Maternal antimicrobial use at delivery has a stronger impact than mode of delivery on bifidobacterial colonization in infants: a pilot study

Journal of Perinatology

Volumn 38, Issue 9, 2018, Pages 1174-1181

  Imoto, Naruaki ^a   Morita, Hiroto ^b   Amanuma, Fumitaka ^c   Maruyama, Hidekazu ^c   Watanabe, Shin ^a   Hashiguchi, Naoyuki ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b Asahi Soft Drinks Co Ltd   (Japan)

^c Iwate Prefectural Iwai Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIINFECTIVE AGENT; CEFAZOLIN;

ADULT; ARTICLE; BACTERIAL COLONIZATION; BIFIDOBACTERIUM; CESAREAN SECTION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DRUG EFFECT; DRUG USE; FECES; FEMALE; GENETIC ANALYSIS; GESTATIONAL AGE; HUMAN; INFANT; INTESTINE FLORA; JAPANESE (PEOPLE); MALE; MATERNAL EXPOSURE; MICROBIAL DIVERSITY; NEXT GENERATION SEQUENCING; NONHUMAN; NORMAL HUMAN; OBSTETRIC DELIVERY; PILOT STUDY; POPULATION ABUNDANCE; PRENATAL DRUG EXPOSURE; PREOPERATIVE PERIOD; SINGLE DRUG DOSE; SPECIES DIVERSITY; ISOLATION AND PURIFICATION; MICROBIOLOGY; NEWBORN; PREGNANCY;

ADULT; ANTI-INFECTIVE AGENTS; BIFIDOBACTERIUM; CROSS-SECTIONAL STUDIES; DELIVERY, OBSTETRIC; FECES; FEMALE; GASTROINTESTINAL MICROBIOME; HUMANS; INFANT; INFANT, NEWBORN; MALE; MATERNAL EXPOSURE; PILOT PROJECTS; PREGNANCY;

EID: 85050643513     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/s41372-018-0172-1     Document Type: Article

References (32)

