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Volumn 198, Issue 2, 2018, Pages 220-231

Prognostic and pathogenic role of angiopoietin-1 and -2 in pneumonia

Author keywords

Acute respiratory distress syndrome; Endothelial permeability; Pneumolysin; Streptococcus pneumoniae

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; BILIRUBIN; C REACTIVE PROTEIN; CREATININE; MESSENGER RNA; PNEUMOLYSIN; PROCALCITONIN;

EID: 85050076816     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201708-1733OC     Document Type: Article
Times cited : (55)

References (50)
  • 1
    • 39049085847 scopus 로고    scopus 로고
    • Acute lower respiratory tract infection
    • Mizgerd JP. Acute lower respiratory tract infection. N Engl J Med 2008; 358:716–727.
    • (2008) N Engl J Med , vol.358 , pp. 716-727
    • Mizgerd, J.P.1
  • 2
    • 85050124690 scopus 로고    scopus 로고
    • The top 10 causes of death worldwide
    • updated July 2013.
    • World Health Organiation. The top 10 causes of death worldwide. Fact Sheet No. 310 [2013; updated July 2013]. Available from: http://who.int/mediacentre/factsheets/fs310/en/index.html.
    • (2013) Fact Sheet No. 310
  • 4
    • 84877109717 scopus 로고    scopus 로고
    • Angiopoietin signaling in the vasculature
    • Eklund L, Saharinen P. Angiopoietin signaling in the vasculature. Exp Cell Res 2013;319:1271–1280.
    • (2013) Exp Cell Res , vol.319 , pp. 1271-1280
    • Eklund, L.1    Saharinen, P.2
  • 5
    • 67650753834 scopus 로고    scopus 로고
    • The role of the angiopoietins in vascular morphogenesis
    • Thomas M, Augustin HG. The role of the angiopoietins in vascular morphogenesis. Angiogenesis 2009;12:125–137.
    • (2009) Angiogenesis , vol.12 , pp. 125-137
    • Thomas, M.1    Augustin, H.G.2
  • 6
    • 32244436305 scopus 로고    scopus 로고
    • Angiopoietin-2 sensitizes endothelial cells to TNF-a and has a crucial role in the induction of inflammation
    • Fiedler U, Reiss Y, Scharpfenecker M, Grunow V, Koidl S, Thurston G, et al. Angiopoietin-2 sensitizes endothelial cells to TNF-a and has a crucial role in the induction of inflammation. Nat Med 2006;12: 235–239.
    • (2006) Nat Med , vol.12 , pp. 235-239
    • Fiedler, U.1    Reiss, Y.2    Scharpfenecker, M.3    Grunow, V.4    Koidl, S.5    Thurston, G.6
  • 8
    • 0034036689 scopus 로고    scopus 로고
    • Angiopoietin-1 protects the adult vasculature against plasma leakage
    • Thurston G, Rudge JS, Ioffe E, Zhou H, Ross L, Croll SD, et al. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 2000;6:460–463.
    • (2000) Nat Med , vol.6 , pp. 460-463
    • Thurston, G.1    Rudge, J.S.2    Ioffe, E.3    Zhou, H.4    Ross, L.5    Croll, S.D.6
  • 10
    • 80054953975 scopus 로고    scopus 로고
    • Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense
    • David S, Ghosh CC, Mukherjee A, Parikh SM. Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense. Arterioscler Thromb Vasc Biol 2011;31:2643–2652.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2643-2652
    • David, S.1    Ghosh, C.C.2    Mukherjee, A.3    Parikh, S.M.4
  • 11
  • 12
    • 65549145050 scopus 로고    scopus 로고
    • Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2
    • Sako K, Fukuhara S, Minami T, Hamakubo T, Song H, Kodama T, et al. Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2. J Biol Chem 2009;284:5592–5601.
