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Volumn 37, Issue 5, 2018, Pages 757-764

Patient-centered precision health in a learning health care system: Geisinger's genomic medicine experience

(17)  Williams, Marc S a   Buchanan, Adam H a   Davis, F Daniel b   Faucett, W Andrew a   Hallquist, Miranda L G a   Leader, Joseph B c   Martin, Christa L d   McCormick, Cara Z a   Meyer, Michelle N e   Murray, Michael F a,f   Rahm, Alanna K a   Schwartz, Marci L B a   Sturm, Amy C a   Wagner, Jennifer K e   Williams, Janet L a   Willard, Huntington F g   Ledbetter, David H a  


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; GENOMICS; HEALTH CARE DELIVERY; HEALTH PROGRAM; HUMAN; KNOWLEDGE MANAGEMENT; LANDSCAPE; LEARNING; STORAGE; FEMALE; INTEGRATED HEALTH CARE SYSTEM; MALE; ORGANIZATION AND MANAGEMENT; PATIENT CARE; PERSONALIZED MEDICINE; PROGRAM DEVELOPMENT; PROGRAM EVALUATION; UNITED STATES;

EID: 85046798541     PISSN: 02782715     EISSN: 15445208     Source Type: Journal    
DOI: 10.1377/hlthaff.2017.1557     Document Type: Article
Times cited : (80)

