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Volumn 18, Issue 7, 2018, Pages e199-e210

Tuberculosis: advances and challenges in development of new diagnostics and biomarkers

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; TUBERCULOSTATIC AGENT;

EID: 85044277892     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(18)30111-7     Document Type: Review
Times cited : (254)

References (60)
  • 1
    • 85016170895 scopus 로고    scopus 로고
    • Global tuberculosis report, 2017
    • World Health Organization Geneva
    • WHO. Global tuberculosis report, 2017. 2017, World Health Organization, Geneva.
    • (2017)
  • 2
    • 79958256883 scopus 로고    scopus 로고
    • Strategic and technical advisory group for tuberculosis report of 10th meeting
    • World Health Organization Geneva
    • WHO. Strategic and technical advisory group for tuberculosis report of 10th meeting. 2010, World Health Organization, Geneva.
    • (2010)
  • 3
    • 85018538862 scopus 로고    scopus 로고
    • Chest radiography in tuberculosis detection. Summary of current WHO recommendations and guidance on programmatic approaches
    • World Health Organization Geneva
    • WHO. Chest radiography in tuberculosis detection. Summary of current WHO recommendations and guidance on programmatic approaches. 2016, World Health Organization, Geneva.
    • (2016)
  • 4
    • 84918799904 scopus 로고    scopus 로고
    • Xpert MTB/RIF assay for the diagnosis of pulmonary and extrapulmonary TB in adults and children
    • World Health Organization Geneva
    • WHO. Xpert MTB/RIF assay for the diagnosis of pulmonary and extrapulmonary TB in adults and children. 2017, World Health Organization, Geneva.
    • (2017)
  • 5
    • 85048775512 scopus 로고    scopus 로고
    • TB REACH Xpert budget estimation tool
    • (accessed Feb 23, 2018).
    • Stop TB Partnership. TB REACH Xpert budget estimation tool. http://www.stoptb.org/global/awards/tbreach/bet.asp (accessed Feb 23, 2018).
  • 6
    • 85048798368 scopus 로고    scopus 로고
    • UNITAID end-of-project evaluation: TB GeneXpert—scaling up access to contemporary diagnostics for TB
    • (accessed Feb 23, 2018).
    • Dalberg Global Development Advisors. UNITAID end-of-project evaluation: TB GeneXpert—scaling up access to contemporary diagnostics for TB. https://unitaid.eu/assets/TB-Xpert-Evaluation_Report-_Final.pdfl, January–March, 2017 (accessed Feb 23, 2018).
    • (2017)
  • 7
    • 84896285403 scopus 로고    scopus 로고
    • Feasibility of decentralised deployment of Xpert MTB/RIF test at lower level of health system in India
    • Raizada, N, Sachdeva, KS, Sreenivas, A, et al. Feasibility of decentralised deployment of Xpert MTB/RIF test at lower level of health system in India. PLoS One, 9, 2014, e89301.
    • (2014) PLoS One , vol.9 , pp. e89301
    • Raizada, N.1    Sachdeva, K.S.2    Sreenivas, A.3
  • 8
    • 85029160482 scopus 로고    scopus 로고
    • The New Xpert MTB/RIF Ultra: improving detection of Mycobacterium tuberculosis and resistance to rifampin in an assay suitable for point-of-care testing
    • Chakravorty, S, Simmons, AM, Rowneki, M, et al. The New Xpert MTB/RIF Ultra: improving detection of Mycobacterium tuberculosis and resistance to rifampin in an assay suitable for point-of-care testing. mBio 8 (2017), 00812–00817.
    • (2017) mBio , vol.8 , pp. 00812-00817
    • Chakravorty, S.1    Simmons, A.M.2    Rowneki, M.3
  • 9
    • 85035313153 scopus 로고    scopus 로고
    • Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study
    • Dorman, SE, Schumacher, SG, Alland, D, et al. Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study. Lancet Infect Dis 18 (2017), 76–84.
    • (2017) Lancet Infect Dis , vol.18 , pp. 76-84
    • Dorman, S.E.1    Schumacher, S.G.2    Alland, D.3
  • 10
    • 85030712884 scopus 로고    scopus 로고
    • WHO meeting report of a technical expert consultation: non-inferiority analysis of Xpert MTF/RIF Ultra compared to Xpert MTB/RIF
    • World Health Organization Geneva
    • WHO. WHO meeting report of a technical expert consultation: non-inferiority analysis of Xpert MTF/RIF Ultra compared to Xpert MTB/RIF. 2017, World Health Organization, Geneva.
