Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

Cell Reports

Volumn 23, Issue 2, 2018, Pages 596-607

  Han, Julianna ^a   Perez, Jasmine T ^a   Chen, Cindy ^a   Li, Yan ^a   Benitez, Asiel ^b   Kandasamy, Matheswaran ^a   Lee, Yoontae ^c   Andrade, Jorge ^a   tenOever, Benjamin ^b   Manicassamy, Balaji ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

Capicua; cell intrinsic immunity; CIC; CRISPR Cas9 screen; GeCKO; H5N1; host factors; influenza virus; sialic acid pathway; SLC35A1

Indexed keywords

CASPASE 9; CRISPR ASSOCIATED PROTEIN; HOST FACTOR; SIALIC ACID; SLC35A1 PROTEIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; NUCLEOTIDE TRANSPORTER; SLC35A1 PROTEIN, HUMAN;

ARTICLE; BIOSYNTHESIS; CELLULAR IMMUNITY; CONTROLLED STUDY; GENOME-WIDE ASSOCIATION STUDY; HUMAN; HUMAN CELL; INFLUENZA A VIRUS (H5N1); INFLUENZA VIRUS; LUNG EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; SEQUENCE ANALYSIS; VIRUS ENTRY; VIRUS REPLICATION; VIRUS STRAIN; A-549 CELL LINE; CRISPR CAS SYSTEM; GENE KNOCKOUT; GENE LIBRARY; GENETICS; HUMAN GENOME; LENTIVIRUS; METABOLISM; PHYSIOLOGY; PROCEDURES;

A549 CELLS; CRISPR-CAS SYSTEMS; GENE KNOCKOUT TECHNIQUES; GENE LIBRARY; GENOME, HUMAN; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; LENTIVIRUS; NUCLEOTIDE TRANSPORT PROTEINS; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 85045214365     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2018.03.045     Document Type: Article

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