-
1
-
-
84884994218
-
The Cancer Genome Atlas Pan-Cancer analysis project
-
Weinstein JN, Collisson EA, Mills GB, et al. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet 2013; 45: 1113–1120.
-
(2013)
Nat Genet
, vol.45
, pp. 1113-1120
-
-
Weinstein, J.N.1
Collisson, E.A.2
Mills, G.B.3
-
2
-
-
84943613527
-
Comprehensive molecular portraits of invasive lobular breast cancer
-
Ciriello G, Gatza ML, Beck AH, et al. Comprehensive molecular portraits of invasive lobular breast cancer. Cell 2015; 163: 506–519.
-
(2015)
Cell
, vol.163
, pp. 506-519
-
-
Ciriello, G.1
Gatza, M.L.2
Beck, A.H.3
-
3
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490: 61–70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
4
-
-
84908460595
-
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
-
Hoadley KA, Yau C, Wolf DM, et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell 2014; 158: 929–944.
-
(2014)
Cell
, vol.158
, pp. 929-944
-
-
Hoadley, K.A.1
Yau, C.2
Wolf, D.M.3
-
5
-
-
84884997982
-
Emerging landscape of oncogenic signatures across human cancers
-
Ciriello G, Miller ML, Aksoy BA, et al. Emerging landscape of oncogenic signatures across human cancers. Nat Genet 2013; 45: 1127–1133.
-
(2013)
Nat Genet
, vol.45
, pp. 1127-1133
-
-
Ciriello, G.1
Miller, M.L.2
Aksoy, B.A.3
-
6
-
-
85015101723
-
Integrated molecular characterization of uterine carcinosarcoma
-
Cherniack AD, Shen H, Walter V, et al. Integrated molecular characterization of uterine carcinosarcoma. Cancer Cell 2017; 31: 411–423.
-
(2017)
Cancer Cell
, vol.31
, pp. 411-423
-
-
Cherniack, A.D.1
Shen, H.2
Walter, V.3
-
7
-
-
85032697928
-
Comprehensive and integrated genomic characterization of adult soft tissue sarcoma
-
The Cancer Genome Atlas Network. Comprehensive and integrated genomic characterization of adult soft tissue sarcoma. Cell 2017; 171: 950–965.
-
(2017)
Cell
, vol.171
, pp. 950-965
-
-
-
8
-
-
84885008220
-
Pan-cancer patterns of somatic copy number alteration
-
Zack TI, Schumacher SE, Carter SL, et al. Pan-cancer patterns of somatic copy number alteration. Nat Genet 2013; 45: 1134–1140.
-
(2013)
Nat Genet
, vol.45
, pp. 1134-1140
-
-
Zack, T.I.1
Schumacher, S.E.2
Carter, S.L.3
-
9
-
-
85017181661
-
Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities
-
St Pierre R, Kadoch C. Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities. Curr Opin Genet Dev 2017; 42: 56–67.
-
(2017)
Curr Opin Genet Dev
, vol.42
, pp. 56-67
-
-
St Pierre, R.1
Kadoch, C.2
-
10
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
The Cancer Genome Atlas Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014; 507: 315–322.
-
(2014)
Nature
, vol.507
, pp. 315-322
-
-
-
11
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012; 487: 330–337.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
12
-
-
0035132202
-
Histopathological identification of colon cancer with microsatellite instability
-
Alexander J, Watanabe T, Wu TT, et al. Histopathological identification of colon cancer with microsatellite instability. Am J Pathol 2001; 158: 527–535.
-
(2001)
Am J Pathol
, vol.158
, pp. 527-535
-
-
Alexander, J.1
Watanabe, T.2
Wu, T.T.3
-
13
-
-
85006307167
-
Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications
-
Shia J, Schultz N, Kuk D, et al. Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications. Mod Pathol 2017; 30: 599–609.
-
(2017)
Mod Pathol
, vol.30
, pp. 599-609
-
-
Shia, J.1
Schultz, N.2
Kuk, D.3
-
14
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417: 949–954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
15
-
-
0037112438
-
Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia
-
Yuen ST, Davies H, Chan TL, et al. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. Cancer Res 2002; 62: 6451–6455.