    • (2017)
  • 11
    • 85029437937 scopus 로고    scopus 로고
    • Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study
    • Bahr, NC, Nuwagira, E, Evans, EE, et al. Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study. Lancet Infect Dis 18 (2017), 68–75.
    • (2017) Lancet Infect Dis , vol.18 , pp. 68-75
    • Bahr, N.C.1    Nuwagira, E.2    Evans, E.E.3
  • 12
    • 84961212860 scopus 로고    scopus 로고
    • Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic, parallel-group, multicountry, open-label, randomised controlled trial
    • Peter, JG, Zijenah, LS, Chanda, D, et al. Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic, parallel-group, multicountry, open-label, randomised controlled trial. Lancet 387 (2016), 1187–1197.
    • (2016) Lancet , vol.387 , pp. 1187-1197
    • Peter, J.G.1    Zijenah, L.S.2    Chanda, D.3
  • 13
    • 84961208947 scopus 로고    scopus 로고
    • The use of lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis and screening of active tuberculosis in people living with HIV. Policy update
    • World Health Organization Geneva
    • WHO. The use of lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis and screening of active tuberculosis in people living with HIV. Policy update. 2015, World Health Organization, Geneva.
    • (2015)
  • 14
    • 85011700195 scopus 로고    scopus 로고
    • Latent Mycobacterium tuberculosis infection and interferon-gamma release assays
    • Pai, M, Behr, M, Latent Mycobacterium tuberculosis infection and interferon-gamma release assays. Microbiol Spectr 4 (2016), 1–10.
    • (2016) Microbiol Spectr , vol.4 , pp. 1-10
    • Pai, M.1    Behr, M.2
  • 15
    • 85009742332 scopus 로고    scopus 로고
    • Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study
    • Dheda, K, Limberis, JD, Pietersen, E, et al. Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study. Lancet Respir Med 5 (2017), 269–281.
    • (2017) Lancet Respir Med , vol.5 , pp. 269-281
    • Dheda, K.1    Limberis, J.D.2    Pietersen, E.3
  • 16
    • 85048742436 scopus 로고    scopus 로고
    • Critical concentrations for drug susceptibility testing of medicines used in the treatment of drug-resistant tuberculosis
    • World Health Organization Geneva (accessed Feb 25, 2018).
    • WHO. Critical concentrations for drug susceptibility testing of medicines used in the treatment of drug-resistant tuberculosis. 2017, World Health Organization, Geneva https://www.finddx.org/publication/supplement-critical-concentrations-for-dst-for-tb-drugs/ (accessed Feb 25, 2018).
    • (2017)
  • 17
    • 84887367190 scopus 로고    scopus 로고
    • Tuberculosis, diagnostics technology landscape
    • May, 2017 5th edn. World Health Organization Geneva
    • Boyle, D, Tuberculosis, diagnostics technology landscape. May, 2017, 5th edn., 2017, World Health Organization, Geneva.
    • (2017)
    • Boyle, D.1
  • 18
    • 80053559963 scopus 로고    scopus 로고
    • Silent mutation in rpoB detected from clinical samples with rifampin-susceptible Mycobacterium tuberculosis
    • Moure, R, Martin, R, Alcaide, F, Silent mutation in rpoB detected from clinical samples with rifampin-susceptible Mycobacterium tuberculosis. J Clin Microbiol, 49, 2011, 3722.
    • (2011) J Clin Microbiol , vol.49 , pp. 3722
    • Moure, R.1    Martin, R.2    Alcaide, F.3
  • 19
    • 85043462793 scopus 로고    scopus 로고
    • A standardised method for interpreting the association between mutations and phenotypic drug-resistance in Mycobacterium tuberculosis
    • Miotto, P, Tessema, B, Tagliani, E, et al. A standardised method for interpreting the association between mutations and phenotypic drug-resistance in Mycobacterium tuberculosis. Eur Respir J, 50, 2017, 1701354.
    • (2017) Eur Respir J , vol.50 , pp. 1701354
    • Miotto, P.1    Tessema, B.2    Tagliani, E.3
  • 20
    • 85029577241 scopus 로고    scopus 로고
    • Evaluation of a rapid molecular drug-susceptibility test for tuberculosis
    • Xie, YL, Chakravorty, S, Armstrong, DT, et al. Evaluation of a rapid molecular drug-susceptibility test for tuberculosis. N Engl J Med 377 (2017), 1043–1054.
