Role of the hydrophobic moiety of tumor promoters. Synthesis and activity of benzolactams with alkyl substituents at various positions

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 2, 1997, Pages 424-426

  Endo, Yasuyuki ^a   Ohno, Michihiro ^a   Takehana, Shunji ^a   Driedger, Paul E ^b   Stabel, Silvia ^c   Shudo, Koichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Procyon Pharmaceuticals Inc   (United States)

^c Max Delbruck Laboratorium der Max Planck Gesellschaft   (Germany)

Author keywords

benzolactam; hydrophobic interaction; structure activity relation; teleocidin; tumor promoter

Indexed keywords

BENZENE DERIVATIVE; LACTAM; TELEOCIDIN; TUMOR PROMOTER;

ALKYLATION; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; CONFORMATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYDROLYSIS; HYDROPHOBICITY; NITRATION; NUCLEAR MAGNETIC RESONANCE; RACEMIC MIXTURE; REDUCTION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR PROMOTION;

EID: 0030891965     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.424     Document Type: Article

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