Admixture mapping and fine-mapping of birth weight loci in the Black Women’s Health Study

Human Genetics

Volumn 137, Issue 6-7, 2018, Pages 535-542

  Ochs Balcom, Heather M ^a   Shaw, Holly ^a   Preus, Leah ^a   Palmer, Julie R ^b   Haddad, Stephen A ^b   Rosenberg, Lynn ^b   Ruiz Narváez, Edward A ^c  

^a UNIVERSITY AT BUFFALO   (United States)

^b BOSTON UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 4; HIGH MOBILITY GROUP A2 PROTEIN; ADRB1 PROTEIN, HUMAN; BETA 1 ADRENERGIC RECEPTOR; HMGA2 PROTEIN, HUMAN; SLC2A4 PROTEIN, HUMAN;

ADMIXTURE MAPPING; ADRB1 GENE; ADULT; AFRICAN; ALLELE; ARTICLE; BIRTH WEIGHT; CALCR GENE; CCNL1 GENE; CDKAL1 GENE; CENPM GENE; CLDN7 GENE; FEMALE; FINE MAPPING; GENE; GENE FREQUENCY; GENE LOCUS; GENE MAPPING; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMAN; LCORL GENE; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; AFRICAN AMERICAN; CLINICAL TRIAL; GENETICS; MIDDLE AGED; MULTICENTER STUDY;

ADULT; AFRICAN AMERICANS; BIRTH WEIGHT; FEMALE; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; GLUCOSE TRANSPORTER TYPE 4; HMGA2 PROTEIN; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ADRENERGIC, BETA-1;

EID: 85049883040     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-018-1908-x     Document Type: Article

References (40)

1. Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M et al (2018) Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet 27:742–756
2. Carty CL, Johnson NA, Hutter CM, Reiner AP, Peters U, Tang H et al (2012) Genome-wide association study of body height in African Americans: the Women’s Health Initiative SNP Health Association Resource (SHARe). Hum Mol Genet 21:711–720
3. Cirulli ET, Kasperaviciute D, Attix DK, Need AC, Ge D, Gibson G et al (2010) Common genetic variation and performance on standardized cognitive tests. Eur J Hum Genet 18:815–820
4. Cozier YC, Palmer JR, Rosenberg L (2004) Comparison of methods for collection of DNA samples by mail in the Black Women’s Health Study. Ann Epidemiol 14:117–122
5. Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ et al (2010) Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet 42:430–435
6. Gamborg M, Byberg L, Rasmussen F, Andersen PK, Baker JL, Bengtsson C et al (2007) Birth weight and systolic blood pressure in adolescence and adulthood: meta-regression analysis of sex- and age-specific results from 20 Nordic studies. Am J Epidemiol 166:634–645
7. Gao X, Starmer J, Martin ER (2008) A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genet Epidemiol 32:361–369
8. Hack M, Klein NK, Taylor HG (1995) Long-term developmental outcomes of low birth weight infants. Future Child 5:176–196
9. Hamilton BE, Martin JA, Osterman MJ, Curtin SC, Matthews TJ (2015) Births: Final Data for 2014. Natl Vital Stat Rep 64:1–64
10. He M, Xu M, Zhang B, Liang J, Chen P, Lee JY et al (2015) Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet 24:1791–1800
11. Hoggart CJ, Shriver MD, Kittles RA, Clayton DG, McKeigue PM (2004) Design and analysis of admixture mapping studies. Am J Hum Genet 74:965–978
12. Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ et al (2013) New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet 45:76–82
13. Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J et al (2016) Genome-wide associations for birth weight and correlations with adult disease. Nature 538:248–252
14. Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L et al (2011) Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals. Hypertension 57:903–910
15. Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K et al (2017) Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun 8:14977
16. Kettunen J, Tukiainen T, Sarin AP, Ortega-Alonso A, Tikkanen E, Lyytikainen LP et al (2012) Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet 44:269–276
17. Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T et al (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 46:234–244
18. Marchini J, Howie B, Myers S, McVean G, Donnelly P (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 39:906–913
19. Michels KB, Trichopoulos D, Robins JM, Rosner BA, Manson JE, Hunter DJ et al (1996) Birthweight as a risk factor for breast cancer. Lancet 348:1542–1546
20. Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, Steinthorsdottir V et al (2012) Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 44:981–990
21. Mottet F, Vardeny O, de Denus S (2016) Pharmacogenomics of heart failure: a systematic review. Pharmacogenomics 17:1817–1858
22. Mu M, Wang SF, Sheng J, Zhao Y, Li HZ, Hu CL et al (2012) Birth weight and subsequent blood pressure: a meta-analysis. Arch Cardiovasc Dis 105:99–113
23. N’Diaye A, Chen GK, Palmer CD, Ge B, Tayo B, Mathias RA et al (2011) Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet 7:e1002298
24. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N et al (1999) Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res 6:63–70
25. Ng MC, Shriner D, Chen BH, Li J, Chen WM, Guo X et al (2014) Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet 10:e1004517
26. Risnes KR, Vatten LJ, Baker JL, Jameson K, Sovio U, Kajantie E et al (2011) Birthweight and mortality in adulthood: a systematic review and meta-analysis. Int J Epidemiol 40:647–661
27. Rosenberg L, Adams-Campbell L, Palmer JR (1995) The Black Women’s Health Study: a follow-up study for causes and preventions of illness. J Am Med Womens Assoc (1972) 50:56–58
28. Ruiz-Narvaez EA, Palmer JR, Gerlovin H, Wise LA, Vimalananda VG, Rosenzweig JL et al (2014) Birth weight and risk of type 2 diabetes in the black women’s health study: does adult BMI play a mediating role? Diabetes Care 37:2572–2578
29. Sgarra R, Pegoraro S, Ros G, Penzo C, Chiefari E, Foti D et al (2018) High Mobility Group A (HMGA) proteins: molecular instigators of breast cancer onset and progression. Biochim Biophys Acta 1869:216–229
30. Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Magi R et al (2015) New genetic loci link adipose and insulin biology to body fat distribution. Nature 518:187–196
31. Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N et al (2009) Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet 5:e1000445
32. Troy LM, Michels KB, Hunter DJ, Spiegelman D, Manson JE, Colditz GA et al (1996) Self-reported birthweight and history of having been breastfed among younger women: an assessment of validity. Int J Epidemiol 25:122–127
33. Urbanek M, Hayes MG, Armstrong LL, Morrison J, Lowe LP, Badon SE et al (2013) The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study. Hum Mol Genet 22:3583–3596
34. van der Valk RJ, Kreiner-Moller E, Kooijman MN, Guxens M, Stergiakouli E, Saaf A et al (2015) A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet 24:1155–1168
35. Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP et al (2010) Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 42:579–589
36. Wang H, Liu J, Liu K, Liu Y, Wang Z, Lou Y et al (2013) beta1-adrenoceptor gene Arg389Gly polymorphism and essential hypertension risk in general population: a meta-analysis. Mol Biol Rep 40:4055–4063
37. Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B et al (2017) Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet 49:403–415
38. Weedon MN, Lettre G, Freathy RM, Lindgren CM, Voight BF, Perry JR et al (2007) A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet 39:1245–1250
39. Whincup PH, Kaye SJ, Owen CG, Huxley R, Cook DG, Anazawa S et al (2008) Birth weight and risk of type 2 diabetes: a systematic review. JAMA 300:2886–2897
40. Zhao W, Rasheed A, Tikkanen E, Lee JJ, Butterworth AS, Howson JMM et al (2017) Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. Nat Genet 49:1450–1457