    • (2017) N Engl J Med , vol.377 , pp. 1043-1054
    • Xie, Y.L.1    Chakravorty, S.2    Armstrong, D.T.3
  • 21
    • 85040763196 scopus 로고    scopus 로고
    • Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
    • Coll, F, Phelan, J, Hill-Cawthorne, GA, et al. Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nat Genet 50 (2018), 307–316.
    • (2018) Nat Genet , vol.50 , pp. 307-316
    • Coll, F.1    Phelan, J.2    Hill-Cawthorne, G.A.3
  • 22
    • 85009452509 scopus 로고    scopus 로고
    • Removing the bottleneck in whole genome sequencing of Mycobacterium tuberculosis for rapid drug resistance analysis: a call to action
    • McNerney, R, Clark, TG, Campino, S, et al. Removing the bottleneck in whole genome sequencing of Mycobacterium tuberculosis for rapid drug resistance analysis: a call to action. Int J Infect Dis 56 (2017), 130–135.
    • (2017) Int J Infect Dis , vol.56 , pp. 130-135
    • McNerney, R.1    Clark, T.G.2    Campino, S.3
  • 23
    • 85033584713 scopus 로고    scopus 로고
    • Turnaround time of whole genome sequencing for mycobacterial identification and drug susceptibility testing in routine practice
    • published online Oct 10.
    • Olaru, ID, Patel, H, Kranzer, K, Perera, N, Turnaround time of whole genome sequencing for mycobacterial identification and drug susceptibility testing in routine practice. Clin Microbiol Infect, 2017 published online Oct 10. DOI:10.1016/j.cmi.2017.10.001.
    • (2017) Clin Microbiol Infect
    • Olaru, I.D.1    Patel, H.2    Kranzer, K.3    Perera, N.4
  • 24
    • 85048755853 scopus 로고    scopus 로고
    • The tuberculosis diagnostics pipeline
    • (accessed Feb 23, 2018).
    • Lessem, E, The tuberculosis diagnostics pipeline. http://www.pipelinereport.org/2017/tbdx, July, 2017 (accessed Feb 23, 2018).
    • (2017)
    • Lessem, E.1
  • 25
    • 85048843906 scopus 로고    scopus 로고
    • Dx Pipeline
    • (accessed Feb 23, 2018).
    • FIND. Dx Pipeline. https://www.finddx.org/dx-pipeline-status/ (accessed Feb 23, 2018).
  • 26
    • 85038430523 scopus 로고    scopus 로고
    • Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity
    • Paris, L, Magni, R, Zaidi, F, et al. Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity. Sci Transl Med, 9, 2017, eaal2807.
    • (2017) Sci Transl Med , vol.9 , pp. eaal2807
    • Paris, L.1    Magni, R.2    Zaidi, F.3
  • 27
    • 85020227169 scopus 로고    scopus 로고
    • Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring
    • Liu, C, Zhao, Z, Fan, J, et al. Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring. Proc Natl Acad Sci USA 114 (2017), 3969–3974.
    • (2017) Proc Natl Acad Sci USA , vol.114 , pp. 3969-3974
    • Liu, C.1    Zhao, Z.2    Fan, J.3
  • 28
    • 85048837658 scopus 로고    scopus 로고
    • GLI quick guide to TB diagnostics connectivity solution
    • (accessed Feb 23, 2018).
    • Global Laboratory Initiative. GLI quick guide to TB diagnostics connectivity solution. http://www.stoptb.org/wg/gli/assets/documents/gli_connectivity_guide.pdf, October, 2016 (accessed Feb 23, 2018).
    • (2016)
  • 29
    • 82155181351 scopus 로고    scopus 로고
    • Commercial serodiagnostic tests for diagnosis of tuberculosis
    • World Health Organization Geneva
    • WHO. Commercial serodiagnostic tests for diagnosis of tuberculosis. 2011, World Health Organization, Geneva.
    • (2011)
  • 30
    • 84975914135 scopus 로고    scopus 로고
    • A blood RNA signature for tuberculosis disease risk: a prospective cohort study
    • Zak, DE, Penn-Nicholson, A, Scriba, TJ, et al. A blood RNA signature for tuberculosis disease risk: a prospective cohort study. Lancet 387 (2016), 2312–2322.
