Grifolic acid induces GH3 adenoma cell death by inhibiting ATP production through a GPR120-independent mechanism

BMC Pharmacology and Toxicology

Volumn 19, Issue 1, 2018, Pages

  Zhao, Yufeng ^a   Zhang, Lei ^a   Yan, Aili ^a   Chen, Di ^a   Xie, Rong ^a   Liu, Yingguang ^a   Liang, Xiangyan ^a   Zhao, Yanyan ^a   Wei, Lanlan ^a   Yu, Jun ^a   Xu, Xi ^a   Su, Xingli ^a  

^a XI'AN MEDICAL UNIVERSITY   (China)

Author keywords

Cell death; GH3 cells; Grifolic acid; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; G PROTEIN COUPLED RECEPTOR 120; GRIFOLIC ACID; ICOSAPENTAENOIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; O3FAR1 PROTEIN, RAT; SESTERTERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LEVEL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; GH3 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; TIME; ADENOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DEATH; DRUG EFFECT; GENETICS; METABOLISM; RAT; TUMOR CELL LINE;

ADENOMA; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; MEMBRANE POTENTIAL, MITOCHONDRIAL; RATS; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SESTERTERPENES;

EID: 85047723775     PISSN: None     EISSN: 20506511     Source Type: Journal    
DOI: 10.1186/s40360-018-0215-4     Document Type: Article

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