메뉴 건너뛰기




Volumn 61, Issue 2, 2012, Pages 172-178

StellaTUM: Current consensus and discussion on pancreatic stellate cell research

(24)  Erkan, Mert a   Adler, Guido b   Apte, Minoti V c   Bachem, Max G d   Buchholz, Malte e   Detlefsen, Sönke f   Esposito, Irene a   Friess, Helmut a   Gress, Thomas M e   Habisch, Hans Joerg d   Hwang, Rosa F g   Jaster, Robert h   Kleeff, Jörg a   Klöppel, Günter a   Kordes, Claus i   Logsdon, Craig D g   Masamune, Atsushi j   Michalski, Christoph W a   Oh, Junseo k   Phillips, Phoebe A c   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GALACTOSIDE BINDING SOLUBLE 3; GALAPTIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NERVE GROWTH FACTOR; NITRIC OXIDE; PLATELET DERIVED GROWTH FACTOR; RANTES; STROMAL CELL DERIVED FACTOR 1; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UROKINASE;

EID: 84855201311     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-301220     Document Type: Review
Times cited : (338)

References (53)
  • 1
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 2008;88:125-72.
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 2
    • 33845998896 scopus 로고    scopus 로고
    • The pancreatic stellate cell: A star on the rise in pancreatic diseases
    • DOI 10.1172/JCI30082
    • Omary MB, Lugea A, Lowe AW, et al. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J Clin Invest 2007;117:50-9. (Pubitemid 46048449)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 50-59
    • Omary, M.B.1    Lugea, A.2    Lowe, A.W.3    Pandol, S.J.4
  • 3
    • 0020415180 scopus 로고
    • Morphological studies on a vitamin A-storing cell and its complex with macrophage observed in mouse pancreatic tissues following excess vitamin A administration
    • Watari N, Hotta Y, Mabuchi Y. Morphological studies on a vitamin A-storing cell and its complex with macrophage observed in mouse pancreatic tissues following excess vitamin A administration. Okajimas Folia Anat Jpn 1982;58:837-58.
    • (1982) Okajimas Folia Anat Jpn , vol.58 , pp. 837-858
    • Watari, N.1    Hotta, Y.2    Mabuchi, Y.3
  • 5
    • 5444247172 scopus 로고    scopus 로고
    • Identification, culture, and characterization of pancreatic stellate cells in rats and humans
    • Bachem MG, Schneider E, Gross H, et al. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998;115:421-32.
    • (1998) Gastroenterology , vol.115 , pp. 421-432
    • Bachem, M.G.1    Schneider, E.2    Gross, H.3
  • 6
    • 0019230284 scopus 로고
    • Perisinusoidal stellate cells (fat-storing cells, interstitial cell, lipocytes), their related structure in and around the liver sinusoids, and vitamin A storing cells in extrahepatic organs
    • Wake K. Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs. Int Rev Cytol 1980;66:303-53. (Pubitemid 10028209)
    • (1980) International Review of Cytology , vol.VOL. 66 , pp. 303-353
    • Wake, K.1
  • 7
    • 0026775513 scopus 로고
    • Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients
    • Pinzani M, Failli P, Ruocco C, et al. Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients. J Clin Invest 1992;90:642-6.
    • (1992) J Clin Invest , vol.90 , pp. 642-646
    • Pinzani, M.1    Failli, P.2    Ruocco, C.3
  • 8
    • 63349109309 scopus 로고    scopus 로고
    • Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development
    • Asahina K, Tsai SY, Li P, et al. Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development. Hepatology 2009;49:998-1011.