-
(2002)
Cancer Res
, vol.62
, pp. 6451-6455
-
-
Yuen, S.T.1
Davies, H.2
Chan, T.L.3
-
16
-
-
0037379904
-
High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
-
Kimura ET, Nikiforova MN, Zhu Z, et al. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res 2003; 63: 1454–1457.
-
(2003)
Cancer Res
, vol.63
, pp. 1454-1457
-
-
Kimura, E.T.1
Nikiforova, M.N.2
Zhu, Z.3
-
17
-
-
85026888109
-
Integrated genomic characterization of pancreatic ductal adenocarcinoma
-
The Cancer Genome Atlas Network. Integrated genomic characterization of pancreatic ductal adenocarcinoma. Cancer Cell 2017; 32: 185–203.
-
(2017)
Cancer Cell
, vol.32
, pp. 185-203
-
-
-
18
-
-
85030529396
-
Vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma: final overall survival results of the randomized BRIM-3 study
-
Chapman PB, Robert C, Larkin J, et al. Vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma: final overall survival results of the randomized BRIM-3 study. Ann Oncol 2017; 28: 2581–2587.
-
(2017)
Ann Oncol
, vol.28
, pp. 2581-2587
-
-
Chapman, P.B.1
Robert, C.2
Larkin, J.3
-
19
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364: 2507–2516.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
20
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
Flaherty KT, Infante JR, Daud A, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 2012; 367: 1694–1703.
-
(2012)
N Engl J Med
, vol.367
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
-
21
-
-
85038235280
-
Long-term outcomes in patients with BRAF V600-mutant metastatic melanoma who received dabrafenib combined with trametinib
-
Long GV, Eroglu Z, Infante J, et al. Long-term outcomes in patients with BRAF V600-mutant metastatic melanoma who received dabrafenib combined with trametinib. J Clin Oncol 2017.
-
(2017)
J Clin Oncol
-
-
Long, G.V.1
Eroglu, Z.2
Infante, J.3
-
22
-
-
84994525204
-
Vemurafenib in patients with BRAF(V600E)-positive metastatic or unresectable papillary thyroid cancer refractory to radioactive iodine: a non-randomised, multicentre, open-label, phase 2 trial
-
Brose MS, Cabanillas ME, Cohen EE, et al. Vemurafenib in patients with BRAF(V600E)-positive metastatic or unresectable papillary thyroid cancer refractory to radioactive iodine: a non-randomised, multicentre, open-label, phase 2 trial. Lancet Oncol 2016; 17: 1272–1282.
-
(2016)
Lancet Oncol
, vol.17
, pp. 1272-1282
-
-
Brose, M.S.1
Cabanillas, M.E.2
Cohen, E.E.3
-
23
-
-
84995752465
-
BRAF mutant colorectal cancer as a distinct subset of colorectal cancer: clinical characteristics, clinical behavior, and response to targeted therapies
-
Clarke CN, Kopetz ES. BRAF mutant colorectal cancer as a distinct subset of colorectal cancer: clinical characteristics, clinical behavior, and response to targeted therapies. J Gastrointest Oncol 2015; 6: 660–667.
-
(2015)
J Gastrointest Oncol
, vol.6
, pp. 660-667
-
-
Clarke, C.N.1
Kopetz, E.S.2
-
24
-
-
78649723255
-
LX4032 in metastatic colorectal cancer patients with mutant BRAF tumors
-
Kopetz S, Desai J, Chan E, et al. LX4032 in metastatic colorectal cancer patients with mutant BRAF tumors. ASCO Meeting Abstracts 2010; 28: 3534.
-
(2010)
ASCO Meeting Abstracts
, vol.28
, pp. 3534
-
-
Kopetz, S.1
Desai, J.2
Chan, E.3
-
25
-
-
84863230465
-
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
-
Prahallad A, Sun C, Huang S, et al. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 2012; 483: 100–103.
-
(2012)
Nature
, vol.483
, pp. 100-103
-
-
Prahallad, A.1
Sun, C.2
Huang, S.3
-
26
-
-
84933040790
-
Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations
-
Ahronian LG, Sennott EM, Van Allen EM, et al. Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations. Cancer Discov 2015; 5: 358–367.
