Whole-Genome sequencing of pharmacogenetic drug response in racially diverse children with asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 197, Issue 12, 2018, Pages 1552-1564

  Mak, Angel C Y ^a   White, Marquitta J ^a   Eckalbar, Walter L ^a   Szpiech, Zachary A ^b   Oh, Sam S ^a   Pino Yanes, Maria ^b,c   Hu, Donglei ^a   Goddard, Paǵe ^a   Huntsman, Scott ^a   Galanter, Joshua ^a,ad   Chen Wu, Ann ^d,e   Himes, Blanca E ^f,v   Germer, Soren ^g   Vogel, Julia M ^g,af   Bunting, Karen L ^g   Eng, Celeste ^a   Salazar, Sandra ^a   Keys, Kevin L ^a   Liberto, Jennifer ^a   Nuckton, Thomas J ^a   Nguyen, Thomas A ^a   Torgerson, Dara G ^h   Kwok, Pui Yan ^b,i   Levin, Albert M ^j   Celedón, Juan C ^k   Forno, Erick ^k   Hakonarson, Hakon ^b   Sleiman, Patrick M ^b   Dahlin, Amber ^d   Tantisira, Kelan G ^d,ae   Weiss, Scott T ^d   Serebrisky, Denise ^l   Brigino Buenaventura, Emerita ^m   Farber, Harold J ⁿ   Meade, Kelley ^o   Lenoir, Michael A ^p   Avila, Pedro C ^q   Sen, Saunak ^a,ag   Thyne, Shannon M ^r   Rodriguez Cintron, William ^s   Winkler, Cheryl A ^t   Moreno Estrada, Andŕes ^u   Sandoval, Karla ^u   Rodriguez Santana, Jose R ^v   Kumar, Rajesh ^w,x   Keoki Williams, L ^b,h,t   Ahituv, Nadav ^b,y   Ziv, Elad ^a   Seibold, Max A ^z   Darnell, Robert B ^g,aa,ab   Zaitlen, Noah ^a   Hernandez, Ryan D ^b,i,ac   Burchard, Esteban G ^a,b   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Bioengineering and Therapeutic Sciences ^*  (United States)

^c Cardiovascular Research Institute   (United States)

^d Institute for Human Genetics   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA   (Spain)

^g INSTITUTO DE SALUD CARLOS III   (Spain)

^h BRIGHAM AND WOMEN S HOSPITAL   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j UNIVERSITY OF PENNSYLVANIA   (United States)

^k NEW YORK GENOME CENTER   (United States)

^l HENRY FORD HEALTH SYSTEM   (United States)

^m UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

ⁿ CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^o JACOBI MEDICAL CENTER   (United States)

^p KAISER PERMANENTE   (United States)

^q BAYLOR COLLEGE OF MEDICINE   (United States)

^r CHILDREN S HOSPITAL OAKLAND   (United States)

^s Bay Area Pediatrics   (United States)

^t NORTHWESTERN UNIVERSITY   (United States)

^u UNIVERSITY OF CALIFORNIA   (United States)

^v VA Caribbean Healthcare System Puerto Rico   (Puerto Rico)

^w NATIONAL CANCER INSTITUTE   (United States)

^x DEPARTAMENTO DE FÍSICA   (Mexico)

^y Centro de Neumolo ia Pediatrica   (Puerto Rico)

^z CHILDREN'S MEMORIAL HOSPITAL   (United States)

^aa UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^ab Laboratory of Molecular Neuro oncology   (United States)

^ac ROCKEFELLER UNIVERSITY   (United States)

^ad GENENTECH INC   (United States)

^ae SCRIPPS RESEARCH INSTITUTE   (United States)

^af Allergy and ENT Assoc Woodlands   (United States)

^ag UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

more..

Author keywords

Albuterol; Asthma; Latinos; Minority; NFKB1

Indexed keywords

ADAMTS3 PROTEIN; BRONCHODILATING AGENT; CYCLOOXYGENASE 18; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLCB1 PROTEIN; PROTEIN; SALBUTAMOL; SLC39A8 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; BRONCHODILATATION; BRONCHUS MUSCLE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG RESPONSE; EXPRESSION QUANTITATIVE TRAIT LOCUS; FALSE NEGATIVE RESULT; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HUMAN; IMMUNE RESPONSE; LUNG CAPACITY; MAJOR CLINICAL STUDY; PERSONALIZED MEDICINE; PHARMACOGENETICS; POPULATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE GENOME SEQUENCING; ADOLESCENT; AFRICAN AMERICAN; COMPARATIVE STUDY; FEMALE; GENETICS; HISPANIC; MALE; MEXICAN AMERICAN; PHARMACOGENETIC VARIANT; UNITED STATES;

ADOLESCENT; AFRICAN AMERICANS; ALBUTEROL; ASTHMA; BRONCHODILATOR AGENTS; CHILD; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HISPANIC AMERICANS; HUMANS; MALE; MEXICAN AMERICANS; PHARMACOGENOMIC VARIANTS; POLYMORPHISM, SINGLE NUCLEOTIDE; RACE FACTORS; UNITED STATES;

EID: 85049056102     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201712-2529OC     Document Type: Article

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