메뉴 건너뛰기




Volumn 22, Issue 8, 2013, Pages 1325-1336

Endothelial progenitor cell-based therapy for pulmonary arterial hypertension

Author keywords

Endothelial progenitor cells (EPCs); Mechanisms; Pulmonary arterial hypertension (PAH); Transplantation

Indexed keywords

ADRENOMEDULLIN; CD133 ANTIGEN; CD34 ANTIGEN; CILOSTAZOL; FIBRONECTIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; PLACENTAL GROWTH FACTOR; SCATTER FACTOR; SILDENAFIL; STROMAL CELL DERIVED FACTOR 1ALPHA; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN RECEPTOR 2;

EID: 85047687247     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368912X659899     Document Type: Review
Times cited : (18)

References (98)
  • 1
    • 27744464592 scopus 로고    scopus 로고
    • Endothelial-mesenchymal transition occurs during embryonic pulmonary artery development
    • Arciniegas, E.; Neves, C. Y.; Carrillo, L. M.; Zambrano, E. A.; Ramirez, R. Endothelial-mesenchymal transition occurs during embryonic pulmonary artery development. Endothelium 12(4):193-200; 2005.
    • (2005) Endothelium , vol.12 , Issue.4 , pp. 193-200
    • Arciniegas, E.1    Neves, C.Y.2    Carrillo, L.M.3    Zambrano, E.A.4    Ramirez, R.5
  • 3
    • 0033565540 scopus 로고    scopus 로고
    • VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells
    • Asahara, T.; Takahashi, T.; Masuda, H.; Kalka, C.; Chen, D.; Iwaguro, H.; Inai, Y.; Silver, M.; Isner, J. M. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J. 18(14):3964-3972; 1999.
    • (1999) EMBO J , vol.18 , Issue.14 , pp. 3964-3972
    • Asahara, T.1    Takahashi, T.2    Masuda, H.3    Kalka, C.4    Chen, D.5    Iwaguro, H.6    Inai, Y.7    Silver, M.8    Isner, J.M.9
  • 5
    • 34047146858 scopus 로고    scopus 로고
    • Is it possible to reverse the endothelial dysfunction in pulmonary arterial hypertension
    • Barst, R. Is it possible to reverse the endothelial dysfunction in pulmonary arterial hypertension? J. Am. Coll. Cardiol. 49(14):1572-1574; 2007.
    • (2007) J. Am. Coll. Cardiol , vol.49 , Issue.14 , pp. 1572-1574
    • Barst, R.1
  • 6
    • 1642453778 scopus 로고    scopus 로고
    • Endothelial dysfunction in pulmonary hypertension
    • Budhiraja, R.; Tuder, R. M.; Hassoun, P. M. Endothelial dysfunction in pulmonary hypertension. Circulation 109(2): 159-165; 2004.
    • (2004) Circulation , vol.109 , Issue.2 , pp. 159-165
    • Budhiraja, R.1    Tuder, R.M.2    Hassoun, P.M.3
  • 7
    • 0035975944 scopus 로고    scopus 로고
    • Cellbased gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension
    • Campbell, A. I.; Zhao, Y.; Sandhu, R.; Stewart, D. J. Cellbased gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension. Circulation 104(18):2242-2248; 2001.
    • (2001) Circulation , vol.104 , Issue.18 , pp. 2242-2248
    • Campbell, A.I.1    Zhao, Y.2    Sandhu, R.3    Stewart, D.J.4
  • 9
    • 37549068962 scopus 로고    scopus 로고
    • Pathogenic mechanisms of pulmonary arterial hypertension
    • Chan, S. Y.; Loscalzo, J. Pathogenic mechanisms of pulmonary arterial hypertension. J. Mol. Cell. Cardiol. 44(1): 14-30; 2008.
    • (2008) J. Mol. Cell. Cardiol , vol.44 , Issue.1 , pp. 14-30
    • Chan, S.Y.1    Loscalzo, J.2
  • 10
    • 37549026759 scopus 로고    scopus 로고
    • Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart
    • Cho, H. J.; Lee, N.; Lee, J. Y.; Choi, Y. J.; Ii, M.; Wecker, A.; Jeong, J. O.; Curry, C.; Qin, G.; Yoon, Y. S. Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart. J. Exp. Med. 204(13):3257-3269; 2007.
    • (2007) J. Exp. Med , vol.204 , Issue.13 , pp. 3257-3269
    • Cho, H.J.1    Lee, N.2    Lee, J.Y.3    Choi, Y.J.4    Ii, M.5    Wecker, A.6    Jeong, J.O.7    Curry, C.8    Qin, G.9    Yoon, Y.S.10
  • 11
    • 0033989282 scopus 로고    scopus 로고
    • Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease
    • Cowan, K. N.; Jones, P. L.; Rabinovitch, M. Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease. J. Clin. Invest. 105(1):21-34; 2000.
