-
1
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science. 2006;313:1960-1964.
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
-
2
-
-
29144514645
-
Effector memory T cells, early metastasis, and survival in colorectal cancer
-
Pages F, Berger A, Camus M, et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med. 2005;353:2654-2666.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 2654-2666
-
-
Pages, F.1
Berger, A.2
Camus, M.3
-
3
-
-
0035818515
-
Frameshiftmutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer
-
Saeterdal I, Bjorheim J, Lislerud K, et al. Frameshiftmutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer. Proc Natl Acad Sci U S A. 2001;98:13255-13260.
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, pp. 13255-13260
-
-
Saeterdal, I.1
Bjorheim, J.2
Lislerud, K.3
-
4
-
-
33751339780
-
Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ
-
discussion 992-983
-
Koch M, Beckhove P, Op den Winkel J, et al. Tumor infiltrating T lymphocytes in colorectal cancer: tumor-selective activation and cytotoxic activity in situ. Ann Surg. 2006;244:986-992; discussion 992-983.
-
(2006)
Ann. Surg.
, vol.244
, pp. 986-992
-
-
Koch, M.1
Beckhove, P.2
Winkel, O.D.J.3
-
5
-
-
4444243096
-
Tumor-specific shared antigenic peptides recognized by human T cells
-
Van der Bruggen P, Zhang Y, Chaux P, et al. Tumor-specific shared antigenic peptides recognized by human T cells. Immunol Rev. 2002;188:51-64.
-
(2002)
Immunol. Rev.
, vol.188
, pp. 51-64
-
-
Van Der Bruggen, P.1
Zhang, Y.2
Chaux, P.3
-
6
-
-
0033057177
-
The carcinoembryonic antigen (CEA) family: Structures, suggested functions and expression in normal and malignant tissues
-
Hammarstrom S. The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Semin Cancer Biol. 1999;9:67-81.
-
(1999)
Semin. Cancer Biol.
, vol.9
, pp. 67-81
-
-
Hammarstrom, S.1
-
7
-
-
33846657219
-
Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers
-
Blumenthal RD, Leon E, Hansen HJ, et al. Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers. BMC Cancer. 2007;7:2.
-
(2007)
BMC Cancer
, vol.7
, pp. 2
-
-
Blumenthal, R.D.1
Leon, E.2
Hansen, H.J.3
-
8
-
-
0029042336
-
Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine
-
Tsang KY, Zaremba S, Nieroda CA, et al. Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine. J Natl Cancer Inst. 1995;87:982-990.
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 982-990
-
-
Tsang, K.Y.1
Zaremba, S.2
Nieroda, C.A.3
-
9
-
-
0030882684
-
Identification of an enhancer agonist cytotoxic T lymphocyte peptide from human carcinoembryonic antigen
-
Zaremba S, Barzaga E, Zhu M, et al. Identification of an enhancer agonist cytotoxic T lymphocyte peptide from human carcinoembryonic antigen. Cancer Res. 1997;57:4570-4577.
-
(1997)
Cancer Res.
, vol.57
, pp. 4570-4577
-
-
Zaremba, S.1
Barzaga, E.2
Zhu, M.3
-
10
-
-
0037089660
-
Carcinoembryonic antigen as a target for therapeutic anticancer vaccines: A review
-
Berinstein NL. Carcinoembryonic antigen as a target for therapeutic anticancer vaccines: a review. J Clin Oncol. 2002;20:2197-2207.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2197-2207
-
-
Berinstein, N.L.1
-
11
-
-
22144433725
-
Towards therapeutic vaccines for colorectal carcinoma: A review of clinical trials
-
Mosolits S, Nilsson B, Mellstedt H. Towards therapeutic vaccines for colorectal carcinoma: a review of clinical trials. Expert Rev Vaccines. 2005;4:329-350.
-
(2005)
Expert Rev. Vaccines
, vol.4
, pp. 329-350
-
-
Mosolits, S.1
Nilsson, B.2
Mellstedt, H.3
-
12
-
-
0035902607
-
Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy
-
Fong L, Hou Y, Rivas A, et al. Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy. Proc Natl Acad Sci U S A. 2001;98:8809-8814.
