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Volumn 38, Issue , 2017, Pages 109-114

Vitamin D and outcomes in adult critically ill patients. A systematic review and meta-analysis of randomized trials

Author keywords

Critical care; Critical illness; Mortality; Survival; Vitamin D

Indexed keywords

PLACEBO; VITAMIN D;

EID: 85013629403     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2016.10.029     Document Type: Review
Times cited : (94)

References (62)
  • 1
    • 84941799468 scopus 로고    scopus 로고
    • Vitamin D: increasing supplement use in at-risk groups—guidance and guidelines
    • NICE []
    • [1] National Institute for Health and Care Excellence, Vitamin D: increasing supplement use in at-risk groups—guidance and guidelines. 2014, NICE [ https://www.nice.org.uk/guidance].
    • (2014)
    • National Institute for Health and Care Excellence1
  • 2
    • 80052525699 scopus 로고    scopus 로고
    • Dietary supplement use among U.S. adults has increased since NHANES III (1988-1994)
    • [2] Gahche, J., Bailey, R., Burt, V., Hughes, J., Yetley, E., Dwyer, J., et al. Dietary supplement use among U.S. adults has increased since NHANES III (1988-1994). NCHS Data Brief, 2011, 1–8.
    • (2011) NCHS Data Brief , pp. 1-8
    • Gahche, J.1    Bailey, R.2    Burt, V.3    Hughes, J.4    Yetley, E.5    Dwyer, J.6
  • 3
    • 84897071025 scopus 로고    scopus 로고
    • Vitamin D metabolism, mechanism of action, and clinical applications
    • [3] Bikle, D.D., Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol 21 (2014), 319–329, 10.1016/j.chembiol.2013.12.016.
    • (2014) Chem Biol , vol.21 , pp. 319-329
    • Bikle, D.D.1
  • 4
    • 78650980472 scopus 로고    scopus 로고
    • Vitamin D insufficiency
    • [4] Thacher, T.D., Clarke, B.L., Vitamin D insufficiency. Mayo Clin Proc 86 (2011), 50–60, 10.4065/mcp.2010.0567.
    • (2011) Mayo Clin Proc , vol.86 , pp. 50-60
    • Thacher, T.D.1    Clarke, B.L.2
  • 5
    • 84899726223 scopus 로고    scopus 로고
    • Vitamin D status and its association with season, hospital, and sepsis mortality in critical illness
    • [5] Amrein, K., Zajic, P., Schnedl, C., Waltensdorfer, A., Fruhwald, S., Holl, A., et al. Vitamin D status and its association with season, hospital, and sepsis mortality in critical illness. Crit Care, 18, 2014, R47, 10.1186/cc13790.
    • (2014) Crit Care , vol.18 , pp. R47
    • Amrein, K.1    Zajic, P.2    Schnedl, C.3    Waltensdorfer, A.4    Fruhwald, S.5    Holl, A.6
  • 6
    • 84873707627 scopus 로고    scopus 로고
    • Significant perturbation of vitamin D-parathyroid-calcium axis and adverse clinical outcomes in critically ill patients
    • [6] Nair, P., Lee, P., Reynolds, C., Nguyen, N.D., Myburgh, J., Eisman, J.A., et al. Significant perturbation of vitamin D-parathyroid-calcium axis and adverse clinical outcomes in critically ill patients. Intensive Care Med 39 (2013), 267–274, 10.1007/s00134-012-2713-y.
    • (2013) Intensive Care Med , vol.39 , pp. 267-274
    • Nair, P.1    Lee, P.2    Reynolds, C.3    Nguyen, N.D.4    Myburgh, J.5    Eisman, J.A.6
  • 7
    • 65449151275 scopus 로고    scopus 로고
    • Vitamin D deficiency in critically ill patients
    • [7] Lee, P., Eisman, J.A., Center, J.R., Vitamin D deficiency in critically ill patients. N Engl J Med 360 (2009), 1912–1914, 10.1056/NEJMc0809996.