    • (2009) J Biol Chem , vol.284 , pp. 5592-5601
    • Sako, K.1    Fukuhara, S.2    Minami, T.3    Hamakubo, T.4    Song, H.5    Kodama, T.6
  • 13
    • 14944377120 scopus 로고    scopus 로고
    • The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism
    • Scharpfenecker M, Fiedler U, Reiss Y, Augustin HG. The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism. J Cell Sci 2005;118:771–780.
    • (2005) J Cell Sci , vol.118 , pp. 771-780
    • Scharpfenecker, M.1    Fiedler, U.2    Reiss, Y.3    Augustin, H.G.4
  • 14
    • 0034730784 scopus 로고    scopus 로고
    • Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions
    • Gamble JR, Drew J, Trezise L, Underwood A, Parsons M, Kasminkas L, et al. Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circ Res 2000;87:603–607.
    • (2000) Circ Res , vol.87 , pp. 603-607
    • Gamble, J.R.1    Drew, J.2    Trezise, L.3    Underwood, A.4    Parsons, M.5    Kasminkas, L.6
  • 15
    • 2542453735 scopus 로고    scopus 로고
    • The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies
    • Fiedler U, Scharpfenecker M, Koidl S, Hegen A, Grunow V, Schmidt JM, et al. The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies. Blood 2004;103:4150–4156.
    • (2004) Blood , vol.103 , pp. 4150-4156
    • Fiedler, U.1    Scharpfenecker, M.2    Koidl, S.3    Hegen, A.4    Grunow, V.5    Schmidt, J.M.6
  • 16
    • 44449145867 scopus 로고    scopus 로고
    • Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome
    • Gallagher DC, Parikh SM, Balonov K, Miller A, Gautam S, Talmor D, et al. Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome. Shock 2008;29:656–661.
    • (2008) Shock , vol.29 , pp. 656-661
    • Gallagher, D.C.1    Parikh, S.M.2    Balonov, K.3    Miller, A.4    Gautam, S.5    Talmor, D.6
  • 18
    • 79953218683 scopus 로고    scopus 로고
    • Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis
    • Ricciuto DR, dos Santos CC, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, et al. Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med 2011;39:702–710.
    • (2011) Crit Care Med , vol.39 , pp. 702-710
    • Ricciuto, D.R.1    Dos Santos, C.C.2    Hawkes, M.3    Toltl, L.J.4    Conroy, A.L.5    Rajwans, N.6
  • 20
    • 85076584859 scopus 로고    scopus 로고
    • Role of angiopoietins Ang-1 and Ang-2 for the development of acute lung injury in pneumococcal pneumonia
    • Gutbier B, Reppe K, Neuhauß A-K, Kaufmann J, Weissmann N, Morawitz L, et al. Role of angiopoietins Ang-1 and Ang-2 for the development of acute lung injury in pneumococcal pneumonia [abstract]. Am J Respir Crit Care Med 2011;183:A1982.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. A1982
    • Gutbier, B.1    Reppe, K.2    Neuhauß, A.-K.3    Kaufmann, J.4    Weissmann, N.5    Morawitz, L.6
  • 22
    • 4043066471 scopus 로고    scopus 로고
    • CAPNETZ: Community-acquired Pneumonia Competence Network
    • Welte T, Suttorp N, Marre R. CAPNETZ: Community-acquired Pneumonia Competence Network. Infection 2004;32:234–238.
    • (2004) Infection , vol.32 , pp. 234-238
    • Welte, T.1    Suttorp, N.2    Marre, R.3
  • 23
    • 33745177635 scopus 로고    scopus 로고
    • CRB-65 predicts death from community-acquired pneumonia
    • Bauer TT, Ewig S, Marre R, Suttorp N, Welte T; CAPNETZ Study Group. CRB-65 predicts death from community-acquired pneumonia. J Intern Med 2006;260:93–101.
    • (2006) J Intern Med , vol.260 , pp. 93-101
    • Bauer, T.T.1    Ewig, S.2    Marre, R.3    Suttorp, N.4    Welte, T.5
  • 24
    • 84982151887 scopus 로고    scopus 로고
    • PROGRESS: Prospective observational study on hospitalized community acquired pneumonia
    • Ahnert P, Creutz P, Scholz M, Schütte H, Engel C, Hossain H, et al.; PROGRESS Study Group. PROGRESS: prospective observational study on hospitalized community acquired pneumonia. BMC Pulm Med 2016;16:108.