    • (2000) J. Clin. Invest , vol.105 , Issue.1 , pp. 21-34
    • Cowan, K.N.1    Jones, P.L.2    Rabinovitch, M.3
  • 13
  • 14
    • 78549254182 scopus 로고    scopus 로고
    • Endothelial progenitor cells in pulmonary arterial hypertension
    • Diller, G. P.; Thum, T.; Wilkins, M. R.; Wharton, J. Endothelial progenitor cells in pulmonary arterial hypertension. Trends Cardiovasc. Med. 20(1):22-29; 2010.
    • (2010) Trends Cardiovasc. Med , vol.20 , Issue.1 , pp. 22-29
    • Diller, G.P.1    Thum, T.2    Wilkins, M.R.3    Wharton, J.4
  • 16
    • 34250613058 scopus 로고    scopus 로고
    • The role of endothelial progenitor cells in ischemic cerebral and heart diseases
    • Ding, D. C.; Shyu, W. C.; Lin, S. Z.; Li, H. The role of endothelial progenitor cells in ischemic cerebral and heart diseases. Cell Transplant. 16(3):273-284; 2007.
    • (2007) Cell Transplant , vol.16 , Issue.3 , pp. 273-284
    • Ding, D.C.1    Shyu, W.C.2    Lin, S.Z.3    Li, H.4
  • 17
    • 66249097415 scopus 로고    scopus 로고
    • Novel cell-free strategy for therapeutic angiogenesis: In vitro generated conditioned medium can replace progenitor cell transplantation
    • Di Santo, S.; Yang, Z.; Wyler von Ballmoos, M.; Voelzmann, J.; Diehm, N.; Baumgartner, I.; Kalka, C. Novel cell-free strategy for therapeutic angiogenesis: In vitro generated conditioned medium can replace progenitor cell transplantation. PLoS One 4(5):e5643; 2009.
    • (2009) PLoS One , vol.4 , Issue.5
    • Di Santo, S.1    Yang, Z.2    Wyler von Ballmoos, M.3    Voelzmann, J.4    Diehm, N.5    Baumgartner, I.6    Kalka, C.7
  • 18
    • 34848869955 scopus 로고    scopus 로고
    • Depletion of endothelial progenitor cells may link pulmonary fibrosis and pulmonary hypertension
    • Fadini, G. P.; Schiavon, M.; Rea, F.; Avogaro, A.; Agostini, C. Depletion of endothelial progenitor cells may link pulmonary fibrosis and pulmonary hypertension. Am. J. Respir. Crit. Care Med. 176(7):724-725; 2007.
    • (2007) Am. J. Respir. Crit. Care Med , vol.176 , Issue.7 , pp. 724-725
    • Fadini, G.P.1    Schiavon, M.2    Rea, F.3    Avogaro, A.4    Agostini, C.5
  • 20
    • 0242469176 scopus 로고    scopus 로고
    • Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells
    • Fujiyama, S.; Amano, K.; Uehira, K.; Yoshida, M.; Nishiwaki, Y.; Nozawa, Y.; Jin, D.; Takai, S.; Miyazaki, M.; Egashira, K.; Imada, T.; Iwasaka, T.; Matsubara, H. Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells. Circ. Res. 93(10):980-989; 2003.
    • (2003) Circ. Res , vol.93 , Issue.10 , pp. 980-989
    • Fujiyama, S.1    Amano, K.2    Uehira, K.3    Yoshida, M.4    Nishiwaki, Y.5    Nozawa, Y.6    Jin, D.7    Takai, S.8    Miyazaki, M.9    Egashira, K.10    Imada, T.11    Iwasaka, T.12    Matsubara, H.13
  • 21
    • 0037899249 scopus 로고    scopus 로고
    • The myofibroblast in wound healing and fibrocontractive diseases
    • Gabbiani, G. The myofibroblast in wound healing and fibrocontractive diseases. J. Pathol. 200(4):500-503; 2003.
    • (2003) J. Pathol , vol.200 , Issue.4 , pp. 500-503
    • Gabbiani, G.1
  • 23
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi, M.; Zhang, Z.; Ni, A.; Dzau, V. J. Paracrine mechanisms in adult stem cell signaling and therapy. Circ. Res. 103(11):1204-1219; 2008.
