Membrane stabilization by intimate contact between cells reduces their Mg2+ activity and suppresses the neoplastic phenotype

Seminars in Cancer Biology

Volumn 15, Issue 2, 2005, Pages 121-131

  Rubin, Harry ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Contact inhibition; Growth factors; Growth regulation

Indexed keywords

MAGNESIUM;

CANCER CELL; CELL GROWTH; CELL STIMULATION; CELL TRANSFORMATION; DNA SYNTHESIS; GENE CONTROL; HUMAN; MEMBRANE TRANSPORT; NONHUMAN; PEPTIDE SYNTHESIS; PHENOTYPE; PROTEIN SYNTHESIS; REVIEW;

ANIMALS; CATIONS, DIVALENT; CELL COMMUNICATION; CELL MEMBRANE; CELL TRANSFORMATION, NEOPLASTIC; DNA REPLICATION; MAGNESIUM; PHENOTYPE; PROTEIN BIOSYNTHESIS;

EID: 12344306526     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcancer.2004.08.003     Document Type: Review

References (88)

1. M. Stoker Regulation of growth and orientation in hamster cells transformed by polyomavirus Virology 24 1964 165 174
2. M. Stoker, M. Shearer, and C. O'Neill Growth inhibition of polyoma-transformed cells by contact with static normal fibroblasts J. Cell Sci. 1 1966 297 310
3. H. Hennings, V.A. Robinson, D.M. Michael, G.R. Pettit, R. Jung, and S.H. Yuspa Development of an in vitro analogue of initiated mouse epidermis to study tumor promoters and antipromoters Cancer Res. 50 1990 4794 4800
4. H. Rubin Microenvironmental regulation of the initiated cell Adv. Cancer Res. 90 2003 1 62
5. J.E. Strickland, M. Ueda, H. Hennings, and S.H. Yuspa A model for initiated mouse skin: suppression of cells in grafts on athymic nude mice Cancer Res. 52 1992 1439 1444
6. A. Javaherian, M. Vaccariello, N.E. Fusenig, and J.A. Garlick Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium Cancer Res. 58 1998 2200 2208
7. H. Rubin, and R. Steiner Reversible alteration in the mitotic cycle of chick embryo cells in various states of growth regulation J. Cell. Physiol. 85 1975 261 270
8. J.B. Bolen, and G.L. Smith Effects of withdrawal of a mitogenic stimulus on progression of fibroblasts in S phase: differences between serum and purified multiplication-stimulating activity J. Cell. Physiol. 91 1977 441 448
9. R.F. Brooks Continuous protein synthesis is required to maintain the probability of entry into S phase Cell 12 1977 311 317
10. H. Rubin, and T. Koide Early cellular responses to diverse growth stimuli independent of protein and RNA synthesis J. Cell. Physiol. 86 1975 47 58
11. A. Hershko, P. Mamont, R. Shields, and G.T. Tomkins Pleiotypic response Nat. New Biol. 232 1971 1971
12. B.M. Sefton, and H. Rubin Stimulation of glucose transport in cultures of density-inhibited chick embryo cells Proc. Natl. Acad. Sci. U.S.A. 68 1971 3154 3157
13. J.H. Kim, A.S. Gelbard, and A.G. Perez Inhibition of DNA synthesis by actinomycin D and cycloheximide in synchronized HeLa cells Exp. Cell Res. 53 1968 478 487
14. C.P. Stanners, and H. Becker Control of macromolecular synthesis in proliferating and resting Syrian hamster cells in monolayer culture J. Cell. Physiol. 77 1971 31 42
15. E.M. Levine, Y. Becker, C.W. Boone, and H. Eagle Contact inhibition, macromolecular synthesis, and polyribosomes in cultured human diploid fibroblasts Proc. Natl. Acad. Sci. U.S.A. 53 1965 350 356
16. S. Cohen, and M. Stastny Epidermal growth factor III. The stimulation of polysome formation in chick embryo epidermis Biochim. Biophys. Acta 166 1968 427 437
17. M.H. Schreier, and T. Staehelin Initiation of mammalian protein synthesis: the importance of ribosome and initiation factor quality for the efficiency of in vitro systems J. Mol. Biol. 73 1973 329 349