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, pp. 8809-8814
-
-
Fong, L.1
Hou, Y.2
Rivas, A.3
-
13
-
-
50949115267
-
Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines
-
Morse MA, Hobeika AC, Osada T, et al. Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines. Blood. 2008;112:610-618.
-
(2008)
Blood
, vol.112
, pp. 610-618
-
-
Morse, M.A.1
Hobeika, A.C.2
Osada, T.3
-
14
-
-
0034092701
-
Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells
-
Latouche JB, Sadelain M. Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells. Nat Biotechnol. 2000;18:405-409.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 405-409
-
-
Latouche, J.B.1
Sadelain, M.2
-
15
-
-
0141593507
-
Rapid expansion of cytomegalovirus-specific cytotoxic T lymphocytes by artificial antigen-presenting cells expressing a single HLA allele
-
Papanicolaou GA, Latouche JB, Tan C, et al. Rapid expansion of cytomegalovirus-specific cytotoxic T lymphocytes by artificial antigen-presenting cells expressing a single HLA allele. Blood. 2003;102:2498-2505.
-
(2003)
Blood
, vol.102
, pp. 2498-2505
-
-
Papanicolaou, G.A.1
Latouche, J.B.2
Tan, C.3
-
16
-
-
20444498276
-
Artificial antigen-presenting cells transduced with telomerase efficiently expand epitopespecific, human leukocyte antigen-restricted cytotoxic T cells
-
Dupont J, Latouche JB, Ma C, et al. Artificial antigen-presenting cells transduced with telomerase efficiently expand epitopespecific, human leukocyte antigen-restricted cytotoxic T cells. Cancer Res. 2005;65:5417-5427.
-
(2005)
Cancer Res.
, vol.65
, pp. 5417-5427
-
-
Dupont, J.1
Latouche, J.B.2
Ma, C.3
-
17
-
-
0033571120
-
A triad of costimulatory molecules synergize to amplify T-cell activation
-
Hodge JW, Sabzevari H, Yafal AG, et al. A triad of costimulatory molecules synergize to amplify T-cell activation. Cancer Res. 1999;59:5800-5807.
-
(1999)
Cancer Res.
, vol.59
, pp. 5800-5807
-
-
Hodge, J.W.1
Sabzevari, H.2
Yafal, A.G.3
-
18
-
-
0035328585
-
Enhanced activation of human T cells via avipox vector-mediated hyperexpression of a triad of costimulatory molecules in human dendritic cells
-
Zhu M, Terasawa H, Gulley J, et al. Enhanced activation of human T cells via avipox vector-mediated hyperexpression of a triad of costimulatory molecules in human dendritic cells. Cancer Res. 2001;61:3725-3734.
-
(2001)
Cancer Res.
, vol.61
, pp. 3725-3734
-
-
Zhu, M.1
Terasawa, H.2
Gulley, J.3
-
19
-
-
0029862497
-
A stable humanderived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
-
Ory DS, Neugeboren BA, Mulligan RC. A stable humanderived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci U S A. 1996;93:11400-11406.
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 11400-11406
-
-
Ory, D.S.1
Neugeboren, B.A.2
Mulligan, R.C.3
-
20
-
-
34848927210
-
Low TCR avidity and lack of tumor cell recognition in CD8 (+) T cells primed with the CEA-analogue CAP1-6D peptide
-
Iero M, Squarcina P, Romero P, et al. Low TCR avidity and lack of tumor cell recognition in CD8 (+) T cells primed with the CEA-analogue CAP1-6D peptide. Cancer Immunol Immunother. 2007;56:1979-1991.
-
(2007)
Cancer Immunol. Immunother.
, vol.56
, pp. 1979-1991
-
-
Iero, M.1
Squarcina, P.2
Romero, P.3
-
21
-
-
0031065147
-
Optimal T cell activation by melanoma cells depends on a minimal level of antigen transcription
-
Labarriere N, Diez E, Pandolfino MC, et al. Optimal T cell activation by melanoma cells depends on a minimal level of antigen transcription. J Immunol. 1997;158:1238-1245.
-
(1997)
J. Immunol.
, vol.158
, pp. 1238-1245
-
-
Labarriere, N.1
Diez, E.2
Pandolfino, M.C.3
-
22
-
-
0029164582
-
Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells
-
Riviere I, Brose K, Mulligan RC. Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proc Natl Acad Sci U S A. 1995;92:6733-6737.