    • (2008) Circ. Res , vol.103 , Issue.11 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3    Dzau, V.J.4
  • 24
    • 0345306119 scopus 로고    scopus 로고
    • Diverse origin and function of cells with endothelial phenotype obtained from adult human blood
    • Gulati, R.; Jevremovic, D.; Peterson, T. E.; Chatterjee, S.; Shah, V.; Vile, R. G.; Simari, R. D. Diverse origin and function of cells with endothelial phenotype obtained from adult human blood. Circ. Res. 93(11):1023-1025; 2003.
    • (2003) Circ. Res , vol.93 , Issue.11 , pp. 1023-1025
    • Gulati, R.1    Jevremovic, D.2    Peterson, T.E.3    Chatterjee, S.4    Shah, V.5    Vile, R.G.6    Simari, R.D.7
  • 27
    • 19844374754 scopus 로고    scopus 로고
    • Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxiainduced pulmonary hypertension
    • Hayashida, K.; Fujita, J.; Miyake, Y.; Kawada, H.; Ando, K.; Ogawa, S.; Fukuda, K. Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxiainduced pulmonary hypertension. Chest 127(5):1793- 1798; 2005.
    • (2005) Chest , vol.127 , Issue.5 , pp. 1793-1798
    • Hayashida, K.1    Fujita, J.2    Miyake, Y.3    Kawada, H.4    Ando, K.5    Ogawa, S.6    Fukuda, K.7
  • 29
    • 16644369282 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Characterization, pathophysiology, and possible clinical relevance
    • Hristov, M.; Weber, C. Endothelial progenitor cells: Characterization, pathophysiology, and possible clinical relevance. J. Cell. Mol. Med. 8(4):498-508; 2004.
    • (2004) J. Cell. Mol. Med , vol.8 , Issue.4 , pp. 498-508
    • Hristov, M.1    Weber, C.2
  • 30
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert, M.; Sitbon, O.; Simonneau, G. Treatment of pulmonary arterial hypertension. N. Engl. J. Med. 351(14):1425-1436; 2004.
    • (2004) N. Engl. J. Med , vol.351 , Issue.14 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 31
  • 33
    • 44649145119 scopus 로고    scopus 로고
    • Reduced number and activity of circulating endothelial progenitor cells in patients with idiopathic pulmonary arterial hypertension
    • Junhui, Z.; Xingxiang, W.; Guosheng, F.; Yunpeng, S.; Furong, Z.; Junzhu, C. Reduced number and activity of circulating endothelial progenitor cells in patients with idiopathic pulmonary arterial hypertension. Respir. Med. 102(7):1073-1079; 2008.
    • (2008) Respir. Med , vol.102 , Issue.7 , pp. 1073-1079
    • Junhui, Z.1    Xingxiang, W.2    Guosheng, F.3    Yunpeng, S.4    Furong, Z.5    Junzhu, C.6
  • 34
    • 77649337086 scopus 로고    scopus 로고
    • Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials
    • Jurasz, P.; Courtman, D.; Babaie, S.; Stewart, D. J. Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials, Pharmacol. Ther. 126(1):1-8; 2010.
    • (2010) Pharmacol. Ther , vol.126 , Issue.1 , pp. 1-8
    • Jurasz, P.1    Courtman, D.2    Babaie, S.3    Stewart, D.J.4
  • 35
    • 79956006255 scopus 로고    scopus 로고
    • Functional endothelial progenitor cells from cryopreserved umbilical cord blood
    • Lin, R. Z.; Dreyzin, A.; Aamodt, K.; Dudley, A. C.; Melero Martin, J. M. Functional endothelial progenitor cells from cryopreserved umbilical cord blood. Cell Transplant. 20(4): 515-522; 2011.
    • (2011) Cell Transplant , vol.20 , Issue.4 , pp. 515-522
    • Lin, R.Z.1    Dreyzin, A.2    Aamodt, K.3    Dudley, A.C.4    Melero Martin, J.M.5
  • 36
    • 0033989026 scopus 로고    scopus 로고
    • Origins of circulating endothelial cells and endothelial outgrowth from blood
    • Lin, Y.; Weisdorf, D. J.; Solovey, A.; Hebbel, R. P. Origins of circulating endothelial cells and endothelial outgrowth from blood. J. Clin. Invest. 105(1):71-77; 2000.
    • (2000) J. Clin. Invest , vol.105 , Issue.1 , pp. 71-77
    • Lin, Y.1    Weisdorf, D.J.2    Solovey, A.3    Hebbel, R.P.4
  • 37
    • 66849141018 scopus 로고    scopus 로고
    • Assessments of proliferation capacity and viability of New Zealand rabbit peripheral blood endothelial progenitor cells labeled with superparamagnetic particles
    • Mai, X. L.; Ma, Z. L.; Sun, J. H.; Ju, S. H.; Ma, M.; Teng, G. J. Assessments of proliferation capacity and viability of New Zealand rabbit peripheral blood endothelial progenitor cells labeled with superparamagnetic particles. Cell Transplant. 18(2):171-181; 2009.
