Rapid estrogen receptor-α signaling mediated by ERK activation regulates vascular tone in male and ovary-intact female mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 314, Issue 2, 2018, Pages H330-H342

  Kim, Seong Chul ^a   Boese, Austin C ^a   Moore, Matthew H ^a   Cleland, Rea M ^a   Chang, Lin ^b   Delafontaine, Patrice ^a   Yin, Ke Jie ^c   Lee, Jean Pyo ^a   Hamblin, Milton H ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelial cells; Estrogen; Estrogen receptor ; Extracellular signal regulated kinase; Vascular function

Indexed keywords

1,3 BIS(4 HYDROXYPHENYL) 4 METHYL 5 [4 (2 PIPERIDINYLETHOXY) PHENOL] 1H PYRAZOLE DIHYDROCHLORIDE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4,4',4'' (4 PROPYL [1H]PYRAZOLE 1,3,5 TRIYL)TRIS PHENOL; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG; 4,4',4''-(4-PROPYL-((1)H)-PYRAZOLE-1,3,5-TRIYL) TRIS-PHENOL; PHENOL DERIVATIVE; PYRAZOLE DERIVATIVE; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; IMMUNOFLUORESCENCE; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE CELL; VASODILATATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; COMPARATIVE STUDY; DEFICIENCY; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; SEX FACTOR; SMOOTH MUSCLE CELL; THORACIC AORTA; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENOLS; PYRAZOLES; SEX FACTORS; SIGNAL TRANSDUCTION; VASODILATION; VASODILATOR AGENTS;

EID: 85043536297     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00841.2016     Document Type: Article

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