-
(2015)
Cancer Discov
, vol.5
, pp. 358-367
-
-
Ahronian, L.G.1
Sennott, E.M.2
Van Allen, E.M.3
-
27
-
-
84861863158
-
EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib
-
Corcoran RB, Ebi H, Turke AB, et al. EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib. Cancer Discov 2012; 2: 227–235.
-
(2012)
Cancer Discov
, vol.2
, pp. 227-235
-
-
Corcoran, R.B.1
Ebi, H.2
Turke, A.B.3
-
28
-
-
84886047746
-
The evolution of melanoma resistance reveals therapeutic opportunities
-
Das Thakur M, Stuart DD. The evolution of melanoma resistance reveals therapeutic opportunities. Cancer Res 2013; 73: 6106–6110.
-
(2013)
Cancer Res
, vol.73
, pp. 6106-6110
-
-
Das Thakur, M.1
Stuart, D.D.2
-
29
-
-
84935009372
-
Genomic classification of cutaneous melanoma
-
The Cancer Genome Atlas Network. Genomic classification of cutaneous melanoma. Cell 2015; 161: 1681–1696.
-
(2015)
Cell
, vol.161
, pp. 1681-1696
-
-
-
30
-
-
85026887361
-
Integrative analysis identifies four molecular and clinical subsets in uveal melanoma
-
Robertson AG, Shih J, Yau C, et al. Integrative analysis identifies four molecular and clinical subsets in uveal melanoma. Cancer Cell 2017; 32: 204–220.
-
(2017)
Cancer Cell
, vol.32
, pp. 204-220
-
-
Robertson, A.G.1
Shih, J.2
Yau, C.3
-
31
-
-
84897509705
-
Screening for cervical cancer using automated analysis of PAP-smears
-
842037
-
Bengtsson E, Malm P. Screening for cervical cancer using automated analysis of PAP-smears. Comput Math Methods Med 2014; 2014: 842037.
-
(2014)
Comput Math Methods Med
, vol.2014
-
-
Bengtsson, E.1
Malm, P.2
-
32
-
-
85016456935
-
Whole slide imaging for analytical anatomic pathology and telepathology: practical applications today, promises, and perils
-
Farris AB, Cohen C, Rogers TE, et al. Whole slide imaging for analytical anatomic pathology and telepathology: practical applications today, promises, and perils. Arch Pathol Lab Med 2017; 141: 542–550.
-
(2017)
Arch Pathol Lab Med
, vol.141
, pp. 542-550
-
-
Farris, A.B.1
Cohen, C.2
Rogers, T.E.3
-
35
-
-
85044182630
-
-
[Accessed 31 October 2017]. Available from
-
Administration UFaD. Susbstantial Equivalence Determination 510K K071128. [Accessed 31 October 2017]. Available from: https://www.accessdata.fda.gov/cdrh_docs/reviews/K071128.pdf
-
Susbstantial Equivalence Determination 510K K071128
-
-
-
36
-
-
84922667184
-
Implementation of large-scale routine diagnostics using whole slide imaging in Sweden: digital pathology experiences 2006–2013
-
Thorstenson S, Molin J, Lundstrom C. Implementation of large-scale routine diagnostics using whole slide imaging in Sweden: digital pathology experiences 2006–2013. J Pathol Inform 2014; 5: 14.
-
(2014)
J Pathol Inform
, vol.5
, pp. 14
-
-
Thorstenson, S.1
Molin, J.2
Lundstrom, C.3
-
37
-
-
84896030153
-
Going fully digital: perspective of a Dutch academic pathology lab
-
Stathonikos N, Veta M, Huisman A, et al. Going fully digital: perspective of a Dutch academic pathology lab. J Pathol Inform 2013; 4: 15.
-
(2013)
J Pathol Inform
, vol.4
, pp. 15
-
-
Stathonikos, N.1
Veta, M.2
Huisman, A.3
-
38
-
-
56149094051
-
Computerized pathological image analysis for neuroblastoma prognosis
-
Gurcan MN, Kong J, Sertel O, et al. Computerized pathological image analysis for neuroblastoma prognosis. AMIA Annu Symp Proc 2007; 304–308.