18. M. Meselson, M. Nomura, S. Brenner, C. Davern, and D. Schlessinger Conservation of ribosomes during bacterial growth J. Mol. Biol. 9 1964 696 711
19. M. Revel, and H.H. Hiatt Magnesium requirement for the formation of an active messenger RNA-ribosome-S-RNA complex J. Mol. Biol. 11 1965 467 475
20. R.M.C. Dawson, and H. Hauser Binding of calcium to phospholipids A.W. Cuthbert Calcium and Cellular Function 1970 St. Martins Press New York 17 41
21. R.D. Grubbs Intracellular magnesium and magnesium buffering Biometals 15 2002 251 259
22. D. Garfinkel, and L. Garfinkel Magnesium and regulation of carbohydrate metabolism at the molecular level Magnesium 1 1988 249 261
23. E.J. Peck, and W.J. Ray Metal complexes of phosphoglucomutase in vivo J. Biol. Chem. 246 1971 1160 1167
24. L. Shlatz, and G.V. Marinetti Hormone-calcium interactions with the plasma membrane of rat liver cells Science 176 1972 175 177
25. A.P. Carvalho, H. Sanui, and N. Pace Calcium and magnesium binding properties of cell membrane materials J. Cell Comp. Physiol. 62 1963 311 317
26. H. Sanui, and N. Pace Effect of ATP, EDTA and EGTA on the simultaneous binding of Na, K, Mg and Ca by rat liver microsomes J. Cell. Physiol. 69 1967 11 20
27. T. Gurney Local stimulation of growth in primary cultures of chick embryo fibroblasts Proc. Natl. Acad. Sci. U.S.A. 62 1969 906 911
28. H. Rubin, and H. Sanui Complexes of inorganic pyrophosphate, orthophosphate and calcium as stimulants of 3T3 cells multiplication Proc. Natl. Acad. Sci. U.S.A. 74 1977 5025 5030
29. 2+ and pyrophosphate J. Cell. Physiol. 117 1983 51 61
30. H. Rubin, and T. Koide Stimulation of DNA synthesis and 2-deoxy-d-glucose transport in chick embryo cultures by excessive metal concentrations and by a carcinogenic hydrocarbon J. Cell. Physiol. 81 1973 387 396
31. H. Sanui, and H. Rubin Ionic changes associated with lead stimulation of DNA synthesis in Balb/c3T3 cells Biol. Trace Element Res. 6 1984 289 307
32. C. O'Neill, P. Jordan, and G. Ireland Evidence for two distinct mechanisms of anchorage stimulation in freshly explanted and 3T3 Swiss mouse fibroblasts Cell 44 1986 489 496
33. J. Schlessinger Signal transduction by allosteric receptor oligomerization Trends Biochem. Sci. 13 1988 443 447
34. A. Ullrich, and J. Schlessinger Signal transduction by receptors with tyrosine kinase activity Cell 61 1990 203 212
35. H. Hauser, and R.M.C. Dawson The displacement of calcium ions from phospholipid monolayers by pharmacologically active and other organic bases Biochem. J. 109 1968 909 916
36. H. Rubin Central role for magnesium in coordinate control of metabolism and growth in animal cells Proc. Natl. Acad. Sci. U.S.A. 72 1975 3551 3555
37. D.F. Bowen-Pope, and H. Rubin Magnesium and calcium effects on uptake of hexoses and uridine by chick embryo fibroblasts Proc. Natl. Acad. Sci. U.S.A. 74 1977 1585 1589
38. M. Terasaki, and H. Rubin Evidence that intracellular magnesium is present in cells at a regulatory concentration for protein synthesis Proc. Natl. Acad. Sci. U.S.A. 82 1985 7324 7326
39. H. Sanui, and H. Rubin Correlated effects of external magnesium on cation content and DNA synthesis in cultured chicken embryo fibroblasts J. Cell. Physiol. 92 1977 23 32
40. H. Rubin, M. Terasaki, and H. Sanui Major intracellular cations and growth control: correspondence among magnesium content, protein synthesis, and the onset of DNA synthesis in Balb/c 3T3 cells Proc. Natl. Acad. Sci. U.S.A. 76 1979 3917 3921