    • (2016) BMC Pulm Med , vol.16 , pp. 108
    • Ahnert, P.1    Creutz, P.2    Scholz, M.3    Schütte, H.4    Engel, C.5    Hossain, H.6
  • 25
    • 0025642947 scopus 로고
    • Role of actin and myosin in the control of paracellular permeability in pig, rat and human vascular endothelium
    • Schnittler HJ, Wilke A, Gress T, Suttorp N, Drenckhahn D. Role of actin and myosin in the control of paracellular permeability in pig, rat and human vascular endothelium. J Physiol 1990;431:379–401.
    • (1990) J Physiol , vol.431 , pp. 379-401
    • Schnittler, H.J.1    Wilke, A.2    Gress, T.3    Suttorp, N.4    Drenckhahn, D.5
  • 26
    • 0027754169 scopus 로고
    • A morphological biosensor for mammalian cells
    • Giaever I, Keese CR. A morphological biosensor for mammalian cells. Nature 1993;366:591–592.
    • (1993) Nature , vol.366 , pp. 591-592
    • Giaever, I.1    Keese, C.R.2
  • 27
    • 0024586383 scopus 로고
    • Expression of the pneumolysin gene in Escherichia coli: Rapid purification and biological properties
    • Mitchell TJ, Walker JA, Saunders FK, Andrew PW, Boulnois GJ. Expression of the pneumolysin gene in Escherichia coli: rapid purification and biological properties. Biochim Biophys Acta 1989; 1007:67–72.
    • (1989) Biochim Biophys Acta , vol.1007 , pp. 67-72
    • Mitchell, T.J.1    Walker, J.A.2    Saunders, F.K.3    Andrew, P.W.4    Boulnois, G.J.5
  • 28
    • 33746883220 scopus 로고    scopus 로고
    • A novel siRNA–lipoplex technology for RNA interference in the mouse vascular endothelium
    • Santel A, Aleku M, Keil O, Endruschat J, Esche V, Fisch G, et al. A novel siRNA–lipoplex technology for RNA interference in the mouse vascular endothelium. Gene Ther 2006;13:1222–1234.
    • (2006) Gene Ther , vol.13 , pp. 1222-1234
    • Santel, A.1    Aleku, M.2    Keil, O.3    Endruschat, J.4    Esche, V.5    Fisch, G.6
  • 29
  • 30
    • 84875836835 scopus 로고    scopus 로고
    • Management-based risk prediction in community-acquired pneumonia by scores and biomarkers
    • Kolditz M, Ewig S, Höffken G. Management-based risk prediction in community-acquired pneumonia by scores and biomarkers. Eur Respir J 2013;41:974–984.
    • (2013) Eur Respir J , vol.41 , pp. 974-984
    • Kolditz, M.1    Ewig, S.2    Höffken, G.3
  • 31
    • 70350353411 scopus 로고    scopus 로고
    • New perspectives on community-acquired pneumonia in 388 406 patients: Results from a nationwide mandatory performance measurement programme in healthcare quality
    • Ewig S, Birkner N, Strauss R, Schaefer E, Pauletzki J, Bischoff H, et al. New perspectives on community-acquired pneumonia in 388 406 patients: results from a nationwide mandatory performance measurement programme in healthcare quality. Thorax 2009;64: 1062–1069.
    • (2009) Thorax , vol.64 , pp. 1062-1069
    • Ewig, S.1    Birkner, N.2    Strauss, R.3    Schaefer, E.4    Pauletzki, J.5    Bischoff, H.6
  • 32
    • 77957197403 scopus 로고    scopus 로고
    • Value of severity scales in predicting mortality from community-acquired pneumonia: Systematic review and meta-analysis
    • Loke YK, Kwok CS, Niruban A, Myint PK. Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis. Thorax 2010;65:884–890.