    • (2009) Cell Transplant , vol.18 , Issue.2 , pp. 171-181
    • Mai, X.L.1    Ma, Z.L.2    Sun, J.H.3    Ju, S.H.4    Ma, M.5    Teng, G.J.6
  • 38
    • 47149090755 scopus 로고    scopus 로고
    • Endothelial progenitor cells: New perspectives and applications in cardiovascular therapies
    • Marsboom, G.; Janssens, S. Endothelial progenitor cells: New perspectives and applications in cardiovascular therapies. Expert. Rev. Cardiovasc. Ther. 6(5):687-701; 2008.
    • (2008) Expert. Rev. Cardiovasc. Ther , vol.6 , Issue.5 , pp. 687-701
    • Marsboom, G.1    Janssens, S.2
  • 41
    • 20444483234 scopus 로고    scopus 로고
    • Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
    • McMurtry, M. S.; Archer, S. L.; Altieri, D. C.; Bonnet, S.; Haromy, A.; Harry, G.; Puttagunta, L.; Michelakis, E. D. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J. Clin. Invest. 115(6):1479-1491; 2005.
    • (2005) J. Clin. Invest , vol.115 , Issue.6 , pp. 1479-1491
    • McMurtry, M.S.1    Archer, S.L.2    Altieri, D.C.3    Bonnet, S.4    Haromy, A.5    Harry, G.6    Puttagunta, L.7    Michelakis, E.D.8
  • 42
    • 77952065242 scopus 로고    scopus 로고
    • Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities
    • Medina, R. J.; O'Neill, C. L.; Sweeney, M.; Guduric-Fuchs, J.; Gardiner, T. A.; Simpson, D. A.; Stitt, A. W. Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities. BMC Med. Genomics 3:18; 2010.
    • (2010) BMC Med. Genomics , vol.3 , pp. 18
    • Medina, R.J.1    O'Neill, C.L.2    Sweeney, M.3    Guduric-Fuchs, J.4    Gardiner, T.A.5    Simpson, D.A.6    Stitt, A.W.7
  • 43
    • 0018333675 scopus 로고
    • Hypoxia and incorporation of 3Hthymidine by cells of the rat pulmonary arteries and alveolar wall
    • Meyrick, B.; Reid, L. Hypoxia and incorporation of 3Hthymidine by cells of the rat pulmonary arteries and alveolar wall. Am. J. Pathol. 96(1):51-70; 1979.
    • (1979) Am. J. Pathol , vol.96 , Issue.1 , pp. 51-70
    • Meyrick, B.1    Reid, L.2
  • 44
    • 0020003049 scopus 로고
    • Crotalaria-induced pulmonary hypertension. Uptake of 3H-thymidine by the cells of the pulmonary circulation and alveolar walls
    • Meyrick, B. O.; Reid, L. M. Crotalaria-induced pulmonary hypertension. Uptake of 3H-thymidine by the cells of the pulmonary circulation and alveolar walls. Am. J. Pathol. 106(1):84-94; 1982.
    • (1982) Am. J. Pathol , vol.106 , Issue.1 , pp. 84-94
    • Meyrick, B.O.1    Reid, L.M.2
  • 45
    • 34547866709 scopus 로고    scopus 로고
    • Endothelial progenitor cells as a new agent contributing to vascular repair
    • Miller-Kasprzak, E.; Jagodzinski, P. P. Endothelial progenitor cells as a new agent contributing to vascular repair. Arch. Immunol. Ther. Exp. 55(4):247-259; 2007.
    • (2007) Arch. Immunol. Ther. Exp , vol.55 , Issue.4 , pp. 247-259
    • Miller-Kasprzak, E.1    Jagodzinski, P.P.2
  • 49
    • 78049388103 scopus 로고    scopus 로고
    • Innate immunity in the therapeutic actions of endothelial progenitor cells in pulmonary hypertension
    • Ormiston, M. L.; Deng, Y.; Stewart, D. J.; Courtman, D. W. Innate immunity in the therapeutic actions of endothelial progenitor cells in pulmonary hypertension. Am. J. Respir. Cell Mol. Biol. 43(5):546-554; 2010.
    • (2010) Am. J. Respir. Cell Mol. Biol , vol.43 , Issue.5 , pp. 546-554
    • Ormiston, M.L.1    Deng, Y.2    Stewart, D.J.3    Courtman, D.W.4
  • 50
    • 67449104055 scopus 로고    scopus 로고
    • Cardiac stem cell therapy: Advances from 2008
    • Patel, A. N.; Sherman, W. Cardiac stem cell therapy: Advances from 2008. Cell Transplant. 18(3):243-244; 2009.
