Silent mutation in rpoB detected from clinical samples with rifampin-susceptible Mycobacterium tuberculosis

Journal of Clinical Microbiology

Volumn 49, Issue 10, 2011, Pages 3722-

  Moure, Raquel ^a   Martín, Rogelio ^a   Alcaide, Fernando ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMPICIN; RNA POLYMERASE BETA SUBUNIT;

ANTIBIOTIC SENSITIVITY; BACTERIAL GENE; BACTERIUM CULTURE; BACTERIUM ISOLATE; DNA HYBRIDIZATION; GENE MUTATION; LETTER; MOLECULAR PROBE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RPOB GENE;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DIAGNOSTIC ERRORS; DRUG RESISTANCE, BACTERIAL; HUMANS; MUTATION, MISSENSE; MYCOBACTERIUM TUBERCULOSIS; RIFAMPIN;

MYCOBACTERIUM TUBERCULOSIS;

EID: 80053559963     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.05314-11     Document Type: Letter

References (6)

1. Alonso, M., et al. 2011. Isolation of Mycobacterium tuberculosis strains with a silent mutation in rpoB leading to potential misassignment of resistance category. J. Clin. Microbiol. 49:2688-2690.
2. Boehme, C. C., et al. 2011. Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. Lancet 377: 1495-1505.
3. Moure, R., et al. 2011. Rapid detection of Mycobacterium tuberculosis complex and rifampin resistance in smear-negative clinical samples by use of an integrated real-time PCR method. J. Clin. Microbiol. 49:1137-1139.
4. WHO. 2010. Multidrug and extensively drug-resistant TB (M/XDR-TB). 2010 Global report on surveillance and response. World Health Organization, Geneva, Switzerland.
5. WHO. 2011. Rapid implementation of the Xpert MTB/RIF diagnostic test. Technical and operational 'how to.' Practical considerations. World Health Organization, Geneva, Switzerland.
6. WHO. 2010. Treatment of tuberculosis guidelines, 4th ed. World Health Organization, Geneva, Switzerland.