Nuclear import mechanism for myocardin family members and their correlation with vascular smooth muscle cell phenotype

Journal of Biological Chemistry

Volumn 285, Issue 48, 2010, Pages 37314-37323

  Nakamura, Seiji ^a,b   Hayashi, KeN'Ichiro ^a   Iwasaki, Kazuhiro ^a,c   Fujioka, Tomoaki ^c   Egusa, Hiroshi ^b   Yatani, Hirofumi ^b   Sobue, Kenji ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOWN-REGULATION; EXPRESSION LEVELS; HETERODIMERS; IMPORTINS; IN-VITRO ANALYSIS; MYOCARDIN; NUCLEAR IMPORT; NUCLEAR IMPORT MACHINERY; SERUM RESPONSE FACTORS; SMOOTH MUSCLE CELLS; VASCULAR SMOOTH MUSCLE CELLS;

BINDING ENERGY; CELLS; CYTOLOGY; MACHINERY; MUSCLE; TRANSCRIPTION FACTORS;

BLOOD VESSEL PROSTHESES;

G ACTIN; HETERODIMER; KARYOPHERIN ALPHA; KARYOPHERIN BETA; MYOCARDIN; MYOCARDIN RELATED TRANSCRIPTION FACTOR A; MYOCARDIN RELATED TRANSCRIPTION FACTOR B; NUCLEAR PROTEIN; PROTEIN SMC; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL CULTURE; CELL DEDIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE LOCATION; GENE REPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC CORRELATION; IN VITRO STUDY; MALE; NONHUMAN; NUCLEAR IMPORT; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; CELLS, CULTURED; KARYOPHERINS; MALE; MICE; MULTIGENE FAMILY; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 78549269804     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.180786     Document Type: Article

References (29)

1. Wang, D., Chang, P. S., Wang, Z., Sutherland, L., Richardson, J. A., Small, E., Krieg, P. A., and Olson, E. N. (2001) Cell 105, 851-862
2. Ma, Z., Morris, S. W., Valentine, V., Li, M., Herbrick, J. A., Cui, X., Bouman, D., Li, Y., Mehta, P. K., Nizetic, D., Kaneko, Y., Chan, G. C., Chan, L. C., Squire, J., Scherer, S. W., and Hitzler, J. K. (2001) Nat. Genet. 28, 220-221
3. Mercher, T., Coniat, M. B., Monni, R., Mauchauffe, M., Nguyen Khac, F., Gressin, L., Mugneret, F., Leblanc, T., Dastugue, N., Berger, R., and Bernard, O. A. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 5776-5779
4. Miralles, F., Posern, G., Zaromytidou, A. I., and Treisman, R. (2003) Cell 113, 329-342
5. Wang, D. Z., Li, S., Hockemeyer, D., Sutherland, L., Wang, Z., Schratt, G., Richardson, J. A., Nordheim, A., and Olson, E. N. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 14855-14860
6. Liu, N., and Olson, E. N. (2006) Curr. Opin. Cell Biol. 18, 715-722
7. Wang, Z., Wang, D. Z., Pipes, G. C., and Olson, E. N. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 7129-7134
8. Hayashi, K., Nakamura, S., Nishida, W., and Sobue, K. (2006) Mol. Cell. Biol. 26, 9456-9470
9. Wang, Z., Wang, D. Z., Hockemeyer, D., McAnally, J., Nordheim, A., and Olson, E. N. (2004) Nature 428, 185-189
10. Du, K. L., Chen, M., Li, J., Lepore, J. J., Mericko, P., and Parmacek, M. S. (2004) J. Biol. Chem. 279, 17578-17586
11. Hinson, J. S., Medlin, M. D., Lockman, K., Taylor, J. M., and Mack, C. P. (2007) Am. J. Physiol. Heart Circ. Physiol. 292, H1170-H1180
12. Guettler, S., Vartiainen, M. K., Miralles, F., Larijani, B., and Treisman, R. (2008) Mol. Cell. Biol. 28, 732-742
13. Posern, G., and Treisman, R. (2006) Trends Cell Biol. 16, 588-596
14. Vartiainen, M. K., Guettler, S., Larijani, B., and Treisman, R. (2007) Science 316, 1749-1752
15. Muehlich, S., Wang, R., Lee, S. M., Lewis, T. C., Dai, C., and Prywes, R. (2008) Mol. Cell. Biol. 28, 6302-6313
16. Hayashi, K., Saga, H., Chimori, Y., Kimura, K., Yamanaka, Y., and Sobue, K. (1998) J. Biol. Chem. 273, 28860-28867
17. Kimura, Y., Morita, T., Hayashi, K., Miki, T., and Sobue, K. (2010) Cancer Res. 70, 501-511
18. Morita, T., Mayanagi, T., and Sobue, K. (2007) Exp. Cell Res. 313, 3432-3445
19. Thierbach, G., Kalinowski, J., Bachmann, B., and Pühler, A. (1990) Appl. Microbiol. Biotechnol. 32, 443-448
20. Yoneda, Y. (1997) J. Biochem. 121, 811-817
21. Hayashi, K., Takahashi, M., Nishida, W., Yoshida, K., Ohkawa, Y., Kitabatake, A., Aoki, J., Arai, H., and Sobue, K. (2001) Circ. Res. 89, 251-258
22. Hayashi, K., Shibata, K., Morita, T., Iwasaki, K., Watanabe, M., and Sobue, K. (2004) J. Biol. Chem. 279, 40807-40818
23. Goldfarb, D. S., Corbett, A. H., Mason, D. A., Harreman, M. T., and Adam, S. A. (2004) Trends Cell Biol. 14, 505-514
24. Lange, A., Mills, R. E., Lange, C. J., Stewart, M., Devine, S. E., and Corbett, A. H. (2007) J. Biol. Chem. 282, 5101-5105
25. Moroianu, J., Hijikata, M., Blobel, G., and Radu, A. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 6532-6536
26. Hu, G., Wang, X., Saunders, D. N., Henderson, M., Russell, A. J., Herring, B. P., and Zhou, J. (2010) J. Biol. Chem. 285, 11800-11809
27. Xie, P., Fan, Y., Zhang, H., Zhang, Y., She, M., Gu, D., Patterson, C., and Li, H. (2009) Mol. Cell. Biol. 29, 2398-2408
28. Posern, G., Sotiropoulos, A., and Treisman, R. (2002) Mol. Biol. Cell. 13, 4167-4178
29. Yasuhara, N., Shibazaki, N., Tanaka, S., Nagai, M., Kamikawa, Y., Oe, S., Asally, M., Kamachi, Y., Kondoh, H., and Yoneda, Y. (2007) Nat. Cell Biol. 9, 72-79