    • (2009) Hepatology , vol.49 , pp. 998-1011
    • Asahina, K.1    Tsai, S.Y.2    Li, P.3
  • 9
    • 0030778781 scopus 로고    scopus 로고
    • Development of hepatic sinusoidal structure with special reference to the ito cells
    • DOI 10.1002/(SICI)1097-0029(19971115)39:4<336::AID-JEMT4>3.0.CO;2-F
    • Enzan H, Himeno H, Hiroi M, et al. Development of hepatic sinusoidal structure with special reference to the Ito cells. Microsc Res Tech 1997;39:336-49. (Pubitemid 27522969)
    • (1997) Microscopy Research and Technique , vol.39 , Issue.4 , pp. 336-349
    • Enzan, H.1    Himeno, H.2    Hiroi, M.3    Kiyoku, H.4    Saibara, T.5    Onishi, S.6
  • 10
    • 33646149738 scopus 로고    scopus 로고
    • Hepatic stellate cells do not derive from the neural crest
    • Cassiman D, Barlow A, Vander Borght S, et al. Hepatic stellate cells do not derive from the neural crest. J Hepatol 2006;44:1098-104.
    • (2006) J Hepatol , vol.44 , pp. 1098-1104
    • Cassiman, D.1    Barlow, A.2    Vander Borght, S.3
  • 11
    • 0029587205 scopus 로고
    • Desmin expressing nonhematopoietic liver cells during rat liver development: An immunohistochemical and morphometric study
    • DOI 10.1046/j.1432-0436.1995.5940253.x
    • Kiassov AP, Van Eyken P, van Pelt JF, et al. Desmin expressing nonhematopoietic liver cells during rat liver development: an immunohistochemical and morphometric study. Differentiation 1995;59:253-8. (Pubitemid 26004223)
    • (1995) Differentiation , vol.59 , Issue.4 , pp. 253-258
    • Kiassov, A.P.1    Van Eyken, P.2    Van Pelt, J.F.3    Depla, E.4    Fevery, J.5    Desmet, V.J.6    Yap, P.S.H.7
  • 12
    • 0027409527 scopus 로고
    • Confocal microscopy immunofluorescence localization of desmin and other intermediate filament proteins in fetal rat livers
    • DOI 10.1016/0270-9139(93)90091-Z
    • Vassy J, Rigaut JP, Briane D, et al. Confocal microscopy immunofluorescence localization of desmin and other intermediate filament proteins in fetal rat livers. Hepatology 1993;17:293-300. (Pubitemid 23046703)
    • (1993) Hepatology , vol.17 , Issue.2 , pp. 293-300
    • Vassy, J.1    Rigaut, J.P.2    Briane, D.3    Kraemer, M.4
  • 13
    • 0036784417 scopus 로고    scopus 로고
    • Beauty is in the eye of the beholder: Emerging concepts and pitfalls in hepatic stellate cell research
    • Cassiman D, Roskams T. Beauty is in the eye of the beholder: emerging concepts and pitfalls in hepatic stellate cell research. J Hepatol 2002;37:527-35.
    • (2002) J Hepatol , vol.37 , pp. 527-535
    • Cassiman, D.1    Roskams, T.2
  • 14
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • DOI 10.1074/jbc.275.4.2247
    • Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-50. (Pubitemid 30081976)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.4 , pp. 2247-2250
    • Friedman, S.L.1
  • 17
    • 77951145570 scopus 로고    scopus 로고
    • Organ-, inflammationand cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells
    • Erkan M, Weis N, Pan Z, et al. Organ-, inflammationand cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells. Mol Cancer 2010;9:88.
    • (2010) Mol Cancer , vol.9 , pp. 88
    • Erkan, M.1    Weis, N.2    Pan, Z.3
  • 18
    • 79952240154 scopus 로고    scopus 로고
    • Septum transversum-derived mesothelium gives rise to hepatic stellate cells and werivascular mesenchymal cells in developing mouse liver
    • Asahina K, Zhou B, Pu WT, et al. Septum transversum-derived mesothelium gives rise to hepatic stellate cells and werivascular mesenchymal cells in developing mouse liver. Hepatology 2011;53:983-95.