    • (2009) Cell Transplant , vol.18 , Issue.3 , pp. 243-244
    • Patel, A.N.1    Sherman, W.2
  • 51
    • 12944253116 scopus 로고    scopus 로고
    • Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors
    • Peichev, M.; Naiyer, A. J.; Pereira, D.; Zhu, Z.; Lane, W. J.; Williams, M.; Oz, M. C.; Hicklin, D. J.; Witte, L.; Moore, M. A.; Rafii, S. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 95(3):952-958; 2000.
    • (2000) Blood , vol.95 , Issue.3 , pp. 952-958
    • Peichev, M.1    Naiyer, A.J.2    Pereira, D.3    Zhu, Z.4    Lane, W.J.5    Williams, M.6    Oz, M.C.7    Hicklin, D.J.8    Witte, L.9    Moore, M.A.10    Rafii, S.11
  • 52
    • 34249704141 scopus 로고    scopus 로고
    • Working hypothesis to redefine endothelial progenitor cells
    • Prater, D. N.; Case, J.; Ingram, D. A.; Yoder, M. C. Working hypothesis to redefine endothelial progenitor cells. Leukemia 21(6):1141-1149; 2007.
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1141-1149
    • Prater, D.N.1    Case, J.2    Ingram, D.A.3    Yoder, M.C.4
  • 54
    • 74949094846 scopus 로고    scopus 로고
    • Feeling the elephant of cardiovascular cell therapy
    • Rehman, J. Feeling the elephant of cardiovascular cell therapy. Circulation 121(2):197-199; 2010.
    • (2010) Circulation , vol.121 , Issue.2 , pp. 197-199
    • Rehman, J.1
  • 55
    • 0037418213 scopus 로고    scopus 로고
    • Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors
    • Rehman, J.; Li, J.; Orschell, C. M.; March, K. L. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 107(8):1164-1169; 2003.
    • (2003) Circulation , vol.107 , Issue.8 , pp. 1164-1169
    • Rehman, J.1    Li, J.2    Orschell, C.M.3    March, K.L.4
  • 57
    • 78649872095 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Quo vadis
    • Richardson, M. R.; Yoder, M. C. Endothelial progenitor cells: Quo vadis? J. Mol. Cell. Cardiol. 50(2):266-272; 2011.
    • (2011) J. Mol. Cell. Cardiol , vol.50 , Issue.2 , pp. 266-272
    • Richardson, M.R.1    Yoder, M.C.2
  • 59
    • 43449134371 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension in children: A medical update
    • Rosenzweig, E. B.; Barst, R. J. Pulmonary arterial hypertension in children: A medical update. Curr. Opin. Pediatr. 20(3):288-293; 2008.
    • (2008) Curr. Opin. Pediatr , vol.20 , Issue.3 , pp. 288-293
    • Rosenzweig, E.B.1    Barst, R.J.2
  • 61
    • 0037623284 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Runo, J. R.; Loyd, J. E. Primary pulmonary hypertension. Lancet 361(9368):1533-1544; 2003.
    • (2003) Lancet , vol.361 , Issue.9368 , pp. 1533-1544
    • Runo, J.R.1    Loyd, J.E.2
  • 63
    • 34248326063 scopus 로고    scopus 로고
    • Endothelial progenitor cells stimulate cerebrovascular production of prostacyclin by paracrine activation of cyclooxygenase-2
    • Santhanam, A. V.; Smith, L. A.; He, T.; Nath, K. A.; Katusic, Z. S. Endothelial progenitor cells stimulate cerebrovascular production of prostacyclin by paracrine activation of cyclooxygenase-2. Circ. Res. 100(9):1379- 1388; 2007.
    • (2007) Circ. Res , vol.100 , Issue.9 , pp. 1379-1388
    • Santhanam, A.V.1    Smith, L.A.2    He, T.3    Nath, K.A.4    Katusic, Z.S.5
  • 64
    • 20444458775 scopus 로고    scopus 로고
    • Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: Proof of concept for the clinical importance of endogenous vascular repair
    • Schmidt-Lucke, C.; Rossig, L.; Fichtlscherer, S.; Vasa, M.; Britten, M.; Kamper, U.; Dimmeler, S.; Zeiher, A. M. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: Proof of concept for the clinical importance of endogenous vascular repair. Circulation 111(22):2981-2987; 2005.
