QSVA framework for RNA quality correction in differential expression analysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 27, 2017, Pages 7130-7135

  Jaffe, Andrew E ^a,b,c   Tao, Ran ^a   Norris, Alexis L ^d,e   Kealhofer, Marc ^a,b   Nellore, Abhinav ^b,c   Shin, Joo Heon ^a   Kim, Dewey ^a   Jia, Yankai ^a   Hyde, Thomas M ^a,d   Kleinman, Joel E ^a,d   Straub, Richard E ^a   Leek, Jeffrey T ^b,c   Weinberger, Daniel R ^a,d  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c Johns Hopkins University   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

Differential expression analysis; RNA quality; RNA sequencing; Statistical modeling

Indexed keywords

RNA; TRANSCRIPTOME;

ARTICLE; BRAIN REGION; DORSOLATERAL PREFRONTAL CORTEX; GENE EXPRESSION; GRAY MATTER; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RNA DEGRADATION; RNA SEQUENCE; SCHIZOPHRENIA; TRANSCRIPTOMICS; ALGORITHM; ANIMAL; BIOLOGY; DNA MICROARRAY; DNA REPLICATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HIGH THROUGHPUT SEQUENCING; METABOLISM; PROCEDURES; SEQUENCE ANALYSIS;

ALGORITHMS; ANIMALS; COMPUTATIONAL BIOLOGY; DNA REPLICATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOTYPE; GRAY MATTER; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA; SCHIZOPHRENIA; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 85021725602     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1617384114     Document Type: Article

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