Human mitochondrial Mrs2 protein promotes multidrug resistance in gastric cancer cells by regulating p27, cyclin D1 expression and cytochrome C release

Cancer Biology and Therapy

Volumn 8, Issue 7, 2009, Pages 607-614

  Chen, Yu ^a   Wei, Xufeng ^b   Yan, Pengfei ^a   Han, Ying ^a   Sun, Shiren ^a   Wu, Kaichun ^a   Fan, Daiming ^a,b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle; Drug resistance; Gastric cancer; Human mitochondrial Mrs2 protein

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; COMPLEMENTARY DNA; CYCLIN D1; CYTOCHROME C; DOXORUBICIN; FLUOROURACIL; ION CHANNEL; MAGNESIUM ION; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL PROTEIN MRS2; PROTEIN P27; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VINCRISTINE; CATION TRANSPORT PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MRS2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CELL CYCLE; CELL GROWTH; CONTROLLED STUDY; ENZYME RELEASE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GROWTH RATE; HUMAN; HUMAN CELL; ION TRANSPORT; MITOCHONDRIAL MEMBRANE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; TREATMENT OUTCOME; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; DRUG RESISTANCE; GENETICS; METABOLISM; STOMACH TUMOR; TUMOR CELL LINE; UPREGULATION;

ANIMALS; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOCHROMES C; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MITOCHONDRIAL PROTEINS; STOMACH NEOPLASMS; UP-REGULATION;

EID: 85046914517     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.7.7920     Document Type: Article

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