-
1
-
-
84885615124
-
Acute skeletal muscle wasting in critical illness
-
Puthucheary ZA, Rawal J, McPhail M, et al. Acute skeletal muscle wasting in critical illness. JAMA 2013;310:1591-600.
-
(2013)
JAMA
, vol.310
, pp. 1591-1600
-
-
Puthucheary, Z.A.1
Rawal, J.2
McPhail, M.3
-
2
-
-
0037456354
-
One-year outcomes in survivors of the acute respiratory distress syndrome
-
Herridge MS, Cheung AM, Tansey CM, et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003;348:683-93.
-
(2003)
N Engl J Med
, vol.348
, pp. 683-693
-
-
Herridge, M.S.1
Cheung, A.M.2
Tansey, C.M.3
-
3
-
-
48249119523
-
Acquired weakness, handgrip strength, mortality in critically ill patients
-
Ali NA, O'Brien JM, Hoffmann SP, et al. Acquired weakness, handgrip strength, mortality in critically ill patients. Am J Respir Crit Care Med 2008;178:261-8.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 261-268
-
-
Ali, N.A.1
O'Brien, J.M.2
Hoffmann, S.P.3
-
4
-
-
84937485144
-
Combining nutrition and exercise to optimize survival and recovery from critical illness: Conceptual and methodological issues
-
Heyland DK, Stapleton RD, Mourtzakis M, et al. Combining nutrition and exercise to optimize survival and recovery from critical illness: Conceptual and methodological issues. Clin Nutr 2016;35:1196-206.
-
(2016)
Clin Nutr
, vol.35
, pp. 1196-1206
-
-
Heyland, D.K.1
Stapleton, R.D.2
Mourtzakis, M.3
-
5
-
-
80051648934
-
Early versus late parenteral nutrition in critically ill adults
-
Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med 2011;365:506-17.
-
(2011)
N Engl J Med
, vol.365
, pp. 506-517
-
-
Casaer, M.P.1
Mesotten, D.2
Hermans, G.3
-
6
-
-
84873108218
-
Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: A randomised controlled clinical trial
-
Heidegger CP, Berger MM, Graf S, et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: A randomised controlled clinical trial. Lancet 2013;381:385-93.
-
(2013)
Lancet
, vol.381
, pp. 385-393
-
-
Heidegger, C.P.1
Berger, M.M.2
Graf, S.3
-
7
-
-
84857427752
-
Initial trophic vs full enteral feeding in patients with acute lung injury: The EDEN randomized trial
-
Rice TW, Wheeler AP, Thompson BT, et al. Initial trophic vs full enteral feeding in patients with acute lung injury: The EDEN randomized trial. JAMA 2012;307:795-803.
-
(2012)
JAMA
, vol.307
, pp. 795-803
-
-
Rice, T.W.1
Wheeler, A.P.2
Thompson, B.T.3
-
8
-
-
84877996857
-
Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: A randomized controlled trial
-
Doig GS, Simpson F, Sweetman EA, et al. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: A randomized controlled trial. JAMA 2013;309:2130-8.
-
(2013)
JAMA
, vol.309
, pp. 2130-2138
-
-
Doig, G.S.1
Simpson, F.2
Sweetman, E.A.3
-
9
-
-
84880360244
-
Exercise rehabilitation for patients with critical illness: A randomized controlled trial with 12 months of follow-up
-
Denehy L, Skinner EH, Edbrooke L, et al. Exercise rehabilitation for patients with critical illness: A randomized controlled trial with 12 months of follow-up. Crit Care 2013;17:R156.
-
(2013)
Crit Care
, vol.17
, pp. R156
-
-
Denehy, L.1
Skinner, E.H.2
Edbrooke, L.3
-
10
-
-
84976350801
-
Standardized Rehabilitation and Hospital Length of Stay among Patients with Acute Respiratory Failure: A Randomized Clinical Trial
-
Morris PE, Berry MJ, Files DC, et al. Standardized Rehabilitation and Hospital Length of Stay Among Patients With Acute Respiratory Failure: A Randomized Clinical Trial. JAMA 2016;315:2694-702.
