Implementation of genomic medicine in a health care delivery system: A value proposition?

American Journal of Medical Genetics, Part C: Seminars in Medical Genetics

Volumn 166, Issue 1, 2014, Pages 112-116

  Wade, Joanne E ^a   Ledbetter, David H ^b   Williams, Marc S ^c  

^a Strategic Program Development   (United States)

^b GEISINGER HEALTH SYSTEM   (United States)

^c INTERMOUNTAIN HEALTHCARE   (United States)

Author keywords

Genomic medicine; Healthcare delivery; Implementation; Innovation; Integrated healthcare delivery system; Personalized medicine; Reimbursement; Value

Indexed keywords

ADULT; ARTICLE; DECISION MAKING; EMPLOYER; FEMALE; GENOMICS; HEALTH CARE PERSONNEL; HUMAN; INTEGRATED HEALTH CARE SYSTEM; INVESTMENT; LEADERSHIP; MALE; PERSONALIZED MEDICINE; PRIORITY JOURNAL; REIMBURSEMENT; UNITED STATES;

GENOMIC MEDICINE; HEALTHCARE DELIVERY; IMPLEMENTATION; INNOVATION; INTEGRATED HEALTHCARE DELIVERY SYSTEM; PERSONALIZED MEDICINE; REIMBURSEMENT; VALUE;

DELIVERY OF HEALTH CARE; GENETICS, MEDICAL; GENOMICS; HUMANS; INDIVIDUALIZED MEDICINE; UNITED STATES;

EID: 84896318829     PISSN: 15524868     EISSN: 15524876     Source Type: Journal    
DOI: 10.1002/ajmg.c.31392     Document Type: Article

References (13)

1. Brooten D. 1997. Methodological issues linking costs and outcomes. Med Care 35:NS87-NS95.
2. Christensen CM, Grossman JH, Hwang J. 2009. The innovator's prescription a disruptive solution for healthcare. New York: McGraw Hill.
3. Genomic Medicine Institute. 2014. http://www.geisinger.org/research/centers_departments/genomics/index.html last accessed 1/17/2014.
4. Gerhard GS, Chu X, Wood GC, Gerhard GM, Benotti P, Petrick AT, Gabrielsen J, Strodel WE, Still CD, Argyropoulos G. 2012. Association of ghrelin receptor promoter polymorphisms with weight loss following Roux-en-Y gastric bypass surgery. Obes Surg 22:783-790.
5. Gerhard GS, Chu X, Wood GC, Gerhard GM, Benotti P, Petrick AT, Gabrielsen J, Strodel WE, Still CD, Argyropoulos G. 2013. Next-generation sequence analysis of genes associated with obesity and nonalcoholic fatty liver disease-related cirrhosis in extreme obesity. Hum Hered 75:144-151.
6. Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisolm RL, Chute CG, Connolly JJ, Crosslin D, Denny JC, Gallego CJ, Haines JL, Hakonarson H, Harley J, Jarvik GP, Kohane I, Kullo IJ, Larson EB, McCarty C, Ritchie MD, Roden D, Smith ME, Bottinger EP, Williams MS. 2013. The electronic medical records and genomics (eMERGE) network: Past, present and future. Genet Med 15:761-771.
7. Institute of Translational Health Sciences. 2014. https://www.iths.org/about/translational last accessed 1/17/2014.
8. Manolio TA, Chisolm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, Bick D, Bottinger E, Brilliant MH, Eng C, Frazer KA, Korf B, Ledbetter DH, Lupski JR, Marsh C, Mrazek D, Murray MF, O'Donnell PH, Rader D, Relling MV, Shuldiner AR, Valle D, Weinshilboum R, Green ED, Ginsburg GS. 2013. Implementing genomic medicine in the clinic: The future is here. Genet Med 15:258-267.
9. Pauker SG, Kassirer JP. 1987. N Engl J Med 316:250-258.
10. Porter ME. 2010. What is value in health care? N Engl J Med 363:2477-2481.
11. Still CD, Wood GC, Chu X, Erdman R, Manney CH, Benotti PN, Petrick AT, Strodel WE, Mirshahi UL, Mirshahi T, Carey DJ, Gerhard GS. 2011. High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery. Obesity (Silver Spring) 19:1676-1683.
12. Swindle R, Lukas CV, Meyer DA, Barnett PG, Hendricks AM. 1999. Cost analysis in the Department of veterans affairs: Consensus and future directions. Med Care 37:AS3-AS8.
13. Williams MS. 2014. Genomic medicine implementation: Learning by example. Am J Med Genet C 166C [information from the issue].