A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis

European Respiratory Journal

Volumn 45, Issue 4, 2015, Pages 1173-1176

  Latorre, Irene ^a,b,c   Leidinger, Petra ^a   Backes, Christina ^a   Domínguez, Jose ^c,d,e   De Souza Galvão, Maria Luiza ^f   Maldonado, Jose ^g   Prat, Cristina ^c,d,e   Ruiz Manzano, Juan ^c,d,e   Sánchez, Francisca ^h   Casas, Irma ^d,e   Keller, Andreas ^a   Von Briesen, Hagen ⁱ   Knobel, Hernando ^e,h   Meese, Eckart ^a   Meyerhans, Andreas ^b,j  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^e UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^f Unitat Neurovascular Hospital Vall d'Hebron   (Spain)

^g Barcelona Clinic   (Spain)

^h HOSPITAL DEL MAR   (Spain)

ⁱ FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^j INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MICRORNA 101; MICRORNA 146A; MICRORNA 148A; MICRORNA 150; MICRORNA 16; MICRORNA 192; MICRORNA 193A 5P; MICRORNA 194; MICRORNA 21; MICRORNA 22; MICRORNA 223; MICRORNA 25; MICRORNA 29C; MICRORNA 30E; MICRORNA 320B; MICRORNA 365; MICRORNA 378; MICRORNA 451; MICRORNA 483 5P; MICRORNA 532 5P; MICRORNA 590 5P; MICRORNA 660; MICRORNA 885 5P; MICRORNA LET 7E; UNCLASSIFIED DRUG;

BACTERIUM CULTURE; BLOOD ANALYSIS; CONTROLLED STUDY; DOWN REGULATION; HUMAN; LATENT TUBERCULOSIS INFECTION; LETTER; LUNG TUBERCULOSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SPAIN; TUBERCULIN TEST; TUBERCULOSIS; TUBERCULOSIS RAPID TEST; UPREGULATION; ADULT; BLOOD; CASE CONTROL STUDY; CLINICAL TRIAL; COMPARATIVE STUDY; FEMALE; ISOLATION AND PURIFICATION; LATENT TUBERCULOSIS; MALE; MICROBIOLOGICAL EXAMINATION; MIDDLE AGED; MULTICENTER STUDY; MYCOBACTERIUM TUBERCULOSIS; PROCEDURES; SENSITIVITY AND SPECIFICITY; TIME; TUBERCULOSIS, PULMONARY;

ADULT; BACTERIOLOGICAL TECHNIQUES; BIOMARKERS; CASE-CONTROL STUDIES; FEMALE; HUMANS; LATENT TUBERCULOSIS; MALE; MICRORNAS; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SPAIN; TIME FACTORS; TUBERCULOSIS, PULMONARY;

EID: 84926432088     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00221514     Document Type: Letter

References (15)

1. Walzl G, Ronacher K, Hanekom W, et al. Immunological biomarkers of tuberculosis. Nat Rev Immunol 2011; 11: 343-354.
2. Huang Y, Shen XJ, Zou Q, et al. Biological functions of microRNAs: a review. J Physiol Biochem 2011; 67: 129-139.
3. Leidinger P, Keller A, Backes C, et al. MicroRNA expression changes after lung cancer resection: a follow-up study. RNA Biology 2012; 9: 900-910.
4. Fu Y, Yi Z, Wu X, et al. Circulating microRNAs in patients with active pulmonary tuberculosis. J Clin Microbiol 2011; 49: 4246-4251.
5. Wu J, Lu C, Diao N, et al. Analysis of microRNA expression profiling identifies miR-155 and miR-155∗as potential diagnostic markers for active tuberculosis: a preliminary study. Hum Immunol 2011; 73: 31-37.
6. Maertzdorf J, Weiner JIII, Mollenkopf HJ, et al. Common patterns and disease-related signatures in tuberculosis and sarcoidosis. Proc Natl Acad Sci USA 2012; 109: 7853-7858.
7. Miotto P, Mwangoka G, Valente IC, et al. miRNA signatures in sera of patients with active pulmonary tuberculosis. PLoS One 2013; 8: e80149.
8. Zhang X, Guo J, Fan S, et al. Screening and identification of six serum microRNAs as novel potential combination biomarkers for pulmonary tuberculosis diagnosis. PLoS One 2013; 8: e81076.
9. Mestdagh P, Hartmann N, Baeriswyl L, et al. Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study. Nat Methods 2014; 11: 809-815.
10. Ma F, Xu S, Liu X, et al. The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma. Nat Immunol 2011; 12: 861-869.
11. Wu Z, Lu H, Sheng J, et al. Inductive microRNA-21 impairs anti-mycobacterial responses by targeting IL-12 and Bcl-2. FEBS Letters 2012; 586: 2459-2467.
12. Krutzfeldt J, Rosch N, Hausser J, et al. MicroRNA-194 is a target of transcription factor 1 (Tcf1, HNF1alpha) in adult liver and controls expression of frizzled-6. Hepatology 2012; 55: 98-107.
13. Schaale K, Neumann J, Schneider D, et al. Wnt signaling in macrophages: augmenting and inhibiting mycobacteria-induced inflammatory responses. Eur J Cell Biol 2011; 90: 553-559.
14. Bezman NA, Chakraborty T, Bender T, et al. miR-150 regulates the development of NK and iNKT cells. J Exp Med 2011; 208: 2717-2731.
15. Keller A, Leidinger P, Bauer A, et al. Toward the blood-borne miRNome of human diseases. Nat Methods 2011; 8: 841-843.