-
(2016)
JAMA
, vol.315
, pp. 2694-2702
-
-
Morris, P.E.1
Berry, M.J.2
Files, D.C.3
-
11
-
-
84930698195
-
Increased hospital-based physical rehabilitation and information provision after intensive care unit discharge: The RECOVER randomized clinical trial
-
Walsh TS, Salisbury LG, Merriweather JL, et al. Increased hospital-based physical rehabilitation and information provision after intensive care unit discharge: The RECOVER randomized clinical trial. JAMA Intern Med 2015;175:901-10.
-
(2015)
JAMA Intern Med
, vol.175
, pp. 901-910
-
-
Walsh, T.S.1
Salisbury, L.G.2
Merriweather, J.L.3
-
12
-
-
84976381228
-
A randomized trial of an intensive physical therapy program for patients with acute respiratory failure
-
Moss M, Nordon-Craft A, Malone D, et al. A randomized trial of an intensive physical therapy program for patients with acute respiratory failure. Am J Respir Crit Care Med 2016;193:1101-10.
-
(2016)
Am J Respir Crit Care Med
, vol.193
, pp. 1101-1110
-
-
Moss, M.1
Nordon-Craft, A.2
Malone, D.3
-
14
-
-
84952982656
-
The cost of protein production
-
Kafri M, Metzl-Raz E, Jona G, et al. The cost of protein production. Cell Rep 2016;14:22-31.
-
(2016)
Cell Rep
, vol.14
, pp. 22-31
-
-
Kafri, M.1
Metzl-Raz, E.2
Jona, G.3
-
15
-
-
0037142987
-
Association between mitochondrial dysfunction and severity and outcome of septic shock
-
Brealey D, Brand M, Hargreaves I, et al. Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 2002;360:219-23.
-
(2002)
Lancet
, vol.360
, pp. 219-223
-
-
Brealey, D.1
Brand, M.2
Hargreaves, I.3
-
16
-
-
33751186701
-
Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure
-
Fredriksson K, Hammarqvist F, Strigård K, et al. Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure. Am J Physiol Endocrinol Metab 2006;291:E1044-E1050.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, pp. E1044-E1050
-
-
Fredriksson, K.1
Hammarqvist, F.2
Strigård, K.3
-
17
-
-
84877910281
-
Supplemental parenteral nutrition in critically ill patients
-
Casaer MP, Wilmer A, Van den Berghe G. Supplemental parenteral nutrition in critically ill patients. Lancet 2013;381:1715.
-
(2013)
Lancet
, vol.381
, pp. 1715
-
-
Casaer, M.P.1
Wilmer, A.2
Van Den Berghe, G.3
-
19
-
-
85054471634
-
Sepsis oxidative stress hypoxia: Are there clues to better treatment
-
RER11325
-
Bar-Or D, Carrick MM, Mains CW, et al. Sepsis, oxidative stress, hypoxia: Are there clues to better treatment? Redox Rep 2015;20:193-7. RER11325.
-
(2015)
Redox Rep
, vol.20
, pp. 193-197
-
-
Bar-Or, D.1
Carrick, M.M.2
Mains, C.W.3
-
20
-
-
34548154784
-
The prognostic value of muscle StO2 in septic patients
-
Creteur J, Carollo T, Soldati G, et al. The prognostic value of muscle StO2 in septic patients. Intensive Care Med 2007;33:1549-56.
-
(2007)
Intensive Care Med
, vol.33
, pp. 1549-1556
-
-
Creteur, J.1
Carollo, T.2
Soldati, G.3
-
21
-
-
33646550165
-
Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells
-
Connolly E, Braunstein S, Formenti S, et al. Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol Cell Biol 2006;26:3955-65.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3955-3965
-
-
Connolly, E.1
Braunstein, S.2
Formenti, S.3
-
22
-
-
77953202236
-
Low-dose dexamethasone prevents endotoxaemia-induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle
-
Crossland H, Constantin-Teodosiu D, Greenhaff PL, et al. Low-dose dexamethasone prevents endotoxaemia-induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle. J Physiol 2010;588(Pt 8):1333-47.