1. Blaut M, Clavel T. Metabolic diversity of the intestinal microbiota: implications for health and disease. J Nutr. 2007;137:751s–5s.
2. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–8.
3. Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. 2010;464:59–65.
4. Harmsen HJ, Wildeboer-Veloo AC, Raangs GC, Wagendorp AA, Klijn N, Bindels JG, et al. Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods. J Pediatr Gastroenterol Nutr. 2000;30:61–7.
5. Azad MB, Konya T, Maughan H, Guttman DS, Field CJ, Chari RS, et al. Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. CMAJ. 2013;185:385–94.
6. Nakayama J, Watanabe K, Jiang J, Matsuda K, Chao SH, Haryono P, et al. Diversity in gut bacterial community of school-age children in Asia. Sci Rep. 2015;5:8397.
7. Nishijima S, Suda W, Oshima K, Kim SW, Hirose Y, Morita H, et al. The gut microbiome of healthy Japanese and its microbial and functional uniqueness. DNA Res. 2016;23:125–33.
8. Vangay P, Ward T, Gerber JS, Knights D. Antibiotics, pediatric dysbiosis, and disease. Cell Host Microbe. 2015;17:553–64.
9. Wopereis H, Oozeer R, Knipping K, Belzer C, Knol J. The first thousand days—intestinal microbiology of early life: establishing a symbiosis. Pediatr Allergy Immunol. 2014;25:428–38.
10. Hong PY, Lee BW, Aw M, Shek LP, Yap GC, Chua KY, et al. Comparative analysis of fecal microbiota in infants with and without eczema. PLoS One. 2010;5:e9964.
11. Van Zwol A, Van Den Berg A, Knol J, Twisk JW, Fetter WP, Van Elburg RM. Intestinal microbiota in allergic and nonallergic 1-year-old very low birth weight infants after neonatal glutamine supplementation. Acta Paediatr. 2010;99:1868–74.
12. Guarner F, Malagelada JR. Gut flora in health and disease. Lancet. 2003;361:512–9.
13. Salminen S, Isolauri E. Intestinal colonization, microbiota, and probiotics. J Pediatr. 2006;149: S115–20.
14. Turroni F, Ribbera A, Foroni E, van Sinderen D, Ventura M. Human gut microbiota and bifidobacteria: from composition to functionality. Antonie Van Leeuwenhoek. 2008;94:35–50.
15. Fouhy F, Ross RP, Fitzgerald GF, Stanton C, Cotter PD. Composition of the early intestinal microbiota: knowledge, knowledge gaps and the use of high-throughput sequencing to address these gaps. Gut Microbes. 2012;3:203–20.
16. Turroni F, Peano C, Pass DA, Foroni E, Severgnini M, Claesson MJ, et al. Diversity of bifidobacteria within the infant gut microbiota. PLoS One. 2012;7:e36957.
17. Mikami K, Takahashi H, Kimura M, Isozaki M, Izuchi K, Shibata R, et al. Influence of maternal bifidobacteria on the establishment of bifidobacteria colonizing the gut in infants. Pediatr Res. 2009;65:669–74.
18. Gronlund MM, Lehtonen OP, Eerola E, Kero P. Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Pediatr Gastroenterol Nutr. 1999;28:19–25.
19. Penders J, Thijs C, Vink C, Stelma FF, Snijders B, Kummeling I, et al. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics. 2006;118:511–21.
20. Biasucci G, Rubini M, Riboni S, Morelli L, Bessi E, Retetangos C. Mode of delivery affects the bacterial community in the newborn gut. Early Hum Dev. 2010;86:13–15.
21. Lee E, Kim BJ, Kang MJ, Choi KY, Cho HJ, Kim Y, et al. Dynamics of gut microbiota according to the delivery mode in healthy korean infants. Allergy, Asthma Immunol Res. 2016;8:471–7.
22. Costantine MM, Rahman M, Ghulmiyah L, Byers BD, Longo M, Wen T, et al. Timing of perioperative antibiotics for cesarean delivery: a metaanalysis. Am J Obstet Gynecol. 2008;199:301.e301–306.
23. Gomez-Arango LF, Barrett HL, McIntyre HD, Callaway LK, Morrison M, Dekker Nitert M. Antibiotic treatment at delivery shapes the initial oral microbiome in neonates. Sci Rep. 2017;7:43481.
24. Azad MB, Konya T, Persaud RR, Guttman DS, Chari RS, Field CJ, et al. Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study. BJOG. 2016;123:983–93.
25. Mazzola G, Murphy K, Ross RP, Di Gioia D, Biavati B, Corvaglia LT, et al. Early gut microbiota perturbations following intrapartum antibiotic prophylaxis to prevent group B Streptococcal disease. PLoS One. 2016;11:e0157527.
26. Corvaglia L, Tonti G, Martini S, Aceti A, Mazzola G, Aloisio I, et al. Influence of intrapartum antibiotic prophylaxis for group B Streptococcus on gut microbiota in the first month of life. J Pediatr Gastroenterol Nutr. 2016;62:304–8.
27. Nishimoto Y, Mizutani S, Nakajima T, Hosoda F, Watanabe H, Saito Y, et al. High stability of faecal microbiome composition in guanidine thiocyanate solution at room temperature and robustness during colonoscopy. Gut. 2016;65:1574–5.
28. Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods. 2010;7:335–6.
29. Aloisio I, Quagliariello A, De Fanti S, Luiselli D, De Filippo C, Albanese D, et al. Evaluation of the effects of intrapartum antibiotic prophylaxis on newborn intestinal microbiota using a sequencing approach targeted to multi hypervariable 16S rDNA regions. Appl Microbiol Biotechnol. 2016;100:5537–46.
30. Huurre A, Kalliomaki M, Rautava S, Rinne M, Salminen S, Isolauri E. Mode of delivery - effects on gut microbiota and humoral immunity. Neonatology. 2008;93:236–40.
31. Ishizeki S, Sugita M, Takata M, Yaeshima T. Effect of administration of bifidobacteria on intestinal microbiota in low-birth-weight infants and transition of administered bifidobacteria: a comparison between one-species and three-species administration. Anaerobe. 2013;23:38–44.
32. Yamasaki C, Totsu S, Uchiyama A, Nakanishi H, Masumoto K, Washio Y, et al. Effect of Bifidobacterium administration on very-low-birthweight infants. Pediatr Int. 2012;54:651–6.