Induced Pluripotent Stem Cell (iPSC)-derived extracellular vesicles are safer and more effective for cardiac repair than iPSCs

Circulation Research

Volumn 122, Issue 2, 2018, Pages 296-309

  Adamiak, Marta ^a   Cheng, Guangming ^b   Bobis Wozowicz, Sylwia ^a   Zhao, Lin ^b   Kedracka Krok, Sylwia ^a   Samanta, Anweshan ^b   Karnas, Elzbieta ^a,d   Xuan, Yu Ting ^b   Skupien Rabian, Bozena ^a,d   Chen, Xing ^b   Jankowska, Urszula ^d   Girgis, Magdy ^b   Sekula, Malgorzata ^d   Davani, Arash ^b   Lasota, Slawomir ^a   Vincent, Robert J ^b   Sarna, Michal ^a,d   Newell, Kathy L ^c   Wang, Ou Li ^b   Dudley, Nathaniel ^b   Madeja, Zbigniew ^a   Dawn, Buddhadeb ^b   Zuba Surma, Ewa K ^a   more..

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d Malopolska Centre for Biotechnology   (Poland)

Author keywords

Angiogenesis; Apoptosis; Extracellular vesicles; Induced pluripotent stem cells; Myocardial infarction; Remodeling; Stem cells

Indexed keywords

MICRORNA; PROTEIN;

ACUTE HEART INFARCTION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIAPOPTOTIC ACTIVITY; APOPTOSIS; ARTICLE; ATOMIC FORCE MICROSCOPY; C57BL 6 MOUSE; CAPILLARY DENSITY; CARDIAC MUSCLE CELL; CELL FUNCTION; CELL ISOLATION; CELL MIGRATION; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CENTRIFUGATION; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; ENDOTHELIUM CELL; EXOSOME; FLOW CYTOMETRY; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE MASS; HEART VENTRICLE REMODELING; IN VITRO STUDY; IN VIVO STUDY; INDUCED PLURIPOTENT STEM CELL; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SAFETY; STEM CELL CULTURE; STEM CELL TRANSPLANTATION; THERAPY EFFECT; TISSUE REPAIR; VASCULARIZATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; HEART INFARCTION; MALE; METABOLISM; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; TRANSPLANTATION; TREATMENT OUTCOME;

ANIMALS; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR VESICLES; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; TREATMENT OUTCOME;

EID: 85045777327     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.311769     Document Type: Article

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