-
(2010)
J Physiol
, vol.588
, pp. 1333-1347
-
-
Crossland, H.1
Constantin-Teodosiu, D.2
Greenhaff, P.L.3
-
24
-
-
77957041807
-
Survival in critical illness is associated with early activation of mitochondrial biogenesis
-
Carré JE, Orban JC, Re L, et al. Survival in critical illness is associated with early activation of mitochondrial biogenesis. Am J Respir Crit Care Med 2010;182:745-51.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 745-751
-
-
Carré, J.E.1
Orban, J.C.2
Re, L.3
-
25
-
-
0016199722
-
Glycogen glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values
-
Harris RC, Hultman E, Nordesjö LO. Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand J Clin Lab Invest 1974;33:109-20.
-
(1974)
Scand J Clin Lab Invest
, vol.33
, pp. 109-120
-
-
Harris, R.C.1
Hultman, E.2
Nordesjö, L.O.3
-
26
-
-
84946215312
-
Optimization of metabolite extraction of human vein tissue for ultra performance liquid chromatography-mass spectrometry and nuclear magnetic resonance-based untargeted metabolic profiling
-
Anwar MA, Vorkas PA, Li JV, et al. Optimization of metabolite extraction of human vein tissue for ultra performance liquid chromatography-mass spectrometry and nuclear magnetic resonance-based untargeted metabolic profiling. Analyst 2015;140:7586-97.
-
(2015)
Analyst
, vol.140
, pp. 7586-7597
-
-
Anwar, M.A.1
Vorkas, P.A.2
Li, J.V.3
-
27
-
-
84872225149
-
PGC1and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders
-
Austin S, St-Pierre J. PGC1and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders. J Cell Sci 2012;125(Pt 21):4963-71.
-
(2012)
J Cell Sci
, vol.125
, pp. 4963-4971
-
-
Austin, S.1
St-Pierre, J.2
-
28
-
-
84889242417
-
Mitochondrial dynamics-mitochondrial fission and fusion in human diseases
-
Archer SL. Mitochondrial dynamics-mitochondrial fission and fusion in human diseases. N Engl J Med 2013;369:2236-51.
-
(2013)
N Engl J Med
, vol.369
, pp. 2236-2251
-
-
Archer, S.L.1
-
29
-
-
0035998835
-
Model-based clustering, discriminant analysis and density estimation
-
CFaAE R. Model-based clustering, discriminant analysis and density estimation. Journal of the American Statistical Association 2002;97:611-31.
-
(2002)
Journal of the American Statistical Association
, vol.97
, pp. 611-631
-
-
Cfaae, R.1
-
30
-
-
0242490780
-
Cytoscape: A software environment for integrated models of biomolecular interaction networks
-
Shannon P, Markiel A, Ozier O, et al. Cytoscape: A software environment for integrated models of biomolecular interaction networks. Genome Res 2003;13:2498-504.
-
(2003)
Genome Res
, vol.13
, pp. 2498-2504
-
-
Shannon, P.1
Markiel, A.2
Ozier, O.3
-
31
-
-
84962529612
-
The enduring evolution of the P value
-
Kyriacou DN. The enduring evolution of the P value. JAMA 2016;315:1113-5.
-
(2016)
JAMA
, vol.315
, pp. 1113-1115
-
-
Kyriacou, D.N.1
-
32
-
-
79960831814
-
Novel events in the molecular regulation of muscle mass in critically ill patients
-
Constantin D, McCullough J, Mahajan RP, et al. Novel events in the molecular regulation of muscle mass in critically ill patients. J Physiol 2011;589(Pt 15):3883-95.
-
(2011)
J Physiol
, vol.589
, pp. 3883-3895
-
-
Constantin, D.1
McCullough, J.2
Mahajan, R.P.3
-
33
-
-
56449103294
-
A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle
-
Crossland H, Constantin-Teodosiu D, Gardiner SM, et al. A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. J Physiol 2008;586(22):5589-600.
-
(2008)
J Physiol
, vol.586
, Issue.22
, pp. 5589-5600
-
-
Crossland, H.1
Constantin-Teodosiu, D.2
Gardiner, S.M.3
-
34
-
-
84941320735
-
Qualitative ultrasound in acute critical illness muscle wasting
-
Puthucheary ZA, Phadke R, Rawal J, et al. Qualitative ultrasound in acute critical illness muscle wasting. Crit Care Med 2015;43:1603-11.