    • (2016) Lancet , vol.387 , pp. 2312-2322
    • Zak, D.E.1    Penn-Nicholson, A.2    Scriba, T.J.3
  • 31
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry, MP, Graham, CM, McNab, FW, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466 (2010), 973–977.
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3
  • 32
    • 84931562172 scopus 로고    scopus 로고
    • A real-time PCR signature to discriminate between tuberculosis and other pulmonary diseases
    • Laux da Costa, L, Delcroix, M, Dalla Costa, ER, et al. A real-time PCR signature to discriminate between tuberculosis and other pulmonary diseases. Tuberculosis (Edinb) 95 (2015), 421–425.
    • (2015) Tuberculosis (Edinb) , vol.95 , pp. 421-425
    • Laux da Costa, L.1    Delcroix, M.2    Dalla Costa, E.R.3
  • 33
    • 84886613855 scopus 로고    scopus 로고
    • Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study
    • Kaforou, M, Wright, VJ, Oni, T, et al. Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study. PLoS Med, 10, 2013, e1001538.
    • (2013) PLoS Med , vol.10 , pp. e1001538
    • Kaforou, M.1    Wright, V.J.2    Oni, T.3
  • 34
    • 84895926841 scopus 로고    scopus 로고
    • Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity
    • Sutherland, JS, Loxton, AG, Haks, MC, et al. Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity. Clin Microbiol Infect 20 (2014), O230–O238.
    • (2014) Clin Microbiol Infect , vol.20 , pp. O230-O238
    • Sutherland, J.S.1    Loxton, A.G.2    Haks, M.C.3
  • 35
    • 84957943318 scopus 로고    scopus 로고
    • Concise gene signature for point-of-care classification of tuberculosis
    • Maertzdorf, J, McEwen, G, Weiner, J 3rd, et al. Concise gene signature for point-of-care classification of tuberculosis. EMBO Mol Med 8 (2016), 86–95.
    • (2016) EMBO Mol Med , vol.8 , pp. 86-95
    • Maertzdorf, J.1    McEwen, G.2    Weiner, J.3
  • 36
    • 85048739581 scopus 로고    scopus 로고
    • How much does it cost to launch and commercialize a companion diagnostic test?
    • (accessed Dec 12, 2017).
    • Diaceutics. How much does it cost to launch and commercialize a companion diagnostic test?. http://www.diaceutics.com/2016/08/31/how-much-does-it-cost-to-launch-and-commercialize-a-companion-diagnostic-test/, Aug 31, 2016 (accessed Dec 12, 2017).
    • (2016)
  • 37
    • 85028363481 scopus 로고    scopus 로고
    • Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study
    • Yoon, C, Semitala, FC, Atuhumuza, E, et al. Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study. Lancet Infect Dis 7 (2017), 1285–1292.
    • (2017) Lancet Infect Dis , vol.7 , pp. 1285-1292
    • Yoon, C.1    Semitala, F.C.2    Atuhumuza, E.3
  • 38
    • 84897935738 scopus 로고    scopus 로고
    • Beyond the IFN-γ horizon: biomarkers for immunodiagnosis of infection with Mycobacterium tuberculosis
    • Chegou, NN, Heyckendorf, J, Walzl, G, Lange, C, Ruhwald, M, Beyond the IFN-γ horizon: biomarkers for immunodiagnosis of infection with Mycobacterium tuberculosis. Eur Respir J 43 (2014), 1472–1486.
    • (2014) Eur Respir J , vol.43 , pp. 1472-1486
    • Chegou, N.N.1    Heyckendorf, J.2    Walzl, G.3    Lange, C.4    Ruhwald, M.5
  • 39
    • 85030121578 scopus 로고    scopus 로고
    • Discovery and validation of a six-marker serum protein signature for the diagnosis of active pulmonary tuberculosis
    • De Groote, MA, Sterling, DG, Hraha, T, et al. Discovery and validation of a six-marker serum protein signature for the diagnosis of active pulmonary tuberculosis. J Clin Microbiol 55 (2017), 3057–3071.
    • (2017) J Clin Microbiol , vol.55 , pp. 3057-3071
    • De Groote, M.A.1    Sterling, D.G.2    Hraha, T.3
  • 41
    • 84864612118 scopus 로고    scopus 로고
    • Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients
    • Weiner, J 3rd, Parida, SK, Maertzdorf, J, et al. Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients. PLoS One, 7, 2012, e40221.