    • (2009) N Engl J Med , vol.360 , pp. 1912-1914
    • Lee, P.1    Eisman, J.A.2    Center, J.R.3
  • 9
    • 84890142663 scopus 로고    scopus 로고
    • Vitamin D status and ill health: a systematic review
    • [9] Autier, P., Boniol, M., Pizot, C., Mullie, P., Vitamin D status and ill health: a systematic review. Lancet Diabetes Endocrinol 2 (2014), 76–89, 10.1016/S2213-8587(13)70165-7.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 76-89
    • Autier, P.1    Boniol, M.2    Pizot, C.3    Mullie, P.4
  • 10
    • 84927751246 scopus 로고    scopus 로고
    • Association between vitamin D deficiency and mortality in critically ill adult patients: a meta-analysis of cohort studies
    • [10] Zhang, Y.-P., Wan, Y.-D., Sun, T.-W., Kan, Q.-C., Wang, L.-X., Association between vitamin D deficiency and mortality in critically ill adult patients: a meta-analysis of cohort studies. Crit Care, 18, 2014, 684, 10.1186/s13054-014-0684-9.
    • (2014) Crit Care , vol.18 , pp. 684
    • Zhang, Y.-P.1    Wan, Y.-D.2    Sun, T.-W.3    Kan, Q.-C.4    Wang, L.-X.5
  • 11
    • 84906849213 scopus 로고    scopus 로고
    • Deficiency in 25-hydroxyvitamin D and 30-day mortality in patients with severe sepsis and septic shock
    • [11] Rech, M.A., Hunsaker, T., Rodriguez, J., Deficiency in 25-hydroxyvitamin D and 30-day mortality in patients with severe sepsis and septic shock. Am J Crit Care 23 (2014), e72–e79, 10.4037/ajcc2014723.
    • (2014) Am J Crit Care , vol.23 , pp. e72-e79
    • Rech, M.A.1    Hunsaker, T.2    Rodriguez, J.3
  • 12
    • 84878576971 scopus 로고    scopus 로고
    • Serum 1,25-dihydroxyvitamin D: an outcome prognosticator in human sepsis
    • [12] Nguyen, H.B., Eshete, B., Lau, K.H.W., Sai, A., Villarin, M., Baylink, D., Serum 1,25-dihydroxyvitamin D: an outcome prognosticator in human sepsis. PLoS One, 8, 2013, e64348, 10.1371/journal.pone.0064348.
    • (2013) PLoS One , vol.8 , pp. e64348
    • Nguyen, H.B.1    Eshete, B.2    Lau, K.H.W.3    Sai, A.4    Villarin, M.5    Baylink, D.6
  • 13
    • 83055187774 scopus 로고    scopus 로고
    • Vitamin D deficiency is associated with mortality in the medical intensive care unit
    • [13] Venkatram, S., Chilimuri, S., Adrish, M., Salako, A., Patel, M., Diaz-Fuentes, G., Vitamin D deficiency is associated with mortality in the medical intensive care unit. Crit Care, 15, 2011, R292, 10.1186/cc10585.
    • (2011) Crit Care , vol.15 , pp. R292
    • Venkatram, S.1    Chilimuri, S.2    Adrish, M.3    Salako, A.4    Patel, M.5    Diaz-Fuentes, G.6
  • 14
    • 84930649625 scopus 로고    scopus 로고
    • Significant association between vitamin D deficiency and sepsis: a systematic review and meta-analysis
    • [14] Upala, S., Sanguankeo, A., Permpalung, N., Significant association between vitamin D deficiency and sepsis: a systematic review and meta-analysis. BMC Anesthesiol, 15, 2015, 84, 10.1186/s12871-015-0063-3.
    • (2015) BMC Anesthesiol , vol.15 , pp. 84
    • Upala, S.1    Sanguankeo, A.2    Permpalung, N.3
  • 15
    • 84928587348 scopus 로고    scopus 로고
    • The relationship between immediate preoperative serum 25-hydroxy-vitamin D3 levels and cardiac function, dysglycemia, length of stay, and 30-d readmissions in cardiac surgery patients
    • [15] Sriram, K., Perumal, K., Alemzadeh, G., Osei, A., Voronov, G., The relationship between immediate preoperative serum 25-hydroxy-vitamin D3 levels and cardiac function, dysglycemia, length of stay, and 30-d readmissions in cardiac surgery patients. Nutrition 31 (2015), 820–826, 10.1016/j.nut.2014.11.022.
