Salicylic acid: An old dog, new tricks, and staphylococcal disease

Journal of Clinical Investigation

Volumn 112, Issue 2, 2003, Pages 149-151

  Herrmann, Mathias ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b Inst of Microbiology and Hygiene   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; DRUG METABOLITE; FIBRINOGEN; FIBRONECTIN; HEMOLYSIN; SALICYLIC ACID; VIRULENCE FACTOR; ANTIINFECTIVE AGENT;

BACTERIAL ENDOCARDITIS; BACTERIAL VIRULENCE; DRUG ACTIVITY; DRUG EFFECT; FIBRINOGEN SYNTHESIS; PRIORITY JOURNAL; REVIEW; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; BIOLOGICAL MODEL; HUMAN; MICROBIOLOGY; NOTE; PATHOGENICITY; THROMBOCYTE;

ANTI-BACTERIAL AGENTS; BLOOD PLATELETS; HUMANS; MODELS, BIOLOGICAL; SALICYLIC ACID; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 85047694348     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI19143     Document Type: Review

References (40)

1. Ogston, A. 1882. Micrococcus poisoning. J. Anat. 17:24-58.
2. Cabell, C.H., et al. 2002. Changing patient characteristics and the effect on mortality in endocarditis. Arch. Intern. Med. 162:90-94.
3. Bayer, A.S., and Scheld, W.M. 2000. Endocarditis and intravascular infections. In Principles and practice of infectious diseases. G.L. Mandell, J.E. Bennett, and R. Dolin, editors. Churchill Livingstone. Philadelphia, Pennsylvania, USA. 857-902.
4. 2003. Outbreaks of community-associated methicillin-resistant Staphylococcus aureus skin infections: Los Angeles County, California, 2002-2003. MMWR Morb. Mortal. Wkly. Rep. 52:88.
5. Daum, R.S., et al. 2002. A novel methicillin-resistance cassette in community-acquired methicillin-resistant Staphylococcus aureus isolates of diverse genetic backgrounds. J. Infect. Dis. 186:1344-1347.
6. 2002. Vancomycin-resistant Staphylococcus aureus: Pennsylvania, 2002 [erratum 2002, 51:931]. MMWR Morb. Mortal. Wkly. Rep. 51:902.
7. Lowy, F.D. 1998. Medical progress: Staphylococcus aureus infections. N. Engl. J. Med. 339:520-532.
8. Foster, T.J., and Höök, M. 1998. Surface protein adhesins of Staphylococcus aureus. Trends Microbiol. 6:484-488.
9. Palma, M., Haggar, A., and Flock, J.I. 1999. Adherence of Staphylococcus aureus is enhanced by an endogenous secreted protein with broad binding activity. J. Bacteriol. 181:2840-2845.
10. Hussain, M., et al. 2001. Identification and characterization of a novel 38.8-kilodalton secretory protein of Staphylococcus aureus with extended-spectrum binding activity for extracellular matrix and plasma. J. Bacteriol. 183:6778-6786.
11. Sinha, B., et al. 2000. Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infect. Immun. 68:6871-6878.
12. Que, Y.A., et al. 2001. Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis. Infect. Immun. 69:6296-6302.
13. Cheung, A.L., Nast, C.C., and Bayer, A.S. 1998. Selective activation of sar promoters with the use of green fluorescent protein transcriptional fusions as the detection system in the rabbit endocarditis model. Infect. Immun. 66:5988-5993.
14. Xiong, Y.-Q., et al. 2002. Activation and transcriptional interaction between agr RNAII and RNAIII in Staphylococcus aureus in vitro and in an experimental endocarditis model. J. Infect. Dis. 186:668-677.
15. Durack, D.T. 1975. Experimental bacterial endocarditis. IV. Structure and function of the very early lesions. Br. J. Exp. Pathol. 115:81-80.
16. Clawson, C.C, White, J.G., and Herzberg, M.C. 1980. Platelet interaction with bacteria. VI. Contrasting the role of fibrinogen and fibronectin. Am. J. Hematol. 9:43-53.
17. Herrmann, M., Lai, Q.J., Albrecht, R.M., Mosher, D.F., and Proctor, R.A. 1993. Adhesion of Staphylococcus aureus to surface-bound platelets: role of fibrinogen/fibrin and platelet integrins. J. Infect. Dis. 167:312-322.