    • (2012) PLoS One , vol.7 , pp. e40221
    • Weiner, J.1    Parida, S.K.2    Maertzdorf, J.3
  • 42
    • 84875806423 scopus 로고    scopus 로고
    • New sputum metabolite markers implicating adaptations of the host to Mycobacterium tuberculosis, and vice versa
    • du Preez, I, Loots, DT, New sputum metabolite markers implicating adaptations of the host to Mycobacterium tuberculosis, and vice versa. Tuberculosis (Edinb) 93 (2013), 330–337.
    • (2013) Tuberculosis (Edinb) , vol.93 , pp. 330-337
    • du Preez, I.1    Loots, D.T.2
  • 43
    • 84908048654 scopus 로고    scopus 로고
    • Plasma metabolomics in human pulmonary tuberculosis disease: a pilot study
    • Frediani, JK, Jones, DP, Tukvadze, N, et al. Plasma metabolomics in human pulmonary tuberculosis disease: a pilot study. PLoS One, 9, 2014, e108854.
    • (2014) PLoS One , vol.9 , pp. e108854
    • Frediani, J.K.1    Jones, D.P.2    Tukvadze, N.3
  • 44
    • 84947782969 scopus 로고    scopus 로고
    • Metabolomic profiling of plasma from patients with tuberculosis by use of untargeted mass spectrometry reveals novel biomarkers for diagnosis
    • Lau, SK, Lee, KC, Curreem, SO, et al. Metabolomic profiling of plasma from patients with tuberculosis by use of untargeted mass spectrometry reveals novel biomarkers for diagnosis. J Clin Microbiol 53 (2015), 3750–3759.
    • (2015) J Clin Microbiol , vol.53 , pp. 3750-3759
    • Lau, S.K.1    Lee, K.C.2    Curreem, S.O.3
  • 45
    • 84895875539 scopus 로고    scopus 로고
    • Identification of serum microRNA biomarkers for tuberculosis using RNA-seq
    • Zhang, H, Sun, Z, Wei, W, et al. Identification of serum microRNA biomarkers for tuberculosis using RNA-seq. PLoS One, 9, 2014, e88909.
    • (2014) PLoS One , vol.9 , pp. e88909
    • Zhang, H.1    Sun, Z.2    Wei, W.3
  • 46
    • 84926432088 scopus 로고    scopus 로고
    • A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis
    • Latorre, I, Leidinger, P, Backes, C, et al. A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis. Eur Respir J 45 (2015), 1173–1176.
    • (2015) Eur Respir J , vol.45 , pp. 1173-1176
    • Latorre, I.1    Leidinger, P.2    Backes, C.3
  • 47
    • 85029529708 scopus 로고    scopus 로고
    • Characterization of a novel panel of plasma microRNAs that discriminates between Mycobacterium tuberculosis infection and healthy individuals
    • Cui, JY, Liang, HW, Pan, XL, et al. Characterization of a novel panel of plasma microRNAs that discriminates between Mycobacterium tuberculosis infection and healthy individuals. PLoS One, 12, 2017, e0184113.
    • (2017) PLoS One , vol.12 , pp. e0184113
    • Cui, J.Y.1    Liang, H.W.2    Pan, X.L.3
  • 48
    • 85036553506 scopus 로고    scopus 로고
    • Sequential inflammatory processes define human progression from M tuberculosis infection to tuberculosis disease
    • Scriba, TJ, Penn-Nicholson, A, Shankar, S, et al. Sequential inflammatory processes define human progression from M tuberculosis infection to tuberculosis disease. PLoS Pathog, 13, 2017, e1006687.
    • (2017) PLoS Pathog , vol.13 , pp. e1006687
    • Scriba, T.J.1    Penn-Nicholson, A.2    Shankar, S.3
  • 49
    • 78751648792 scopus 로고    scopus 로고
    • Human gene expression profiles of susceptibility and resistance in tuberculosis
    • Maertzdorf, J, Repsilber, D, Parida, SK, et al. Human gene expression profiles of susceptibility and resistance in tuberculosis. Genes Immun 12 (2011), 15–22.
    • (2011) Genes Immun , vol.12 , pp. 15-22
    • Maertzdorf, J.1    Repsilber, D.2    Parida, S.K.3
  • 50
    • 84881104975 scopus 로고    scopus 로고
    • Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers
    • Bloom, CI, Graham, CM, Berry, MP, et al. Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers. PLoS One, 8, 2013, e70630.