    • (2015) Nutrition , vol.31 , pp. 820-826
    • Sriram, K.1    Perumal, K.2    Alemzadeh, G.3    Osei, A.4    Voronov, G.5
  • 16
    • 79955765866 scopus 로고    scopus 로고
    • Institute of Medicine (US) committee to review dietary reference intakes for vitamin D and calcium
    • A.C. Ross
    • [16] Taylor, C.L., Yaktine, A.L., Del Valle, H.B., Institute of Medicine (US) committee to review dietary reference intakes for vitamin D and calcium. Ross, A.C., (eds.) Overview of vitamin D, 2011, 10.17226/13050.
    • (2011) Overview of vitamin D
    • Taylor, C.L.1    Yaktine, A.L.2    Del Valle, H.B.3
  • 17
    • 49249085519 scopus 로고    scopus 로고
    • Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women
    • [17] Peterson, C.A., Heffernan, M.E., Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women. J Inflamm (Lond), 5, 2008, 10, 10.1186/1476-9255-5-10.
    • (2008) J Inflamm (Lond) , vol.5 , pp. 10
    • Peterson, C.A.1    Heffernan, M.E.2
  • 18
    • 78649330206 scopus 로고    scopus 로고
    • Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients
    • [18] Krishnan, A., Ochola, J., Mundy, J., Jones, M., Kruger, P., Duncan, E., et al. Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients. Crit Care, 14, 2010, R216, 10.1186/cc9341.
    • (2010) Crit Care , vol.14 , pp. R216
    • Krishnan, A.1    Ochola, J.2    Mundy, J.3    Jones, M.4    Kruger, P.5    Duncan, E.6
  • 19
    • 80053646487 scopus 로고    scopus 로고
    • Variations in serum 25-hydroxyvitamin D during acute pancreatitis: an exploratory longitudinal study
    • [19] Bang, U.C., Novovic, S., Andersen, A.M., Fenger, M., Hansen, M.B., Jensen, J.-E.B., Variations in serum 25-hydroxyvitamin D during acute pancreatitis: an exploratory longitudinal study. Endocr Res 36 (2011), 135–141, 10.3109/07435800.2011.554937.
    • (2011) Endocr Res , vol.36 , pp. 135-141
    • Bang, U.C.1    Novovic, S.2    Andersen, A.M.3    Fenger, M.4    Hansen, M.B.5    Jensen, J.-E.B.6
  • 20
    • 84877914696 scopus 로고    scopus 로고
    • National growth in intensive care unit admissions from emergency departments in the United States from 2002 to 2009
    • [20] Mullins, P.M., Goyal, M., Pines, J.M., National growth in intensive care unit admissions from emergency departments in the United States from 2002 to 2009. Acad Emerg Med 20 (2013), 479–486, 10.1111/acem.12134.
    • (2013) Acad Emerg Med , vol.20 , pp. 479-486
    • Mullins, P.M.1    Goyal, M.2    Pines, J.M.3
  • 21
    • 84922677929 scopus 로고    scopus 로고
    • Vitamin D supplementation in the ICU patient
    • [21] Christopher, K.B., Vitamin D supplementation in the ICU patient. Curr Opin Clin Nutr Metab Care 18 (2015), 187–192, 10.1097/MCO.0000000000000147.
    • (2015) Curr Opin Clin Nutr Metab Care , vol.18 , pp. 187-192
    • Christopher, K.B.1
  • 22
    • 84908145123 scopus 로고    scopus 로고
    • Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial
    • [22] Amrein, K., Schnedl, C., Holl, A., Riedl, R., Christopher, K.B., Pachler, C., et al. Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial. JAMA 312 (2014), 1520–1530, 10.1001/jama.2014.13204.