    • (2005) Circulation , vol.111 , Issue.22 , pp. 2981-2987
    • Schmidt-Lucke, C.1    Rossig, L.2    Fichtlscherer, S.3    Vasa, M.4    Britten, M.5    Kamper, U.6    Dimmeler, S.7    Zeiher, A.M.8
  • 65
    • 38749090588 scopus 로고    scopus 로고
    • Strikingly different angiogenic properties of endothelial progenitor cell subpopulations: Insights from a novel human angiogenesis assay
    • Sieveking, D. P.; Buckle, A.; Celermajer, D. S.; Ng, M. K. Strikingly different angiogenic properties of endothelial progenitor cell subpopulations: Insights from a novel human angiogenesis assay. J. Am. Coll. Cardiol. 51(6): 660-668; 2008.
    • (2008) J. Am. Coll. Cardiol , vol.51 , Issue.6 , pp. 660-668
    • Sieveking, D.P.1    Buckle, A.2    Celermajer, D.S.3    Ng, M.K.4
  • 69
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
    • Stenmark, K. R.; Fagan, K. A.; Frid, M. G. Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms. Circ. Res. 99(7):675-691; 2006.
    • (2006) Circ. Res , vol.99 , Issue.7 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 70
    • 70349092330 scopus 로고    scopus 로고
    • Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats
    • Sun, C. K.; Lee, F. Y.; Sheu, J. J.; Yuen, C. M.; Chua, S.; Chung, S. Y.; Chai, H. T.; Chen, Y. T.; Kao, Y. H.; Chang, L. T.; Yip, H. K. Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats. J. Pharmacol. Exp. Ther. 330(3):718-726; 2009.
    • (2009) J. Pharmacol. Exp. Ther , vol.330 , Issue.3 , pp. 718-726
    • Sun, C.K.1    Lee, F.Y.2    Sheu, J.J.3    Yuen, C.M.4    Chua, S.5    Chung, S.Y.6    Chai, H.T.7    Chen, Y.T.8    Kao, Y.H.9    Chang, L.T.10    Yip, H.K.11
  • 71
    • 84870242807 scopus 로고    scopus 로고
    • Enhanced protection against pulmonary hypertension with sildenafil and endothelial progenitor cell in rats
    • Sun, C. K.; Lin, Y. C.; Yuen, C. M.; Chua, S.; Chang, L. T.; Sheu, J. J.; Lee, F. Y.; Fu, M.; Leu, S.; Yip, H. K. Enhanced protection against pulmonary hypertension with sildenafil and endothelial progenitor cell in rats. Int. J. Cardiol. 162:45-58; 2012.
    • (2012) Int. J. Cardiol , vol.162 , pp. 45-58
    • Sun, C.K.1    Lin, Y.C.2    Yuen, C.M.3    Chua, S.4    Chang, L.T.5    Sheu, J.J.6    Lee, F.Y.7    Fu, M.8    Leu, S.9    Yip, H.K.10
  • 72
    • 3042732877 scopus 로고    scopus 로고
    • Transplantation of endothelial progenitor cells into the lung to alleviate pulmonary hypertension in dogs
    • Takahashi, M.; Nakamura, T.; Toba, T.; Kajiwara, N.; Kato, H.; Shimizu, Y. Transplantation of endothelial progenitor cells into the lung to alleviate pulmonary hypertension in dogs. Tissue Eng. 10(5-6):771-779; 2004.
    • (2004) Tissue Eng , vol.10 , Issue.5-6 , pp. 771-779
    • Takahashi, M.1    Nakamura, T.2    Toba, T.3    Kajiwara, N.4    Kato, H.5    Shimizu, Y.6
  • 73
    • 33644865928 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: Implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
    • Teichert-Kuliszewska, K.; Kutryk, M. J.; Kuliszewski, M. A.; Karoubi, G.; Courtman, D. W.; Zucco, L.; Granton, J.; Stewart, D. J. Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: Implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ. Res. 98(2):209-217; 2006.
    • (2006) Circ. Res , vol.98 , Issue.2 , pp. 209-217
    • Teichert-Kuliszewska, K.1    Kutryk, M.J.2    Kuliszewski, M.A.3    Karoubi, G.4    Courtman, D.W.5    Zucco, L.6    Granton, J.7    Stewart, D.J.8
  • 76
    • 33745544013 scopus 로고    scopus 로고
    • Contraction of myofibroblasts in granulation tissue is dependent on Rho/ Rho kinase/myosin light chain phosphatase activity
    • Tomasek, J. J.; Vaughan, M. B.; Kropp, B. P.; Gabbiani, G.; Martin, M. D.; Haaksma, C. J.; Hinz, B. Contraction of myofibroblasts in granulation tissue is dependent on Rho/ Rho kinase/myosin light chain phosphatase activity. Wound Repair Regen. 14(3):313-320; 2006.