-
(1995)
Proc. Natl. Acad. Sci. U S A
, vol.92
, pp. 6733-6737
-
-
Riviere, I.1
Brose, K.2
Mulligan, R.C.3
-
23
-
-
0030815408
-
The internal ribosomal entry site of the encephalomyocarditis virus enables reliable coexpression of two transgenes in human primary T lymphocytes
-
Gallardo HF, Tan C, Sadelain M. The internal ribosomal entry site of the encephalomyocarditis virus enables reliable coexpression of two transgenes in human primary T lymphocytes. Gene Ther. 1997;4:1115-1119.
-
(1997)
Gene Ther.
, vol.4
, pp. 1115-1119
-
-
Gallardo, H.F.1
Tan, C.2
Sadelain, M.3
-
24
-
-
0002613687
-
Methods for the construction of retroviral vectors and the generation of high-titer producers
-
Robbins PD, ed, Totowa, NJ: Humana Press
-
Riviere I, Sadelain M. Methods for the construction of retroviral vectors and the generation of high-titer producers. In: Robbins PD, ed. Gene Therapy Protocols. Totowa, NJ: Humana Press; 1997:59-78.
-
(1997)
Gene Therapy Protocols
, pp. 59-78
-
-
Riviere, I.1
Sadelain, M.2
-
25
-
-
0025318137
-
Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells
-
Young JW, Steinman RM. Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells. J Exp Med. 1990;171:1315-1332.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 1315-1332
-
-
Young, J.W.1
Steinman, R.M.2
-
26
-
-
0029895748
-
Suboptimal activation of melanoma infiltrating lymphocytes (TIL) due to low avidity of TCR/MHC-tumor peptide interactions
-
Gervois N, Guilloux Y, Diez E, et al. Suboptimal activation of melanoma infiltrating lymphocytes (TIL) due to low avidity of TCR/MHC-tumor peptide interactions. J Exp Med. 1996;183:2403-2407.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2403-2407
-
-
Gervois, N.1
Guilloux, Y.2
Diez, E.3
-
27
-
-
33749000327
-
Immunomodulatory roles of the carcinoembryonic antigen family of glycoproteins
-
Shao L, Allez M, Park MS, et al. Immunomodulatory roles of the carcinoembryonic antigen family of glycoproteins. Ann N Y Acad Sci. 2006;1072:194-209.
-
(2006)
Ann. N. Y Acad. Sci.
, vol.1072
, pp. 194-209
-
-
Shao, L.1
Allez, M.2
Park, M.S.3
-
28
-
-
0033847263
-
Identification of tumorassociated MHC class I ligands by a novel T cell-independent approach
-
Schirle M, Keilholz W, Weber B, et al. Identification of tumorassociated MHC class I ligands by a novel T cell-independent approach. Eur J Immunol. 2000;30:2216-2225.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2216-2225
-
-
Schirle, M.1
Keilholz, W.2
Weber, B.3
-
29
-
-
40749161930
-
Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen
-
Hou Y, Kavanagh B, Fong L. Distinct CD8+ T cell repertoires primed with agonist and native peptides derived from a tumor-associated antigen. J Immunol. 2008;180:1526-1534.
-
(2008)
J. Immunol.
, vol.180
, pp. 1526-1534
-
-
Hou, Y.1
Kavanagh, B.2
Fong, L.3
-
30
-
-
0034012202
-
Agonist peptide from a cytotoxic t-lymphocyte epitope of human carcinoembryonic antigen stimulates production of tc1-type cytokines and increases tyrosine phosphorylation more efficiently than cognate peptide
-
Salazar E, Zaremba S, Arlen PM, et al. Agonist peptide from a cytotoxic t-lymphocyte epitope of human carcinoembryonic antigen stimulates production of tc1-type cytokines and increases tyrosine phosphorylation more efficiently than cognate peptide. Int J Cancer. 2000;85:829-838.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 829-838
-
-
Salazar, E.1
Zaremba, S.2
Arlen, P.M.3
-
31
-
-
26444556446
-
Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA
-
Mennuni C, Calvaruso F, Facciabene A, et al. Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA. Int J Cancer. 2005;117:444-455.