-
(2015)
Crit Care Med
, vol.43
, pp. 1603-1611
-
-
Puthucheary, Z.A.1
Phadke, R.2
Rawal, J.3
-
35
-
-
78751682676
-
Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype
-
Villalta SA, Rinaldi C, Deng B, et al. Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype. Hum Mol Genet 2011;20:790-805.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 790-805
-
-
Villalta, S.A.1
Rinaldi, C.2
Deng, B.3
-
36
-
-
80052761810
-
Macrophage polarization in metabolic disorders: Functions and regulation
-
Chinetti-Gbaguidi G, Staels B. Macrophage polarization in metabolic disorders: Functions and regulation. Curr Opin Lipidol 2011;22:365-72.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 365-372
-
-
Chinetti-Gbaguidi, G.1
Staels, B.2
-
37
-
-
79953875974
-
Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients
-
Vanhorebeek I, Gunst J, Derde S, et al. Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab 2011;96:E633-E645.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. E633-E645
-
-
Vanhorebeek, I.1
Gunst, J.2
Derde, S.3
-
38
-
-
84866551217
-
IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration
-
Deng B, Wehling-Henricks M, Villalta SA, et al. IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration. J Immunol 2012;189:3669-80.
-
(2012)
J Immunol
, vol.189
, pp. 3669-3680
-
-
Deng, B.1
Wehling-Henricks, M.2
Villalta, S.A.3
-
41
-
-
84867660436
-
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
-
De Saedeleer CJ, Copetti T, Porporato PE, et al. Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells. PLoS One 2012;7:e46571.
-
(2012)
PLoS One
, vol.7
, pp. e46571
-
-
De Saedeleer, C.J.1
Copetti, T.2
Porporato, P.E.3
-
43
-
-
0035027828
-
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells
-
Seagroves TN, Ryan HE, Lu H, et al. Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. Mol Cell Biol 2001;21:3436-44.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3436-3444
-
-
Seagroves, T.N.1
Ryan, H.E.2
Lu, H.3
-
44
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001;7:941-6.
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
-
45
-
-
2442419837
-
Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells
-
Li WG, Gavrila D, Liu X, et al. Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells. Circulation 2004;109:2221-6.
-
(2004)
Circulation
, vol.109
, pp. 2221-2226
-
-
Li, W.G.1
Gavrila, D.2
Liu, X.3
-
46
-
-
33947627537
-
Adiponectin as an anti-inflammatory factor
-
Ouchi N, Walsh K. Adiponectin as an anti-inflammatory factor. Clin Chim Acta 2007;380:24-30.
-
(2007)
Clin Chim Acta
, vol.380
, pp. 24-30
-
-
Ouchi, N.1
Walsh, K.2
-
48
-
-
85054486748
-
-
N utrition A. Secondary. https://www. abbottnutrition. co. uk/products-A nd-services/Abbott-Nutrition-Products/jevity-plus.
-
N Utrition A Secondary
-
-
-
49
-
-
85054498805
-
-
Kabiven. Secondary. 2014. http://www. kabivenusa. com/pdf/Kabiven-PI.pdf
-
(2014)
Kabiven. Secondary
-
-
-
50
-
-
81055149825
-
Identifying critically ill patients who benefit the most from nutrition therapy: The development and initial validation of a novel risk assessment tool
-
Heyland DK, Dhaliwal R, Jiang X, et al. Identifying critically ill patients who benefit the most from nutrition therapy: The development and initial validation of a novel risk assessment tool. Crit Care 2011;15:R268.
-
(2011)
Crit Care
, vol.15
, pp. R268
-
-
Heyland, D.K.1
Dhaliwal, R.2
Jiang, X.3
-
51
-
-
84954285942
-
Gene expression profiling of asthma phenotypes demonstrates molecular signatures of atopy and asthma control
-
Howrylak JA, Moll M, Weiss ST, et al. Gene expression profiling of asthma phenotypes demonstrates molecular signatures of atopy and asthma control. J Allergy Clin Immunol 2016;137:1390-7.
