Vitamin therapy in critically ill patients: focus on thiamine, vitamin C, and vitamin D

Intensive Care Medicine

Volumn 44, Issue 11, 2018, Pages 1940-1944

  Amrein, Karin ^a   Oudemans van Straaten, Heleen M ^b   Berger, Mette M ^c  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; THIAMINE; VITAMIN D; VITAMIN;

ACUTE DISEASE; ARTICLE; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; HUMAN; VITAMIN SUPPLEMENTATION;

ASCORBIC ACID; CRITICAL ILLNESS; HUMANS; THIAMINE; VITAMIN D; VITAMINS;

EID: 85043353954     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-018-5107-y     Document Type: Article

References (15)

1. Leite HP, de Lima LF (2016) Metabolic resuscitation in sepsis: a necessary step beyond the hemodynamic? J Thorac Dis 8:E552–E557
2. Mallat J, Lemyze M, Thevenin D (2016) Do not forget to give thiamine to your septic shock patient! J Thorac Dis 8:1062–1066
3. Luger M, Hiesmayr M, Koppel P, Sima B, Ranz I, Weiss C, Konig J, Luger E, Kruschitz R, Ludvik B, Schindler K (2015) Influence of intravenous thiamine supplementation on blood lactate concentration prior to cardiac surgery: a double-blinded, randomised controlled pilot study. Eur J Anaesthesiol 32:543–548
4. Donnino MW, Andersen LW, Chase M, Berg KM, Tidswell M, Giberson T, Wolfe R, Moskowitz A, Smithline H, Ngo L, Cocchi MN, Center for Resuscitation Science Research Group (2016) Randomized, double-blind, placebo-controlled trial of thiamine as a metabolic resuscitator in septic shock: a pilot study. Crit Care Med 44:360–367
5. Moskowitz A, Andersen LW, Cocchi MN, Karlsson M, Patel PV, Donnino MW (2017) Thiamine as a renal protective agent in septic shock. a secondary analysis of a randomized, double-blind. Placebo-controlled Trial. Ann Am Thorac Soc 14:737–741
6. Marik PE, Khangoora V, Rivera R, Hooper MH, Catravas J (2017) Hydrocortisone, vitamin C, and thiamine for the treatment of severe sepsis and septic shock: a retrospective before–after study. Chest 151:1229–1238
7. Padayatty SJ, Levine M (2016) Vitamin C: the known and the unknown and Goldilocks. Oral Dis 22:463–493
8. Oudemans-van Straaten HM, Spoelstra-de Man AM, de Waard MC (2014) Vitamin C revisited. Crit Care 18:460
9. Fowler AA, Syed AA 3rd, Knowlson S, Sculthorpe R, Farthing D, DeWilde C, Farthing CA, Larus TL, Martin E, Brophy DF, Gupta S, Nursing Medical Respiratory Intensive Care Unit, Fisher BJ, Natarajan R (2014) Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. J Transl Med 12:32
10. Zabet MH, Mohammadi M, Ramezani M, Khalili H (2016) Effect of high-dose Ascorbic acid on vasopressor’s requirement in septic shock. J Res Pharm Pract 5:94–100
11. Holick MF (2007) Vitamin D deficiency. N Engl J Med 357:266–281
12. Putzu A, Belletti A, Cassina T, Clivio S, Monti G, Zangrillo A, Landoni G (2017) Vitamin D and outcomes in adult critically ill patients. A systematic review and meta-analysis of randomized trials. J Crit Care 38:109–114
13. Lasky-Su J, Dahlin A, Litonjua AA, Rogers AJ, McGeachie MJ, Baron RM, Gazourian L, Barragan-Bradford D, Fredenburgh LE, Choi AMK, Mogensen KM, Quraishi SA, Amrein K, Christopher KB (2017) Metabolome alterations in severe critical illness and vitamin D status. Crit Care 21:193
14. Amrein K, Martucci G, McNally JD (2017) When not to use meta-analysis: analysing the meta-analyses on vitamin D in critical care. Clin Nutr 36(6):1729–1730
15. Amrein K, Schnedl C, Holl A, Riedl R, Christopher KB, Pachler C, Urbanic Purkart T, Waltensdorfer A, Munch A, Warnkross H, Stojakovic T, Bisping E, Toller W, Smolle KH, Berghold A, Pieber TR, Dobnig H (2014) Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial. JAMA 312:1520–1530