DPP-4 inhibitors improve diabetic wound healing via direct and indirect promotion of epithelial-mesenchymal transition and reduction of scarring

Diabetes

Volumn 67, Issue 3, 2018, Pages 518-531

  Long, Min ^a   Cai, Leiqin ^a   Li, Wenjie ^a   Zhang, Linlin ^a   Guo, Shaodong ^b   Zhang, Rui ^a   Zheng, Yi ^a   Liu, Xiufei ^a   Wang, Min ^a   Zhou, Xianli ^a   Wang, Hui ^a   Li, Xing ^a   Li, Ling ^c   Zhu, Zhiming ^d   Yang, Gangyi ^c   Zheng, Hongting ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b TEXAS A AND M UNIVERSITY   (United States)

^c CHONGQING MEDICAL UNIVERSITY   (China)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; STROMAL CELL DERIVED FACTOR 1ALPHA; TRANSCRIPTION FACTOR NRF2; UVOMORULIN; VIMENTIN;

ADULT; AGED; AMPUTATION; ANIMAL CELL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BODY MASS; BREAST FEEDING; CELL GROWTH; CELL PROLIFERATION ASSAY; COLLAGEN SYNTHESIS; DIABETES MELLITUS; DIABETIC PATIENT; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; FIBROBLAST; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KERATINOCYTE; KERATINOCYTE CELL LINE; LOWER LIMB; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; SCAR FORMATION; SKIN INJURY; STAINING; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ULCER; VERY ELDERLY; WESTERN BLOTTING; WOUND CLOSURE; WOUND HEALING; WOUND HEALING ASSAY; WOUND TISSUE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CELL MOTION; COMPLICATION; CONTROLLED STUDY; CYTOLOGY; DIABETIC FOOT; DRUG EFFECT; FOLLOW UP; HYPERGLYCEMIA; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SCAR; SEVERITY OF ILLNESS INDEX;

AGED; AGED, 80 AND OVER; ANIMALS; CELL LINE; CELL MOVEMENT; CELLS, CULTURED; CICATRIX; DIABETES MELLITUS, TYPE 2; DIABETIC FOOT; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERGLYCEMIA; KERATINOCYTES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; WOUND HEALING;

EID: 85042598288     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db17-0934     Document Type: Article

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