    • (2013) PLoS One , vol.8 , pp. e70630
    • Bloom, C.I.1    Graham, C.M.2    Berry, M.P.3
  • 51
    • 84899709556 scopus 로고    scopus 로고
    • Diagnosis of childhood tuberculosis and host RNA expression in Africa
    • Anderson, ST, Kaforou, M, Brent, AJ, et al. Diagnosis of childhood tuberculosis and host RNA expression in Africa. N Engl J Med 370 (2014), 1712–1723.
    • (2014) N Engl J Med , vol.370 , pp. 1712-1723
    • Anderson, S.T.1    Kaforou, M.2    Brent, A.J.3
  • 52
    • 0037006639 scopus 로고    scopus 로고
    • The architecture of diagnostic research
    • Sackett, DL, Haynes, RB, The architecture of diagnostic research. BMJ 324 (2002), 539–541.
    • (2002) BMJ , vol.324 , pp. 539-541
    • Sackett, D.L.1    Haynes, R.B.2
  • 53
    • 84966415358 scopus 로고    scopus 로고
    • Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB
    • Chegou, NN, Sutherland, JS, Malherbe, S, et al. Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB. Thorax 71 (2016), 785–794.
    • (2016) Thorax , vol.71 , pp. 785-794
    • Chegou, N.N.1    Sutherland, J.S.2    Malherbe, S.3
  • 54
    • 84885206980 scopus 로고    scopus 로고
    • 1 H NMR spectroscopy-based metabolomics to sera of tuberculosis patients
    • 1 H NMR spectroscopy-based metabolomics to sera of tuberculosis patients. J Proteome Res 12 (2013), 4642–4649.
    • (2013) J Proteome Res , vol.12 , pp. 4642-4649
    • Zhou, A.1    Ni, J.2    Xu, Z.3
  • 55
    • 84893184836 scopus 로고    scopus 로고
    • A metabolic biosignature of early response to anti-tuberculosis treatment
    • Mahapatra, S, Hess, AM, Johnson, JL, et al. A metabolic biosignature of early response to anti-tuberculosis treatment. BMC Infect Dis, 14, 2014, 53.
    • (2014) BMC Infect Dis , vol.14 , pp. 53
    • Mahapatra, S.1    Hess, A.M.2    Johnson, J.L.3
  • 56
    • 85022337290 scopus 로고    scopus 로고
    • 1 H-nuclear magnetic resonance spectroscopy metabolic profiles in tuberculous, malignant and transudative pleural effusion
    • 1 H-nuclear magnetic resonance spectroscopy metabolic profiles in tuberculous, malignant and transudative pleural effusion. Mol Med Rep 16 (2017), 1147–1156.
    • (2017) Mol Med Rep , vol.16 , pp. 1147-1156
    • Wang, C.1    Peng, J.2    Kuang, Y.3    Zhang, J.4    Dai, L.5
  • 57
    • 85034644707 scopus 로고    scopus 로고
    • Integration of metabolomics and transcriptomics reveals a complex diet of Mycobacterium tuberculosis during early macrophage infection
    • Zimmermann, M, Kogadeeva, M, Gengenbacher, M, et al. Integration of metabolomics and transcriptomics reveals a complex diet of Mycobacterium tuberculosis during early macrophage infection. mSystems 2 (2017), e00057–e00117.
    • (2017) mSystems , vol.2 , pp. e00057-e00117
    • Zimmermann, M.1    Kogadeeva, M.2    Gengenbacher, M.3
  • 59
    • 84924285037 scopus 로고    scopus 로고
    • High-priority target product profiles for new tuberculosis diagnostics: report of a consensus meeting
    • World Health Organization Geneva
    • WHO. High-priority target product profiles for new tuberculosis diagnostics: report of a consensus meeting. 2014, World Health Organization, Geneva.
    • (2014)
  • 60
    • 85040783164 scopus 로고    scopus 로고
    • Moscow Declaration to End TB
    • (accessed Feb 25, 2018).
    • WHO. Moscow Declaration to End TB. http://www.who.int/tb/features_archive/Moscow_Declaration_to_End_TB_final_ENGLISH.pdf?ua=1, Nov 16–17, 2017 (accessed Feb 25, 2018).
    • (2017)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.