    • (2011) Hepatology , vol.53 , pp. 983-995
    • Asahina, K.1    Zhou, B.2    Pu, W.T.3
  • 19
    • 70349422126 scopus 로고    scopus 로고
    • Negligible contribution of bone marrow-derived cells to collagen production during hepatic fibrogenesis in mice
    • Higashiyama R, Moro T, Nakao S, et al. Negligible contribution of bone marrow-derived cells to collagen production during hepatic fibrogenesis in mice. Gastroenterology 2009;137:1459-66 e1.
    • (2009) Gastroenterology , vol.137
    • Higashiyama, R.1    Moro, T.2    Nakao, S.3
  • 21
    • 77949269617 scopus 로고    scopus 로고
    • Bone marrow-derived pancreatic stellate cells in rats
    • Sparmann G, Kruse ML, Hofmeister-Mielke N, et al. Bone marrow-derived pancreatic stellate cells in rats. Cell Res 2010;20:288-98.
    • (2010) Cell Res , vol.20 , pp. 288-298
    • Sparmann, G.1    Kruse, M.L.2    Hofmeister-Mielke, N.3
  • 23
    • 79960465979 scopus 로고    scopus 로고
    • Epithelialemesenchymal transition in chronic liver disease: Fibrogenesis or escape from death?
    • Pinzani M. Epithelialemesenchymal transition in chronic liver disease: fibrogenesis or escape from death? J Hepatol 2011;55:459-65.
    • (2011) J Hepatol , vol.55 , pp. 459-465
    • Pinzani, M.1
  • 24
    • 70349338010 scopus 로고    scopus 로고
    • Hepatic and pancreatic stellate cells in focus
    • Kordes C, Sawitza I, Haussinger D. Hepatic and pancreatic stellate cells in focus. Biol Chem 2009;390:1003-12.
    • (2009) Biol Chem , vol.390 , pp. 1003-1012
    • Kordes, C.1    Sawitza, I.2    Haussinger, D.3
  • 25
    • 70349515743 scopus 로고    scopus 로고
    • The niche of stellate cells within rat liver
    • Sawitza I, Kordes C, Reister S, et al. The niche of stellate cells within rat liver. Hepatology 2009;50:1617-24.
    • (2009) Hepatology , vol.50 , pp. 1617-1624
    • Sawitza, I.1    Kordes, C.2    Reister, S.3
  • 26
    • 54549093685 scopus 로고    scopus 로고
    • Relationships among stellate cell activation, progenitor cells, and hepatic regeneration
    • Roskams T. Relationships among stellate cell activation, progenitor cells, and hepatic regeneration. Clin Liver Dis 2008;12:853-60; ix.
    • (2008) Clin Liver Dis , vol.12
    • Roskams, T.1
  • 27
    • 67650904758 scopus 로고    scopus 로고
    • Identification of a pancreatic stellate cell population with properties of progenitor cells: New role for stellate cells in the pancreas
    • Mato E, Lucas M, Petriz J, et al. Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas. Biochem J 2009;421:181-91.
    • (2009) Biochem J , vol.421 , pp. 181-191
    • Mato, E.1    Lucas, M.2    Petriz, J.3
  • 28
    • 77956075711 scopus 로고    scopus 로고
    • Isolation of quiescent human pancreatic stellate cells: A promising in vitro tool for studies of human pancreatic stellate cell biology
    • Vonlaufen A, Phillips PA, Yang L, et al. Isolation of quiescent human pancreatic stellate cells: a promising in vitro tool for studies of human pancreatic stellate cell biology. Pancreatology 2010;10:434-43.
    • (2010) Pancreatology , vol.10 , pp. 434-443
    • Vonlaufen, A.1    Phillips, P.A.2    Yang, L.3
  • 29
    • 78651097203 scopus 로고    scopus 로고
    • Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells
    • Haag C, Stadel D, Zhou S, et al. Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells. Gut 2011;60:225-37.
