TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype

Cell

Volumn 174, Issue 2, 2018, Pages 285-299.e12

  Li, Chaoran ^a   DiSpirito, Joanna R ^a   Zemmour, David ^a   Spallanzani, Raul German ^a   Kuswanto, Wilson ^a   Benoist, Christophe ^a   Mathis, Diane ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

adipose tissue; Foxp3; IL 33; immunometabolism; immunoregulation; PPAR ; regulatory T cell; TCR transgenic mice

Indexed keywords

INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; INTERLEUKIN RECEPTOR; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; IL1RL1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN; INTERLEUKIN-33 RECEPTOR, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RNA; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CELL TRANSFER; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; INTRA-ABDOMINAL FAT; LYMPH NODE; LYMPHOCYTE CULTURE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; SPLEEN; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CHEMISTRY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYTOLOGY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; MACROPHAGE; METABOLISM; SINGLE CELL ANALYSIS;

ANIMALS; CHROMATIN ASSEMBLY AND DISASSEMBLY; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-1 RECEPTOR-LIKE 1 PROTEIN; INTRA-ABDOMINAL FAT; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHENOTYPE; PPAR GAMMA; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN; RNA; SINGLE-CELL ANALYSIS; SPLEEN; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTOME;

EID: 85047364974     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.05.004     Document Type: Article

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