The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress

Cell

Volumn 173, Issue 5, 2018, Pages 1265-1279.e19

  Zelikowsky, Moriel ^a   Hui, May ^a   Karigo, Tomomi ^a   Choe, Andrea ^a   Yang, Bin ^a   Blanco, Mario R ^a   Beadle, Keith ^a   Gradinaru, Viviana ^a   Deverman, Benjamin E ^a,c   Anderson, David J ^a,b  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

aggression; amygdala; BNST; DMH; fear; neuropeptides; Nk3R; NkB; social isolation; stress; Tac2

Indexed keywords

NEUROKININ B; OSANETANT; TACHYKININ; TACHYKININ 2; UNCLASSIFIED DRUG; ISOPROTEIN; NEUROLEPTIC AGENT; PREPROTACHYKININ; PROTEIN PRECURSOR; SMALL INTERFERING RNA; TACHYKININ RECEPTOR;

ADULT; AGGRESSION; ANIMAL TISSUE; ARTICLE; CHRONIC SOCIAL ISOLATION STRESS; CHRONIC STRESS; CONTROLLED STUDY; FEMALE; LIMIT OF QUANTITATION; MALE; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOCIAL ISOLATION; UPREGULATION; ADMINISTRATION AND DOSAGE; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BRAIN; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; GENE VECTOR; GENETICS; MENTAL STRESS; METABOLISM; NERVE CELL; PATHOLOGY; RNA INTERFERENCE;

ANIMALS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; BRAIN; FEMALE; GENETIC VECTORS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEUROKININ B; NEURONS; PROTEIN ISOFORMS; PROTEIN PRECURSORS; RECEPTORS, TACHYKININ; RNA INTERFERENCE; RNA, SMALL INTERFERING; SOCIAL ISOLATION; STRESS, PSYCHOLOGICAL; TACHYKININS; UP-REGULATION;

EID: 85046168529     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.03.037     Document Type: Article

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