    • (2014) JAMA , vol.312 , pp. 1520-1530
    • Amrein, K.1    Schnedl, C.2    Holl, A.3    Riedl, R.4    Christopher, K.B.5    Pachler, C.6
  • 23
    • 84891784332 scopus 로고    scopus 로고
    • Meta-analysis of long-term vitamin D supplementation on overall mortality
    • [23] Zheng, Y., Zhu, J., Zhou, M., Cui, L., Yao, W., Liu, Y., Meta-analysis of long-term vitamin D supplementation on overall mortality. PLoS One, 8, 2013, e82109, 10.1371/journal.pone.0082109.
    • (2013) PLoS One , vol.8 , pp. e82109
    • Zheng, Y.1    Zhu, J.2    Zhou, M.3    Cui, L.4    Yao, W.5    Liu, Y.6
  • 24
    • 84906938153 scopus 로고    scopus 로고
    • Vitamin D supplements and cancer incidence and mortality: a meta-analysis
    • [24] Keum, N., Giovannucci, E., Vitamin D supplements and cancer incidence and mortality: a meta-analysis. Br J Cancer 111 (2014), 976–980, 10.1038/bjc.2014.294.
    • (2014) Br J Cancer , vol.111 , pp. 976-980
    • Keum, N.1    Giovannucci, E.2
  • 26
    • 85100415918 scopus 로고    scopus 로고
    • Cochrane handbook for systematic reviews of interventions. Version 5
    • The Cochrane Collaboration
    • [26] Higgins, J.P., Green, S., Cochrane handbook for systematic reviews of interventions. Version 5. 2011, The Cochrane Collaboration.
    • (2011)
    • Higgins, J.P.1    Green, S.2
  • 27
    • 33846511123 scopus 로고    scopus 로고
    • Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data
    • [27] Friedrich, J.O., Adhikari, N.K.J., Beyene, J., Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data. BMC Med Res Methodol, 7, 2007, 5, 10.1186/1471-2288-7-5.
    • (2007) BMC Med Res Methodol , vol.7 , pp. 5
    • Friedrich, J.O.1    Adhikari, N.K.J.2    Beyene, J.3
  • 28
    • 68549101842 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration
    • [28] Liberati, A., Altman, D.G., Tetzlaff, J., Mulrow, C., Gøtzsche, P.C., Ioannidis, J.P.A., et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ, 339, 2009, b2700, 10.1136/bmj.b2700.
    • (2009) BMJ , vol.339 , pp. b2700
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3    Mulrow, C.4    Gøtzsche, P.C.5    Ioannidis, J.P.A.6
  • 29
    • 84888431150 scopus 로고    scopus 로고
    • Review Manager (RevMan) [computer program] version 5.3
    • The Nordic Cochrane Centre, The Cochrane Collaboration Copenhagen
    • [29] Review Manager (RevMan) [computer program] version 5.3. 2012, The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen.
    • (2012)
  • 30
    • 85019048607 scopus 로고    scopus 로고
    • Clinical trial of vitamin D2 vs D3 supplementation in critically ill pediatric burn patients
    • [30] Gottschlich, M.M., Mayes, T., Khoury, J., Kagan, R.J., Clinical trial of vitamin D2 vs D3 supplementation in critically ill pediatric burn patients. JPEN J Parenter Enteral Nutr, 2015, 10.1177/0148607115587948.
    • (2015) JPEN J Parenter Enteral Nutr
    • Gottschlich, M.M.1    Mayes, T.2    Khoury, J.3    Kagan, R.J.4
  • 31
    • 77956626575 scopus 로고    scopus 로고
    • Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial
    • [31] Manaseki-Holland, S., Qader, G., Isaq Masher, M., Bruce, J., Zulf Mughal, M., Chandramohan, D., et al. Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial. Trop Med Int Health 15 (2010), 1148–1155, 10.1111/j.1365-3156.2010.02578.x.
    • (2010) Trop Med Int Health , vol.15 , pp. 1148-1155
    • Manaseki-Holland, S.1    Qader, G.2    Isaq Masher, M.3    Bruce, J.4    Zulf Mughal, M.5    Chandramohan, D.6
  • 32
    • 84866053274 scopus 로고    scopus 로고
    • Vitamin D supplementation for severe pneumonia—a randomized controlled trial
    • [32] Choudhary, N., Gupta, P., Vitamin D supplementation for severe pneumonia—a randomized controlled trial. Indian Pediatr 49 (2012), 449–454, 10.1007/s13312-012-0073-x.
