Modeling and simulation analysis of propyl-thiouracil (PTU), an anti-thyroid drug on thyroid peroxidase (TPO), thyroid stimulating hormone receptor (TSHR), and sodium iodide (NIS) symporter based on systems biology approach

Network Modeling and Analysis in Health Informatics and Bioinformatics

Volumn 2, Issue 1, 2013, Pages 45-57

  Gupta, Manish Kumar ^a   Misra, Krishna ^b  

^a CSJM UNIVERSITY   (India)

^b SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Integrated pathways; Metabolic modeling; Simulation; Systems biology

Indexed keywords

COMPLEX NETWORKS; ENDOCRINOLOGY; HORMONES; INTEGRAL EQUATIONS; IODINE COMPOUNDS; METABOLISM; PHYSIOLOGY;

COMPUTATIONAL MODEL; INTEGRATED PATHWAYS; METABOLIC MODELING; MODEL AND SIMULATION; SIMULATION; SYSTEMS BIOLOGY; THERAPEUTIC TARGETS; THYROID STIMULATING HORMONES;

SODIUM IODIDE;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LEPTIN; LIOTHYRONINE; PROPYLTHIOURACIL; SODIUM IODIDE; THYROID PEROXIDASE; THYROTROPIN RECEPTOR; THYROXINE;

ARTICLE; COMPUTER MODEL; DRUG ACTIVITY; ENZYME KINETICS; GENE EXPRESSION; GENE REGULATORY NETWORK; HILL REACTION; PRIORITY JOURNAL; SIMULATION; SYSTEMS BIOLOGY; THYROID HORMONE RELEASE;

EID: 85048746506     PISSN: None     EISSN: 21926670     Source Type: Journal    
DOI: 10.1007/s13721-013-0023-0     Document Type: Article

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