The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy

Kidney International

Volumn 89, Issue 5, 2016, Pages 1049-1061

  Tsuprykov, Oleg ^a,b   Ando, Ryotaro ^c   Reichetzeder, Christoph ^a,b   Von Websky, Karoline ^a,b   Antonenko, Viktoriia ^a,b   Sharkovska, Yuliya ^b   Chaykovska, Lyubov ^d   Rahnenführer, Jan ^a,b   Hasan, Ahmed A ^a   Tammen, Harald ^e   Alter, Markus ^b   Klein, Thomas ^f   Ueda, Seiji ^c   Yamagishi, Sho Ichi ^c   Okuda, Seiya ^c   Hocher, Berthold ^a,g,h  

^a UNIVERSITY OF POTSDAM   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^e PXBioVisioN GmbH   (Germany)

^f BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^g Institute of Comparative Infectiology and Zoonoses   (Germany)

^h HUNAN NORMAL UNIVERSITY   (China)

Author keywords

albuminuria; angiotensin receptor blockers; chronic kidney disease; DPP 4 inhibition; proteinuria; proteomic analysis

Indexed keywords

ALBUMIN; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; APOLIPOPROTEIN C1; ATRIAL NATRIURETIC FACTOR; BETA 2 MICROGLOBULIN; CD68 ANTIGEN; COLLAGEN TYPE 1; COLONY STIMULATING FACTOR 1; CREATININE; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN B1; LINAGLIPTIN; MALONALDEHYDE; OSTEOPONTIN; PLACEBO; STROMAL CELL DERIVED FACTOR 1ALPHA; TELMISARTAN; UNCLASSIFIED DRUG; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; BIOLOGICAL MARKER; DPP4 PROTEIN, RAT;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DRUG EFFICACY; KIDNEY FIBROSIS; KIDNEY MASS; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEINURIA; RAT; UPREGULATION; ANIMAL; BLOOD; BLOOD PRESSURE; DEFICIENCY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; FIBROSIS; FISCHER 344 RAT; GENETICS; KIDNEY; METABOLISM; PATHOLOGY; PROCEDURES; RENAL INSUFFICIENCY, CHRONIC; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TIME FACTOR; TRANSGENIC RAT;

ALBUMINURIA; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; BENZOATES; BIOMARKERS; BLOOD PRESSURE; CHROMATOGRAPHY, LIQUID; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FIBROSIS; KIDNEY; LINAGLIPTIN; MALE; MASS SPECTROMETRY; NEPHRECTOMY; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RENAL INSUFFICIENCY, CHRONIC; RENIN-ANGIOTENSIN SYSTEM; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84964689544     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2016.01.016     Document Type: Article

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