    • (2012) Indian Pediatr , vol.49 , pp. 449-454
    • Choudhary, N.1    Gupta, P.2
  • 33
    • 84946709004 scopus 로고    scopus 로고
    • Investigation of bone health subsequent to vitamin D supplementation in children following burn injury
    • [33] Mayes, T., Gottschlich, M.M., Khoury, J., Kagan, R.J., Investigation of bone health subsequent to vitamin D supplementation in children following burn injury. Nutr Clin Pract 30 (2015), 830–837, 10.1177/0884533615587720.
    • (2015) Nutr Clin Pract , vol.30 , pp. 830-837
    • Mayes, T.1    Gottschlich, M.M.2    Khoury, J.3    Kagan, R.J.4
  • 34
    • 84941116484 scopus 로고    scopus 로고
    • Response of vitamin D binding protein and free vitamin D concentrations to vitamin D supplementation in hospitalized premature infants
    • [34] Hanson, C., Lyden, E., Nelson, A., Thoene, M., Wagner, J., Wu, A., et al. Response of vitamin D binding protein and free vitamin D concentrations to vitamin D supplementation in hospitalized premature infants. J Pediatr Endocrinol Metab 28 (2015), 1107–1114, 10.1515/jpem-2015-0089.
    • (2015) J Pediatr Endocrinol Metab , vol.28 , pp. 1107-1114
    • Hanson, C.1    Lyden, E.2    Nelson, A.3    Thoene, M.4    Wagner, J.5    Wu, A.6
  • 35
    • 85026617895 scopus 로고    scopus 로고
    • Correction of vitamin D deficiency in critically ill patients: a randomized placebo-controlled trial
    • [35] Amrein, K., Schnedl, C., Holl, A., Riedl, R., Pachler, C., Pieber, T.R., et al. Correction of vitamin D deficiency in critically ill patients: a randomized placebo-controlled trial. Clin Nutr, 33, 2014, S13, 10.1016/S0261-5614(14)50030-1.
    • (2014) Clin Nutr , vol.33 , pp. S13
    • Amrein, K.1    Schnedl, C.2    Holl, A.3    Riedl, R.4    Pachler, C.5    Pieber, T.R.6
  • 36
    • 85013654764 scopus 로고    scopus 로고
    • Effect of cholecalciferol supplementation on vitamin D status and cathelicidin levels in sepsis
    • [Oral Abstract Session: Sepsis]
    • [36] Quraishi, S., DePascale, G., Needleman, J., Camargo, C.J., Ednan, B., Bhan, et al. Effect of cholecalciferol supplementation on vitamin D status and cathelicidin levels in sepsis. Crit Care Med, 42, 2014 [Oral Abstract Session: Sepsis].
    • (2014) Crit Care Med , vol.42
    • Quraishi, S.1    DePascale, G.2    Needleman, J.3    Camargo, C.J.4    Ednan, B.5    Bhan6
  • 37
    • 85026617938 scopus 로고    scopus 로고
    • Impact of vitamin D status and high-dose vitamin D3 administration on the plasma metabolome in critically ill adults
    • [37] Perry-Walker, K., Walker, D.I., Alvarez, J.A., Han, J.E., Jones, J.L., Hao, L., et al. Impact of vitamin D status and high-dose vitamin D3 administration on the plasma metabolome in critically ill adults. FASEB J, 30, 2016, 271.3.
    • (2016) FASEB J , vol.30 , pp. 271.3
    • Perry-Walker, K.1    Walker, D.I.2    Alvarez, J.A.3    Han, J.E.4    Jones, J.L.5    Hao, L.6
  • 38
    • 85026618672 scopus 로고    scopus 로고
    • Effect of high-dose vitamin D on antimicrobial peptides in ventilator-dependent critically ill patients
    • [38] Jones, J., Alvarez, J., Han, J., Hao, L., Chiang, E., Brown, L., et al. Effect of high-dose vitamin D on antimicrobial peptides in ventilator-dependent critically ill patients. FASEB J, 29, 2015, 920.3.