18. Siboo, I.R., Cheung, A.L., Bayer, A.S., and Sullam, P.M. 2001. Clumping factor A mediates binding of Staphylococcus aureus to human platelets. Infect. Immun. 69:3120-3127.
19. Sullam, P.M., Bayer, A.S., Foss, W.M., and Cheung, A.L. 1996. Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis. Infect. Immun. 64:4915-4921.
20. Heilmann, C., Herrmann, M., Kehrel, B.E., and Peters, G. 2002. Platelet-binding domains in 2 fibrinogen-binding proteins of Staphylococcus aureus identified by phage display. J. Infect. Dis. 186:32-39.
21. Yeaman, M.R. 1997. The role of platelets in antimicrobial host defense. Clin. Infect. Dis. 25:951-968.
22. Bayer, A.S., et al. 1997. Hyperproduction of alpha-toxin by Staphylococcus aureus results in paradoxically reduced virulence in experimental endocarditis: a host defense role for platelet microbicidal proteins. Infect. Immun. 65:4652-4660.
23. Nicolau, D.P., et al. 1993. Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis. Infect. Immun. 61:1593-1595.
24. Taha, T.H., Durrant, S.S., Mazeika, P.K., Nihoyannopoulos, P., and Oakley, C.M. 1992. Aspirin to prevent growth of vegetations and cerebral emboli in infective endocarditis. J. Intern. Med. 231:543-546.
25. Nicolau, D.P., Tessier, P.R., and Nightingale, C.H. 1999. Beneficial effect of combination antiplatelet therapy on the development of experimental Staphylococcus aureus endocarditis. Int. J. Antimicrob. Agents. 11:159-161.
26. Kupferwasser, L.I., et al. 1999. Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects. Circulation. 99:2791-2797.
27. Kupferwasser, L.I., et al. 2003. Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus. J. Clin. Invest. 112:222-233. doi:10.1172/JCI200316876.
28. Cheung, A.L., et al. 1994. Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis. J. Clin. Invest. 94:1815-1822.
29. Novick, R.P. 2003. Autoinduction and signal transduction in the regulation of staphylococcal virulence. Mol. Microbiol. 48:1429-1449.
30. Proctor, R.A., et al. 2002. Two diarylurea electron transport inhibitors reduce Staphylococcus aureus hemolytic activity and protect cultured endothelial cells from lysis. Antimicrob. Agents Chemother. 46:2333-2336.
31. Kahl, B., et al. 1998. Persistent infection with small colony variant strains of Staphylococcus aureus in patients with cystic fibrosis. J. Infect. Dis. 177:1023-1029.
32. Yarwood, J.M., McCormick, J.K., Paustian, M.L., Kapur, V., and Schlievert, P.M. 2002. Repression of the Staphylococcus aureus accessory gene regulator in serum and in vivo. J. Bacteriol. 184:1095-1101.
33. Wolz, C., Goerke, C., Landmann, R., Zimmerli, W., and Fluckiger, U. 2002. Transcription of clumping factor A in attached and unattached Staphylococcus aureus in vitro and during device-related infection. Infect. Immun. 70:2758-2762.
34. Teichberg, S., Farber, B.F., Wolff, A.G., and Roberts, B. 1993. Salicylic acid decreases extracellular biofilm production by Staphylococcus epidermidis: electron microscopic analysis. J. Infect. Dis. 167:1501-1503.
35. Muller, E., Al Attar, J., Wolff, A.G., and Farber, B.F. 1998. Mechanism of salicylate-mediated inhibition of biofilm in Staphylococcus epidermidis. J. Infect. Dis. 177:501-503.
36. McKenney, D., et al. 1999. Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen. Science. 284:1523-1527.
37. Heilmann, C., et al. 1996. Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol. Microbiol. 20:1083-1091.
38. B in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock. Arch. Microbiol. 167:151-159.
39. Chavakis, T., et al. 2002. Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes. Nat. Med. 8:687-693.
40. Lee, L.Y., et al. 2002. The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell-mediated responses. J. Clin. Invest. 110:1461-1471. doi:10.1172/JCI200216318.