    • (2010) Thorax , vol.65 , pp. 884-890
    • Loke, Y.K.1    Kwok, C.S.2    Niruban, A.3    Myint, P.K.4
  • 33
    • 77957192940 scopus 로고    scopus 로고
    • Severity assessment tools for predicting mortality in hospitalised patients with community-acquired pneumonia: Systematic review and meta-analysis
    • Chalmers JD, Singanayagam A, Akram AR, Mandal P, Short PM, Choudhury G, et al. Severity assessment tools for predicting mortality in hospitalised patients with community-acquired pneumonia: systematic review and meta-analysis. Thorax 2010;65: 878–883.
    • (2010) Thorax , vol.65 , pp. 878-883
    • Chalmers, J.D.1    Singanayagam, A.2    Akram, A.R.3    Mandal, P.4    Short, P.M.5    Choudhury, G.6
  • 34
    • 80054754800 scopus 로고    scopus 로고
    • Severity assessment tools to guide ICU admission in community-acquired pneumonia: Systematic review and meta-analysis
    • Chalmers JD, Mandal P, Singanayagam A, Akram AR, Choudhury G, Short PM, et al. Severity assessment tools to guide ICU admission in community-acquired pneumonia: systematic review and meta-analysis. Intensive Care Med 2011;37:1409–1420.
    • (2011) Intensive Care Med , vol.37 , pp. 1409-1420
    • Chalmers, J.D.1    Mandal, P.2    Singanayagam, A.3    Akram, A.R.4    Choudhury, G.5    Short, P.M.6
  • 35
    • 84861513903 scopus 로고    scopus 로고
    • Plasma angiopoietin-2 in clinical acute lung injury: Prognostic and pathogenetic significance
    • NHLBI ARDS Network
    • Calfee CS, Gallagher D, Abbott J, Thompson BT, Matthay MA; NHLBI ARDS Network. Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance. Crit Care Med 2012;40: 1731–1737.
    • (2012) Crit Care Med , vol.40 , pp. 1731-1737
    • Calfee, C.S.1    Gallagher, D.2    Abbott, J.3    Thompson, B.T.4    Matthay, M.A.5
  • 37
    • 85011324270 scopus 로고    scopus 로고
    • Serum angiopoietin-2 level as a potential biomarker in psoriasis vulgaris
    • Takahashi T, Asano Y, Shibata S, Tada Y, Sato S. Serum angiopoietin-2 level as a potential biomarker in psoriasis vulgaris. J Dermatol 2017; 44:205–206.
    • (2017) J Dermatol , vol.44 , pp. 205-206
    • Takahashi, T.1    Asano, Y.2    Shibata, S.3    Tada, Y.4    Sato, S.5
  • 38
    • 84930883815 scopus 로고    scopus 로고
    • Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies
    • Calfee CS, Janz DR, Bernard GR, May AK, Kangelaris KN, Matthay MA, et al. Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. Chest 2015;147:1539–1548.
    • (2015) Chest , vol.147 , pp. 1539-1548
    • Calfee, C.S.1    Janz, D.R.2    Bernard, G.R.3    May, A.K.4    Kangelaris, K.N.5    Matthay, M.A.6
  • 39
    • 85034787690 scopus 로고    scopus 로고
    • Severity scores and community-acquired pneumonia: Time to move forward
    • Waterer G. Severity scores and community-acquired pneumonia: time to move forward. Am J Respir Crit Care Med 2017;196:1236–1238.
    • (2017) Am J Respir Crit Care Med , vol.196 , pp. 1236-1238
    • Waterer, G.1
  • 40
    • 0027515802 scopus 로고
    • Expression of Tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage
    • Schnürch H, Risau W. Expression of Tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage. Development 1993;119:957–968.
    • (1993) Development , vol.119 , pp. 957-968
    • Schnürch, H.1    Risau, W.2
  • 41
    • 0036100216 scopus 로고    scopus 로고
    • The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection
    • Cockeran R, Anderson R, Feldman C. The role of pneumolysin in the pathogenesis of Streptococcus pneumoniae infection. Curr Opin Infect Dis 2002;15:235–239.
