Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

BMC Cancer

Volumn 18, Issue 1, 2018, Pages

  Tsai, Susan ^a   McOlash, Laura ^a   Palen, Katie ^a   Johnson, Bryon ^a   Duris, Christine ^a   Yang, Qiuhui ^a   Dwinell, Michael B ^a   Hunt, Bryan ^a   Evans, Douglas B ^a   Gershan, Jill ^a   James, Michael A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

CAFs; Microenvironment; Organoid; Organotypic culture; Pancreatic Cancer; PDAC; TILs; Tumor immunology; Tumor stroma

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCITES; AUTOPSY; CANCER ASSOCIATED FIBROBLAST; CANCER SURGERY; CANCER TISSUE; CELL POLARITY; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; CYTOLOGY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; ORGANOID; PANCREAS CANCER; STROMA CELL; TUMOR CELL CULTURE; TUMOR MICROENVIRONMENT; TUMOR SPHEROID; TUMOR XENOGRAFT; CELL CULTURE TECHNIQUE; IMMUNOLOGY; IN VITRO STUDY; METABOLISM; MULTICELLULAR SPHEROID; PANCREAS TUMOR; PATHOLOGY; T LYMPHOCYTE; TUMOR CELL LINE;

CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; COCULTURE TECHNIQUES; HUMANS; IN VITRO TECHNIQUES; PANCREATIC NEOPLASMS; SPHEROIDS, CELLULAR; STROMAL CELLS; T-LYMPHOCYTES; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 85044523365     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-018-4238-4     Document Type: Article

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