    • (2015) FASEB J , vol.29 , pp. 920.3
    • Jones, J.1    Alvarez, J.2    Han, J.3    Hao, L.4    Chiang, E.5    Brown, L.6
  • 40
    • 84942295190 scopus 로고    scopus 로고
    • Dose-response effect of ergocalciferol therapy on serum 25-hydroxyvitamin D concentration during critical illness
    • [40] Dickerson, R.N., Berry, S.C., Ziebarth, J.D., Swanson, J.M., Maish, G.O., Minard, G., et al. Dose-response effect of ergocalciferol therapy on serum 25-hydroxyvitamin D concentration during critical illness. Nutrition 31 (2015), 1219–1223, 10.1016/j.nut.2015.03.008.
    • (2015) Nutrition , vol.31 , pp. 1219-1223
    • Dickerson, R.N.1    Berry, S.C.2    Ziebarth, J.D.3    Swanson, J.M.4    Maish, G.O.5    Minard, G.6
  • 42
    • 77954762674 scopus 로고    scopus 로고
    • Evaluation of vitamin D endocrine system (VDES) status and response to treatment of patients in intensive care units (ICUs) using an on-line SPE-LC–MS/MS method
    • [42] Mata-Granados, J.M., Vargas-Vasserot, J., Ferreiro-Vera, C., Luque de Castro, M.D., Pavón, R.G., Quesada Gómez, J.M., Evaluation of vitamin D endocrine system (VDES) status and response to treatment of patients in intensive care units (ICUs) using an on-line SPE-LC–MS/MS method. J Steroid Biochem Mol Biol 121 (2010), 452–455, 10.1016/j.jsbmb.2010.03.078.
    • (2010) J Steroid Biochem Mol Biol , vol.121 , pp. 452-455
    • Mata-Granados, J.M.1    Vargas-Vasserot, J.2    Ferreiro-Vera, C.3    Luque de Castro, M.D.4    Pavón, R.G.5    Quesada Gómez, J.M.6
  • 43
    • 84924226217 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D3 treatment normalize the vitamin D status and the innate immune response mediated by cathelicidin in critically ill patients
    • [43] Vargas-Vasserot, J., Mata-Granados, J.M., Luque de Castro, M., Guerrero Pavón, R., Quesada Gomez, J., 25-hydroxyvitamin D3 treatment normalize the vitamin D status and the innate immune response mediated by cathelicidin in critically ill patients. Bone 48 (2011), S146–S147, 10.1016/j.bone.2011.03.310.
    • (2011) Bone , vol.48 , pp. S146-S147
    • Vargas-Vasserot, J.1    Mata-Granados, J.M.2    Luque de Castro, M.3    Guerrero Pavón, R.4    Quesada Gomez, J.5
  • 44
    • 84857049182 scopus 로고    scopus 로고
    • Effect of restoration of 25OHD3 status in prolonged critical illness on serum innate immunity parameters LL-37 and sCD163
    • [44] Ingels, C., Van Cromphaut, S., Wouters, P., Moller, H., Van Herck, E., Jans, I., et al. Effect of restoration of 25OHD3 status in prolonged critical illness on serum innate immunity parameters LL-37 and sCD163. Crit Care, 14, 2010, P590, 10.1186/cc8822.
    • (2010) Crit Care , vol.14 , pp. P590
    • Ingels, C.1    Van Cromphaut, S.2    Wouters, P.3    Moller, H.4    Van Herck, E.5    Jans, I.6
  • 45
    • 84944457785 scopus 로고    scopus 로고
    • A randomized study of a single dose of intramuscular cholecalciferol in critically ill adults
    • [45] Nair, P., Venkatesh, B., Lee, P., Kerr, S., Hoechter, D.J., Dimeski, G., et al. A randomized study of a single dose of intramuscular cholecalciferol in critically ill adults. Crit Care Med 43 (2015), 2313–2320, 10.1097/CCM.0000000000001201.
