Dietary fiber pectin directly blocks toll-like receptor 2-1 and prevents doxorubicin-induced ileitis

Frontiers in Immunology

Volumn 9, Issue MAR, 2018, Pages

  Sahasrabudhe, Neha M ^a   Beukema, Martin ^a   Tian, Lingmin ^b   Troost, Berit ^a   Scholte, Jan ^c   Bruininx, Erik ^b,d   Bruggeman, Geert ^e   van den Berg, Marco ^f   Scheurink, Anton ^c   Schols, Henk A ^b   Faas, Marijke M ^a   de Vos, Paul ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c Groningen Institute for Evolutionary Life Sciences   (Netherlands)

^d Agrifirm Innovation Center   (Netherlands)

^e Nuscience Group Headquarters   (Belgium)

^f DSM BIOTECHNOLOGY CENTER   (Netherlands)

Author keywords

Degree of methyl esterification; Dietary fiber; Ileitis; Pectin; Toll like receptor 2

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CXCL1 CHEMOKINE; DOXORUBICIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LACTIC ACID; MONOCYTE CHEMOTACTIC PROTEIN 1; PECTIN; PROPIONIC ACID; SHORT CHAIN FATTY ACID; SUCCINIC ACID; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR; VALERIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DIETARY FIBER; DRUG INDUCED DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ILEITIS; IMMUNOFLUORESCENCE; INNATE IMMUNITY; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PERITONEUM LAVAGE; PLASMID; POLYMERASE CHAIN REACTION; RAW 264.7 CELL LINE; SIZE EXCLUSION CHROMATOGRAPHY;

EID: 85042708682     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2018.00383     Document Type: Article

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