Aged garlic extract inhibits angiogenesis and proliferation of colorectal carcinoma cells

Journal of Nutrition

Volumn 136, Issue 3, 2006, Pages

  Matsuura, Nariaki ^a   Miyamae, Yumiko ^a   Yamane, Kyoko ^a   Nagao, Yukinori ^a   Hamada, Yoshinosuke ^a   Kawaguchi, Naomasa ^a   Katsuki, Takefumi ^b   Hirata, Keiji ^b   Sumi, Shin Ichiro ^c   Ishikawa, Hideki ^d  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^c WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

^d KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Aged garlic extract; Angiogenesis; Chemoprevention; Colon cancer

Indexed keywords

ANTINEOPLASTIC AGENT; COLLAGEN; FIBRONECTIN; GARLIC EXTRACT;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; CANCER CELL; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CHEMOPROPHYLAXIS; COLON CARCINOGENESIS; COLORECTAL CANCER; CONFERENCE PAPER; DRUG INHIBITION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL;

ALLIUM SATIVUM;

EID: 33644833799     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.3.842s     Document Type: Conference Paper

References (25)

1. Dove-Edwin I, Thomas HI. The prevention of colorectal cancer. Aliment Pharmacol Ther. 2001;15:323-36.
2. Tominaga S, Kato I. Diet, nutrition and cancer in Japan. Nutr Health. 1992;8:125-32.
3. Milner JA. 9 Molecular targets for bioactive food components. J Nutr. 2004;134:2492S-8S.
4. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell. 1996;87:159-75.
5. Vogelstein B, Knizler KW. The multistep nature of cancer. Trends Genet. 1993;9:138-41.
6. Bostick RM. Diet and nutrition in the etiology and primary prevention of colon cancer. In: Bendich A, Deckelbaum RJ, editors. Preventive Nutrition. New Jersey: Humana Press; 1997. p.57-95.
7. Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Koprio J, Koskenvuo M, Pukkala E, Skytthe A, Hemminki K. Environmental and heritable factors in the causation of cancer: analysis of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med. 2000;343:78-85.
8. Fleischauer AT, Arab L. Garlic and cancer: a critical review of the epidemiologic literature. J Nutr. 2001;131:1032S-40S.
9. Robert V, Mouille B, Mayeur C, Michaud M, Blachier F. Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: evidence of sensitive and resistant sub-populations. Carcinogenesis. 2001;22:1155-61.
10. Knowles LM, Milner JA. Diallyl disulfide induces ERK phosphorylation and alters gene expression profiles in human colon tumor cells. J Nutr. 2003;133:2901-6.
11. Sengupta A, Ghosh S, Das S. Modulatory in.uence of garlic and tomato on cyclooxygenase-2 activity, cell proliferation and apoptosis during azoxymethane induced colon carcinogenesis in rat. Cancer Lett. 2004;208:127-36.
12. Jiang B, Morimoto S, Yang J, Niinoabu T, Fukuo K, Ogihara T. Expression of parathyroid hormone/parathyroid hormone-related protein receptor in vascular endothelial cells. J Cardiovasc Pharmacol. 1998;31:S142-144.
13. Imai J, Ide N, Nagae S, Moriguchi T, Matsuura H, Itakura Y. Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Med. 1994;60:417-20.
14. Moriguchi T, Saito H, Nishiyama N. Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse. Biol Pharm Bull. 1996;19:305-7.
15. Merchan JR, Chan B, Kale S, Schnipper LE, Sukhatme VP. In vitro and in vivo induction of antiangiogenic activity by plasminogen activators and Captopril. J Natl Cancer Inst. 2003;95:388-99.
16. Albini A, Iwamoto Y, Kleinman HK, Martin GR, Aaronson SA, Kozlowski JM, McEwan RN. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res. 1987;47:3239-45.
17. Ronot X, Doisy A, Tracqui P. Quantitative study of dynamic behavior of cell monolayers during in vitro wound healing by optical flow analysis. Cytometry. 2000;41:19-30.
18. Funahashi Y, Sugi NH, Semba T, Yamamoto Y, Hamaoka S, Tsukahara-Tamai N, Ozawa Y, Tsuruoka A, Nara K, et al. Sulfonamide Derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin α2 subunit on endothelium. Cancer Res. 2002;62:6116-23.
19. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other diseases. Nat Med. 1995;1:27-31.
20. Folkman J. Endogenous angiogenesis inhibitors. APMIS. 2004;112:496-507.
21. Folkman J. Angiogenesis inhibitors: a new class of drugs. Cancer Biol Ther. 2003;2:S127-S33.
22. Sengupta A, Ghosh S, Bhattacharjee S, Das S. Indian food ingredients and cancer prevention - an experimental evaluation of anticarcinogenic effects of garlic in rat colon. Asian Pac J Cancer Prev. 2004;5:126-32.
23. Kyo E, Uda N, Kasuga S, Itakura Y. Immunomodulatory effects of aged garlic extract. J Nutr. 2001;131:1075S-9S.
24. Pinto JT, Lapsia S, Shah A, Santiago H, Kim G. Antiproliferative effects of garlic-derived and other allium related compounds. Adv Exp Med Biol. 2001;492:83-106.
25. Milner JA. Garlic: its anticarcinogenic and antitumorigenic properties. Nutr Rev. 1996;54:S82-6.