Age-Associated Increase in Skin Fibroblast-Derived Prostaglandin E2Contributes to Reduced Collagen Levels in Elderly Human Skin

Journal of Investigative Dermatology

Volumn 135, Issue 9, 2015, Pages 2181-2188

  Li, Yong ^a   Lei, Dan ^a   Swindell, William R ^a   Xia, Wei ^a   Weng, Shinuo ^b   Fu, Jianping ^b   Worthen, Christal A ^a   Okubo, Toru ^a   Johnston, Andrew ^a   Gudjonsson, Johann E ^a   Voorhees, John J ^a   Fisher, Gary J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; COLLAGEN; CYCLOOXYGENASE 2; DICLOFENAC; MESSENGER RNA; PROCOLLAGEN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; BIOLOGICAL MARKER;

ADULT; AGED; AGING; ARTICLE; BUTTOCK; COLLAGEN SYNTHESIS; CUTANEOUS PARAMETERS; ENZYME IMMUNOASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCH BIOPSY; SKIN BIOPSY; SKIN CULTURE; SKIN FIBROBLAST; AGE; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; SKIN; VERY ELDERLY; WESTERN BLOTTING; YOUNG ADULT;

ADULT; AGE FACTORS; AGED, 80 AND OVER; BIOMARKERS; BLOTTING, WESTERN; CELLS, CULTURED; COLLAGEN; DINOPROSTONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; SKIN; SKIN AGING; YOUNG ADULT;

EID: 84939467387     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.157     Document Type: Article

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