41. D.F. Bowen-Pope, C. Vidair, H. Sanui, and H. Rubin Separate roles for calcium and magnesium in their synergistic effect on uridine uptake by cultured cells Proc. Natl. Acad. Sci. U.S.A. 76 1979 1308 1312
42. 2+, on DNA synthesis and cell cation content in chick embryo fibroblasts J. Cell. Physiol. 101 1979 117 128
43. K. Vleminckx, and R. Kemler Cadherins and tissue formation: integrating adhesion and signaling BioEssays 21 1999 211 220
44. H. Sanui, and H. Rubin Membrane bound and cellular cationic changes associated with insulin stimulation of cultured cells J. Cell. Physiol. 96 1978 265 278
45. H. Sanui, and H. Rubin Changes of intracellular and externally bound cations accompanying serum stimulation of mouse Balb/c3T3 cells Exp. Cell Res. 139 1982 15 25
46. P.W. Flatman Magnesium transport across cell membranes J. Membr. Biol. 80 1984 1 14
47. 2+ homeostasis in BC3H-1 myocytes Am. J. Physiol. 1991 260
48. 2+- and tyrosine kinase-dependent mechanisms J. Biochem. 115 1994 730 737
49. A.M.P. Romani, and A. Scarpa Regulation of cellular magnesium Frontiers Biosci. 5 2000 720 734
50. 2+ homeostasis by TRPM7 Cell 114 2003 191 200
51. P.J. England, R.M. Denton, and P.J. Randle The influence of magnesium ions and other bivalent metal ions on the aconitase equilibrium and its bearing on the binding of magnesium ions by citrate in rat heart Biochem. J. 105 1967 32c 33c
52. I.A. Rose The state of magnesium in cells as estimated from the adenylate kinase equilibrium Proc. Natl. Acad. Sci. U.S.A. 61 1968 1079 1086
53. B.E. Corkey, J. Duszynski, T.L. Rich, B. Matschinsky, and J.R. Williamson Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria J. Biol. Chem. 261 1986 2567 2574
54. S.B. Horowitz, and Y.-T. Lau A function that relates protein synthetic rates to potassium activity in vivo J. Cell. Physiol. 135 1988 425 434
55. Y.-T. Lau, R.R. Yassin, and S.B. Horowitz Potassium salt microinjection into Xenopus oocytes mimics gonadotropin treatment Science 240 1988 1231 1323
56. S.B. Horowitz, and L.J.M. Tluczek Gonadotropin stimulates oocyte translation by increasing magnesium activity through intracellular potassium-magnesium exchange Proc. Natl. Acad. Sci. U.S.A. 86 1989 9652 9656
57. J.S. Cook Magnesium as an effector in an oocyte's response to gonadotropin News Physiol. Sci. 5 1990 41
58. B. Raju, E. Murphy, L.A. Levy, R.D. Hall, and R.E. London A fluorescent indicator for measuring cytosolic free magnesium Am. J. Physiol. 256 1989 C540 C548
59. 2+ concentration in single Swiss 3T3 fibroblasts Am. J. Physiol. 261 1991 C1074 C1080
60. P.B. Dennis, A. Jaeschke, M. Saitoh, B. Fowler, S.C. Kozma, and G. Thomas Mammalian TOR: a homeostatic ATP sensor Science 294 2001 1102 1105
61. D.W. Fodge, and H. Rubin Activation of phosphofructokinase by stimulants of cell multiplication Nat. New Biol. 246 1973 181 183
62. H. Rubin Magnesium deprivation reproduces the coordinate effects of serum removal or cortisol addition on transport and metabolism in chick embryo fibroblasts J. Cell. Physiol. 89 1976 613 626
63. N. Terada, H.R. Patel, K. Takase, K. Kohno, and A.C. Nairns Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins Proc. Natl. Acad. Sci. U.S.A. 91 1994 11477 11481
64. C. Carruthers, and V. Suntzeff Chemical studies on the mode of action of methylcholanthrene on mouse epidermis Cancer Res. 3 1943 744 748