    • (2006) Wound Repair Regen , vol.14 , Issue.3 , pp. 313-320
    • Tomasek, J.J.1    Vaughan, M.B.2    Kropp, B.P.3    Gabbiani, G.4    Martin, M.D.5    Haaksma, C.J.6    Hinz, B.7
  • 81
    • 0034904703 scopus 로고    scopus 로고
    • Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene
    • Tuder, R. M.; Yeager, M. E.; Geraci, M.; Golpon, H. A.; Voelkel, N. F. Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene. Eur. Respir. J. 17(6):1065-1069; 2001.
    • (2001) Eur. Respir. J , vol.17 , Issue.6 , pp. 1065-1069
    • Tuder, R.M.1    Yeager, M.E.2    Geraci, M.3    Golpon, H.A.4    Voelkel, N.F.5
  • 82
    • 26844525184 scopus 로고    scopus 로고
    • Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells
    • Urbich, C.; Aicher, A.; Heeschen, C.; Dernbach, E.; Hofmann, W. K.; Zeiher, A. M.; Dimmeler, S. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J. Mol. Cell. Cardiol. 39(5):733-742; 2005.
    • (2005) J. Mol. Cell. Cardiol , vol.39 , Issue.5 , pp. 733-742
    • Urbich, C.1    Aicher, A.2    Heeschen, C.3    Dernbach, E.4    Hofmann, W.K.5    Zeiher, A.M.6    Dimmeler, S.7
  • 83
    • 4143052506 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Characterization and role in vascular biology
    • Urbich, C.; Dimmeler, S. Endothelial progenitor cells: Characterization and role in vascular biology. Circ. Res. 95(4):343-353; 2004.
    • (2004) Circ. Res , vol.95 , Issue.4 , pp. 343-353
    • Urbich, C.1    Dimmeler, S.2
  • 86
    • 0036245561 scopus 로고    scopus 로고
    • Janus face of vascular endothelial growth factor: The obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension
    • Voelkel, N. F.; Cool, C.; Taraceviene-Stewart, L.; Geraci, M. W.; Yeager, M.; Bull, T.; Kasper, M.; Tuder, R. M. Janus face of vascular endothelial growth factor: The obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Crit. Care Med. 30(5 Suppl):S251-S256; 2002.
    • (2002) Crit. Care Med , vol.30 , Issue.SUPPL. 5
    • Voelkel, N.F.1    Cool, C.2    Taraceviene-Stewart, L.3    Geraci, M.W.4    Yeager, M.5    Bull, T.6    Kasper, M.7    Tuder, R.M.8
  • 87
    • 34047108549 scopus 로고    scopus 로고
    • Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: A pilot randomized controlled trial
    • Wang, X. X.; Zhang, F. R.; Shang, Y. P.; Zhu, J. H.; Xie, X. D.; Tao, Q. M.; Chen, J. Z. Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: A pilot randomized controlled trial. J. Am. Coll. Cardiol. 49(14):1566-1571; 2007.
    • (2007) J. Am. Coll. Cardiol , vol.49 , Issue.14 , pp. 1566-1571
    • Wang, X.X.1    Zhang, F.R.2    Shang, Y.P.3    Zhu, J.H.4    Xie, X.D.5    Tao, Q.M.6    Chen, J.Z.7
  • 88
    • 0041733082 scopus 로고    scopus 로고
    • Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury
    • Werner, N.; Junk, S.; Laufs, U.; Link, A.; Walenta, K.; Bohm, M.; Nickenig, G. Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ. Res. 93(2):e17-e24; 2003.
    • (2003) Circ. Res , vol.93 , Issue.2
    • Werner, N.1    Junk, S.2    Laufs, U.3    Link, A.4    Walenta, K.5    Bohm, M.6    Nickenig, G.7
  • 90
    • 0034662287 scopus 로고    scopus 로고
    • DNA damage cell checkpoint activities are altered in monocrotaline pyrrole-induced cell cycle arrest in human pulmonary artery endothelial cells
    • Wilson, D. W.; Lame, M. W.; Dunston, S. K.; Segall, H. J. DNA damage cell checkpoint activities are altered in monocrotaline pyrrole-induced cell cycle arrest in human pulmonary artery endothelial cells. Toxicol. Appl. Pharmacol. 166(2):69-80; 2000.
    • (2000) Toxicol. Appl. Pharmacol , vol.166 , Issue.2 , pp. 69-80
    • Wilson, D.W.1    Lame, M.W.2    Dunston, S.K.3    Segall, H.J.4
  • 91
    • 68049148069 scopus 로고    scopus 로고
    • Endothelial progenitor cells may inhibit apoptosis of pulmonary microvascular endothelial cells: New insights into cell therapy for pulmonary arterial hypertension
    • Xia, L.; Fu, G. S.; Yang, J. X.; Zhang, F. R.; Wang, X. X. Endothelial progenitor cells may inhibit apoptosis of pulmonary microvascular endothelial cells: New insights into cell therapy for pulmonary arterial hypertension, Cytotherapy 11(4):492-502; 2009.