-
(2007)
AMIA Annu Symp Proc
, pp. 304-308
-
-
Gurcan, M.N.1
Kong, J.2
Sertel, O.3
-
39
-
-
84952322940
-
Classification of follicular lymphoma: the effect of computer aid on pathologists grading
-
Fauzi MF, Pennell M, Sahiner B, et al. Classification of follicular lymphoma: the effect of computer aid on pathologists grading. BMC Med Inform Decis Mak 2015; 15: 115.
-
(2015)
BMC Med Inform Decis Mak
, vol.15
, pp. 115
-
-
Fauzi, M.F.1
Pennell, M.2
Sahiner, B.3
-
40
-
-
84885381855
-
Statistical shape model for manifold regularization: Gleason grading of prostate histology
-
Sparks R, Madabhushi A. Statistical shape model for manifold regularization: Gleason grading of prostate histology. Comput Vis Image Underst 2013; 117: 1138–1146.
-
(2013)
Comput Vis Image Underst
, vol.117
, pp. 1138-1146
-
-
Sparks, R.1
Madabhushi, A.2
-
41
-
-
82255185810
-
Adaptive energy selective active contour with shape priors for nuclear segmentation and Gleason grading of prostate cancer
-
Ali S, Veltri R, Epstein JI, et al. Adaptive energy selective active contour with shape priors for nuclear segmentation and Gleason grading of prostate cancer. Med Image Comput Comput Assist Interv 2011; 14: 661–669.
-
(2011)
Med Image Comput Comput Assist Interv
, vol.14
, pp. 661-669
-
-
Ali, S.1
Veltri, R.2
Epstein, J.I.3
-
42
-
-
81055146760
-
Systematic analysis of breast cancer morphology uncovers stromal features associated with survival
-
108ra113
-
Beck AH, Sangoi AR, Leung S, et al. Systematic analysis of breast cancer morphology uncovers stromal features associated with survival. Sci Transl Med 2011; 3: 108ra113.
-
(2011)
Sci Transl Med
, vol.3
-
-
Beck, A.H.1
Sangoi, A.R.2
Leung, S.3
-
43
-
-
84886280529
-
Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data
-
Gutman DA, Cobb J, Somanna D, et al. Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data. J Am Med Inform Assoc 2013; 20: 1091–1098.
-
(2013)
J Am Med Inform Assoc
, vol.20
, pp. 1091-1098
-
-
Gutman, D.A.1
Cobb, J.2
Somanna, D.3
-
44
-
-
63349101152
-
Core classification of lung cancer: correlating nuclear size and mitoses with ploidy and clinicopathological parameters
-
Petersen I, Kotb WF, Friedrich KH, et al. Core classification of lung cancer: correlating nuclear size and mitoses with ploidy and clinicopathological parameters. Lung Cancer 2009; 65: 312–318.
-
(2009)
Lung Cancer
, vol.65
, pp. 312-318
-
-
Petersen, I.1
Kotb, W.F.2
Friedrich, K.H.3
-
45
-
-
15244356423
-
Heterogeneity, histological features and DNA ploidy in oral carcinoma by image-based analysis
-
Diwakar N, Sperandio M, Sherriff M, et al. Heterogeneity, histological features and DNA ploidy in oral carcinoma by image-based analysis. Oral Oncol 2005; 41: 416–422.
-
(2005)
Oral Oncol
, vol.41
, pp. 416-422
-
-
Diwakar, N.1
Sperandio, M.2
Sherriff, M.3
-
46
-
-
0024814212
-
Morphometric analysis, ploidy and response to chemotherapy in squamous carcinomas of the head and neck
-
Helliwell TR, Atkinson MW, Cooke TG, et al. Morphometric analysis, ploidy and response to chemotherapy in squamous carcinomas of the head and neck. Pathol Res Pract 1989; 185: 755–759.
