Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

Nature Neuroscience

Volumn 21, Issue 8, 2018, Pages 1117-1125

  Jaffe, Andrew E ^a,b,c,d   Straub, Richard E ^a   Shin, Joo Heon ^a   Tao, Ran ^a   Gao, Yuan ^a   Collado Torres, Leonardo ^a,b,c   Kam Thong, Tony ^e   Xi, Hualin S ^f   Quan, Jie ^f   Chen, Qiang ^a   Colantuoni, Carlo ^a,d   Ulrich, William S ^a   Maher, Brady J ^a,d   Deep Soboslay, Amy ^a   Cross, Alan J ^g   Brandon, Nicholas J ^g   Leek, Jeffrey T ^b,c   Hyde, Thomas M ^a,d   Kleinman, Joel E ^a,d   Weinberger, Daniel R ^a,d  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c Johns Hopkins University   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

^f PFIZER INC   (United States)

^g ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME;

ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CONTROLLED STUDY; EXPRESSION QUANTITATIVE TRAIT LOCUS; GENE EXPRESSION; GENETIC REGULATION; GENETIC RISK; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PATHOGENESIS; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; RNA SEQUENCE; SCHIZOPHRENIA; SYNAPSE; ADOLESCENT; ADULT; AUTOPSY; CHILD; CHRONIC DISEASE; FEMALE; GENE EXPRESSION REGULATION; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; INFANT; MALE; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PREGNANCY; PRESCHOOL CHILD; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AUTOPSY; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DATABASES, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; INFANT; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; PREGNANCY; SCHIZOPHRENIA; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 85051539595     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/s41593-018-0197-y     Document Type: Article

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