RIM1/2-mediated facilitation of cav1.4 channel opening is required for Ca2+-stimulated release in mouse rod photoreceptors

Journal of Neuroscience

Volumn 35, Issue 38, 2015, Pages 13133-13147

  Grabner, Chad P ^a   Gandini, Maria A ^b   Rehak, Renata ^b   Le, Yun ^c   Zamponi, Gerald W ^b   Schmitz, Frank ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

CaV1.4; Evoked release; Mouse rod photoreceptor; Night blindness; Ribbon synapse; RIM

Indexed keywords

ANTIBODY; BARIUM CHLORIDE; CALCIUM ION; CAV1.4 CALCIUM CHANNEL; CRE RECOMBINASE; GLUTAMATE TRANSPORTER; PROTEIN; RIM 1 PROTEIN; RIM 2 PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; AMINO ACID RECEPTOR AFFECTING AGENT; ASPARTIC ACID; BARIUM DERIVATIVE; BENZYLOXYASPARTATE; CACNA1F PROTEIN, MOUSE; CALCIUM; CALCIUM CHANNEL; CHLORIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; RAB PROTEIN; RIM2 PROTEIN, MOUSE; RIMS1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; CURRENT DENSITY; ELECTRON MICROSCOPY; EVOKED RESPONSE; FACILITATION; FEMALE; GENE INACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE CAPACITANCE MEASUREMENT; MEMBRANE DEPOLARIZATION; MOUSE; NERVOUS SYSTEM PARAMETERS; NIGHT BLINDNESS; NONHUMAN; OCULAR TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA ROD; SYNAPSE; SYNAPTIC TRANSMISSION; WESTERN BLOTTING; WHOLE CELL PATCH CLAMP; ANIMAL; BIOPHYSICS; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; MEMBRANE POTENTIAL; METABOLISM; NERVE ENDING; PHYSIOLOGY; RETINA; SYNAPSE VESICLE; SYNAPTOSOME; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; ASPARTIC ACID; BARIUM COMPOUNDS; BIOPHYSICAL PROCESSES; CALCIUM; CALCIUM CHANNELS; CHLORIDES; EXCITATORY AMINO ACID AGENTS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PRESYNAPTIC TERMINALS; RAB3 GTP-BINDING PROTEINS; RETINA; RETINAL ROD PHOTORECEPTOR CELLS; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES;

EID: 85047289897     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0658-15.2015     Document Type: Article

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