    • (2011) Gut , vol.60 , pp. 225-237
    • Haag, C.1    Stadel, D.2    Zhou, S.3
  • 30
    • 49749145668 scopus 로고    scopus 로고
    • Senescence of activated stellate cells limits liver fibrosis
    • Krizhanovsky V, Yon M, Dickins RA, et al. Senescence of activated stellate cells limits liver fibrosis. Cell 2008;134:657-67.
    • (2008) Cell , vol.134 , pp. 657-667
    • Krizhanovsky, V.1    Yon, M.2    Dickins, R.A.3
  • 31
    • 52149094275 scopus 로고    scopus 로고
    • The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma
    • Erkan M, Michalski CW, Rieder S, et al. The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Clin Gastroenterol Hepatol 2008;6:1155-61.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1155-1161
    • Erkan, M.1    Michalski, C.W.2    Rieder, S.3
  • 32
    • 65049091645 scopus 로고    scopus 로고
    • Signal transduction in pancreatic stellate cells
    • Masamune A, Shimosegawa T. Signal transduction in pancreatic stellate cells. J Gastroenterol 2009;44:249-60.
    • (2009) J Gastroenterol , vol.44 , pp. 249-260
    • Masamune, A.1    Shimosegawa, T.2
  • 33
    • 70349303936 scopus 로고    scopus 로고
    • Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin
    • Kim N, Yoo W, Lee J, et al. Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin. Gut 2009;58:1382-90.
    • (2009) Gut , vol.58 , pp. 1382-1390
    • Kim, N.1    Yoo, W.2    Lee, J.3
  • 35
    • 78049300013 scopus 로고    scopus 로고
    • Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion
    • Phillips PA, Yang L, Shulkes A, et al. Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion. Proc Natl Acad Sci U S A 2010;107:17397-402.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17397-17402
    • Phillips, P.A.1    Yang, L.2    Shulkes, A.3
  • 39
    • 3843149424 scopus 로고    scopus 로고
    • Fibrosis of the pancreas: The initial tissue damage and the resulting pattern
    • Kloppel G, Detlefsen S, Feyerabend B. Fibrosis of the pancreas: the initial tissue damage and the resulting pattern. Virchows Arch 2004;445:1-8. (Pubitemid 39044262)
    • (2004) Virchows Archiv , vol.445 , Issue.1 , pp. 1-8
    • Kloppel, G.1    Detlefsen, S.2    Feyerabend, B.3
  • 40
    • 0037302934 scopus 로고    scopus 로고
    • Rat pancreatic stellate cells secrete matrix metalloproteinases: Implications for extracellular matrix turnover
    • DOI 10.1136/gut.52.2.275
    • Phillips PA, McCarroll JA, Park S, et al. Rat pancreatic stellate cells secrete matrix metalloproteinases: implications for extracellular matrix turnover. Gut 2003;52:275-82. (Pubitemid 36115072)
    • (2003) Gut , vol.52 , Issue.2 , pp. 275-282
    • Phillips, P.A.1    McCarroll, J.A.2    Park, S.3    Wu, M.-J.4    Pirola, R.5    Korsten, M.6    Wilson, J.S.7    Apte, M.V.8
  • 42
    • 0030012970 scopus 로고    scopus 로고
    • Course of alcoholic chronic pancreatitis: A prospective clinicomorphological long-term study
    • DOI 10.1053/gast.1996.v111.pm8698203
    • Ammann RW, Heitz PU, Kloppel G. Course of alcoholic chronic pancreatitis: a prospective clinicomorphological long-term study. Gastroenterology 1996;111:224-31. (Pubitemid 26226903)
    • (1996) Gastroenterology , vol.111 , Issue.1 , pp. 224-231
    • Ammann, R.W.1    Heitz, P.U.2    Kloppel, G.3
  • 43
    • 33746297322 scopus 로고    scopus 로고
    • Fibrogenesis in alcoholic chronic pancreatitis: The role of tissue necrosis, macrophages, myofibroblasts and cytokines
    • DOI 10.1038/modpathol.3800613, PII 3800613
    • Detlefsen S, Sipos B, Feyerabend B, et al. Fibrogenesis in alcoholic chronic pancreatitis: the role of tissue necrosis, macrophages, myofibroblasts and cytokines. Mod Pathol 2006;19:1019-26. (Pubitemid 44106716)
    • (2006) Modern Pathology , vol.19 , Issue.8 , pp. 1019-1026
    • Detlefsen, S.1    Sipos, B.2    Feyerabend, B.3    Kloppel, G.4
  • 44
    • 78651101405 scopus 로고    scopus 로고
    • Withdrawal of alcohol promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats
    • Vonlaufen A, Phillips PA, Xu Z, et al. Withdrawal of alcohol promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats. Gut 2011;60:238-46.