    • (2015) Crit Care Med , vol.43 , pp. 2313-2320
    • Nair, P.1    Venkatesh, B.2    Lee, P.3    Kerr, S.4    Hoechter, D.J.5    Dimeski, G.6
  • 47
    • 84942117832 scopus 로고    scopus 로고
    • Effect of cholecalciferol supplementation on vitamin D status and cathelicidin levels in sepsis: a randomized, placebo-controlled trial
    • [47] Quraishi, S.A., De Pascale, G., Needleman, J.S., Nakazawa, H., Kaneki, M., Bajwa, E.K., et al. Effect of cholecalciferol supplementation on vitamin D status and cathelicidin levels in sepsis: a randomized, placebo-controlled trial. Crit Care Med 43 (2015), 1928–1937, 10.1097/CCM.0000000000001148.
    • (2015) Crit Care Med , vol.43 , pp. 1928-1937
    • Quraishi, S.A.1    De Pascale, G.2    Needleman, J.S.3    Nakazawa, H.4    Kaneki, M.5    Bajwa, E.K.6
  • 48
    • 79953109768 scopus 로고    scopus 로고
    • Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study
    • [48] Amrein, K., Sourij, H., Wagner, G., Holl, A., Pieber, T.R., Smolle, K.H., et al. Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study. Crit Care, 15, 2011, R104, 10.1186/cc10120.
    • (2011) Crit Care , vol.15 , pp. R104
    • Amrein, K.1    Sourij, H.2    Wagner, G.3    Holl, A.4    Pieber, T.R.5    Smolle, K.H.6
  • 49
    • 84865172895 scopus 로고    scopus 로고
    • Pilot study of vitamin D supplementation in adults with cystic fibrosis pulmonary exacerbation: a randomized, controlled trial
    • [49] Grossmann, R.E., Zughaier, S.M., Kumari, M., Seydafkan, S., Lyles, R.H., Liu, S., et al. Pilot study of vitamin D supplementation in adults with cystic fibrosis pulmonary exacerbation: a randomized, controlled trial. Dermatoendocrinol 4 (2012), 191–197, 10.4161/derm.20332.
    • (2012) Dermatoendocrinol , vol.4 , pp. 191-197
    • Grossmann, R.E.1    Zughaier, S.M.2    Kumari, M.3    Seydafkan, S.4    Lyles, R.H.5    Liu, S.6
  • 50
    • 84963945601 scopus 로고    scopus 로고
    • Effect of vitamin D on stress-induced hyperglycaemia and insulin resistance in critically ill patients
    • [50] Alizadeh, N., Khalili, H., Mohammadi, M., Abdollahi, A., Ala, S., Effect of vitamin D on stress-induced hyperglycaemia and insulin resistance in critically ill patients. Int J Clin Pract, 2016, 10.1111/ijcp.12795.
    • (2016) Int J Clin Pract
    • Alizadeh, N.1    Khalili, H.2    Mohammadi, M.3    Abdollahi, A.4    Ala, S.5
  • 51
    • 84969749461 scopus 로고    scopus 로고
    • High dose vitamin D administration in ventilated intensive care unit patients: a pilot double blind randomized controlled trial
    • [51] Han, J.E., Jones, J.L., Tangpricha, V., Brown, M.A., Hao, L., Hebbar, G., et al. High dose vitamin D administration in ventilated intensive care unit patients: a pilot double blind randomized controlled trial. J Clin Transl Endocrinol 4 (2016), 59–65, 10.1016/j.jcte.2016.04.004.
    • (2016) J Clin Transl Endocrinol , vol.4 , pp. 59-65
    • Han, J.E.1    Jones, J.L.2    Tangpricha, V.3    Brown, M.A.4    Hao, L.5    Hebbar, G.6
  • 52
    • 84858150326 scopus 로고    scopus 로고
    • Vitamin D metabolism and signaling in the immune system
    • [52] White, J.H., Vitamin D metabolism and signaling in the immune system. Rev Endocr Metab Disord 13 (2012), 21–29, 10.1007/s11154-011-9195-z.