References (26)
  • 1
    • 84941197175 scopus 로고    scopus 로고
    • Washington (DC): White House [cited 2018 Feb 27]
    • White House. The Precision Medicine Initiative [Internet]. Washington (DC): White House; [cited 2018 Feb 27]. Available from: https:// www.whitehouse.gov/precisionmedicine
    • The Precision Medicine Initiative [Internet]
  • 2
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015;372(9):793-5
    • (2015) N Engl J Med , vol.372 , Issue.9 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 4
    • 67649480496 scopus 로고    scopus 로고
    • The twin questions of personalized medicine: who are you and whom do you most resemble?
    • Kohane IS. The twin questions of personalized medicine: who are you and whom do you most resemble? Genome Med. 2009;1(1):4
    • (2009) Genome Med , vol.1 , Issue.1 , pp. 4
    • Kohane, I.S.1
  • 5
    • 84878837825 scopus 로고    scopus 로고
    • [Internet]. Washington (DC): IOM; c 2018 [cited 2018 Mar 21]
    • Institute of Medicine. The Learning Health System Series [Internet]. Washington (DC): IOM; c 2018 [cited 2018 Mar 21]. Available from: https://nam.edu/programs/valuescience-driven-health-care/learninghealth-system-series/
    • The Learning Health System Series
  • 8
    • 77953382007 scopus 로고    scopus 로고
    • Paulus, MD, MBA ProvenCare: Geisinger's model for care transformation through innovative clinical initiatives and value creation
    • Interview with Ronald A. Paulus, MD, MBA. ProvenCare: Geisinger's model for care transformation through innovative clinical initiatives and value creation. Am Health Drug Benefits. 2009;2(3):122-7
    • (2009) Am Health Drug Benefits , vol.2 , Issue.3 , pp. 122-127
  • 9
    • 84896318829 scopus 로고    scopus 로고
    • Implementation of genomic medicine in a health care delivery system: a value proposition?
    • Wade JE, Ledbetter DH, Williams MS. Implementation of genomic medicine in a health care delivery system: a value proposition?Am J Med Genet C Semin Med Genet. 2014;166C(1):112-6
    • (2014) Am J Med Genet C Semin Med Genet , vol.166C , Issue.1 , pp. 112-116
    • Wade, J.E.1    Ledbetter, D.H.2    Williams, M.S.3
  • 10
    • 84984945132 scopus 로고    scopus 로고
    • The Geisinger MyCode community health initiative: an electronic health record-linked biobank for precision medicine research
    • Carey DJ, Fetterolf SN, Davis FD, Faucett WA, Kirchner HL, Mirshahi U, et al. The Geisinger MyCode community health initiative: an electronic health record-linked biobank for precision medicine research. Genet Med. 2016;18(9): 906-13
    • (2016) Genet Med , vol.18 , Issue.9 , pp. 906-913
    • Carey, D.J.1    Fetterolf, S.N.2    Davis, F.D.3    Faucett, W.A.4    Kirchner, H.L.5    Mirshahi, U.6
  • 11
    • 85046754963 scopus 로고    scopus 로고
    • Danville (PA): Geisinger; 2018 Jan 1 [cited 2018 Feb 27]
    • Geisinger. MyCode® scorecard [Internet]. Danville (PA): Geisinger; 2018 Jan 1 [cited 2018 Feb 27]. Available from: https://www .geisinger.org/-/media/One Geisinger/pdfs/ghs/research/ mycode/scorecardinfographicjan2018. pdf?la=en&hash= 4B444A3649C7A849DC29DE5C56 DA9E55C8FE9383
  • 12
    • 85007028930 scopus 로고    scopus 로고
    • Distribution and clinical impact of functional variants in 50, 726 whole-exome sequences from the DiscovEHR study
    • Dewey FE, Murray MF, Overton JD, Habegger L, Leader JB, Fetterolf SN, et al. Distribution and clinical impact of functional variants in 50, 726 whole-exome sequences from the DiscovEHR study. Science. 2016; 354(6319)
    • (2016) Science , vol.354 , pp. 6319
    • Dewey, F.E.1    Murray, M.F.2    Overton, J.D.3    Habegger, L.4    Leader, J.B.5    Fetterolf, S.N.6
  • 13
    • 84960796985 scopus 로고    scopus 로고
    • How Geisinger made the case for an institutional duty to return genomic results to biobank participants
    • Faucett WA, Davis FD. How Geisinger made the case for an institutional duty to return genomic results to biobank participants. Appl Transl Genom. 2016;8:33-5
    • (2016) Appl Transl Genom , vol.8 , pp. 33-35
    • Faucett, W.A.1    Davis, F.D.2
  • 14
    • 85046763735 scopus 로고    scopus 로고
    • Precision engagement: the PMI's success will depend on more than genomes and big data
    • Oct 27. [Epub ahead of print]
    • Wagner JK, Peltz-Rauchman C, Rahm AK, Johnson CC. Precision engagement: the PMI's success will depend on more than genomes and big data. Genet Med. 2016 Oct 27. [Epub ahead of print]
    • (2016) Genet Med
    • Wagner, J.K.1    Peltz-Rauchman, C.2    Rahm, A.K.3    Johnson, C.C.4
  • 16