    • (2011) Gut , vol.60 , pp. 238-246
    • Vonlaufen, A.1    Phillips, P.A.2    Xu, Z.3
  • 46
    • 65949114866 scopus 로고    scopus 로고
    • Cancerestellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma
    • Erkan M, Reiser-Erkan C, Michalski CW, et al. Cancerestellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma. Neoplasia 2009;11:497-508.
    • (2009) Neoplasia , vol.11 , pp. 497-508
    • Erkan, M.1    Reiser-Erkan, C.2    Michalski, C.W.3
  • 47
    • 56449092747 scopus 로고    scopus 로고
    • Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer
    • Masamune A, Kikuta K, Watanabe T, et al. Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol 2008;295: G709-17.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295
    • Masamune, A.1    Kikuta, K.2    Watanabe, T.3
  • 48
    • 78149315330 scopus 로고    scopus 로고
    • Role of pancreatic stellate cells in pancreatic cancer metastasis
    • Xu Z, Vonlaufen A, Phillips PA, et al. Role of pancreatic stellate cells in pancreatic cancer metastasis. Am J Pathol 2010;177:2585-96.
    • (2010) Am J Pathol , vol.177 , pp. 2585-2596
    • Xu, Z.1    Vonlaufen, A.2    Phillips, P.A.3
  • 49
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • Olive KP, Jacobetz MA, Davidson CJ, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009;324:1457-61.
    • (2009) Science , vol.324 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3
  • 50
    • 58149143021 scopus 로고    scopus 로고
    • Sonic hedgehog promotes desmoplasia in pancreatic cancer
    • Bailey JM, Swanson BJ, Hamada T, et al. Sonic hedgehog promotes desmoplasia in pancreatic cancer. Clin Cancer Res 2008;14:5995-6004.
    • (2008) Clin Cancer Res , vol.14 , pp. 5995-6004
    • Bailey, J.M.1    Swanson, B.J.2    Hamada, T.3
  • 52
    • 69249148349 scopus 로고    scopus 로고
    • Ras activity levels control the development of pancreatic diseases
    • Ji B, Tsou L, Wang H, et al. Ras activity levels control the development of pancreatic diseases. Gastroenterology 2009;137:1072-82; 82 e1e6.
    • (2009) Gastroenterology , vol.137
    • Ji, B.1    Tsou, L.2    Wang, H.3
  • 53
    • 34748822998 scopus 로고    scopus 로고
    • Hypothetical progression model of pancreatic cancer with origin in the centroacinar-acinar compartment
    • DOI 10.1097/mpa.0b013e31805d0190, PII 0000667620071000000003
    • Esposito I, Seiler C, Bergmann F, et al. Hypothetical progression model of pancreatic cancer with origin in the centroacinar-acinar compartment. Pancreas 2007;35:212-7. (Pubitemid 47482512)
    • (2007) Pancreas , vol.35 , Issue.3 , pp. 212-217
    • Esposito, I.1    Seiler, C.2    Bergmann, F.3    Kleeff, J.4    Friess, H.5    Schirmacher, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.