65. R.P. deLong, D.R. Coman, and I. Zeidman The significance of low calcium and high potassium content in neoplastic tissue Cancer 3 1950 718 721
66. A.I. Lansing, T.B. Rosenthal, and M.D. Kamen Calcium ion exchanges in some normal tissues and in epidermal carcinogenesis Arch. Biochem. 19 1948 177 183
67. M. Terasaki Studies on magnesium in non-transformed and transformed Balb/c 3T3 cells. PhD dissertation 1983 University of California Berkeley, CA
68. H. Rubin, C. Vidair, and H. Sanui Restoration of normal appearance, growth behavior and calcium content to transformed 3T3 cells by magnesium deprivation Proc. Natl. Acad. Sci. U.S.A. 78 1981 2350 2354
69. D.R. Coman Decreased mutual adhesiveness, a property of cells from squamous cell carcinomas Cancer Res. 4 1944 625 629
70. M. McCutcheon, D.R. Coman, and F.B. Moore Studies on invasiveness of cancer. Adhesiveness of malignant cells in various human adenocarcinomas Cancer 1 1948 460 467
71. I. Zeidman Chemical factors in the mutual adhesiveness of epithelial cells Cancer Res. 7 1947 386 389
72. H. Sanui, and H. Rubin Membrane bound and cellular ion changes associated with serum stimulation of DNA synthesis in mouse 3T3 cells J. Cell Biol. 79 1978 84a
73. D.R. Coman, and T.F. Anderson A structural difference between surfaces of normal and of carcinomatous epidermal cells Cancer Res. 15 1955 541 543
74. G.B. Grunwald The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules Curr. Opin. Cell Biol. 5 1993 797 805
75. R. Umbas, J.A. Schalken, T.W. Aalders, B.S. Carter, H.F.M. Karthaus, and H.E. Schaafsma Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer Cancer Res. 52 1992 5104 5109
76. Y. Shimoyama, A. Nagafuchi, S. Fujita, M. Gotoh, M. Takeichi, and S. Tsukita Cadherin dysfunction in a human cell line: possible involvement of loss a a-catenin expression in reduced cell-cell adhesiveness Cancer Res. 52 1992 5770 5774
77. 2+ concentration Proc. Natl. Acad. Sci. U.S.A. 78 1981 328 332
78. W. McKeehan, and R.G. Ham Calcium and magnesium ions and the regulation of multiplication in normal and transformed cells Nature 275 1978 756 758
79. H. Rubin, and B. Chu Self-normalization of highly transformed 3T3 cells through maximized contact interaction Proc. Natl. Acad. Sci. U.S.A. 79 1982 1903 1907
80. P.P. Mehta, J.S. Bertram, and W.R. Loewenstein Growth inhibition of transformed cells correlates with their junctional communication with normal cells Cell 44 1986 187 196
81. H. Yamasaki, and C.C. Naus Role of connexin genes in growth control Carcinogenesis (London) 17 1996 1199 1213
82. D.B. Alexander, H. Ichikawa, J.F. Bechberger, V. Valiunas, M. Ohki, and C.C.G. Naus Normal cells control the growth of neighboring transformed cells independent of gap junctional communication and Src activity Cancer Res. 64 2004 1347 1358
83. 2+, protein synthesis and the phenotype of transformed Balb/c 3T3 cells J. Cell Biol. 91 1981 4a
84. 2+ in lymphocytes J. Cell Biol. 95 1982 189 196
85. R. Baserga The biology of cell reproduction 1985 Harvard University Press Boston
86. J.F. Whitfield The roles of calcium and magnesium in cell proliferation: An overview A. Boynton W.L. McKeehan J.F. Whitfield Ions, proliferation and cancer 1982 Academic Press New York 283 294
87. S. Benchimol, A. Fuks, S. Jothy, N. Beauchemin, K. Shirota, and C.P. Stanners Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule Cell 57 1989 327 334
88. R.A. Screaton, L. DeMarte, P. Dráber, and C.P. Stanners The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchor J. Cell Biol. 150 2000 613 625