Comparative genomics and transcriptomics analysis-guided metabolic engineering of Propionibacterium acidipropionici for improved propionic acid production

Biotechnology and Bioengineering

Volumn 115, Issue 2, 2018, Pages 483-494

  Guan, Ningzi ^a,b   Du, Bin ^c   Li, Jianghua ^a   Shin, Hyun Dong ^b   Chen, Rachel R ^b   Du, Guocheng ^a   Chen, Jian ^a   Liu, Long ^a  

^a JIANGNAN UNIVERSITY   (China)

^b Georgia Institute of Technology   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

acid resistance; genomics; metabolic engineering; Propionibacterium acidipropionici; transcriptomics

Indexed keywords

ACETIC ACID; ACID RESISTANCE; BALANCING; CYTOLOGY; FERMENTATION; GENES; LACTIC ACID; METABOLIC ENGINEERING; METABOLISM; PH; SATURATED FATTY ACIDS; SYNTHETIC BIOLOGY;

COMPARATIVE GENOMICS; GENOMICS; MICROBIAL CELL FACTORIES; MICROBIAL PRODUCTION; PROPIONIBACTERIUM ACIDIPROPIONICI; RESISTANCE MECHANISMS; TRANSCRIPTOMICS; TRANSMEMBRANE TRANSPORT;

PROPIONIC ACID;

ACETIC ACID; AMINO ACID; GENOMIC DNA; ION; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE 1; LACTATE DEHYDROGENASE 2; LACTIC ACID; PROPIONIC ACID; PROTON; UNCLASSIFIED DRUG; ACID; PROPIONIC ACID DERIVATIVE;

ACID TOLERANCE; ACIDITY; AMINO ACID METABOLISM; ARTICLE; CELL PROTECTION; COMPARATIVE STUDY; DNA DAMAGE; DOWN REGULATION; ENERGY METABOLISM; GENE; GENE EXPRESSION; GENE KNOCKOUT; GENETIC CODE; GENOMICS; MACROMOLECULE; METABOLIC ENGINEERING; NONHUMAN; PH; POXB GENE; PROPIONIBACTERIUM ACIDIPROPIONICI; PROTEIN EXPRESSION; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SYNTHETIC BIOLOGY; TRANSCRIPTOMICS; WILD TYPE; ADAPTATION; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PHYSIOLOGY; PROCEDURES; PROPIONIBACTERIUM;

ACIDS; ADAPTATION, BIOLOGICAL; GENE EXPRESSION PROFILING; GENOMICS; METABOLIC ENGINEERING; PROPIONATES; PROPIONIBACTERIUM;

EID: 85041901302     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.26478     Document Type: Article

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