-
(1989)
Pathol Res Pract
, vol.185
, pp. 755-759
-
-
Helliwell, T.R.1
Atkinson, M.W.2
Cooke, T.G.3
-
47
-
-
0035741513
-
DNA ploidy and S-phase fraction in carcinoma of the gallbladder related to histopathology, number of gallstones and survival
-
Gustafsson U, Einarsson C, Eriksson LC, et al. DNA ploidy and S-phase fraction in carcinoma of the gallbladder related to histopathology, number of gallstones and survival. Anal Cell Pathol 2001; 23: 143–152.
-
(2001)
Anal Cell Pathol
, vol.23
, pp. 143-152
-
-
Gustafsson, U.1
Einarsson, C.2
Eriksson, L.C.3
-
48
-
-
0025220357
-
Primary sarcomas of the kidney. A clinicopathologic and DNA flow cytometric study of 17 cases
-
Grignon DJ, Ayala AG, Ro JY, et al. Primary sarcomas of the kidney. A clinicopathologic and DNA flow cytometric study of 17 cases. Cancer 1990; 65: 1611–1618.
-
(1990)
Cancer
, vol.65
, pp. 1611-1618
-
-
Grignon, D.J.1
Ayala, A.G.2
Ro, J.Y.3
-
49
-
-
84882976632
-
Identifying survival associated morphological features of triple negative breast cancer using multiple datasets
-
Wang C, Pecot T, Zynger DL, et al. Identifying survival associated morphological features of triple negative breast cancer using multiple datasets. J Am Med Inform Assoc 2013; 20: 680–687.
-
(2013)
J Am Med Inform Assoc
, vol.20
, pp. 680-687
-
-
Wang, C.1
Pecot, T.2
Zynger, D.L.3
-
50
-
-
85044249124
-
Towards generation, management, and exploration of combined radiomics and pathomics datasets for cancer research
-
Saltz J, Almeida J, Gao Y, et al. Towards generation, management, and exploration of combined radiomics and pathomics datasets for cancer research. AMIA Jt Summits Transl Sci Proc 2017; 2017: 85–94.
-
(2017)
AMIA Jt Summits Transl Sci Proc
, vol.2017
, pp. 85-94
-
-
Saltz, J.1
Almeida, J.2
Gao, Y.3
-
51
-
-
85035006218
-
A containerized software system for generation, management, and exploration of features from whole slide tissue images
-
e79–
-
Saltz J, Sharma A, Iyer G, et al. A containerized software system for generation, management, and exploration of features from whole slide tissue images. Cancer Res 2017; 77: e79–e82.
-
(2017)
Cancer Res
, vol.77
-
-
Saltz, J.1
Sharma, A.2
Iyer, G.3
-
52
-
-
84860247330
-
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma
-
Cooper LA, Gutman DA, Chisolm C, et al. The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. Am J Pathol 2012; 180: 2108–2119.
-
(2012)
Am J Pathol
, vol.180
, pp. 2108-2119
-
-
Cooper, L.A.1
Gutman, D.A.2
Chisolm, C.3
-
53
-
-
85032892753
-
Interactive phenotyping of large-scale histology imaging data with HistomicsML
-
14588
-
Nalisnik M, Amgad M, Lee S, et al. Interactive phenotyping of large-scale histology imaging data with HistomicsML. Sci Rep 2017; 7: 14588.
-
(2017)
Sci Rep
, vol.7
-
-
Nalisnik, M.1
Amgad, M.2
Lee, S.3
-
54
-
-
85018562763
-
Identification of histological correlates of overall survival in lower grade gliomas using a bag-of-words paradigm: a preliminary analysis based on hematoxylin & eosin stained slides from the lower grade glioma cohort of The Cancer Genome Atlas
-
Powell RT, Olar A, Narang S, et al. Identification of histological correlates of overall survival in lower grade gliomas using a bag-of-words paradigm: a preliminary analysis based on hematoxylin & eosin stained slides from the lower grade glioma cohort of The Cancer Genome Atlas. J Pathol Inform 2017; 8: 9.
-
(2017)
J Pathol Inform
, vol.8
, pp. 9
-
-
Powell, R.T.1
Olar, A.2
Narang, S.3
|