    • (2002) Curr Opin Infect Dis , vol.15 , pp. 235-239
    • Cockeran, R.1    Anderson, R.2    Feldman, C.3
  • 42
    • 33750699301 scopus 로고    scopus 로고
    • Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death
    • Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, et al. Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death. Nat Med 2006;12:1286–1293.
    • (2006) Nat Med , vol.12 , pp. 1286-1293
    • Bhandari, V.1    Choo-Wing, R.2    Lee, C.G.3    Zhu, Z.4    Nedrelow, J.H.5    Chupp, G.L.6
  • 43
    • 0034673554 scopus 로고    scopus 로고
    • Tumor necrosis factor-a upregulates angiopoietin-2 in human umbilical vein endothelial cells
    • Kim I, Kim JH, Ryu YS, Liu M, Koh GY. Tumor necrosis factor-a upregulates angiopoietin-2 in human umbilical vein endothelial cells. Biochem Biophys Res Commun 2000;269:361–365.
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 361-365
    • Kim, I.1    Kim, J.H.2    Ryu, Y.S.3    Liu, M.4    Koh, G.Y.5
  • 44
    • 84856040194 scopus 로고    scopus 로고
    • Streptococcus pneumoniae induces exocytosis of Weibel-Palade bodies in pulmonary endothelial cells
    • Lüttge M, Fulde M, Talay SR, Nerlich A, Rohde M, Preissner KT, et al. Streptococcus pneumoniae induces exocytosis of Weibel-Palade bodies in pulmonary endothelial cells. Cell Microbiol 2012;14: 210–225.
    • (2012) Cell Microbiol , vol.14 , pp. 210-225
    • Lüttge, M.1    Fulde, M.2    Talay, S.R.3    Nerlich, A.4    Rohde, M.5    Preissner, K.T.6
  • 45
    • 84857132877 scopus 로고    scopus 로고
    • Agonist of growth hormone–releasing hormone reduces pneumolysin-induced pulmonary permeability edema
    • Lucas R, Sridhar S, Rick FG, Gorshkov B, Umapathy NS, Yang G, et al. Agonist of growth hormone–releasing hormone reduces pneumolysin-induced pulmonary permeability edema. Proc Natl Acad Sci USA 2012;109:2084–2089.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 2084-2089
    • Lucas, R.1    Sridhar, S.2    Rick, F.G.3    Gorshkov, B.4    Umapathy, N.S.5    Yang, G.6
  • 47
    • 33645347065 scopus 로고    scopus 로고
    • Angiopoietin-2: Modulator of vascular permeability in acute lung injury?
    • Hashimoto T, Pittet JF. Angiopoietin-2: modulator of vascular permeability in acute lung injury? PLoS Med 2006;3:e113.
    • (2006) PLoS Med , vol.3
    • Hashimoto, T.1    Pittet, J.F.2
  • 48
    • 34848853276 scopus 로고    scopus 로고
    • Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1
    • Mei SH, McCarter SD, Deng Y, Parker CH, Liles WC, Stewart DJ. Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med 2007;4:e269.
    • (2007) PLoS Med , vol.4
    • Mei, S.H.1    McCarter, S.D.2    Deng, Y.3    Parker, C.H.4    Liles, W.C.5    Stewart, D.J.6
  • 50
    • 43549116416 scopus 로고    scopus 로고
    • Basal and angiopoietin-1–mediated endothelial permeability is regulated by sphingosine kinase-1
    • Li X, Stankovic M, Bonder CS, Hahn CN, Parsons M, Pitson SM, et al. Basal and angiopoietin-1–mediated endothelial permeability is regulated by sphingosine kinase-1. Blood 2008;111:3489–3497.
    • (2008) Blood , vol.111 , pp. 3489-3497
    • Li, X.1    Stankovic, M.2    Bonder, C.S.3    Hahn, C.N.4    Parsons, M.5    Pitson, S.M.6


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