    • (2012) Rev Endocr Metab Disord , vol.13 , pp. 21-29
    • White, J.H.1
  • 53
    • 84862339087 scopus 로고    scopus 로고
    • Vitamin D receptor upregulation in alloreactive human T cells
    • [53] Joseph, R.W., Bayraktar, U.D., Kim, T.K., St John, L.S., Popat, U., Khalili, J., et al. Vitamin D receptor upregulation in alloreactive human T cells. Hum Immunol 73 (2012), 693–698, 10.1016/j.humimm.2012.04.019.
    • (2012) Hum Immunol , vol.73 , pp. 693-698
    • Joseph, R.W.1    Bayraktar, U.D.2    Kim, T.K.3    St John, L.S.4    Popat, U.5    Khalili, J.6
  • 54
    • 0021745894 scopus 로고
    • Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues
    • [54] Koeffler, H.P., Amatruda, T., Ikekawa, N., Kobayashi, Y., DeLuca, H.F., Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues. Cancer Res 44 (1984), 5624–5628.
    • (1984) Cancer Res , vol.44 , pp. 5624-5628
    • Koeffler, H.P.1    Amatruda, T.2    Ikekawa, N.3    Kobayashi, Y.4    DeLuca, H.F.5
  • 55
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • [55] Liu, P.T., Stenger, S., Li, H., Wenzel, L., Tan, B.H., Krutzik, S.R., et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311 (2006), 1770–1773, 10.1126/science.1123933.
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3    Wenzel, L.4    Tan, B.H.5    Krutzik, S.R.6
  • 57
    • 84901480732 scopus 로고    scopus 로고
    • Prospective study of vitamin D status at initiation of care in critically ill surgical patients and risk of 90-day mortality
    • [57] Quraishi, S.A., Bittner, E.A., Blum, L., McCarthy, C.M., Bhan, I., Camargo, C.A., Prospective study of vitamin D status at initiation of care in critically ill surgical patients and risk of 90-day mortality. Crit Care Med 42 (2014), 1365–1371, 10.1097/CCM.0000000000000210.
    • (2014) Crit Care Med , vol.42 , pp. 1365-1371
    • Quraishi, S.A.1    Bittner, E.A.2    Blum, L.3    McCarthy, C.M.4    Bhan, I.5    Camargo, C.A.6
  • 58
    • 84902578366 scopus 로고    scopus 로고
    • Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States
    • [58] Schöttker, B., Jorde, R., Peasey, A., Thorand, B., Jansen, E.H.J.M., de Groot, L., et al. Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States. BMJ, 348, 2014, g3656, 10.1136/bmj.g3656.
    • (2014) BMJ , vol.348 , pp. g3656
    • Schöttker, B.1    Jorde, R.2    Peasey, A.3    Thorand, B.4    Jansen, E.H.J.M.5    de Groot, L.6
  • 59
    • 84861580335 scopus 로고    scopus 로고
    • Vitamin D safety and requirements
    • [59] de Paula, F.J.A., Rosen, C.J., Vitamin D safety and requirements. Arch Biochem Biophys 523 (2012), 64–72, 10.1016/j.abb.2011.12.002.
    • (2012) Arch Biochem Biophys , vol.523 , pp. 64-72
    • de Paula, F.J.A.1    Rosen, C.J.2
  • 61
    • 0031003587 scopus 로고    scopus 로고
    • Summary of round table conference: gut dysfunction in critical illness
    • [61] Rombeau, J.L., Takala, J., Summary of round table conference: gut dysfunction in critical illness. Intensive Care Med 23 (1997), 476–479, 10.1007/s001340050361.
    • (1997) Intensive Care Med , vol.23 , pp. 476-479
    • Rombeau, J.L.1    Takala, J.2
  • 62
    • 0030470463 scopus 로고    scopus 로고
    • Impaired gastric emptying in mechanically ventilated, critically ill patients
    • [62] Heyland, D.K., Tougas, G., King, D., Cook, D.J., Impaired gastric emptying in mechanically ventilated, critically ill patients. Intensive Care Med 22 (1996), 1339–1344, 10.1007/BF01709548.
    • (1996) Intensive Care Med , vol.22 , pp. 1339-1344
    • Heyland, D.K.1    Tougas, G.2    King, D.3    Cook, D.J.4


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