-
(2005)
Int. J. Cancer
, vol.117
, pp. 444-455
-
-
Mennuni, C.1
Calvaruso, F.2
Facciabene, A.3
-
32
-
-
68449088812
-
A novel mouse model for evaluation and prediction of HLA-A2-restricted CEA cancer vaccine responses
-
Conforti A, Peruzzi D, Giannetti P, et al. A novel mouse model for evaluation and prediction of HLA-A2-restricted CEA cancer vaccine responses. J Immunother. 2009;32:744-754.
-
(2009)
J. Immunother.
, vol.32
, pp. 744-754
-
-
Conforti, A.1
Peruzzi, D.2
Giannetti, P.3
-
33
-
-
58849160937
-
Characterization of genetically modified T-cell receptors that recognize the CEA: 691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells
-
Parkhurst MR, Joo J, Riley JP, et al. Characterization of genetically modified T-cell receptors that recognize the CEA: 691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells. Clin Cancer Res. 2009;15:169-180.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 169-180
-
-
Parkhurst, M.R.1
Joo, J.2
Riley, J.P.3
-
34
-
-
0031960397
-
Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
-
DOI 10.1038/nbt0498-364
-
Nair SK, Boczkowski D, Morse M, et al. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat Biotechnol. 1998;16:364-369. (Pubitemid 28164657)
-
(1998)
Nature Biotechnology
, vol.16
, Issue.4
, pp. 364-369
-
-
Nair, S.K.1
Boczkowski, D.2
Morse, M.3
Cumming, R.I.4
Lyerly, H.K.5
Gilboa, E.6
-
35
-
-
3543034678
-
Effect of prolactin on carcinoembryonic antigen-specific cytotoxic T lymphocyte response induced by dendritic cells
-
Matera L, Beltramo E, Martinuzzi E, et al. Effect of prolactin on carcinoembryonic antigen-specific cytotoxic T lymphocyte response induced by dendritic cells. Clin Exp Immunol. 2004;137:320-328.
-
(2004)
Clin. Exp. Immunol.
, vol.137
, pp. 320-328
-
-
Matera, L.1
Beltramo, E.2
Martinuzzi, E.3
-
36
-
-
0031962868
-
Dendritic cells pulsed with CEA peptide induce CEA-specific CTL with restricted TCR repertoire
-
Alters SE, Gadea JR, Sorich M, et al. Dendritic cells pulsed with CEA peptide induce CEA-specific CTL with restricted TCR repertoire. J Immunother. 1998;21:17-26.
-
(1998)
J. Immunother.
, vol.21
, pp. 17-26
-
-
Alters, S.E.1
Gadea, J.R.2
Sorich, M.3
-
37
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature. 1998;392:245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
38
-
-
0031937298
-
The multi-epitope approach for immunotherapy for cancer: Identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors
-
Kawashima I, Hudson SJ, Tsai V, et al. The multi-epitope approach for immunotherapy for cancer: identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors. Hum Immunol. 1998;59:1-14.
-
(1998)
Hum. Immunol.
, vol.59
, pp. 1-14
-
-
Kawashima, I.1
Hudson, S.J.2
Tsai, V.3
-
39
-
-
12244282091
-
Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells
-
Miyagi T, Tatsumi T, Takehara T, et al. Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells. J Gastroenterol Hepatol. 2003;18:32-40.
-
(2003)
J. Gastroenterol. Hepatol.
, vol.18
, pp. 32-40
-
-
Miyagi, T.1
Tatsumi, T.2
Takehara, T.3
-
40
-
-
33646165128
-
A central role for central tolerance
-
Kyewski B, Klein L. A central role for central tolerance. Annu Rev Immunol. 2006;24:571-606.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 571-606
-
-
Kyewski, B.1
Klein, L.2
-
41
-
-
15244355148
-
Peripheral tolerance of CD8 T lymphocytes
-
Redmond WL, Sherman LA. Peripheral tolerance of CD8 T lymphocytes. Immunity. 2005;22:275-284.
-
(2005)
Immunity
, vol.22
, pp. 275-284
-
-
Redmond, W.L.1
Sherman, L.A.2
|