pathway-based approaches for analysis of genomewide association studies. Am. J. Hum. Genet. 81, 1278–1283 (2007)
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 1278-1283
    • Wang, K.1    Li, M.2    Bucan, M.3
  • 63
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • PID: 12925520
    • Irizarry, R. A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249–264 (2003)
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1
  • 64
    • 33750964487 scopus 로고    scopus 로고
    • Quality assessment of Affymetrix GeneChip data
    • PID: 17069513
    • Heber, S. & Sick, B. Quality assessment of Affymetrix GeneChip data. OMICS 10, 358–368 (2006)
    • (2006) OMICS , vol.10 , pp. 358-368
    • Heber, S.1    Sick, B.2
  • 65
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • da Huang, W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44–57 (2009)
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3


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