-
(2016)
J Allergy Clin Immunol
, vol.137
, pp. 1390-1397
-
-
Howrylak, J.A.1
Moll, M.2
Weiss, S.T.3
-
52
-
-
84984697640
-
70-Gene signature as an aid to treatment decisions in early-stage breast cancer
-
Cardoso F, van't Veer LJ, Bogaerts J, et al. 70-Gene signature as an aid to treatment decisions in early-stage breast cancer. N Engl J Med 2016;375:717-29.
-
(2016)
N Engl J Med
, vol.375
, pp. 717-729
-
-
Cardoso, F.1
Van'T Veer, L.J.2
Bogaerts, J.3
-
53
-
-
0035130102
-
Diseases of liporegulation: New perspective on obesity and related disorders
-
Unger RH, Orci L. Diseases of liporegulation: New perspective on obesity and related disorders. Faseb J 2001;15:312-21.
-
(2001)
Faseb J
, vol.15
, pp. 312-321
-
-
Unger, R.H.1
Orci, L.2
-
54
-
-
84938517190
-
Exercise interventions in critical illness survivors: Understanding inclusion and stratification Criteria
-
Puthucheary ZA, Denehy L. Exercise Interventions in Critical Illness Survivors: Understanding Inclusion and Stratification Criteria. Am J Respir Crit Care Med 2015;191:1464-7.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 1464-1467
-
-
Puthucheary, Z.A.1
Denehy, L.2
-
55
-
-
84864841966
-
Cryopreservation of human skeletal muscle impairs mitochondrial function
-
Larsen S, Wright-Paradis C, Gnaiger E, et al. Cryopreservation of human skeletal muscle impairs mitochondrial function. Cryo Letters 2012;33:170-6.
-
(2012)
Cryo Letters
, vol.33
, pp. 170-176
-
-
Larsen, S.1
Wright-Paradis, C.2
Gnaiger, E.3
-
56
-
-
84897032415
-
Cryopreservation with dimethyl sulfoxide prevents accurate analysis of skinned skeletal muscle fibers mitochondrial respiration
-
Meyer A, Charles AL, Zoll J, et al. Cryopreservation with dimethyl sulfoxide prevents accurate analysis of skinned skeletal muscle fibers mitochondrial respiration. Biochimie 2014;100:227-33.
-
(2014)
Biochimie
, vol.100
, pp. 227-233
-
-
Meyer, A.1
Charles, A.L.2
Zoll, J.3
-
57
-
-
0022542572
-
Effects of delayed freezing on content of phosphagens in human skeletal muscle biopsy samples
-
Söderlund K, Hultman E. Effects of delayed freezing on content of phosphagens in human skeletal muscle biopsy samples. J Appl Physiol 1986;61:832-5.
-
(1986)
J Appl Physiol
, vol.61
, pp. 832-835
-
-
Söderlund, K.1
Hultman, E.2
-
59
-
-
84941315884
-
Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function
-
Parry SM, El-Ansary D, Cartwright MS, et al. Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function. J Crit Care 2015;30:1151.e9-1151.e14.
-
(2015)
J Crit Care
, vol.30
, pp. 1151e9-1151e14
-
-
Parry, S.M.1
El-Ansary, D.2
Cartwright, M.S.3
-
60
-
-
85008700660
-
Rectus femoris cross-sectional area and muscle layer thickness: Comparative markers of muscle wasting and weakness
-
Puthucheary ZA, McNelly AS, Rawal J, et al. Rectus femoris cross-sectional area and muscle layer thickness: Comparative markers of muscle wasting and weakness. Am J Respir Crit Care Med 2017;195:136-8
-
(2017)
Am J Respir Crit Care Med
, vol.195
, pp. 136-138
-
-
Puthucheary, Z.A.1
McNelly, A.S.2
Rawal, J.3
-
61
-
-
84878809129
-
Principled missing data methods for researchers
-
Dong Y, Peng CY. Principled missing data methods for researchers. Springerplus 2013;2:222.
-
(2013)
Springerplus
, vol.2
, pp. 222
-
-
Dong, Y.1
Peng, C.Y.2
|