Genomic definition of RIM proteins: Evolutionary amplification of a family of synaptic regulatory proteins

Genomics

Volumn 81, Issue 2, 2003, Pages 126-137

  Wang, Yun ^a   Südhof, Thomas C ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Alternative promoters; Alternative splicing; C2 domains; ERCs; Gene duplication; Liprins; Munc13; Neurotransmitter release; Rab3; Synapse; Zn2+ finger

Indexed keywords

ADAPTOR PROTEIN; PROTEIN RIM; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE DUPLICATION; GENE FUNCTION; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSCRIPTION; GENOMICS; HUMAN; INVERTEBRATE; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; VERTEBRATE; ZINC FINGER MOTIF;

INVERTEBRATA; VERTEBRATA;

EID: 0037295116     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0888-7543(02)00024-1     Document Type: Article

References (25)

1. Lonart G. RIM1 an edge for presynaptic plasticity . Trends Neurosci. 25:2002;329-332.
2. Dresbach T., Qualmann B., Kessels M.M., Garner C.C., Gundelfinger E.D. The presynaptic cytomatrix of brain synapses. Cell. Mol. Life Sci. 58:2001;94-116.
3. Wang Y., Okamoto M., Schmitz F., Hofman K., Südhof T.C. RIM a putative Rab3-effector in regulating synaptic vesicle fusion . Nature. 388:1997;593-598.
4. Wang Y., Sugita S., Südhof T.C. The RIM/NIM family of neuronal SH3-domain proteins interactions with Rab3 and a new class of neuronal SH3-domain proteins . J. Biol. Chem. 275:2000;20033-20044.
5. Koushika S.P., Richmond J.E., Hadwiger G., Weimer R.M., Jorgensen E.M., Nonet M.L. A post-docking role for active zone protein Rim. Nat. Neurosci. 4:2001;997-1005.
6. Schoch S., Castillo P.E., Jo T., Mukherjee K., Geppert M., Wang Y., Schmitz F., Malenka R.C., Südhof T.C. RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature. 415:2002;321-326.
7. Castillo P.E., Schoch S., Schmitz F., Südhof T.C., Malenka R.C. RIM1α is required for presynaptic long-term potentiation. Nature. 415:2002;327-330.
8. Geppert M., Bolshakov V.Y., Siegelbaum S.A., Takei K., De Camilli P., Hammer R.E., Südhof T.C. The role of Rab3A in neurotransmitter release. Nature. 369:1994;493-497.
9. Geppert M., Goda Y., Stevens C.F., Südhof T.C. Rab3A regulates a late step in synaptic vesicle fusion. Nature. 387:1997;810-814.
10. Castillo P.E., Janz R., Tzounopoulos T., Südhof T.C., Malenka R.C., Nicoll R.A. The synaptic vesicle protein Rab3A is essential for mossy fiber long term potentiation in the hippocampus. Nature. 388:1997;590-593.
11. Betz A., Thakur P., Junge H.J., Ashery U., Rhee J.S., Scheuss V., Rosenmund C., Rettig J., Brose N. Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming. Neuron. 30:2001;183-196.
12. Wang X., Hu B., Zimmermann B., Kilimann M.W. Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal α-helix motifs. J. Biol. Chem. 276:2001;32480-32488.
13. Nakata T., Kitamura Y., Shimizu K., Tanaka S., Fujimori M., Yokoyama S., Ito K., Emi M. Fusion of a novel gene, ELKS, to RET due to translocation t(10;12) (q11;p13) in a papillary thyroid carcinoma. Genes Chromosomes Cancer. 25:1999;97-103.
14. Monier S., Jollivet F., Janoueix-Lerosey I., Johannes L., Goud B. Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport. Traffic. 3:2002;289-297.
15. Ohtsuka T., Takao-Rikitsu E., Inoue E., Inoue M., Takeuchi M., Matsubara K., Deguchi-Tawarada M., Satoh K., Morimoto K., Nakanishi H., Takai Y. Cast a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1 . J. Cell Biol. 158:2000;577-590.
16. Wang Y., Liu X., Biederer T., Südhof T.C. A family of RIM-binding proteins regulated by alternative splicing implications for the genesis of synaptic active zones . Proc. Natl. Acad. Sci. USA. 99:2002;14464-14469.
17. Zhen M., Jin Y. The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans. Nature. 401:1999;371-375.
18. Kaufmann N., DeProto J., Ranjan R., Wan H., Van Vactor D. Drosophila liprin-α and the receptor phosphatase Dlar control synapse morphogenesis. Neuron. 34:2002;27-38.
19. Coppola T., Magnin-Luthi S., Perret-Menoud V., Gattesco S., Schiavo G., Regazzi R. J. Biol. Chem. 276:2001;32756-32762.
20. Koenig M., Monaco A.P., Kunkel L.M. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell. 53:1988;219-226.
21. Tabuchi K., Südhof T.C. Structure and evolution of the neurexin genes insight into the mechanism of alternative splicing . Genomics. 79:2002;849-859.
22. Altschul S.F., et al. Gapped BLAST and PSI-BLAST a new generation of protein database search programs . Nucleic Acids Res. 25:1997;3389-3402.
23. Johnston P.A., Jahn R., Südhof T.C. Transmembrane topography and evolutionary conservation of synaptophysin. J. Biol. Chem. 264:1989;1268-1273.
24. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 277:1970;680-685.
25. Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets procedure and some applications . Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.