    • 85046768380 scopus 로고    scopus 로고
    • Bethesda (MD): National Center for Biotechnology Information; [cited 2018 Feb 27]
    • ClinVar [home page on the Internet]. Bethesda (MD): National Center for Biotechnology Information; [cited 2018 Feb 27]. Available from: https://www.ncbi.nlm.nih.gov/ clinvar/
  • 17
    • 85046708435 scopus 로고    scopus 로고
    • To access the appendix, click on the Details tab of the article online
    • To access the appendix, click on the Details tab of the article online
  • 18
    • 85036553089 scopus 로고    scopus 로고
    • Impact of a patient-facing enhanced genomic results report to improve understanding, engagement, and communication
    • 2017 Dec 4. [Epub ahead of print]
    • Williams JL, Rahm AK, Zallen DT, Stuckey H, Fultz K, Fan AL, et al. Impact of a patient-facing enhanced genomic results report to improve understanding, engagement, and communication. J Genet Couns. 2017 Dec 4. [Epub ahead of print]
    • J Genet Couns
    • Williams, J.L.1    Rahm, A.K.2    Zallen, D.T.3    Stuckey, H.4    Fultz, K.5    Fan, A.L.6
  • 19
    • 85010796460 scopus 로고    scopus 로고
    • Governance through privacy, fairness, and respect for individuals
    • Baker DB, Kaye J, Terry SF. Governance through privacy, fairness, and respect for individuals. EGEMS (Wash DC). 2016;4(2):1207
    • (2016) EGEMS (Wash DC) , vol.4 , Issue.2 , pp. 1207
    • Baker, D.B.1    Kaye, J.2    Terry, S.F.3
  • 20
    • 84937591383 scopus 로고    scopus 로고
    • Returning a research participant's genomic results to relatives: analysis and recommendations
    • Wolf SM, Branum R, Koenig BA, Petersen GM, Berry SA, Beskow LM, et al. Returning a research participant's genomic results to relatives: analysis and recommendations. J Law Med Ethics. 2015;43(3):440-63
    • (2015) J Law Med Ethics , vol.43 , Issue.3 , pp. 440-463
    • Wolf, S.M.1    Branum, R.2    Koenig, B.A.3    Petersen, G.M.4    Berry, S.A.5    Beskow, L.M.6
  • 21
    • 85046782714 scopus 로고    scopus 로고
    • [Internet]. Danville (PA): Geisinger; c 2018 [cited 2018 Mar 22]
    • Geisinger. MyCode conditions [Internet]. Danville (PA): Geisinger; c 2018 [cited 2018 Mar 22]. Available from: https://www.geisinger .org/mycode/mycode-conditions
    • MyCode conditions
  • 22
    • 85011835129 scopus 로고    scopus 로고
    • Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics
    • Kalia SS, Adelman K, Bale SJ, Chung WK, Eng C, Evans JP, et al. Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics. Genet Med. 2017;19(2):249-55
    • (2017) Genet Med , vol.19 , Issue.2 , pp. 249-255
    • Kalia, S.S.1    Adelman, K.2    Bale, S.J.3    Chung, W.K.4    Eng, C.5    Evans, J.P.6
  • 23
    • 85046823313 scopus 로고    scopus 로고
    • [Internet]. Danville (PA): Geisinger; 2018 Jan 1 [cited 2018 Feb 27]
    • Geisinger. MyCode® results returned [Internet]. Danville (PA): Geisinger; 2018 Jan 1 [cited 2018 Feb 27]. Available from: https://www .geisinger.org/-/media/ OneGeisinger/pdfs/ghs/research/ mycode/ror-table-jan2018.pdf
    • MyCode® results returned
  • 24
    • 85046745249 scopus 로고    scopus 로고
    • Danville (PA): Geisinger; 2017. News release, Geisinger launches National Precision Health Initiative; 2017 Nov 14 [cited 2018 Feb 27]
    • Geisinger [Internet]. Danville (PA): Geisinger; 2017. News release, Geisinger launches National Precision Health Initiative; 2017 Nov 14 [cited 2018 Feb 27]. Available from: https://www.geisinger.org/aboutgeisinger/ news-and-media/newsreleases/ 2017/11/15/13/58/ geisinger-launches-nationalprecision-health-initiative
  • 25
    • 85046832573 scopus 로고    scopus 로고
    • Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants
    • Oct 26. [Epub ahead of print]
    • Buchanan AH, Manickam K, Meyer MN, Wagner JK, Hallquist MLG, Williams JL, et al. Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants. Genet Med. 2017 Oct 26. [Epub ahead of print]
    • (2017) Genet Med
    • Buchanan, A.H.1    Manickam, K.2    Meyer, M.N.3    Wagner, J.K.4    Hallquist, M.L.G.5    Williams, J.L.6
  • 26
    • 84968865149 scopus 로고    scopus 로고
    • Convergence of implementation science, precision medicine, and the learning health care system: a new model for biomedical research
    • Chambers DA, Feero WG, Khoury MJ. Convergence of implementation science, precision medicine, and the learning health care system: a new model for biomedical research. JAMA. 2016;315(18):1941-2
    • (2016) JAMA , vol.315 , Issue.18 , pp. 1941-1942
    • Chambers, D.A.1    Feero, W.G.2    Khoury, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.