    • (2009) Cytotherapy , vol.11 , Issue.4 , pp. 492-502
    • Xia, L.1    Fu, G.S.2    Yang, J.X.3    Zhang, F.R.4    Wang, X.X.5
  • 92
    • 70449519267 scopus 로고    scopus 로고
    • Senescent endothelial progenitor cells from dogs with pulmonary arterial hypertension: A before- after self-controlled study
    • Xia, L.; Zhu, J. H.; Qiu, F. Y.; Yang, Y.; Xie, X. D.; Wang, X. X.; Chen, J. Z.; Fu, G. S. Senescent endothelial progenitor cells from dogs with pulmonary arterial hypertension: A before- after self-controlled study. J. Physiol. Sci. 59(6): 429-437; 2009.
    • (2009) J. Physiol. Sci , vol.59 , Issue.6 , pp. 429-437
    • Xia, L.1    Zhu, J.H.2    Qiu, F.Y.3    Yang, Y.4    Xie, X.D.5    Wang, X.X.6    Chen, J.Z.7    Fu, G.S.8
  • 93
    • 77749273896 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide nanoparticles may affect endothelial progenitor cell migration ability and adhesion capacity
    • Yang, J. X.; Tang, W. L.; Wang, X. X. Superparamagnetic iron oxide nanoparticles may affect endothelial progenitor cell migration ability and adhesion capacity. Cytotherapy 12(2):251-259; 2010.
    • (2010) Cytotherapy , vol.12 , Issue.2 , pp. 251-259
    • Yang, J.X.1    Tang, W.L.2    Wang, X.X.3
  • 95
    • 44449126784 scopus 로고    scopus 로고
    • Autologous transplantation of bone marrow-derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats
    • Yip, H. K.; Chang, L. T.; Sun, C. K.; Sheu, J. J.; Chiang, C. H.; Youssef, A. A.; Lee, F. Y.; Wu, C. J.; Fu, M. Autologous transplantation of bone marrow-derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats. Crit. Care Med. 36(3):873- 880; 2008.
    • (2008) Crit. Care Med , vol.36 , Issue.3 , pp. 873-880
    • Yip, H.K.1    Chang, L.T.2    Sun, C.K.3    Sheu, J.J.4    Chiang, C.H.5    Youssef, A.A.6    Lee, F.Y.7    Wu, C.J.8    Fu, M.9
  • 96
    • 34447570619 scopus 로고    scopus 로고
    • Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension
    • Zhao, Q.; Liu, Z.; Wang, Z.; Yang, C.; Liu, J.; Lu, J. Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann. Thorac. Surg. 84(2):544-552; 2007.
    • (2007) Ann. Thorac. Surg , vol.84 , Issue.2 , pp. 544-552
    • Zhao, Q.1    Liu, Z.2    Wang, Z.3    Yang, C.4    Liu, J.5    Lu, J.6
  • 97
    • 14844360656 scopus 로고    scopus 로고
    • Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrowderived endothelial-like progenitor cells: Efficacy of combined cell and eNOS gene therapy in established disease
    • Zhao, Y. D.; Courtman, D. W.; Deng, Y.; Kugathasan, L.; Zhang, Q.; Stewart, D. J. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrowderived endothelial-like progenitor cells: Efficacy of combined cell and eNOS gene therapy in established disease. Circ. Res. 96(4):442-450; 2005.
    • (2005) Circ. Res , vol.96 , Issue.4 , pp. 442-450
    • Zhao, Y.D.1    Courtman, D.W.2    Deng, Y.3    Kugathasan, L.4    Zhang, Q.5    Stewart, D.J.6
  • 98
    • 49349116828 scopus 로고    scopus 로고
    • Safety and efficacy of autologous endothelial progenitor cells transplantation in children with idiopathic pulmonary arterial hypertension: Open-label pilot study
    • Zhu, J. H.; Wang, X. X.; Zhang, F. R.; Shang, Y. P.; Tao, Q. M.; Chen, J. Z,Safety and efficacy of autologous endothelial progenitor cells transplantation in children with idiopathic pulmonary arterial hypertension: Open-label pilot study. Pediatr. Transplant. 12(6):650- 655; 2008.
    • (2008) Pediatr. Transplant , vol.12 , Issue.6 , pp. 650-655
    • Zhu, J.H.1    Wang, X.X.2    Zhang, F.R.3    Shang, Y.P.4    Tao, Q.M.5    Chen, J.Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.